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List of works by Suryaprakash Sambhara

17β-Estradiol restores antibody responses to an influenza vaccine in a postmenopausal mouse model

scientific article published on 22 February 2011

5'PPP-RNA induced RIG-I activation inhibits drug-resistant avian H5N1 as well as 1918 and 2009 pandemic influenza virus replication

scientific article

A Bovine Adenoviral Vector-Based H5N1 Influenza -Vaccine Provides Enhanced Immunogenicity and Protection at a Significantly Low Dose

A Dual-Functioning 5'-PPP-NS1shRNA that Activates a RIG-I Antiviral Pathway and Suppresses Influenza NS1

scientific article published on 31 January 2020

A Newly Emerged Swine-Origin Influenza A(H3N2) Variant Dampens Host Antiviral Immunity but Induces Potent Inflammasome Activation.

scientific article

A broadly protective vaccine against globally dispersed clade 1 and clade 2 H5N1 influenza viruses.

scientific article

A distal regulatory region is required for constitutive and IFN-beta-induced expression of murine TLR9 gene.

scientific article published on December 2005

A highly immunogenic vaccine against A/H7N9 influenza virus

scientific article

Activation of the RIG-I pathway during influenza vaccination enhances the germinal center reaction, promotes T follicular helper cell induction, and provides a dose-sparing effect and protective immunity.

scientific article

Adenoviral Vector-Based Vaccine Platforms for Developing the Next Generation of Influenza Vaccines

scientific article published on 01 October 2020

Adenoviral vector expressing murine β-defensin 2 enhances immunogenicity of an adenoviral vector based H5N1 influenza vaccine in aged mice ⬇️

scientific article published on July 23, 2013

Adenovirus vector-based multi-epitope vaccine provides partial protection against H5, H7, and H9 avian influenza viruses

scientific article published on 12 October 2017

Age, serum 25-hydroxyvitamin D and vitamin D receptor (VDR) expression and function in peripheral blood mononuclear cells

scientific article published on 17 May 2016

An Adjuvanted A(H5N1) Subvirion Vaccine Elicits Virus-Specific Antibody Response and Improves Protection Against Lethal Influenza Viral Challenge in Mouse Model of Protein Energy Malnutrition

scientific article published on September 2017

An ELISA-based method for detection of rabies virus nucleoprotein-specific antibodies in human antemortem samples

scientific article published in PLoS ONE

An oil-in-water nanoemulsion enhances immunogenicity of H5N1 vaccine in mice

scientific article

Antiviral defense: RIG-Ing the immune system to STING.

scientific article published on 10 February 2009

Avian influenza vaccines: what's all the flap?

article

Beta-defensin 2 enhances immunogenicity and protection of an adenovirus-based H5N1 influenza vaccine at an early time

scientific article

Breaking the immunogenicity barrier of bird flu vaccines

article

Broadly protective adenovirus-based multivalent vaccines against highly pathogenic avian influenza viruses for pandemic preparedness

scientific article

Cell-Mediated Immunity Against Antigenically Drifted Influenza A(H3N2) Viruses in Children During a Vaccine Mismatch Season

scientific article published on 17 August 2016

Challenges for vaccination in the elderly.

scientific article published on 11 December 2007

Comparative Immunogenicity of Several Enhanced Influenza Vaccine Options for Older Adults: A Randomized, Controlled Trial

scientific article published on 12 December 2019

Conserved Oligomeric Golgi (COG) Complex Proteins Facilitate Orthopoxvirus Entry, Fusion and Spread

scientific article published on 30 June 2020

Correction: Critical Role of an Antiviral Stress Granule Containing RIG-I and PKR in Viral Detection and Innate Immunity.

scientific article published on 31 October 2012

Correction: Critical Role of an Antiviral Stress Granule Containing RIG-I and PKR in Viral Detection and Innate Immunity.

scientific article published on 18 April 2013

Critical role of RIG-I and MDA5 in early and late stages of Tulane virus infection

scientific article

Critical role of an antiviral stress granule containing RIG-I and PKR in viral detection and innate immunity

scientific article

Cutting edge: impaired Toll-like receptor expression and function in aging

scientific article published on 01 November 2002

Cytokine and chemokine profiles in lung tissues from fatal cases of 2009 pandemic influenza A (H1N1): role of the host immune response in pathogenesis.

scientific article

Cytoplasmic nucleic acid sensors in antiviral immunity

scientific article published on 06 August 2009

DNA vaccine expressing conserved influenza virus proteins protective against H5N1 challenge infection in mice.

scientific article

Development of adenoviral-vector-based pandemic influenza vaccine against antigenically distinct human H5N1 strains in mice.

scientific article

Discovery of Retro-1 Analogs Exhibiting Enhanced Anti-vaccinia Virus Activity

scientific article published on 23 April 2020

Early control of H5N1 influenza virus replication by the type I interferon response in mice.

scientific article published on 18 March 2009

Egg-independent vaccine strategies for highly pathogenic H5N1 influenza viruses.

scientific article

Gold nanorod delivery of an ssRNA immune activator inhibits pandemic H1N1 influenza viral replication

scientific article

H5N1 Avian influenza: preventive and therapeutic strategies against a pandemic.

scientific article

H5N1 vaccine hits the target, but not the bull's eye

scientific article published on 01 August 2007

High-dose influenza vaccine favors acute plasmablast responses rather than long-term cellular responses

scientific article

Human Heat shock protein 40 (Hsp40/DnaJB1) promotes influenza A virus replication by assisting nuclear import of viral ribonucleoproteins

scientific article

Immunity to influenza: the challenges of protecting an aging population.

scientific article

Immunosenescence and Challenges of Vaccination against Influenza in the Aging Population ⬇️

scientific article published on September 30, 2011

Immunosenescence and influenza vaccine efficacy

scientific article published on January 2009

Impact of Preexisting Adenovirus Vector Immunity on Immunogenicity and Protection Conferred with an Adenovirus-Based H5N1 Influenza Vaccine ⬇️

scientific article published on March 14, 2012

Impaired antigen-induced CD8+ T cell clonal expansion in aging is due to defects in antigen presenting cell function

scientific article published on 01 June 2004

Improving immunogenicity and effectiveness of influenza vaccine in older adults

scientific article

Improving influenza vaccines ⬇️

scientific article published on 01 August 2012

Increased Dietary Salt Intake Does Not Influence Influenza A Virus-Induced Disease Severity in Mice

scientific article published on 18 August 2015

Increased MDSC accumulation and Th2 biased response to influenza A virus infection in the absence of TLR7 in mice

scientific article

Infection of lung epithelial cells with pandemic 2009 A(H1N1) influenza viruses reveals isolate-specific differences in infectivity and host cellular responses

scientific article

Influence of pre-existing hemagglutination inhibition titers against historical influenza strains on antibody response to inactivated trivalent influenza vaccine in adults 50-80 years of age.

scientific article published on 10 March 2014

Influenza A Virus Nucleoprotein Activates the JNK Stress-Signaling Pathway for Viral Replication by Sequestering Host Filamin A Protein

scientific article published on 25 September 2020

Influenza A Virus Nucleoprotein Exploits Hsp40 to Inhibit PKR Activation ⬇️

scientific article published on June 15, 2011

Influenza A viral nucleoprotein interacts with cytoskeleton scaffolding protein α-actinin-4 for viral replication

scientific article

Influenza A virus neuraminidase protein enhances cell survival through interaction with carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6) protein

scientific article published on 6 March 2012

Influenza virus NS1- C/EBPβ gene regulatory complex inhibits RIG-I transcription

scientific article published on 21 February 2020

Influenza virus exploits tunneling nanotubes for cell-to-cell spread

scientific article

Innate immunity in aging: impact on macrophage function

scientific article published in August 2004

Kinetics of antibody response to influenza vaccination in renal transplant recipients

scholarly article by Shivaprakash Gangappa et al published April 2019 in Transplant Immunology

Longevity of adenovirus vector immunity in mice and its implications for vaccine efficacy

scholarly article by Ekramy E Sayedahmed et al published 29 October 2018 in Vaccine

Monkeypox Virus Host Factor Screen Using Haploid Cells Identifies Essential Role of GARP Complex in Extracellular Virus Formation

scientific article

Moving influenza vaccines forward

scientific article published on 01 April 2009

NADPH Oxidase 1 Is Associated with Altered Host Survival and T Cell Phenotypes after Influenza A Virus Infection in Mice

scientific article

NLRC5 interacts with RIG-I to induce a robust antiviral response against influenza virus infection

scientific article

NLRX1 protein attenuates inflammatory responses to infection by interfering with the RIG-I-MAVS and TRAF6-NF-κB signaling pathways

scientific journal article

NS1 protein of influenza A virus inhibits the function of intracytoplasmic pathogen sensor, RIG-I

scientific article

Nasal delivery of H5N1 avian influenza vaccine formulated with GenJet™ or in vivo-jetPEI® induces enhanced serological, cellular and protective immune responses

scientific article published in November 2018

Nasal delivery of Protollin-adjuvanted H5N1 vaccine induces enhanced systemic as well as mucosal immunity in mice

scientific article

Needle-free skin patch delivery of a vaccine for a potentially pandemic influenza virus provides protection against lethal challenge in mice.

scientific article

Non-neutralizing antibodies induced by seasonal influenza vaccine prevent, not exacerbate A(H1N1)pdm09 disease

scientific article

PAMPer and tRIGer: ligand-induced activation of RIG-I.

scientific article published on 14 April 2011

Patients Hospitalized with pH1N1 Influenza in an Academic Community Medical Center ⬇️

scientific article published on June 20, 2011

Preexisting Immunity, More Than Aging, Influences Influenza Vaccine Responses

scientific article

Prior infection with influenza virus but not vaccination leaves a long-term immunological imprint that intensifies the protective efficacy of antigenically drifted vaccine strains

scientific article

Protein energy malnutrition decreases immunity and increases susceptibility to influenza infection in mice

scholarly article by Andrew K Taylor et al published 1 February 2013 in Journal of Infectious Diseases

RIG-I Goes Beyond Naked Recognition ⬇️

scientific article published on March 13, 2013

RIG-I activation inhibits ebolavirus replication

scientific article

RIG-I ligand enhances the immunogenicity of recombinant H7HA protein

scientific article

Rapamycin Does Not Impede Survival or Induction of Antibody Responses to Primary and Heterosubtypic Influenza Infections in Mice

scientific article published on 22 July 2016

Rapid Differentiation of Monocytes into Type I IFN-Producing Myeloid Dendritic Cells as an Antiviral Strategy against Influenza Virus Infection ⬇️

scientific article published on September 1, 2012

Role of host cytokine responses in the pathogenesis of avian H5N1 influenza viruses in mice

scientific article published on 20 December 2006

SARS-CoV-2 RBD Neutralizing Antibody Induction is Enhanced by Particulate Vaccination

scientific article published on 28 October 2020

Seasonal Influenza Vaccination of Children Induces Humoral and Cell-Mediated Immunity Beyond the Current Season: Cross-reactivity With Past and Future Strains

scientific article

Significant impact of sequence variations in the nucleoprotein on CD8 T cell-mediated cross-protection against influenza A virus infections

scientific article (publication date: 2010)

Standard dose intradermal influenza vaccine elicits similar cellular immune responses when compared to intramuscular vaccine in HIV-infected or uninfected men

article

Strategies to alleviate original antigenic sin responses to influenza viruses ⬇️

scientific article published on August 6, 2012

TLR7 recognition is dispensable for influenza virus A infection but important for the induction of hemagglutinin-specific antibodies in response to the 2009 pandemic split vaccine in mice

scientific article

The 3' untranslated regions of influenza genomic sequences are 5'PPP-independent ligands for RIG-I

scientific article

The innate immune system: a repository for future drugs?

scientific article published on 01 February 2007

Vaccine approaches conferring cross-protection against influenza viruses

scientific article published on 19 September 2017

Vaccines against epidemic and pandemic influenza

article

Vaccines against influenza A (H5N1): evidence of progress

scientific article published on 01 September 2008

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