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List of works by Hartmut Kühn

A structural model for the interaction of haem with unsaturated fatty acids explaining its quasi-lipoxygenase activity. Quantum chemical calculations

scientific article published on 01 January 1983

A test hierarchy for anti-bronchoconstrictory lipoxygenase inhibitors: in vitro and in vivo experimental tests.

scientific article published in May 1987

Alterations of lipoxygenase specificity by targeted substrate modification and site-directed mutagenesis

scientific article published in August 2001

Analysis of the stereochemistry of lipoxygenase-derived hydroxypolyenoic fatty acids by means of chiral phase high-pressure liquid chromatography

scientific article published in January 1987

Bacterial and nonbacterial expression of wild-type and mutant human phospholipid hydroperoxide glutathione peroxidase and purification of the mutant enzyme in the milligram scale

scientific article published on August 2000

Catalytic activities of haemoglobin related to lipid peroxidation

scientific article published on 01 January 1983

Cloning of the mouse phospholipid hydroperoxide glutathione peroxidase gene

scientific article

Do 15-lipoxygenases have a common biological role? ⬇️

scientific article published on October 1, 1991

Evidence for the presence of lipoxygenase pathway in cultured endothelial cells

scientific article published on 01 January 1983

Flavonoids of cocoa inhibit recombinant human 5-lipoxygenase. ⬇️

scientific article published in July 2002

Formation of ketodienoic fatty acids by the pure pea lipoxygenase-1.

scientific article published in January 1991

Formation of lipoxin B by the pure reticulocyte lipoxygenase

scientific article published on 01 November 1986

Formation of oxygenase and hydroperoxidase products by the pure reticulocyte lipoxygenase

scientific article published in January 1990

Hydroperoxyfatty acids inactivate the reticulocyte lipoxygenase independently of a hydroperoxidase reaction

scientific article published on 01 July 1986

Identification of oxidatively modified lipids in atherosclerotic lesions of human aortas

scientific article published in January 1992

Inactivation of 15-lipoxygenases by acetylenic fatty acids

scientific article published on January 1, 1991

Inhibition of cell migrations by the linoleic acid oxygenation product 9S-hydroxy 10E,12Z octadecadienoic acid (9-HODE).

scientific article published on January 1988

Interleukin-4 and -13 induce upregulation of the murine macrophage 12/15-lipoxygenase activity: evidence for the involvement of transcription factor STAT6 ⬇️

scientific article published on 01 October 1998

Intra- and Extracellular Expression of Rabbit Reticulocyte 15-Lipoxygenase in the Baculovirus/Insect Cell System ⬇️

scientific article published on November 1, 1998

Inverse regulation of lipid-peroxidizing and hydroperoxyl lipid-reducing enzymes by interleukins 4 and 13.

scientific article published in January 1999

Keto fatty acids not containing doubly allylic methylenes are lipoxygenase substrates

scientific article published in October 1991

Lipoxygenase treatment render low-density lipoprotein susceptible to Cu2+-catalysed oxidation

scientific article published on March 1996

Macrophage cholesteryl ester hydrolases and hormone-sensitive lipase prefer specifically oxidized cholesteryl esters as substrates over their non-oxidized counterparts

scientific article

Membrane translocation of 15-lipoxygenase in hematopoietic cells is calcium-dependent and activates the oxygenase activity of the enzyme ⬇️

scientific article published on January 1, 1998

Metabolism of [1-14C]-arachidonic acid by cultured calf aortic endothelial cells: evidence for the presence of a lipoxygenase pathway.

scientific article

Metabolism of polyenoic fatty acids by rabbit reticulocytes. Intracellular action of the erythroid lipoxygenase on membrane lipids.

scientific article published in January 1990

Metabolism of polyenoic fatty acids by red blood cells.

scientific article published in January 1987

Nitric oxide oxidises a ferrous mammalian lipoxygenase to a pre-activated ferric species

scientific article

Omega-oxidation impairs oxidizability of polyenoic fatty acids by 15-lipoxygenases: consequences for substrate orientation at the active site

scientific article published on December 1998

On the nature of the stimulation of the lipoxygenase from rabbit reticulocytes by biological membranes

scientific article published on 01 January 1985

On the reaction of wheat lipoxygenase with arachidonic acid and its oxygenated derivatives

scientific article published in January 1991

Oxidative modification of human lipoproteins by lipoxygenases of different positional specificities.

scientific article published in October 1994

Oxygenation of biological membranes by the reticulocyte lipoxygenase. Lack of stoichiometry between oxygen uptake and product formation.

scientific article published in January 1990

Oxygenation of biomembranes by mammalian lipoxygenases: the role of ubiquinone

scientific article

Oxygenation of mitochondrial membranes by the erythroid lipoxygenase. Consequences for membrane properties

scientific article published in January 1990

Polyphenols of cocoa: inhibition of mammalian 15-lipoxygenase

scientific article published in December 2001

Positional specificity of lipoxygenases and their suitability for testing potential drugs

scientific article

Probing the Substrate Alignment at the Active Site of 15-Lipoxygenases by Targeted Substrate Modification and Site-Directed Mutagenesis. Evidence for an Inverse Substrate Orientation ⬇️

scientific article published on November 3, 1998

Pure enzymes in a test hierarchy for antibronchoconstrictory lipoxygenase inhibitors.

scientific article

Regulation of 15-lipoxygenase expression in lung epithelial cells by interleukin-4.

scientific article

Requirement of monohydroperoxy fatty acids for the oxygenation of 15LS-HETE by reticulocyte lipoxygenase

scientific article published on July 1986

Reticulocyte lipoxygenase exhibits both n-6 and n-9 activities

scientific article published on 01 March 1983

Shape and specificity in mammalian 15-lipoxygenase active site. The functional interplay of sequence determinants for the reaction specificity

scientific article published in December 1999

Simultaneous expression of leukocyte-type 12-lipoxygenase and reticulocyte-type 15-lipoxygenase in rabbits 1 1Edited by F. Cohen ⬇️

scientific article published on May 22, 1998

Structure elucidation of oxygenated lipids in human atherosclerotic lesions.

scientific article published in January 1992

Test hierarchy for the development of new drug action principles with the action site in phospholipid metabolism for bronchial asthma and pulmonary hypertension

scientific article

The Rabbit 15-Lipoxygenase Preferentially Oxygenates LDL Cholesterol Esters, and This Reaction Does Not Require Vitamin E ⬇️

scientific article published on September 4, 1998

The biological dynamics of lipoxygenase in rabbit red cells in the course of an experimental bleeding anaemia. Unexpected effects of the calcium ionophore A 23187.

scientific article

The diversity of the lipoxygenase family. Many sequence data but little information on biological significance

scientific article

The erythroid arachidonate 15-lipoxygenase in rat reticulocytes

scientific article published on 01 January 1990

The formation of products containing a conjugated tetraenoic system by pure reticulocyte lipoxygenase

scientific article published on 01 November 1984

The inactivation of lipoxygenases by acetylenic fatty acids

scientific article published on 01 January 1984

The inhibition of mammalian 15-lipoxygenases by the anti-inflammatory drug ebselen: dual-type mechanism involving covalent linkage and alteration of the iron ligand sphere

scientific article published in July 1999

The iron ligand sphere geometry of mammalian 15-lipoxygenases ⬇️

scientific article published on May 15, 1998

The linoleic acid metabolite 9DS-hydroxy-10,12(E,Z)-octadecadienoic acid is a strong proinflammatory mediator in an experimental wound healing model of the rat.

scientific article published in January 1990

The occurrence of a lipoxygenase pathway in reticulocytes of various species

scientific article published on 01 January 1986

The oxygenation of cholesterol esters by the reticulocyte lipoxygenase

scientific article published on 01 February 1991

The possible biological importance of lipoxygenase pathway in aorta endothelial cells.

scientific article published in January 1984

[Biotransformation of the lipoxygenase inhibitor 2-hydroxy-5-methyl-laurophenone-oxime (FLM 5011)]

scientific article published on 01 June 1996

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