List of works - Peter Walsmann

125I-labeling of hirudin

scientific article published in July 1986

A thrombin binding assay for 125I-hirudin

scientific article published on 01 May 1988

Benzamidine derivatives--relationship between antithrombin activity and structure

scientific article published on 01 January 1982

Comparative Studies on the Inhibition of Trypsin, Plasmin, and Thrombin by Derivatives of Benzylamine and Benzamidine ⬇️

scientific article published on 01 December 1968

Cyclic amides of N alpha-arylsulfonylaminoacylated 4-amidinophenylalanine--tight binding inhibitors of thrombin

scientific article published on 01 March 1983

Evidence for the identity of hirudin isolated after kidney passage with the starting material

scientific article published in January 1988

Hirudin as a diagnostic agent

scientific article published on January 1988

Hirudin binding to soluble dextran.

scientific article

Inactivation of trypsin and thrombin by 4-amidinobenzolsulfofluoride and 4-(2-aminoethyl)-benzolsulfofluoride

scientific article published on 01 January 1972

Influence of benzamidine derivatives on the activity of serum and pancreatic kallikrein

scientific article published on 01 January 1971

Inhibition of bovine and human thrombins by derivatives of benzamidine

scientific article published on 01 December 1984

Inhibition of serine proteinases by benzamidine derivatives

scientific article published on January 1, 1977

Inhibition of trypsin and thrombin by amidinophenyl esters of aromatic carboxylic acids

scientific article published on 01 January 1972

Isolation and characterization of a thrombin inhibitor from the tick ixodes ricinus

scientific article published on 01 March 1991

Isolation and characterization of hirudin from Hirudo medicinalis

scientific article published on April 1991

Isolation of hirudin from medicinal leech

scientific article published on 01 May 1967

Isolation of hiruin from the medicinal leech

scientific article published on 01 May 1967

N alpha-arylsulfonyl-omega-(4-amidinophenyl)-alpha-aminoalkylcarboxylic acid amides--novel selective inhibitors of thrombin

scientific article published on 01 February 1980

Neutralization of hirudin anticoagulant action by DIP-thrombin.

scientific article published in September 1989

On the biochemistry of thrombins

scientific article published on 01 November 1968

On the isolation of the thrombin inhibitor hirudin.

scientific article published in November 1985

On the purification of thrombin preparations

scientific article published on 01 July 1968

Pharmacokinetics and anticoagulant effect of hirudin in man.

scientific article published in October 1984

Pharmacokinetics of 125I-hirudin in rats and dogs.

scientific article published in January 1988

Pharmacological studies on the antithrombotic action of hirudin in experimental animals

scientific article published on 01 June 1982

Plasma level of dextran-r-hirudin

scientific article published on 01 January 1989

Preparation of dextran-bound recombinant hirudin and its pharmacokinetic behaviour

scientific article published on 01 January 1990

Purification and analysis of the thrombin inhibitor hirudin

scientific article published in November 1967

Quality control of 125I-labelled fibrinogen of various species.

scientific article published on January 1988

Structure-Activity Relationships of Recombinant Hirudins ⬇️

scientific article published on April 1, 1991

Studies on the pharmacokinetics of hirudin.

scientific article

Synthesis of antiproteolytic effective derivatives of benzylamine and benzamidine

scientific article published on 01 July 1969

Synthetic inhibitors of serine proteinases XIV.+) inhibition of Factor Xa by derivatives of benzamidine

scientific article published on 01 December 1976

Synthetic inhibitors of serine proteinases. 10. The inhibition of trypsin, plasmin and thrombin by 4-amidinophenylaralkanone

scientific article published on January 1, 1976

Synthetic inhibitors of serine proteinases. 11.Report: The inhibition of trypsin, plasmin and thrombin by new bisamidino compounds

scientific article published on January 1, 1976

Synthetic inhibitors of serine proteinases. 12. The inhibition of trypsin, plasmin and thrombin by 3-[amidinophenyl]-1-phenyl-propanone-(1) with substituents in the aliphatic intermediate chain

scientific article (publication date: June 1976)

Synthetic inhibitors of serine proteinases. 13. Quantitative structure-activity relationship for inhibition of trypsin and thrombin by 4-amidinophenyl compounds with a ketone structure

scientific article published on January 1, 1976

Synthetic inhibitors of serine proteinases. 15. Antitrypsin, antiplasmin and antithrombin effect of 2-amino-6-alkoxy- and aralkoxynaphthalenes

scientific article published on December 1, 1977

Synthetic inhibitors of serine proteinases. 18. Inhibition of trypsin, plasmin and thrombin by derivatives of naphthamidine and ketone structure

scientific article published on November 1, 1978

Synthetic inhibitors of serine proteinases. 20. The inhibitory effect of benzo condensed lactam derivatives of benzamidine on trypsin, plasmin and thrombin

scientific article published on January 1, 1979

Synthetic inhibitors of serine proteinases. 31. The inhibition of trypsin, plasmin and thrombin by isomeric compounds of N alpha -arylsulfonylated omega-amidinophenyl-alpha-aminoalkylcarboxylic acid amides

scientific article published on 01 June 1984

Synthetic inhibitors of serine proteinases. 34. The effect of modification of the amidino function of N-alpha-substituted 4-amidinophenylalanine amides on inhibitory activity

scientific article published on November 1988

Synthetic inhibitors of serine proteinases. 5. The inhibition of trypsin, plasmin and thrombin caused by aliphatic amidino compounds having ether structure as well as esters of the 3- and 4-amidinophenoxyfacetic acid

scientific article published on June 1, 1975

Synthetic inhibitors of serine proteinases. 7. Inhibition of trypsin, plasmin and thrombin by amidinobenzylarylsulfides and -sulfones as well as N-(amidinobenzyl)-N-(aryl)- and N-(amidinobenzyl)-N-(arylalkyl)amines

scientific article published on January 1, 1976

Synthetic inhibitors of serine proteinases. 8. Inhibition of trypsin, plasmin and thrombin by means of amidinophenyl-derivatives with ketonic-structure

scientific article published on July 1, 1976

Synthetic inhibitors of serine proteinases. 9. The inhibition of tryspsin,plasmin and thrombin by amidinophenyl-, amidinobenzyl- and beta-(amidinophenyl)ethylarylketons

scientific article published on January 1, 1976

Synthetic inhibitors of serine proteinases. Part 19: On the inhibitory effect of amidinobenzylidene derivatives of benzo-condensed cycloalkanones on trypsin, plasmin and thrombin (author's transl)

scientific article published on January 1, 1979

Synthetic inhibitors of serine proteinases. Part 21: Studies on the structure-activity relationships in bisamidines (author's transl)

scientific article published on December 1, 1979

Synthetic inhibitors of serine proteinases. Part 26: Inhibition of trypsin, plasmin and thrombin by amides of N alpha-arylsulfonylated 2-amino-4-(4-amidino-phenyl) butyric acid and 2-amino-5-amidinophenyl valeric acids (author's transl)

scientific article published on April 1982

Synthetic inhibitors of serine proteinases. XVI. Influence of 3- and 4-amidinobenzyl derivatives on the formation and action of thrombin

scientific article published on 01 May 1978

Synthetic inhibitors of serine proteinases. XXIII. Inhibition of factor Xa by diamidines

scientific article published on 01 February 1980

Synthetic low molecular weight inhibitors of serum kallikrein ⬇️

scientific article published on August 15, 1974

Synthetic serin protease inhibitors. 1. Inhibition of trypsin, plasmin and thrombin by amidino- and guanidinobenzoic acid esters

scientific article published on 01 May 1973

Synthetic serine protease inhibitors. 29. Synthesis of alpha-arylsulphonylamino-beta-(4-amidinophenyl)ethyl-chloromethylketones and their inhibitory activity against trypsin, plasmin and thrombin

scientific article published on September 1983

Synthetic serine proteinase inhibitors. 30. Synthesis of alpha-benzoylamino-4-amidinocinnamic acid and alpha-(4-amidinobenzoylamino) cinnamic acid amides, and their inhibitory effect on trypsin-like enzymes

scientific article published on December 1, 1983

The effect of synthetic trypsin inhibitors on the kinin-liberating effect of trypsin and pancreatic kallikrein

scientific article published on 01 January 1970

The hirudin standard

scientific article published on 01 July 1990

The inhibition of trypsin, plasmin, and thrombin by benzyl 4-guanidinobenzoate and 4'-nitrobenzyl 4-guanidinobenzoate

scientific article published on 01 June 1970

[Aminoalkylbenzolsulfofluorides as ferment inhibitors]

scientific article published on 01 July 1971

[Biochemical and pharmacological aspects of the thrombin inhibitor hirudin]

scientific article published on 01 October 1981

[Determination of the molecular weight of hirudin in the ultracentrifuge]

scientific article published on 01 May 1966

[Influence of synthetic proteinase inhibitors on the effect and activation of proteolytic enzymes of the pancreas]

scientific article published on 01 January 1974

[Inhibition of thrombin, plasmin and trypsin effect by alkyl- and alkoxybenzamidine]

scientific article published on 01 September 1970

[Modification of thrombin activity by synthetic serine proteinase inhibitors]

[On inhibition of the coagulation enzyme thrombin by benzamidine derivatives]

scientific article published on 01 January 1968

[Production and characterization of a soluble ocrase-polyacrylamide preparation (author's transl)]

scientific article published on 01 January 1981

[Recent developments in the biochemistry of hirudins]

scientific article published on 01 January 1989

[Studies on the effect of ring substitution on the thrombin inhibition effect of benzylamine- and benzamidine derivatives]

scientific article published on 01 July 1969

[Synthetic inhibitors of serine proteinases. 2. Inhibitory effect of amidino benzoic acid homologues and of their esters in comparison with trypsin, plasmin and thrombin]

scientific article published on 01 May 1974

[Synthetic inhibitors of serine proteinases. 27. The inhibitory effects of amides of 4-amidinophenylacetic acid and 4-amidinophenoxyacetic acid]

scientific article published on 01 June 1981

[Synthetic inhibitors of serine proteinases. 28. The inhibitory effect of esters of N-alpha-arylsulfonyl-4-amidinophenylalanine against trypsin, plasmin and thrombin]

scientific article published on 01 June 1982

[Synthetic inhibitors of serine proteinases. 3. Inhibitory effect of basic ally substituted phenyl carbonic acid esters in comparison with trypsin, plasmin and thrombin]

scientific article published on 01 May 1974

[Synthetic inhibitors of serine proteinases. 32. Inhibition of trypsin, plasmin and thrombin by amides of N-alpha-substituted 4-amidinophenylalanine. Effect of various amino acids and blocking groups of the n-alpha residue on inhibitory activity]

scientific article published on 01 February 1987

[Synthetic inhibitors of serine proteinases. 4.: Inhibitory effect of substituted anilides of 3- and 4- amidino benzoic acid and amidino-anilides of different benzoic- and benzene sulfonic acids]

scientific article published on 01 June 1974

[Synthetic inhibitors of serine proteinases. Part 24: Inhibition of trypsin, plasmin and thrombin by cyclic amides of N alpha-arylsulfonylamidinophenyl-glycines (author's transl)]

scientific article published on 01 January 1981

[Synthetic inhibitors of serine proteinases. Part 25: Inhibition of trypsin, plasmin and thrombin by amides of N alpha-substituted amidinophenylalanines and 3-amidinophenyl-3-aminopropionic acids (author's transl)]

scientific article published on 01 September 1981

[Synthetic serine proteinase inhibitors. 6. Inhibition of trypsin, plasmin and thrombin by phenylpyruvic acids containing various basic groups]

scientific article published on 01 January 1974

[The use of the specific thrombin inhibitor hirudin in diagnostic and biochemical studies]

scientific article published on 01 November 1988

List of works by Peter Walsmann

125I-labeling of hirudin

A thrombin binding assay for 125I-hirudin

Benzamidine derivatives--relationship between antithrombin activity and structure

Comparative Studies on the Inhibition of Trypsin, Plasmin, and Thrombin by Derivatives of Benzylamine and Benzamidine ⬇️

Cyclic amides of N alpha-arylsulfonylaminoacylated 4-amidinophenylalanine--tight binding inhibitors of thrombin

Evidence for the identity of hirudin isolated after kidney passage with the starting material

Hirudin as a diagnostic agent

Hirudin binding to soluble dextran.

Inactivation of trypsin and thrombin by 4-amidinobenzolsulfofluoride and 4-(2-aminoethyl)-benzolsulfofluoride

Influence of benzamidine derivatives on the activity of serum and pancreatic kallikrein

Inhibition of bovine and human thrombins by derivatives of benzamidine

Inhibition of serine proteinases by benzamidine derivatives

Inhibition of trypsin and thrombin by amidinophenyl esters of aromatic carboxylic acids

Isolation and characterization of a thrombin inhibitor from the tick ixodes ricinus

Isolation and characterization of hirudin from Hirudo medicinalis

Isolation of hirudin from medicinal leech

Isolation of hiruin from the medicinal leech

N alpha-arylsulfonyl-omega-(4-amidinophenyl)-alpha-aminoalkylcarboxylic acid amides--novel selective inhibitors of thrombin

Neutralization of hirudin anticoagulant action by DIP-thrombin.

On the biochemistry of thrombins

On the isolation of the thrombin inhibitor hirudin.

On the purification of thrombin preparations

Pharmacokinetics and anticoagulant effect of hirudin in man.

Pharmacokinetics of 125I-hirudin in rats and dogs.

Pharmacological studies on the antithrombotic action of hirudin in experimental animals

Plasma level of dextran-r-hirudin

Preparation of dextran-bound recombinant hirudin and its pharmacokinetic behaviour

Purification and analysis of the thrombin inhibitor hirudin

Quality control of 125I-labelled fibrinogen of various species.

Structure-Activity Relationships of Recombinant Hirudins ⬇️

Studies on the pharmacokinetics of hirudin.

Synthesis of antiproteolytic effective derivatives of benzylamine and benzamidine

Synthetic inhibitors of serine proteinases XIV.+) inhibition of Factor Xa by derivatives of benzamidine

Synthetic inhibitors of serine proteinases. 10. The inhibition of trypsin, plasmin and thrombin by 4-amidinophenylaralkanone

Synthetic inhibitors of serine proteinases. 11.Report: The inhibition of trypsin, plasmin and thrombin by new bisamidino compounds

Synthetic inhibitors of serine proteinases. 12. The inhibition of trypsin, plasmin and thrombin by 3-[amidinophenyl]-1-phenyl-propanone-(1) with substituents in the aliphatic intermediate chain

Synthetic inhibitors of serine proteinases. 13. Quantitative structure-activity relationship for inhibition of trypsin and thrombin by 4-amidinophenyl compounds with a ketone structure

Synthetic inhibitors of serine proteinases. 15. Antitrypsin, antiplasmin and antithrombin effect of 2-amino-6-alkoxy- and aralkoxynaphthalenes

Synthetic inhibitors of serine proteinases. 18. Inhibition of trypsin, plasmin and thrombin by derivatives of naphthamidine and ketone structure

Synthetic inhibitors of serine proteinases. 20. The inhibitory effect of benzo condensed lactam derivatives of benzamidine on trypsin, plasmin and thrombin

Synthetic inhibitors of serine proteinases. 31. The inhibition of trypsin, plasmin and thrombin by isomeric compounds of N alpha -arylsulfonylated omega-amidinophenyl-alpha-aminoalkylcarboxylic acid amides

Synthetic inhibitors of serine proteinases. 34. The effect of modification of the amidino function of N-alpha-substituted 4-amidinophenylalanine amides on inhibitory activity

Synthetic inhibitors of serine proteinases. 5. The inhibition of trypsin, plasmin and thrombin caused by aliphatic amidino compounds having ether structure as well as esters of the 3- and 4-amidinophenoxyfacetic acid

Synthetic inhibitors of serine proteinases. 7. Inhibition of trypsin, plasmin and thrombin by amidinobenzylarylsulfides and -sulfones as well as N-(amidinobenzyl)-N-(aryl)- and N-(amidinobenzyl)-N-(arylalkyl)amines

Synthetic inhibitors of serine proteinases. 8. Inhibition of trypsin, plasmin and thrombin by means of amidinophenyl-derivatives with ketonic-structure

Synthetic inhibitors of serine proteinases. 9. The inhibition of tryspsin,plasmin and thrombin by amidinophenyl-, amidinobenzyl- and beta-(amidinophenyl)ethylarylketons

Synthetic inhibitors of serine proteinases. Part 19: On the inhibitory effect of amidinobenzylidene derivatives of benzo-condensed cycloalkanones on trypsin, plasmin and thrombin (author's transl)

Synthetic inhibitors of serine proteinases. Part 21: Studies on the structure-activity relationships in bisamidines (author's transl)

Synthetic inhibitors of serine proteinases. Part 26: Inhibition of trypsin, plasmin and thrombin by amides of N alpha-arylsulfonylated 2-amino-4-(4-amidino-phenyl) butyric acid and 2-amino-5-amidinophenyl valeric acids (author's transl)

Synthetic inhibitors of serine proteinases. XVI. Influence of 3- and 4-amidinobenzyl derivatives on the formation and action of thrombin

Synthetic inhibitors of serine proteinases. XXIII. Inhibition of factor Xa by diamidines

Synthetic low molecular weight inhibitors of serum kallikrein ⬇️

Synthetic serin protease inhibitors. 1. Inhibition of trypsin, plasmin and thrombin by amidino- and guanidinobenzoic acid esters

Synthetic serine protease inhibitors. 29. Synthesis of alpha-arylsulphonylamino-beta-(4-amidinophenyl)ethyl-chloromethylketones and their inhibitory activity against trypsin, plasmin and thrombin

Synthetic serine proteinase inhibitors. 30. Synthesis of alpha-benzoylamino-4-amidinocinnamic acid and alpha-(4-amidinobenzoylamino) cinnamic acid amides, and their inhibitory effect on trypsin-like enzymes

The effect of synthetic trypsin inhibitors on the kinin-liberating effect of trypsin and pancreatic kallikrein

The hirudin standard

The inhibition of trypsin, plasmin, and thrombin by benzyl 4-guanidinobenzoate and 4'-nitrobenzyl 4-guanidinobenzoate

[Aminoalkylbenzolsulfofluorides as ferment inhibitors]

[Biochemical and pharmacological aspects of the thrombin inhibitor hirudin]

[Determination of the molecular weight of hirudin in the ultracentrifuge]

[Influence of synthetic proteinase inhibitors on the effect and activation of proteolytic enzymes of the pancreas]

[Inhibition of thrombin, plasmin and trypsin effect by alkyl- and alkoxybenzamidine]

[Modification of thrombin activity by synthetic serine proteinase inhibitors]

[On inhibition of the coagulation enzyme thrombin by benzamidine derivatives]

[Production and characterization of a soluble ocrase-polyacrylamide preparation (author's transl)]

[Recent developments in the biochemistry of hirudins]

[Studies on the effect of ring substitution on the thrombin inhibition effect of benzylamine- and benzamidine derivatives]

[Synthetic inhibitors of serine proteinases. 2. Inhibitory effect of amidino benzoic acid homologues and of their esters in comparison with trypsin, plasmin and thrombin]

[Synthetic inhibitors of serine proteinases. 27. The inhibitory effects of amides of 4-amidinophenylacetic acid and 4-amidinophenoxyacetic acid]

[Synthetic inhibitors of serine proteinases. 28. The inhibitory effect of esters of N-alpha-arylsulfonyl-4-amidinophenylalanine against trypsin, plasmin and thrombin]

[Synthetic inhibitors of serine proteinases. 3. Inhibitory effect of basic ally substituted phenyl carbonic acid esters in comparison with trypsin, plasmin and thrombin]

[Synthetic inhibitors of serine proteinases. 32. Inhibition of trypsin, plasmin and thrombin by amides of N-alpha-substituted 4-amidinophenylalanine. Effect of various amino acids and blocking groups of the n-alpha residue on inhibitory activity]

[Synthetic inhibitors of serine proteinases. 4.: Inhibitory effect of substituted anilides of 3- and 4- amidino benzoic acid and amidino-anilides of different benzoic- and benzene sulfonic acids]

[Synthetic inhibitors of serine proteinases. Part 24: Inhibition of trypsin, plasmin and thrombin by cyclic amides of N alpha-arylsulfonylamidinophenyl-glycines (author's transl)]

[Synthetic inhibitors of serine proteinases. Part 25: Inhibition of trypsin, plasmin and thrombin by amides of N alpha-substituted amidinophenylalanines and 3-amidinophenyl-3-aminopropionic acids (author's transl)]

[Synthetic serine proteinase inhibitors. 6. Inhibition of trypsin, plasmin and thrombin by phenylpyruvic acids containing various basic groups]

[The use of the specific thrombin inhibitor hirudin in diagnostic and biochemical studies]

[Use of hirudin in clinical coagulation laboratories]