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List of works by Linda S Wyatt

A conserved poxvirus NlpC/P60 superfamily protein contributes to vaccinia virus virulence in mice but not to replication in cell culture

scientific article published on 20 February 2008

A trimeric HIV-1 envelope gp120 immunogen induces potent and broad anti-V1V2 loop antibodies against HIV-1 in rabbits and rhesus macaques

scientific article

Antibody profiling by proteome microarray reveals the immunogenicity of the attenuated smallpox vaccine modified vaccinia virus ankara is comparable to that of Dryvax

scientific article

Attenuation and immunogenicity of host-range extended modified vaccinia virus Ankara recombinants

scientific article published on 06 August 2013

Comparative analysis of the magnitude, quality, phenotype, and protective capacity of simian immunodeficiency virus gag-specific CD8+ T cells following human-, simian-, and chimpanzee-derived recombinant adenoviral vector immunization

scientific article published on 6 February 2013

Comparative immunogenicity in rhesus monkeys of multi-protein HIV-1 (CRF02_AG) DNA/MVA vaccines expressing mature and immature VLPs

scientific article published on September 2005

Comparison of vaccine strategies using recombinant env-gag-pol MVA with or without an oligomeric Env protein boost in the SHIV rhesus macaque model

scientific article

Control of a mucosal challenge and prevention of AIDS by a multiprotein DNA/MVA vaccine

scientific article

Correlation of immunogenicities and in vitro expression levels of recombinant modified vaccinia virus Ankara HIV vaccines

scientific article

Critical role for Env as well as Gag-Pol in control of a simian-human immunodeficiency virus 89.6P challenge by a DNA prime/recombinant modified vaccinia virus Ankara vaccine

scientific article

DNA Vaccine-Induced Long-Lasting Cytotoxic T Cells Targeting Conserved Elements of Human Immunodeficiency Virus Gag Are Boosted Upon DNA or Recombinant Modified Vaccinia Ankara Vaccination

scholarly article by Xintao Hu published in September 2018

DNA/MVA HIV-1/AIDS vaccine elicits long-lived vaccinia virus-specific immunity and confers protection against a lethal monkeypox challenge

scientific article

DNA/MVA vaccine for HIV type 1: effects of codon-optimization and the expression of aggregates or virus-like particles on the immunogenicity of the DNA prime

scientific article

Different patterns of immune responses but similar control of a simian-human immunodeficiency virus 89.6P mucosal challenge by modified vaccinia virus Ankara (MVA) and DNA/MVA vaccines.

scientific article

Dose-response studies for the elicitation of CD8 T cells by a DNA vaccine, used alone or as the prime for a modified vaccinia Ankara boost

scientific article published on 9 June 2006

Elicitation of simian immunodeficiency virus-specific cytotoxic T lymphocytes in mucosal compartments of rhesus monkeys by systemic vaccination

scientific article

Elucidating and minimizing the loss by recombinant vaccinia virus of human immunodeficiency virus gene expression resulting from spontaneous mutations and positive selection

scientific article published on 06 May 2009

Engineering the vaccinia virus L1 protein for increased neutralizing antibody response after DNA immunization

scientific article published on 03 March 2009

Enhanced cell surface expression, immunogenicity and genetic stability resulting from a spontaneous truncation of HIV Env expressed by a recombinant MVA.

scientific article published on 28 November 2007

GM-CSF DNA: an adjuvant for higher avidity IgG, rectal IgA, and increased protection against the acute phase of a SHIV-89.6P challenge by a DNA/MVA immunodeficiency virus vaccine

scientific article

Generation of Recombinant Vaccinia Viruses

scientific article

Generation of Recombinant Vaccinia Viruses

Generation of Recombinant Vaccinia Viruses.

scientific article published on 5 January 2017

Gp120-alum boosting of a Gag-Pol-Env DNA/MVA AIDS vaccine: poorer control of a pathogenic viral challenge

article

HIV-1 DNA/MVA vaccination reduces the per exposure probability of infection during repeated mucosal SHIV challenges

article

HIV-1 gp120 and Modified Vaccinia Virus Ankara (MVA) gp140 Boost Immunogens Increase Immunogenicity of a DNA/MVA HIV-1 Vaccine

scientific article published on 11 October 2017

HIV-1 vaccination by needle-free oral injection induces strong mucosal immunity and protects against SHIV challenge

article

High Doses of GM-CSF Inhibit Antibody Responses in Rectal Secretions and Diminish Modified Vaccinia Ankara/Simian Immunodeficiency Virus Vaccine Protection in TRIM5α-Restrictive Macaques.

scientific article published on 28 September 2016

Highly attenuated smallpox vaccine protects mice with and without immune deficiencies against pathogenic vaccinia virus challenge

scholarly article

Identification of Poxvirus Genome Uncoating and DNA Replication Factors with Mutually Redundant Roles

scientific article published on 17 January 2018

Immunogenicity in macaques of the clinical product for a clade B DNA/MVA HIV vaccine: elicitation of IFN-gamma, IL-2, and TNF-alpha coproducing CD4 and CD8 T cells

scientific article published in December 2007

Immunogenicity of a highly attenuated MVA smallpox vaccine and protection against monkeypox

scientific article published on March 2004

Multiprotein HIV type 1 clade B DNA and MVA vaccines: construction, expression, and immunogenicity in rodents of the MVA component

scientific article published in June 2004

Multiprotein HIV type 1 clade B DNA/MVA vaccine: construction, safety, and immunogenicity in Macaques

scientific article

Novel Modified Vaccinia Virus Ankara Vector Expressing Anti-apoptotic Gene B13R Delays Apoptosis and Enhances Humoral Responses

scientific article published on 19 February 2019

Novel Nonreplicating Vaccinia Virus Vector Enhances Expression of Heterologous Genes and Suppresses Synthesis of Endogenous Viral Proteins

scientific article

Overcoming immunity to a viral vaccine by DNA priming before vector boosting

scientific article

Phase 1 safety and immunogenicity testing of DNA and recombinant modified vaccinia Ankara vaccines expressing HIV-1 virus-like particles

scientific article

Poxvirus decapping enzymes enhance virulence by preventing the accumulation of dsRNA and the induction of innate antiviral responses

scientific article

Preclinical studies of human immunodeficiency virus/AIDS vaccines: inverse correlation between avidity of anti-Env antibodies and peak postchallenge viremia.

scientific article

Preparation of Cell Cultures and Vaccinia Virus Stocks

scientific article

Preparation of Cell Cultures and Vaccinia Virus Stocks

scientific article published on 01 August 2017

Preparation of Cell Cultures and Vaccinia Virus Stocks

scientific article published on 05 January 2017

Prior vaccination increases the epitopic breadth of the cytotoxic T-lymphocyte response that evolves in rhesus monkeys following a simian-human immunodeficiency virus infection

scientific article

RNA Polymerase Mutations Selected during Experimental Evolution Enhance Replication of a Hybrid Vaccinia Virus with an Intermediate Transcription Factor Subunit Replaced by the Myxoma Virus Ortholog

scholarly article by Carey A Stuart published in October 2018

Rapid protection in a monkeypox model by a single injection of a replication-deficient vaccinia virus

scholarly article

Recombinant modified vaccinia virus Ankara provides durable protection against disease caused by an immunodeficiency virus as well as long-term immunity to an orthopoxvirus in a non-human primate

scientific article

SPI-1 is a missing host-range factor required for replication of the attenuated modified vaccinia Ankara (MVA) vaccine vector in human cells

scientific article published on 30 May 2019

Shared modes of protection against poxvirus infection by attenuated and conventional smallpox vaccine viruses

scientific article

Signature for long-term vaccine-mediated control of a Simian and human immunodeficiency virus 89.6P challenge: stable low-breadth and low-frequency T-cell response capable of coproducing gamma interferon and interleukin-2.

scientific article

Studies in macaques on cross-clade T cell responses elicited by a DNA/MVA AIDS vaccine, better conservation of CD8 than CD4 T cell responses.

scientific article

Studies on GM-CSF DNA as an adjuvant for neutralizing Ab elicited by a DNA/MVA immunodeficiency virus vaccine

scientific article published on 5 June 2006

Studies on in vitro expression and in vivo immunogenicity of a recombinant MVA HIV vaccine

scientific article published on 19 January 2006

T cell responses to respiratory syncytial virus fusion and attachment proteins in human peripheral blood mononuclear cells

scientific article published in January 2006

The D10 decapping enzyme of vaccinia virus contributes to decay of cellular and viral mRNAs and to virulence in mice

scientific article published on 23 October 2013

The neutralizing antibody response to the vaccinia virus A28 protein is specifically enhanced by its association with the H2 protein

scientific article

Vaccination of infant macaques with a recombinant modified vaccinia virus Ankara expressing the respiratory syncytial virus F and G genes does not predispose for immunopathology

scientific article published in February 2004

Zinc-finger antiviral protein (ZAP) is a restriction factor for replication of modified vaccinia virus Ankara (MVA) in human cells

scientific article published on 31 August 2020

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