List of works - Sander Tans

A graph-based algorithm for the multi-objective optimization of gene regulatory networks

scientific article published in 2018

A polypeptide-DNA hybrid with selective linking capability applied to single molecule nano-mechanical measurements using optical tweezers

scientific article published in 2013

Alternative modes of client binding enable functional plasticity of Hsp70.

scientific article

An improved Escherichia coli strain to host gene regulatory networks involving both the AraC and LacI inducible transcription factors

scientific article published on 2 January 2014

Apical constriction is necessary for crypt formation in small intestinal organoids

scientific article published on 23 March 2019

Bacterial coexistence driven by motility and spatial competition

scientific article published on 19 February 2020

Breaking evolutionary constraint with a tradeoff ratchet

scientific article

Calcium modulates force sensing by the von Willebrand factor A2 domain

scientific article

Chaperone action at the single-molecule level.

scientific article

Circuit topology of proteins and nucleic acids.

scientific article

Circuit topology of self-interacting chains: implications for folding and unfolding dynamics

article

Deciphering Metabolic Heterogeneity by Single-Cell Analysis

scientific article published on 08 October 2019

Designing disorder: Tales of the unexpected tails

scientific article published on January 2013

Direct observation of chaperone-induced changes in a protein folding pathway

scientific article published in November 2007

Direct observation of type 1 fimbrial switching

scientific article

Electron–electron correlations in carbon nanotubes

scientific article published in Nature

Empirical fitness landscapes reveal accessible evolutionary paths

scientific article

Environmental dependence of genetic constraint

scientific article

Evolutionary Potential of a Duplicated Repressor-Operator Pair: Simulating Pathways using Mutation Data

scientific article published on 13 April 2006

Evolutionary constraints in variable environments, from proteins to networks

scientific article published on 26 April 2014

Evolutionary potential of a duplicated repressor-operator pair: simulating pathways using mutation data

scientific article

Fast and efficient generation of knock-in human organoids using homology-independent CRISPR-Cas9 precision genome editing

scientific article published on 02 March 2020

Fullerene 'crop circles'

scientific article published in Nature

Generation and filtering of gene expression noise by the bacterial cell cycle

scientific article

Hydrophobic Collapse of Trigger Factor Monomer in Solution ⬇️

scientific article published on April 2, 2013

Individual single-wall carbon nanotubes as quantum wires

scientific article published in Nature

Individuality and universality in the growth-division laws of single E. coli cells. ⬇️

scientific article

Information-theoretic analysis of the directional influence between cellular processes

scientific article published on 9 November 2017

Interactions between nascent proteins translated by adjacent ribosomes drive homomer assembly

scientific article published on 01 January 2021

Internal dynamics of supercoiled DNA molecules

scientific article published on June 2009

Long-term expanding human airway organoids for disease modeling

scientific article published on 14 January 2019

Microfabricated polyacrylamide devices for the controlled culture of growing cells and developing organisms

scientific article

Misfolding of luciferase at the single-molecule level

scientific article published on 14 August 2014

Multiple peaks and reciprocal sign epistasis in an empirically determined genotype-phenotype landscape.

scientific article

Noise reduction by signal combination in Fourier space applied to drift correction in optical tweezers.

scientific article published in November 2011

Non-monotonic dynamics and crosstalk in signaling pathways and their implications for pharmacology

scientific article (publication date: 18 June 2015)

Optimality and evolution of transcriptionally regulated gene expression

scientific article

Optimality in evolution: new insights from synthetic biology.

scientific article published on 16 May 2013

Optimized human intestinal organoid model reveals interleukin-22-dependency of paneth cell formation

scientific article published in 2022

OrganoidTracker: Efficient cell tracking using machine learning and manual error correction

scientific article published on 22 October 2020

Predicting Evolution Using Regulatory Architecture

scientific article published on 04 February 2020

Predicting Evolutionary Constraints by Identifying Conflicting Demands in Regulatory Networks

scientific article published on 11 June 2020

Processive extrusion of polypeptide loops by a Hsp100 disaggregase

scientific article published on 29 January 2020

Protein Folding Mediated by Trigger Factor and Hsp70: New Insights from Single-Molecule Approaches.

scientific article

Protein Tethering for Folding Studies

scientific article

Publisher Correction: Processive extrusion of polypeptide loops by a Hsp100 disaggregase

scientific article published on 01 February 2020

Reciprocal sign epistasis is a necessary condition for multi-peaked fitness landscapes.

scientific article

Reshaping of the conformational search of a protein by the chaperone trigger factor.

scientific article published on 7 July 2013

Revealing evolutionary pathways by fitness landscape reconstruction

scientific article published on July 2009

Room-temperature transistor based on a single carbon nanotube

scientific article

SecA supports a constant rate of preprotein translocation.

scientific article

SecB--a chaperone dedicated to protein translocation.

scientific article published on 19 October 2009

Sign epistasis caused by hierarchy within signalling cascades

scientific article published on 13 April 2018

Single-Cell Analysis of the Dps Response to Oxidative Stress.

scientific article published on 28 March 2016

Single-cell dynamics reveals sustained growth during diauxic shifts

scientific article

Size Laws and Division Ring Dynamics in Filamentous Escherichia coli cells.

scientific article published on 22 February 2018

Small heat shock proteins sequester misfolding proteins in near-native conformation for cellular protection and efficient refolding.

scientific article

Step by Step, Cell by Cell: Quantification of the Bacterial Cell Cycle

scientific article published on 13 January 2017

Stochasticity and homeostasis in the E. coli replication and division cycle.

scientific article published on 16 December 2015

Stochasticity of metabolism and growth at the single-cell level

scientific article

Taming membranes: functional immobilization of biological membranes in hydrogels.

scientific article

The Anti-Aggregation Holdase Hsp33 Promotes the Formation of Folded Protein Structures

scientific article published on 11 November 2019

The Trigger Factor Chaperone Encapsulates and Stabilizes Partial Folds of Substrate Proteins

scientific article published on 29 October 2015

The chaperone toolbox at the single-molecule level: From clamping to confining

scientific article published on 25 March 2017

Tight hydrophobic contacts with the SecB chaperone prevent folding of substrate proteins.

scientific article published in March 2010

Topology of internally constrained polymer chains

scientific article published on 5 July 2017

Topology of polymer chains under nanoscale confinement

scientific article published on 14 August 2017

Tradeoffs and optimality in the evolution of gene regulation.

scientific article published on 28 July 2011

Transcriptional Regulation by Competing Transcription Factor Modules

scientific article published on 24 October 2006

Transcriptional regulation by competing transcription factor modules

scientific article

Trehalose facilitates DNA melting: a single-molecule optical tweezers study.

scientific article

[Random fluctuations, metabolism and growth at the single-cell level].

scientific article published in March 2015

List of works by Sander Tans

A graph-based algorithm for the multi-objective optimization of gene regulatory networks

A polypeptide-DNA hybrid with selective linking capability applied to single molecule nano-mechanical measurements using optical tweezers

Alternative modes of client binding enable functional plasticity of Hsp70.

An improved Escherichia coli strain to host gene regulatory networks involving both the AraC and LacI inducible transcription factors

Apical constriction is necessary for crypt formation in small intestinal organoids

Bacterial coexistence driven by motility and spatial competition

Breaking evolutionary constraint with a tradeoff ratchet

Calcium modulates force sensing by the von Willebrand factor A2 domain

Chaperone action at the single-molecule level.

Circuit topology of proteins and nucleic acids.

Circuit topology of self-interacting chains: implications for folding and unfolding dynamics

Deciphering Metabolic Heterogeneity by Single-Cell Analysis

Designing disorder: Tales of the unexpected tails

Direct observation of chaperone-induced changes in a protein folding pathway

Direct observation of type 1 fimbrial switching

Electron–electron correlations in carbon nanotubes

Empirical fitness landscapes reveal accessible evolutionary paths

Environmental dependence of genetic constraint

Evolutionary Potential of a Duplicated Repressor-Operator Pair: Simulating Pathways using Mutation Data

Evolutionary constraints in variable environments, from proteins to networks

Evolutionary potential of a duplicated repressor-operator pair: simulating pathways using mutation data

Fast and efficient generation of knock-in human organoids using homology-independent CRISPR-Cas9 precision genome editing

Fullerene 'crop circles'

Generation and filtering of gene expression noise by the bacterial cell cycle

Hydrophobic Collapse of Trigger Factor Monomer in Solution ⬇️

Individual single-wall carbon nanotubes as quantum wires

Individuality and universality in the growth-division laws of single E. coli cells. ⬇️

Information-theoretic analysis of the directional influence between cellular processes

Interactions between nascent proteins translated by adjacent ribosomes drive homomer assembly

Internal dynamics of supercoiled DNA molecules

Long-term expanding human airway organoids for disease modeling

Microfabricated polyacrylamide devices for the controlled culture of growing cells and developing organisms

Misfolding of luciferase at the single-molecule level

Multiple peaks and reciprocal sign epistasis in an empirically determined genotype-phenotype landscape.

Noise reduction by signal combination in Fourier space applied to drift correction in optical tweezers.

Non-monotonic dynamics and crosstalk in signaling pathways and their implications for pharmacology

Optimality and evolution of transcriptionally regulated gene expression

Optimality in evolution: new insights from synthetic biology.

Optimized human intestinal organoid model reveals interleukin-22-dependency of paneth cell formation

OrganoidTracker: Efficient cell tracking using machine learning and manual error correction

Predicting Evolution Using Regulatory Architecture

Predicting Evolutionary Constraints by Identifying Conflicting Demands in Regulatory Networks

Processive extrusion of polypeptide loops by a Hsp100 disaggregase

Protein Folding Mediated by Trigger Factor and Hsp70: New Insights from Single-Molecule Approaches.

Protein Tethering for Folding Studies

Publisher Correction: Processive extrusion of polypeptide loops by a Hsp100 disaggregase

Reciprocal sign epistasis is a necessary condition for multi-peaked fitness landscapes.

Reshaping of the conformational search of a protein by the chaperone trigger factor.

Revealing evolutionary pathways by fitness landscape reconstruction

Room-temperature transistor based on a single carbon nanotube

SecA supports a constant rate of preprotein translocation.

SecB--a chaperone dedicated to protein translocation.

Sign epistasis caused by hierarchy within signalling cascades

Single-Cell Analysis of the Dps Response to Oxidative Stress.

Single-cell dynamics reveals sustained growth during diauxic shifts

Size Laws and Division Ring Dynamics in Filamentous Escherichia coli cells.

Small heat shock proteins sequester misfolding proteins in near-native conformation for cellular protection and efficient refolding.

Step by Step, Cell by Cell: Quantification of the Bacterial Cell Cycle

Stochasticity and homeostasis in the E. coli replication and division cycle.

Stochasticity of metabolism and growth at the single-cell level

Taming membranes: functional immobilization of biological membranes in hydrogels.

The Anti-Aggregation Holdase Hsp33 Promotes the Formation of Folded Protein Structures

The Trigger Factor Chaperone Encapsulates and Stabilizes Partial Folds of Substrate Proteins

The chaperone toolbox at the single-molecule level: From clamping to confining

Tight hydrophobic contacts with the SecB chaperone prevent folding of substrate proteins.

Topology of internally constrained polymer chains

Topology of polymer chains under nanoscale confinement

Tradeoffs and optimality in the evolution of gene regulation.

Transcriptional Regulation by Competing Transcription Factor Modules

Transcriptional regulation by competing transcription factor modules

Trehalose facilitates DNA melting: a single-molecule optical tweezers study.

[Random fluctuations, metabolism and growth at the single-cell level].