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List of works by Thomas R Kreil

A Pandemic Influenza H1N1 Live Vaccine Based on Modified Vaccinia Ankara Is Highly Immunogenic and Protects Mice in Active and Passive Immunizations ⬇️

scientific article (publication date: 16 August 2010)

A Vero Cell–Derived Whole-Virus H5N1 Vaccine Effectively Induces Neuraminidase-Inhibiting Antibodies ⬇️

scientific article published on November 16, 2011

A cell culture-derived whole-virus H5N1 vaccine induces long-lasting cross-clade protective immunity in mice which is augmented by a homologous or heterologous booster vaccination ⬇️

scientific article published on June 29, 2012

A cell culture-derived whole-virus H9N2 vaccine induces high titer antibodies against hemagglutinin and neuraminidase and protects mice from severe lung pathology and weight loss after challenge with a highly virulent H9N2 isolate ⬇️

scientific article published on May 10, 2012

A nonenveloped virus with a lipid envelope: hepatitis A virus as used in virus-reduction studies

scientific article published on 28 March 2017

A tick-borne encephalitis virus vaccine based on the European prototype strain induces broadly reactive cross-neutralizing antibodies in humans

scientific article published on June 2011

A whole virus pandemic influenza H1N1 vaccine is highly immunogenic and protective in active immunization and passive protection mouse models.

scientific article

Antibody-enhanced hepatitis E virus nanofiltration during the manufacture of human immunoglobulin

scientific article published on 13 August 2020

Blood transmission studies of prion infectivity in the squirrel monkey (Saimiri sciureus): the Baxter study

scientific article

Characterization of 100 sequential SARS-CoV-2 convalescent plasma donations

scientific article published on 25 September 2020

Characterization of source plasma from self-identified vaccinated or convalescent donors during the 2009 H1N1 pandemic

scientific article published on 15 February 2018

Chikungunya virus and the safety of plasma products ⬇️

scientific article published on February 17, 2012

Clinical, neuropathological and immunohistochemical features of sporadic and variant forms of Creutzfeldt-Jakob disease in the squirrel monkey (Saimiri sciureus).

scientific article published on February 2007

Continued use of poliovirus after eradication: hyper-attenuated strains as a safe alternative for release testing of human immunoglobulins

scientific article published on 01 December 2018

Continuous Solvent/Detergent Virus Inactivation Using a Packed-Bed Reactor

scientific article published on 23 April 2019

Contribution to safety of immunoglobulin and albumin from virus partitioning and inactivation by cold ethanol fractionation: a data collection from Plasma Protein Therapeutics Association member companies

scientific article

Cytomegalovirus neutralization by hyperimmune and standard intravenous immunoglobulin preparations

scientific article published on August 2011

Emerging trends in plasma-free manufacturing of recombinant protein therapeutics expressed in mammalian cells

scientific article published on February 2009

Evaluation of different serological diagnostic methods for tick-borne encephalitis virus: enzyme-linked immunosorbent, immunofluorescence, and neutralization assay

scientific article published on 20 December 2013

H5N1 whole-virus vaccine induces neutralizing antibodies in humans which are protective in a mouse passive transfer model

scientific article (publication date: 2011)

Hepatitis A virus antibodies in immunoglobulin preparations

scientific article published on 04 December 2009

Hepatitis E virus and the safety of plasma products: investigations into the reduction capacity of manufacturing processes

scientific article

Human IgG Subclasses: In Vitro Neutralization of and In Vivo Protection against West Nile Virus ⬇️

scientific article published on December 1, 2010

Hyperimmune intravenous immunoglobulin containing high titers of pandemic H1N1 hemagglutinin and neuraminidase antibodies provides dose-dependent protection against lethal virus challenge in SCID mice

scientific article

Immunoglobulins and virus antibody titers: of past needs, current requirements, and future options

scientific article published on 01 December 2018

Impact of vCJD on blood supply

scientific article published on 21 February 2007

In reply

scientific article published on 01 September 2013

Inactivation of hepatitis A variants during heat treatment (pasteurization) of human serum albumin ⬇️

scientific article published on July 25, 2011

Inactivation of parvovirus B19 during STIM-4 vapor heat treatment of three coagulation factor concentrates

scientific article

Influence of Extraction Protocol on Physical Properties of Parvovirus B19 DNA ⬇️

scientific article published on October 13, 2010

MVA vectors expressing conserved influenza proteins protect mice against lethal challenge with H5N1, H9N2 and H7N1 viruses

scientific article

Measles Virus Neutralizing Antibodies in Intravenous Immunoglobulins:is an Increase by Re-Vaccination of Plasma Donors possible?

scientific article published on 18 August 2017

Measles virus neutralizing antibodies in immunoglobulin lots produced from plasma collected in Europe or the United States

scientific article published on 03 May 2019

Measuring the effectiveness of gaseous virus disinfectants

scientific article published on 7 August 2015

Meeting Report: 2013 PDA Virus & TSE Safety Forum

scientific article published on May 2014

Meeting Report: 2015 PDA Virus & TSE Safety Forum

scientific article

Meeting Report: PDA Virus and TSE Safety Forum.

scientific article published on March 2013

Meeting report--workshop on virus removal by filtration: trends and new developments.

scientific article published in March 2013

Meeting report-workshop on spike characterizations and virus removal by filtration: trends and new developments

scientific article

Molecular Basis of the Divergent Immunogenicity of Two Pediatric Tick-Borne Encephalitis Virus Vaccines

scientific article published on 9 December 2015

Nanofiltration as a robust method contributing to viral safety of plasma-derived therapeutics: 20 years' experience of the plasma protein manufacturers

scientific article published on 19 August 2020

Neuraminidase-Inhibiting Antibody Response to H5N1 Virus Vaccination in Chronically Ill and Immunocompromised Patients

scientific article published on 25 August 2014

Neutralization of different echovirus serotypes by individual lots of intravenous immunoglobulin ⬇️

scientific article published on 01 February 2011

Neutralization of human parvovirus B19 by plasma and intravenous immunoglobulins

scientific article

No SARS-CoV-2 neutralization by intravenous immunoglobulins produced from plasma collected before the 2020 pandemic

scientific article published on 17 September 2020

Parallel evaluation of broad virus detection methods

scientific article published on November 2014

Pre-Clinical Efficacy and Safety of Experimental Vaccines Based on Non-Replicating Vaccinia Vectors against Yellow Fever ⬇️

scientific article published on September 9, 2011

Pre-vaccination immunity and immune responses to a cell culture-derived whole-virus H1N1 vaccine are similar to a seasonal influenza vaccine.

scientific article

Preparation of commercial quantities of a hyperimmune human intravenous immunoglobulin preparation against an emerging infectious disease: the example of pandemic H1N1 influenza ⬇️

scientific article published on October 7, 2011

Prion removal capacity of plasma protein manufacturing processes: a data collection from PPTA member companies

scientific article

Proceedings of the 2017 Viral Clearance Symposium Session 5: Facility Risk Mitigation

scientific article published on 20 July 2018

Proceedings of the 2017 Viral Clearance Symposium, Session 2.1: DSP Unit Operations-Virus Filtration/Inactivation

scientific article published on 20 July 2018

Proceedings of the 2017 Viral Clearance Symposium, Session 2.2: DSP Unit Operations-Purification Unit Operations

scientific article published on 20 July 2018

Quantification of SARS-CoV-2 antibodies with eight commercially available immunoassays

scientific article published on 06 July 2020

Quantitative comparison of the cross-protection induced by tick-borne encephalitis virus vaccines based on European and Far Eastern virus subtypes

scientific article published on 14 December 2011

Reduction of spiked porcine circovirus during the manufacture of a Vero cell-derived vaccine.

scientific article

Reflections on the emergence of chikungunya virus in the United States: time to revisit a successful paradigm for the safety of blood-derived therapies.

scientific article published in January 2015

Removal of small nonenveloped viruses by antibody-enhanced nanofiltration during the manufacture of plasma derivatives

scientific article published on 01 July 2006

Robustness of solvent/detergent treatment of plasma derivatives: a data collection from Plasma Protein Therapeutics Association member companies

scientific article

SARS-CoV-2 and the safety margins of cell-based biological medicinal products

scientific article published on 29 August 2020

Safety and immunogenicity of a vero cell culture-derived whole-virus influenza A(H5N1) vaccine in a pediatric population.

scientific article

Safety and immunogenicity of an inactivated whole virus Vero cell-derived Ross River virus vaccine: a randomized trial

scientific article published on 12 October 2011

Secondary structure of DNA released from purified capsids of human parvovirus B19 under moderate denaturing conditions

scientific article published on 29 March 2019

Selection of recombinant MVA by rescue of the essential D4R gene ⬇️

scientific article published on December 12, 2011

Synthesis of 'Nereid', a new phenol-free detergent to replace Triton X-100 in virus inactivation

scientific article published on 04 December 2020

TT virus does not contaminate first-generation recombinant factor VIII concentrate

scientific article published in September 2002

The evolution of down-scale virus filtration equipment for virus clearance studies

scientific article

Tick-Borne Encephalitis Virus-Neutralizing Antibodies in Different Immunoglobulin Preparations ⬇️

scientific article published on February 29, 2012

Tick-borne encephalitis virus vaccine as additional alternative neoantigen for the clinical immunologist's toolbox.

scientific article published on 28 December 2012

Treatment of Ebola virus infection with antibodies from reconvalescent donors

scientific article

Truly continuous low pH viral inactivation for biopharmaceutical process integration

scientific article published on 04 February 2020

Vectors Based on Modified Vaccinia Ankara Expressing Influenza H5N1 Hemagglutinin Induce Substantial Cross-Clade Protective Immunity ⬇️

scientific article (publication date: 24 January 2011)

Viral contamination in biologic manufacture and implications for emerging therapies

scientific article published on 27 April 2020

Virus & TSE safety forum 2008.

scientific article published on 30 July 2009

Virus Filtration and Flow Variation: An Approach To Evaluate Any Potential Impact on Virus Retention

scientific article

Virus disinfection for biotechnology applications: Different effectiveness on surface versus in suspension

scientific article published on 11 February 2020

Virus inactivation during the freeze-drying processes as used for the manufacture of plasma-derived medicinal products

scientific article published on 19 May 2009

Virus susceptibility of Chinese hamster ovary (CHO) cells and detection of viral contaminations by adventitious agent testing

scientific article published in July 2010

West Nile virus and the safety of plasma derivatives: verification of high safety margins, and the validity of predictions based on model virus data

scientific article published in August 2003

West Nile virus infection in plasma of blood and plasma donors, United States

scientific article published on October 2009

West Nile virus neutralization by US plasma-derived immunoglobulin products

scientific article

Zika virus is not thermostable: very effective virus inactivation during heat treatment (pasteurization) of human serum albumin

scientific article (publication date: 17 December 2016)

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