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List of works by Marvin Sommer

A self-excisable infectious bacterial artificial chromosome clone of varicella-zoster virus allows analysis of the essential tegument protein encoded by ORF9.

scientific article

An Sp1/Sp3 Site in the Downstream Region of Varicella-Zoster Virus (VZV) oriS Influences Origin-Dependent DNA Replication and Flanking Gene Transcription and Is Important for VZV Replication In Vitro and in Human Skin ⬇️

scientific article published on August 29, 2012

An immunoreceptor tyrosine-based inhibition motif in varicella-zoster virus glycoprotein B regulates cell fusion and skin pathogenesis ⬇️

scientific article published on January 15, 2013

Analysis of the functions of glycoproteins E and I and their promoters during VZV replication in vitro and in skin and T-cell xenografts in the SCID mouse model of VZV pathogenesis

scientific article published on January 2010

Analysis of varicella zoster virus attenuation by evaluation of chimeric parent Oka/vaccine Oka recombinant viruses in skin xenografts in the SCIDhu mouse model

scientific article

Cellular and viral factors regulate the varicella-zoster virus gE promoter during viral replication

scientific article

Cellular transcription factor YY1 mediates the varicella-zoster virus (VZV) IE62 transcriptional activation

scientific article published on 12 December 2013

Construction of varicella-zoster virus recombinants from parent Oka cosmids and demonstration that ORF65 protein is dispensable for infection of human skin and T cells in the SCID-hu mouse model

scientific article

Deletion of the first cysteine-rich region of the varicella-zoster virus glycoprotein E ectodomain abolishes the gE and gI interaction and differentially affects cell-cell spread and viral entry

scientific article published on 22 October 2008

Development of recombinant varicella-zoster viruses expressing luciferase fusion proteins for live in vivo imaging in human skin and dorsal root ganglia xenografts

scientific article published on 24 September 2008

Differential requirement for cell fusion and virion formation in the pathogenesis of varicella-zoster virus infection in skin and T cells

scientific article published on December 2004

Differentiation of varicella-zoster virus ORF47 protein kinase and IE62 protein binding domains and their contributions to replication in human skin xenografts in the SCID-hu mouse

scientific article

Disruption of PML nuclear bodies is mediated by ORF61 SUMO-interacting motifs and required for varicella-zoster virus pathogenesis in skin

scientific article

Entrapment of Viral Capsids in Nuclear PML Cages Is an Intrinsic Antiviral Host Defense against Varicella-Zoster Virus ⬇️

scientific article published on February 3, 2011

Essential functions of the unique N-terminal region of the varicella-zoster virus glycoprotein E ectodomain in viral replication and in the pathogenesis of skin infection

scientific article

Functions of Varicella-zoster virus ORF23 capsid protein in viral replication and the pathogenesis of skin infection

scientific article

Functions of the C-terminal domain of varicella-zoster virus glycoprotein E in viral replication in vitro and skin and T-cell tropism in vivo

scientific article

Functions of the ORF9-to-ORF12 gene cluster in varicella-zoster virus replication and in the pathogenesis of skin infection

scientific article published on 09 April 2008

Functions of the unique N-terminal region of glycoprotein E in the pathogenesis of varicella-zoster virus infection

scientific article

Genetic analysis of varicella-zoster virus ORF0 to ORF4 by use of a novel luciferase bacterial artificial chromosome system

scientific article

Glycoprotein I of varicella-zoster virus is required for viral replication in skin and T cells

scientific article

Herpes simplex virus-1 induces expression of a novel MxA isoform that enhances viral replication.

scientific article

Identification and functional characterization of the Varicella zoster virus ORF11 gene product ⬇️

scientific article published on January 26, 2011

Identification of a Hydrophobic Domain in Varicella-Zoster Virus ORF61 Necessary for ORF61 Self-Interaction, Viral Replication, and Skin Pathogenesis ⬇️

scientific article published on January 23, 2013

Mutagenesis of Varicella-Zoster Virus Glycoprotein I (gI) Identifies a Cysteine Residue Critical for gE/gI Heterodimer Formation, gI Structure, and Virulence in Skin Cells ⬇️

scientific article published on February 23, 2011

Mutagenesis of varicella-zoster virus glycoprotein B: putative fusion loop residues are essential for viral replication, and the furin cleavage motif contributes to pathogenesis in skin tissue in vivo

scientific article

Mutational Analysis of Open Reading Frames 62 and 71, Encoding the Varicella-Zoster Virus Immediate-Early Transactivating Protein, IE62, and Effects on Replication In Vitro and in Skin Xenografts in the SCID-hu Mouse In Vivo ⬇️

scientific article published on May 1, 2003

Mutational analysis of the varicella-zoster virus ORF62/63 intergenic region

scientific article

Mutational analysis of varicella-zoster virus (VZV) immediate early protein (IE62) subdomains and their importance in viral replication.

scientific article published on 22 February 2016

ORF11 Protein Interacts with the ORF9 Essential Tegument Protein in Varicella-Zoster Virus Infection ⬇️

scientific article published on February 20, 2013

ORF66 protein kinase function is required for T-cell tropism of varicella-zoster virus in vivo

scientific article

Promoter sequences of varicella-zoster virus glycoprotein I targeted by cellular transactivating factors Sp1 and USF determine virulence in skin and T cells in SCIDhu mice in vivo

scientific article

Regulation of the ORF61 promoter and ORF61 functions in varicella-zoster virus replication and pathogenesis

scientific article published on 20 May 2009

Regulation of the varicella-zoster virus ORF3 promoter by cellular and viral factors ⬇️

scientific article published on March 21, 2013

Requirement of Varicella-Zoster Virus Immediate-Early 4 Protein for Viral Replication ⬇️

scientific article published on November 1, 2003

Role of the varicella-zoster virus gene product encoded by open reading frame 35 in viral replication in vitro and in differentiated human skin and T cells in vivo

scientific article

Structure–function analysis of varicella-zoster virus glycoprotein H identifies domain-specific roles for fusion and skin tropism ⬇️

scientific article published on October 24, 2011

T-cell tropism and the role of ORF66 protein in pathogenesis of varicella-zoster virus infection

scientific article

The C-terminus of varicella-zoster virus glycoprotein M contains trafficking motifs that mediate skin virulence in the SCID-human model of VZV pathogenesis

The N-terminus of varicella-zoster virus glycoprotein B has a functional role in fusion

scientific article published on 07 January 2021

The immediate-early 63 protein of Varicella-Zoster virus: analysis of functional domains required for replication in vitro and for T-cell and skin tropism in the SCIDhu model in vivo.

scientific article published on February 2004

The latency-associated transcript locus of herpes simplex virus 1 is a virulence determinant in human skin

scientific article published on 28 December 2020

The ubiquitous cellular transcriptional factor USF targets the varicella-zoster virus open reading frame 10 promoter and determines virulence in human skin xenografts in SCIDhu mice in vivo

scientific article published on 24 January 2007

VZV: pathogenesis and the disease consequences of primary infection ⬇️

scientific article published on February 25, 2011

Varicella zoster virus ORF25 gene product: an essential hub protein linking encapsidation proteins and the nuclear egress complex

scientific article published on 26 October 2011

Varicella-zoster virus (VZV) origin of DNA replication oriS influences origin-dependent DNA replication and flanking gene transcription.

scientific article published on 17 March 2015

Varicella-zoster virus T cell tropism and the pathogenesis of skin infection

scientific article

Varicella-zoster virus immediate-early protein 62 blocks interferon regulatory factor 3 (IRF3) phosphorylation at key serine residues: a novel mechanism of IRF3 inhibition among herpesviruses

scientific article

Varicella-zoster virus infection of human neural cells in vivo.

scholarly article

Varicella-zoster virus open reading frame 10 is a virulence determinant in skin cells but not in T cells in vivo

scientific article

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