List of works by Ikbel Achour

'N-of-1-pathways' unveils personal deregulated mechanisms from a single pair of RNA-Seq samples: towards precision medicine

scientific article

A genome-by-environment interaction classifier for precision medicine: personal transcriptome response to rhinovirus identifies children prone to asthma exacerbations

scientific article published on November 2017

Analysis of aggregated cell-cell statistical distances within pathways unveils therapeutic-resistance mechanisms in circulating tumor cells

scientific article published on June 2016

Concordance of deregulated mechanisms unveiled in underpowered experiments: PTBP1 knockdown case study

scientific article

Design and efficacy of a monovalent bispecific PD-1/CTLA-4 antibody that enhances CTLA-4 blockade on PD-1+ activated T cells

scientific article published on 08 January 2021

Dynamic changes of RNA-sequencing expression for precision medicine: N-of-1-pathways Mahalanobis distance within pathways of single subjects predicts breast cancer survival

scientific article published on June 2015

In Silico cancer cell versus stroma cellularity index computed from species-specific human and mouse transcriptome of xenograft models: towards accurate stroma targeting therapy assessment.

scientific article

Integrative genomics analyses unveil downstream biological effectors of disease-specific polymorphisms buried in intergenic regions

scientific article published on 27 April 2016

N-of-1-pathways MixEnrich: advancing precision medicine via single-subject analysis in discovering dynamic changes of transcriptomes

scientific article

Network models of genome-wide association studies uncover the topological centrality of protein interactions in complex diseases

scientific article (publication date: 2013)

The discriminatory cost of ICD-10-CM transition between clinical specialties: metrics, case study, and mitigating tools

scientific article

eQTL networks unveil enriched mRNA master integrators downstream of complex disease-associated SNPs.

scientific article published on 30 October 2015

kMEn: Analyzing noisy and bidirectional transcriptional pathway responses in single subjects

scientific article published on 19 December 2016

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