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List of works by Theo M Bestebroer

A family-wide RT-PCR assay for detection of paramyxoviruses and application to a large-scale surveillance study

scientific article (publication date: 2012)

A previously undescribed coronavirus associated with respiratory disease in humans

scholarly article

A30 Avian influenza viruses in wild birds: Virus evolution in a multi-host ecosystem

Adaptation of pandemic H2N2 influenza A viruses in humans.

scientific article

Adenosine deaminase acts as a natural antagonist for dipeptidyl peptidase 4-mediated entry of the Middle East respiratory syndrome coronavirus

scientific article published on 20 November 2013

Airborne transmission of influenza A/H5N1 virus between ferrets

scientific article (publication date: 22 June 2012)

An orthopoxvirus-based vaccine reduces virus excretion after MERS-CoV infection in dromedary camels

scientific article published on 17 December 2015

Analysis of the genomic sequence of a human metapneumovirus

scientific article

Antigenic variation of clade 2.1 H5N1 virus is determined by a few amino acid substitutions immediately adjacent to the receptor binding site

scientific article

Asymptomatic Middle East respiratory syndrome coronavirus infection in rabbits

scientific article published on 25 March 2015

Author Correction: Rapid SARS-CoV-2 whole-genome sequencing and analysis for informed public health decision-making in the Netherlands

scientific article published on 20 October 2020

Avian Influenza A(H10N7) virus-associated mass deaths among harbor seals

scientific article published on April 2015

Avian Influenza Viruses in Wild Birds: Virus Evolution in a Multihost Ecosystem

scholarly article by Divya Venkatesh published in August 2018

COVID-19 in health-care workers in three hospitals in the south of the Netherlands: a cross-sectional study

scientific article published on 02 July 2020

COVID-19 in healthcare workers in three hospitals in the South of the Netherlands, March 2020

scientific article published on 01 May 2020

Case of seasonal reassortant A(H1N2) influenza virus infection, the Netherlands, March 2018

scientific article published on 01 April 2018

Characterization of a novel influenza A virus hemagglutinin subtype (H16) obtained from black-headed gulls

scientific article

Co-circulation of genetically distinct highly pathogenic avian influenza A clade 2.3.4.4 (H5N6) viruses in wild waterfowl and poultry in Europe and East Asia, 2017-18

article

Comparative Pathogenesis Of COVID-19, MERS And SARS In A Non-Human Primate Model

scientific article (preprint)

Comparative pathogenesis of COVID-19, MERS, and SARS in a nonhuman primate model

scientific article published on 17 April 2020

Comparison of sequencing methods and data processing pipelines for whole genome sequencing and minority single nucleotide variant (mSNV) analysis during an influenza A/H5N8 outbreak

scientific article published on 20 February 2020

Correction for Joseph et al., Adaptation of pandemic H2N2 influenza A viruses in humans

scientific article published on April 2015

Correction for Koel et al., Antigenic Variation of Clade 2.1 H5N1 Virus Is Determined by a Few Amino Acid Substitutions Immediately Adjacent to the Receptor Binding Site.

scientific article published on 12 August 2014

Efficient generation and growth of influenza virus A/PR/8/34 from eight cDNA fragments

scientific article published on July 2004

Epistatic interactions can moderate the antigenic effect of substitutions in haemagglutinin of influenza H3N2 virus

scientific article published on 24 April 2019

Genetic evolution of the neuraminidase of influenza A (H3N2) viruses from 1968 to 2009 and its correspondence to haemagglutinin evolution

scientific article published on 20 June 2012

Genomewide analysis of reassortment and evolution of human influenza A(H3N2) viruses circulating between 1968 and 2011

scientific article

Genomic characterization of a newly discovered coronavirus associated with acute respiratory distress syndrome in humans

scientific article

H1N1pdm09 Influenza Virus and Its Descendants Lack Extra-epitopic Amino Acid Residues Associated With Reduced Recognition by M158-66-Specific CD8+ T Cells

scholarly article by Carolien E van de Sandt et al published 13 July 2018 in Journal of Infectious Diseases

Hemagglutinin Traits Determine Transmission of Avian A/H10N7 Influenza Virus between Mammals

scientific article published on 01 October 2020

Highly pathogenic avian influenza (H7N7): vaccination of zoo birds and transmission to non-poultry species

scientific article published on 19 September 2005

Human Clade 2.3.4.4 A/H5N6 Influenza Virus Lacks Mammalian Adaptation Markers and Does Not Transmit via the Airborne Route between Ferrets.

scientific article published on 3 January 2018

Human coronavirus EMC does not require the SARS-coronavirus receptor and maintains broad replicative capability in mammalian cell lines

scientific article

Identification of amino acid substitutions supporting antigenic change of influenza A(H1N1)pdm09 viruses.

scientific article

Identification, characterization, and natural selection of mutations driving airborne transmission of A/H5N1 virus

scientific article

Induction of influenza (H5N8) antibodies by modified vaccinia virus Ankara H5N1 vaccine

scientific article published on June 2015

Influenza A (H10N7) Virus Causes Respiratory Tract Disease in Harbor Seals and Ferrets

scientific article published on 22 July 2016

Influenza A virus (H5N1) infection in cats causes systemic disease with potential novel routes of virus spread within and between hosts.

scientific article

Influenza A virus evolution and spatio-temporal dynamics in Eurasian wild birds: a phylogenetic and phylogeographical study of whole-genome sequence data

scientific article

Influenza A viruses are transmitted via the air from the nasal respiratory epithelium of ferrets

scientific article published on 07 February 2020

Insertion of a multibasic cleavage motif into the hemagglutinin of a low-pathogenic avian influenza H6N1 virus induces a highly pathogenic phenotype

scientific article

Insertion of a multibasic cleavage site in the haemagglutinin of human influenza H3N2 virus does not increase pathogenicity in ferrets

scientific article

Introduction of virulence markers in PB2 of pandemic swine-origin influenza virus does not result in enhanced virulence or transmission.

scientific article

Isolation of a novel coronavirus from a man with pneumonia in Saudi Arabia

scientific article (publication date: 8 November 2012)

Lack of Middle East Respiratory Syndrome Coronavirus Transmission in Rabbits

article

Lack of virological and serological evidence for continued circulation of highly pathogenic avian influenza H5N8 virus in wild birds in the Netherlands, 14 November 2014 to 31 January 2016.

scientific article published on September 2016

Limited airborne transmission of H7N9 influenza A virus between ferrets

scientific article published on 07 August 2013

Local amplification of highly pathogenic avian influenza H5N8 viruses in wild birds in the Netherlands, 2016 to 2017.

scientific article published in January 2018

Low Virulence and Lack of Airborne Transmission of the Dutch Highly Pathogenic Avian Influenza Virus H5N8 in Ferrets.

scientific article

MERS-coronavirus replication induces severe in vitro cytopathology and is strongly inhibited by cyclosporin A or interferon-α treatment

scientific article

Migratory birds reinforce local circulation of avian influenza viruses

scientific article

Multiple Natural Substitutions in Avian Influenza A Virus PB2 Facilitate Efficient Replication in Human Cells

scientific article

Mutations Driving Airborne Transmission of A/H5N1 Virus in Mammals Cause Substantial Attenuation in Chickens only when combined

scientific article published on 03 August 2017

Mutations, drift, and the influenza archipelago.

scientific article published in December 2004

Optimisations and Challenges Involved in the Creation of Various Bioluminescent and Fluorescent Influenza A Virus Strains for In Vitro and In Vivo Applications

scientific article

Optimization of an enzyme-linked lectin assay suitable for rapid antigenic characterization of the neuraminidase of human influenza A(H3N2) viruses

scientific article

PCR-based influenza A virus surveillance in European birds

Pathogenesis and transmission of swine-origin 2009 A(H1N1) influenza virus in ferrets.

scientific article

Phylogeny of Spanish swine influenza viruses isolated from respiratory disease outbreaks and evolution of swine influenza virus within an endemically infected farm.

scientific article

Possible increased pathogenicity of pandemic (H1N1) 2009 influenza virus upon reassortment

scientific article

Practical considerations for high-throughput influenza A virus surveillance studies of wild birds by use of molecular diagnostic tests

scientific article published on 24 December 2008

Protection of mice against lethal infection with highly pathogenic H7N7 influenza A virus by using a recombinant low-pathogenicity vaccine strain

scientific article

Rapid SARS-CoV-2 whole genome sequencing for informed public health decision making in the Netherlands

scientific article published on 26 April 2020

Rapid SARS-CoV-2 whole-genome sequencing and analysis for informed public health decision-making in the Netherlands

scientific article published on 16 July 2020

Rapid sequencing of the non-coding regions of influenza A virus

scientific article published on 23 October 2006

Reassortment between Avian H5N1 and human influenza viruses is mainly restricted to the matrix and neuraminidase gene segments

scientific article

Recurring influenza B virus infections in seals

scientific article published in March 2013

SARS-CoV-2 is transmitted via contact and via the air between ferrets

scientific article published on 18 April 2020

SARS-CoV-2 is transmitted via contact and via the air between ferrets

scientific article published on 08 July 2020

Screening of an FDA-approved compound library identifies four small-molecule inhibitors of Middle East respiratory syndrome coronavirus replication in cell culture

scientific article

Serological evidence for non-lethal exposures of Mongolian wild birds to highly pathogenic avian influenza H5N1 virus

scientific article

Severe acute respiratory infection caused by swine influenza virus in a child necessitating extracorporeal membrane oxygenation (ECMO), the Netherlands, October 2016.

scientific article

Severity of pneumonia due to new H1N1 influenza virus in ferrets is intermediate between that due to seasonal H1N1 virus and highly pathogenic avian influenza H5N1 virus.

scientific article

Spatiotemporal Analysis of the Genetic Diversity of Seal Influenza A(H10N7) Virus, Northwestern Europe

scientific article published on 27 January 2016

Substitutions near the receptor binding site determine major antigenic change during influenza virus evolution

scientific article

Swine influenza virus infection dynamics in two pig farms; results of a longitudinal assessment.

scientific article published on 27 March 2012

The multibasic cleavage site in H5N1 virus is critical for systemic spread along the olfactory and hematogenous routes in ferrets

scientific article published on 25 January 2012

Use of GFP-expressing influenza viruses for the detection of influenza virus A/H5N1 neutralizing antibodies

scientific article published on 9 March 2011

Vaccination against highly pathogenic avian influenza H5N1 virus in zoos using an adjuvanted inactivated H5N2 vaccine

scientific article

Viral Factors Important for Efficient Replication of Influenza A Viruses in Cells of the Central Nervous System.

scientific article published on 15 May 2019

Virulence-associated substitution D222G in the hemagglutinin of 2009 pandemic influenza A(H1N1) virus affects receptor binding

scientific article

Wild ducks as long-distance vectors of highly pathogenic avian influenza virus (H5N1)

scientific article published on April 2008

Wild ducks excrete highly pathogenic avian influenza virus H5N8 (2014-2015) without clinical or pathological evidence of disease

scientific article