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List of works by Niels van Royen

A critical review of clinical arteriogenesis research

scientific article published on December 2009

ACRA Perfusion Study

scientific article published on 01 April 2019

Additional value of transluminal attenuation gradient in CT angiography to predict hemodynamic significance of coronary artery stenosis

scientific article

Aspirin, but not clopidogrel, reduces collateral conductance in a rabbit model of femoral artery occlusion

scientific article (publication date: 20 September 2005)

Blocking Interferon β Stimulates Vascular Smooth Muscle Cell Proliferation and Arteriogenesis

scientific article published on August 24, 2010

Body Mass Index Is Associated With Microvascular Endothelial Dysfunction in Patients With Treated Metabolic Risk Factors and Suspected Coronary Artery Disease

scientific article published on 14 September 2017

CD40 in coronary artery disease: a matter of macrophages?

scientific article

Cellular and pharmacological targets to induce coronary arteriogenesis

scientific article published on February 2014

Changes in Coronary Blood Flow After Acute Myocardial Infarction: Insights From a Patient Study and an Experimental Porcine Model

scientific article

Changes in remote myocardial tissue after acute myocardial infarction and its relation to cardiac remodeling: A CMR T1 mapping study.

scientific article published on 23 June 2017

Circulating MicroRNAs Characterizing Patients with Insufficient Coronary Collateral Artery Function

scientific article published on 2 September 2015

Combined optical coherence tomography morphologic and fractional flow reserve hemodynamic assessment of non- culprit lesions to better predict adverse event outcomes in diabetes mellitus patients: COMBINE (OCT-FFR) prospective study. Rationale and d

scientific article published on 10 October 2016

Comparison of Coronary CT Angiography, SPECT, PET, and Hybrid Imaging for Diagnosis of Ischemic Heart Disease Determined by Fractional Flow Reserve

scientific article published on 16 August 2017

Coronary pressure and flow relationships in humans: phasic analysis of normal and pathological vessels and the implications for stenosis assessment: a report from the Iberian-Dutch-English (IDEAL) collaborators

scientific article

Correction: Dissecting the Effects of Ischemia and Reperfusion on the Coronary Microcirculation in a Rat Model of Acute Myocardial Infarction

scientific article published on 15 November 2016

Design of the START-trial: STimulation of ARTeriogenesis using subcutaneous application of GM-CSF as a new treatment for peripheral vascular disease. A randomized, double-blind, placebo-controlled trial

scientific article published in January 2003

Direct evidence for tumor necrosis factor-alpha signaling in arteriogenesis

scientific article

Dissecting the Effects of Ischemia and Reperfusion on the Coronary Microcirculation in a Rat Model of Acute Myocardial Infarction.

scientific article

Doppler Versus Thermodilution-Derived Coronary Microvascular Resistance to Predict Coronary Microvascular Dysfunction in Patients With Acute Myocardial Infarction or Stable Angina Pectoris.

scientific article published on 10 October 2017

Doppler-derived intracoronary physiology indices predict the occurrence of microvascular injury and microvascular perfusion deficits after angiographically successful primary percutaneous coronary intervention.

scientific article published on March 2015

Downstream Influence of Coronary Stenoses on Microcirculatory Remodeling: A Histopathology Study

scientific article published on 31 October 2019

Early Detection and Treatment of the Vulnerable Coronary Plaque: Can We Prevent Acute Coronary Syndromes?

scientific article published on May 2017

Early Intravenous Beta-Blockers in Patients With ST-Segment Elevation Myocardial Infarction Before Primary Percutaneous Coronary Intervention

scientific article published on 29 March 2016

Early intravenous beta-blockers in patients undergoing primary percutaneous coronary intervention for ST-segment elevation myocardial infarction: A patient-pooled meta-analysis of randomized clinical trials

scientific article published on 14 February 2019

Effect of Face-to-Face vs Virtual Reality Training on Cardiopulmonary Resuscitation Quality: A Randomized Clinical Trial

scientific article published on 17 November 2019

Effect of additional treatment with EXenatide in patients with an Acute Myocardial Infarction (EXAMI): study protocol for a randomized controlled trial

scientific article published on November 8, 2011

Endothelial glycocalyx dimensions are reduced in growing collateral arteries and modulate leucocyte adhesion in arteriogenesis

scientific article published on 6 March 2009

Experimental models of arteriogenesis: differences and implications

scientific article

Expression of a retinoic acid signature in circulating CD34 cells from coronary artery disease patients.

scientific article

Galectin-2 expression is dependent on the rs7291467 polymorphism and acts as an inhibitor of arteriogenesis.

scientific article

Galectin-2 induces a proinflammatory, anti-arteriogenic phenotype in monocytes and macrophages

scientific article (publication date: 2015)

In vivo assessment of myocardial viability after acute myocardial infarction: A head-to-head comparison of the perfusable tissue index by PET and delayed contrast-enhanced CMR.

scientific article published on 2 February 2016

Inflammatory cell content of coronary thrombi is dependent on thrombus age in patients with ST-elevation myocardial infarction

scientific article published on 8 November 2016

Innate immune cells in the pathophysiology of calcific aortic valve disease: lessons to be learned from atherosclerotic cardiovascular disease?

scientific article published in 2022

Instantaneous wave-free ratio to guide coronary revascularisation: physiological framework, validation and differences from fractional flow reserve

scientific article published on 14 February 2017

Interferon-Beta, a Decisive Factor in Angiogenesis and Arteriogenesis

scientific article

Intramyocardial haemorrhage after acute myocardial infarction

scientific article

Invasive measurement of coronary microvascular resistance in patients with acute myocardial infarction treated by primary PCI.

scientific article published on 28 May 2013

Invasive minimal Microvascular Resistance Is a New Index to Assess Microcirculatory Function Independent of Obstructive Coronary Artery Disease

scientific article published on 22 December 2016

MAb therapy against the IFN-α/β receptor subunit 1 stimulates arteriogenesis in a murine hindlimb ischaemia model without enhancing atherosclerotic burden

scientific article published on May 2015

Magnetic resonance imaging-defined areas of microvascular obstruction after acute myocardial infarction represent microvascular destruction and haemorrhage

scientific article

Non-invasive assessment of the collateral circulation in the hand: validation of the Nexfin system and relation to clinical outcome after transradial catheterisation

scientific article

One year clinical outcome of early administration of intravenous beta-blockers in patients with ST-segment elevation myocardial infarction before primary percutaneous coronary reperfusion. One year results from the EARLY-BAMI trial.

scientific article published on 21 November 2017

Pre-Emptive OCT-Guided Angioplasty of Vulnerable Intermediate Coronary Lesions: Results from the Prematurely Halted PECTUS-Trial

scientific article published on 03 December 2020

Predictors of Intramyocardial Hemorrhage After Reperfused ST-Segment Elevation Myocardial Infarction.

scientific article published on 15 August 2017

Prevalence of ischaemia in patients with a chronic total occlusion and preserved left ventricular ejection fraction

scientific article published on 01 September 2017

Reducing Microvascular Dysfunction in Revascularized Patients with ST-Elevation Myocardial Infarction by Off-Target Properties of Ticagrelor versus Prasugrel. Rationale and Design of the REDUCE-MVI Study

scientific article published on 21 April 2016

START Trial: a pilot study on STimulation of ARTeriogenesis using subcutaneous application of granulocyte-macrophage colony-stimulating factor as a new treatment for peripheral vascular disease

scientific article published on 8 August 2005

Stimulation of Collateral Vessel Growth by Inhibition of Galectin 2 in Mice Using a Single-Domain Llama-Derived Antibody

scientific article published on 09 October 2019

Stimulation of collateral artery growth: a potential treatment for peripheral artery disease

scientific article published in July 2004

Suppression of inflammatory signaling in monocytes from patients with coronary artery disease

scientific article

TCT-820 First Approach to Stimulate Arteriogenesis using Monoclonal Antibodies: Blocking the Interferon-alpha/beta Receptor Subunit 1 Stimulates Restoration of Perfusion in a Murine Hindlimb-ischemia Model Without Affecting Atherosclerosis

scientific article published on 21 October 2013

TREATMENT OF REPERFUSION INJURY WITH RECOMBINANT ADAMTS13 IN A PORCINE MODEL OF ACUTE MYOCARDIAL INFARCTION

scientific article published in March 2013

Targeting angiogenesis to restore the microcirculation after reperfused MI.

scientific article published on 16 June 2009

Targeting the dominant mechanism of coronary microvascular dysfunction with intracoronary physiology tests

scientific article

The ACRA Anatomy Study (Assessment of Disability After Coronary Procedures Using Radial Access): A Comprehensive Anatomic and Functional Assessment of the Vasculature of the Hand and Relation to Outcome After Transradial Catheterization

scientific article published in November 2017

The coronary collateral circulation: Genetic and environmental determinants in experimental models and humans

scientific article published on September 19, 2011

The emerging role of galectins in cardiovascular disease

scientific article published on 2 March 2016

The influence of microvascular injury on T1- and T2*-relaxation times after acute myocardial infarction

scientific article published on 16 January 2014

The influence of microvascular injury on native T1 and T2* relaxation values after acute myocardial infarction: implications for non-contrast-enhanced infarct assessment

scientific article

The role of ADAMTS13 in acute myocardial infarction: cause or consequence?

scientific article published on 12 May 2016

Therapeutic manipulation of the collateral circulation--future directions

scientific article published in November 2004

Use of the Instantaneous Wave-free Ratio or Fractional Flow Reserve in PCI.

scientific article published on 18 March 2017