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List of works by Stephan A Grupp

31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part one

scientific article (publication date: November 2016)

A novel antibody-TCR (AbTCR) platform combines Fab-based antigen recognition with gamma/delta-TCR signaling to facilitate T-cell cytotoxicity with low cytokine release

scientific article published on 20 November 2018

A phase I/II study of the safety and efficacy of the addition of sirolimus to tacrolimus/methotrexate graft versus host disease prophylaxis after allogeneic haematopoietic cell transplantation in paediatric acute lymphoblastic leukaemia (ALL).

scientific article

A pilot study of tandem high-dose chemotherapy with stem cell rescue as consolidation for high-risk neuroblastoma: Children's Oncology Group study ANBL00P1

scientific article published on 21 January 2013

A prospective study of G-CSF primed bone marrow as a stem-cell source for allogeneic bone marrow transplantation in children: a Pediatric Blood and Marrow Transplant Consortium (PBMTC) study

scientific article published on 07 September 2007

ASTCT Consensus Grading for Cytokine Release Syndrome and Neurologic Toxicity Associated with Immune Effector Cells

scientific article published on 25 December 2018

Adoptive cellular therapy

scientific article published on 01 January 2011

Adoptive transfer of autologous T cells improves T-cell repertoire diversity and long-term B-cell function in pediatric patients with neuroblastoma.

scientific article published on 23 October 2012

Adoptive transfer of costimulated T cells induces lymphocytosis in patients with relapsed/refractory non-Hodgkin lymphoma following CD34+-selected hematopoietic cell transplantation

scientific article published on 22 May 2003

Advances in T-cell therapy for ALL.

scientific article

Advances in the management and understanding of autoimmune lymphoproliferative syndrome (ALPS)

scientific article

Aggressive surgical therapy and radiotherapy for patients with high-risk neuroblastoma treated with rapid sequence tandem transplant

scientific article published in June 2005

Allogeneic hematopoietic cell transplantation for neuroblastoma: the CIBMTR experience

scientific article published on 18 February 2013

Allogeneic marrow transplantation in children with acute leukemia: careful comparison with chemotherapy alternatives required

scientific article published on 29 April 2010

Analysis of Time to Complete Response after Defibrotide Initiation in Patients with Hepatic Veno-Occlusive Disease/Sinusoidal Obstruction Syndrome after Hematopoietic Cell Transplantation

scientific article published on 17 September 2020

Angiogenesis inhibitor TNP-470 during bone marrow transplant: safety in a preclinical model

scientific article published on 01 April 2001

Anti-GD2 antibody with GM-CSF, interleukin-2, and isotretinoin for neuroblastoma

scientific article

Antibody-modified T cells: CARs take the front seat for hematologic malignancies

scientific article published on 27 February 2014

Antigen-independent activation enhances the efficacy of 4-1BB-costimulated CD22 CAR T cells

scientific article published on 22 April 2021

Antitumor Activity Associated with Prolonged Persistence of Adoptively Transferred NY-ESO-1 c259T Cells in Synovial Sarcoma

scientific article published on 11 June 2018

Autologous and allogeneic cellular therapies for high-risk pediatric solid tumors

scientific article published on February 2010

Beginning the CAR T cell therapy revolution in the US and EU

scientific article published on 12 April 2018

CAR T Cell Therapy in Acute Lymphoblastic Leukemia and Potential for Chronic Lymphocytic Leukemia

scientific article published on June 2016

CAR T cell viability release testing and clinical outcomes: is there a lower limit?

scientific article published on 01 November 2019

CAR T-cell therapy is effective for CD19-dim B-lymphoblastic leukemia but is impacted by prior blinatumomab therapy

scientific article published on 01 November 2019

CAR-T in the clinic: drive with care

scientific article published on 01 June 2018

CD19 alterations emerging after CD19-directed immunotherapy cause retention of the misfolded protein in the endoplasmic reticulum

scientific article published on 15 October 2018

CD19-targeted chimeric antigen receptor T-cell therapy for CNS relapsed or refractory acute lymphocytic leukaemia: a post-hoc analysis of pooled data from five clinical trials

scientific article

CD19-targeted chimeric antigen receptor T-cell therapy for acute lymphoblastic leukemia

scientific article

CD19-targeting CAR T cell immunotherapy outcomes correlate with genomic modification by vector integration

scientific article published on 01 February 2020

CD3/CD19 depleted matched and mismatched unrelated donor hematopoietic stem cell transplant with targeted T cell addback is associated with excellent outcomes in pediatric patients with non-malignant hematologic disorders

scientific article published on 09 October 2018

CRISPR-Cas9 Gene Editing for Sickle Cell Disease and β-Thalassemia

scientific article published on 05 December 2020

Cellular kinetics of CTL019 in relapsed/refractory B-cell acute lymphoblastic leukemia and chronic lymphocytic leukemia

scientific article

Challenges and opportunities for international cooperative studies in pediatric hematopoeitic cell transplantation: priorities of the Westhafen Intercontinental Group

scientific article

Children's Oncology Group's 2013 blueprint for research: stem cell transplantation.

scientific article

Chimeric Antigen Receptor T Cell Therapy During the COVID-19 Pandemic

scientific article published on 14 April 2020

Chimeric Antigen Receptor- and TCR-Modified T Cells Enter Main Street and Wall Street

scientific article

Chimeric antigen receptor (CAR) T therapies for the treatment of hematologic malignancies: clinical perspective and significance

article by Michael M Boyiadzis et al published 4 December 2018 in Journal for Immunotherapy of Cancer

Chimeric antigen receptor T cells for sustained remissions in leukemia

scientific article (publication date: 16 October 2014)

Chimeric antigen receptor T cells persist and induce sustained remissions in relapsed refractory chronic lymphocytic leukemia

scientific article published on September 2015

Chimeric antigen receptor T-cell therapy for ALL.

scientific article

Chimeric antigen receptor therapy for cancer

scientific article

Chimeric antigen receptor-modified T cells for acute lymphoid leukemia

scientific article (publication date: 18 April 2013)

Chimeric receptors containing CD137 signal transduction domains mediate enhanced survival of T cells and increased antileukemic efficacy in vivo

scientific article published on 21 April 2009

Clinical Pharmacology of Tisagenlecleucel in B-cell Acute Lymphoblastic Leukemia

scientific article published on 06 September 2018

Clinical Utilization of Chimeric Antigen Receptor T Cells in B Cell Acute Lymphoblastic Leukemia: An Expert Opinion from the European Society for Blood and Marrow Transplantation and the American Society for Blood and Marrow Transplantation

scientific article published on 18 December 2018

Clinical utilization of Chimeric Antigen Receptor T-cells (CAR-T) in B-cell acute lymphoblastic leukemia (ALL)-an expert opinion from the European Society for Blood and Marrow Transplantation (EBMT) and the American Society for Blood and Marrow Tran

scientific article published on 15 May 2019

Collection, storage, and infusion of stem cells in children with high-risk neuroblastoma: saving for a rainy day.

scientific article

Convergence of Acquired Mutations and Alternative Splicing of CD19 Enables Resistance to CART-19 Immunotherapy

scientific article

Correction to: Grading of cytokine release syndrome associated with the CAR T cell therapy tisagenlecleucel.

scientific article

Corrigendum to "Advances in T-cell therapy for ALL" [Best Pract Res Clin Haematol 27 (2014) 222-228].

scientific article published in March 2016

Current concepts in the diagnosis and management of cytokine release syndrome

scientific article

Cutting edge: Lymphoproliferation caused by Fas deficiency is dependent on the transcription factor eomesodermin.

scientific article

Cytokine Release Syndrome After Chimeric Antigen Receptor T Cell Therapy for Acute Lymphoblastic Leukemia.

scientific article

Cytokine Release Syndrome after Haploidentical Stem Cell Transplantation.

scientific article published on 16 August 2016

Cytokine release syndrome after blinatumomab treatment related to abnormal macrophage activation and ameliorated with cytokine-directed therapy.

scientific article published on 15 May 2013

Cytoplasmic micro heavy chain confers sensitivity to dexamethasone-induced apoptosis in early B-lineage acute lymphoblastic leukemia

scientific article published on 01 August 2002

Defibrotide for Patients with Hepatic Veno-Occlusive Disease/Sinusoidal Obstruction Syndrome: Interim Results from a Treatment IND Study.

scientific article

Defibrotide for the treatment of hepatic veno-occlusive disease in children after hematopoietic stem cell transplantation

scientific article published on June 2012

Defibrotide for the treatment of hepatic veno-occlusive disease/sinusoidal obstruction syndrome following nontransplant-associated chemotherapy: Final results from a post hoc analysis of data from an expanded-access program

scientific article published on 06 June 2018

Defibrotide for the treatment of hepatic veno-occlusive disease/sinusoidal obstruction syndrome with multiorgan failure

article

Diagnostic biomarkers to differentiate sepsis from cytokine release syndrome in critically ill children

scientific article published on 01 October 2020

Disease burden and conditioning regimens in ASCT1221, a randomized phase II trial in children with juvenile myelomonocytic leukemia: A Children's Oncology Group study.

scientific article published on 12 March 2018

Dissecting the tumor-immune landscape in chimeric antigen receptor T-cell therapy: key challenges and opportunities for a systems immunology approach

scientific article published on 03 March 2020

Dual CD19 and CD123 targeting prevents antigen-loss relapses after CD19-directed immunotherapies

scientific article

Earlier defibrotide initiation post-diagnosis of veno-occlusive disease/sinusoidal obstruction syndrome improves Day +100 survival following haematopoietic stem cell transplantation

scientific article published on 26 April 2017

Early and late extensive chronic graft-versus-host disease in children is characterized by different Th1/Th2 cytokine profiles: findings of the Children's Oncology Group Study ASCT0031.

scientific article

Early memory phenotypes drive T cell proliferation in patients with pediatric malignancies

scientific article published in January 2016

Effect of Tandem Autologous Stem Cell Transplant vs Single Transplant on Event-Free Survival in Patients With High-Risk Neuroblastoma: A Randomized Clinical Trial

scientific article published on 01 August 2019

Efficacy and safety of tisagenlecleucel in Japanese pediatric and young adult patients with relapsed/refractory B cell acute lymphoblastic leukemia

scientific article published on 11 November 2019

Efficacy of JAK/STAT pathway inhibition in murine xenograft models of early T-cell precursor (ETP) acute lymphoblastic leukemia.

scientific article

Engineered T cells for cancer therapy.

scientific article

Eradication of B-ALL using chimeric antigen receptor-expressing T cells targeting the TSLPR oncoprotein.

scientific article published on 3 June 2015

False-positive results with select HIV-1 NAT methods following lentivirus-based tisagenlecleucel therapy.

scientific article

Feasibility of a tandem autologous peripheral blood stem cell transplant regimen for high risk neuroblastoma in a cooperative group setting: A Pediatric Oncology Group study: A Report from the Children's Oncology Group ⬇️

scientific article published on June 28, 2012

Final results from a defibrotide treatment-IND study for patients with hepatic veno-occlusive disease/sinusoidal obstruction syndrome

scientific article published on 16 May 2018

Generation of a multi-antigen-directed immune response for durable control of acute lymphoblastic leukemia

scientific article published on 19 September 2017

Generation of a multi-antigen-directed immune response for durable control of acute lymphoblastic leukemia

scientific article

Genetic alterations activating kinase and cytokine receptor signaling in high-risk acute lymphoblastic leukemia

scientific article

Genetic mechanisms of target antigen loss in CAR19 therapy of acute lymphoblastic leukemia

article

Grading of cytokine release syndrome associated with the CAR T cell therapy tisagenlecleucel

scientific article published on 2 March 2018

High-Affinity GD2-Specific CAR T Cells Induce Fatal Encephalitis in a Preclinical Neuroblastoma Model

scientific article published on 27 November 2017

High-risk neuroblastoma treated with tandem autologous peripheral-blood stem cell-supported transplantation: long-term survival update

scientific article

Higher Reported Lung Dose Received During Total Body Irradiation for Allogeneic Hematopoietic Stem Cell Transplantation in Children With Acute Lymphoblastic Leukemia Is Associated With Inferior Survival: A Report from the Children's Oncology Group

scientific article published on 23 February 2019

IFN-γ directly inhibits murine B-cell precursor leukemia-initiating cell proliferation early in life.

scientific article published on 15 March 2017

Identification of Predictive Biomarkers for Cytokine Release Syndrome after Chimeric Antigen Receptor T-cell Therapy for Acute Lymphoblastic Leukemia

scientific article

Identifying autoimmune lymphoproliferative syndrome in children with Evans syndrome: a multi-institutional study

scientific article

IgH-V(D)J NGS-MRD measurement pre- and early post-allotransplant defines very low- and very high-risk ALL patients.

scientific article published on 10 April 2015

Immunosurveillance and survivin-specific T-cell immunity in children with high-risk neuroblastoma

scientific article published on 01 December 2006

Immunotherapy for pediatric cancer

scientific article

Impaired Death Receptor Signaling in Leukemia Causes Antigen-Independent Resistance by Inducing CAR T-cell Dysfunction

scientific article published on 30 January 2020

Improved anti-leukemia activities of adoptively transferred T cells expressing bispecific T-cell engager in mice

scientific article published on 3 June 2016

In vivo control of acute lymphoblastic leukemia by immunostimulatory CpG oligonucleotides.

scientific article published on 26 October 2006

In vivo hematopoietic stem cell modification by mRNA delivery

scientific article published on 27 July 2023

Induction of resistance to chimeric antigen receptor T cell therapy by transduction of a single leukemic B cell

scientific article published on 01 October 2018

Inhibition of precursor B-cell malignancy progression by toll-like receptor ligand-induced immune responses.

scientific article

Inhibition of tumor growth in a human neuroblastoma xenograft model with TNP-470.

scientific article

Interferon-gamma-dependent infiltration of human T cells into neuroblastoma tumors in vivo.

scientific article published on 13 October 2009

Late effects in survivors of tandem peripheral blood stem cell transplant for high-risk neuroblastoma

scientific article

Lingering effects of chemotherapy on mature T cells impair proliferation

scientific article published on 01 October 2020

Long-term protection from syngeneic acute lymphoblastic leukemia by CpG ODN-mediated stimulation of innate and adaptive immune responses.

scientific article published on 27 July 2009

Mammalian target of rapamycin inhibitors and their potential role in therapy in leukaemia and other haematological malignancies

scientific article published on 16 March 2009

Managing cytokine release syndrome associated with novel T cell-engaging therapies.

scientific article

Measuring IL-6 and sIL-6R in serum from patients treated with tocilizumab and/or siltuximab following CAR T cell therapy

scientific article published on 2 April 2016

Monocyte lineage-derived IL-6 does not affect chimeric antigen receptor T-cell function.

scientific article published on 11 May 2017

More precisely defining risk peri-HCT in pediatric ALL: pre- vs post-MRD measures, serial positivity, and risk modeling

scientific article published on 01 November 2019

Multisystem inflammatory syndrome in children and COVID-19 are distinct presentations of SARS-CoV-2

scientific article published on 30 July 2020

Natural killer cell consolidation for acute myelogenous leukemia: a cell therapy ready for prime time?

scientific article published on 19 January 2010

Nature of tumor control by permanently and transiently modified GD2 chimeric antigen receptor T cells in xenograft models of neuroblastoma

scientific article published on 7 August 2014

Naïve T-cell Deficits at Diagnosis and after Chemotherapy Impair Cell Therapy Potential in Pediatric Cancers

scientific article published on 10 January 2019

Neuroblastoma: issues in transplantation

scientific article

Neurotoxicity after CTL019 in a pediatric and young adult cohort

scientific article published on 26 September 2018

Noninvasive bioluminescent imaging of primary patient acute lymphoblastic leukemia: a strategy for preclinical modeling.

scientific article

Nonviral RNA chimeric antigen receptor-modified T cells in patients with Hodgkin lymphoma

scientific article published on 20 June 2018

Novel molecular and cellular therapeutic targets in acute lymphoblastic leukemia and lymphoproliferative disease

scientific article published on January 2008

Optimized depletion of chimeric antigen receptor T cells in murine xenograft models of human acute myeloid leukemia

scientific article published on 28 February 2017

Optimizing Chimeric Antigen Receptor T-Cell Therapy for Adults With Acute Lymphoblastic Leukemia

scientific article published on 09 December 2019

Outcomes after HLA-matched sibling transplantation or chemotherapy in children with acute lymphoblastic leukemia in a second remission after an isolated central nervous system relapse: a collaborative study of the Children's Oncology Group and the C

scientific article published on 22 November 2007

Partially CD3+-Depleted Unrelated and Haploidentical Donor Peripheral Stem Cell Transplantation Has Favorable Graft-versus-Host Disease and Survival Rates in Pediatric Hematologic Malignancy

scientific article published on 22 November 2019

Patient-reported quality of life after tisagenlecleucel infusion in children and young adults with relapsed or refractory B-cell acute lymphoblastic leukaemia: a global, single-arm, phase 2 trial

scientific article published on 09 October 2019

Phase 3 trial of defibrotide for the treatment of severe veno-occlusive disease and multi-organ failure

scientific article published on 29 January 2016

Phase I study of temsirolimus in pediatric patients with recurrent/refractory solid tumors

scientific article

Phase II trial of temsirolimus in children with high-grade glioma, neuroblastoma and rhabdomyosarcoma

scientific article

Phase-1 study of siplizumab in the treatment of pediatric patients with at least grade II newly diagnosed acute graft-versus-host disease

scientific article published on 11 August 2009

Pooled analysis of Day 100 survival for defibrotide-treated patients with hepatic veno-occlusive disease/sinusoidal obstruction syndrome and ventilator or dialysis dependence following haematopoietic cell transplantation

scientific article published on 10 March 2020

Potent efficacy of combined PI3K/mTOR and JAK or ABL inhibition in murine xenograft models of Ph-like acute lymphoblastic leukemia

scientific article published on 24 October 2016

Preclinical efficacy of daratumumab in T-cell acute lymphoblastic leukemia (T-ALL).

scientific article published on 5 January 2018

Preclinical targeting of human acute myeloid leukemia and myeloablation using chimeric antigen receptor-modified T cells

scientific article published on 04 March 2014

Prospective Evaluation of Radiation Dose Escalation in Patients With High-Risk Neuroblastoma and Gross Residual Disease After Surgery: A Report From the Children's Oncology Group ANBL0532 Study

scientific article published on 12 June 2020

Purged versus non-purged peripheral blood stem-cell transplantation for high-risk neuroblastoma (COG A3973): a randomised phase 3 trial

scientific article published on 25 July 2013

Purification of mRNA Encoding Chimeric Antigen Receptor Is Critical for Generation of a Robust T-Cell Response

scientific article published on 02 October 2018

RNA-transfected CD40-activated B cells induce functional T-cell responses against viral and tumor antigen targets: implications for pediatric immunotherapy

scientific article published on 20 November 2003

Randomized trial of hydroxychloroquine for newly diagnosed chronic graft-versus-host disease in children: a Children's Oncology Group study

scientific article

Rapamycin improves lymphoproliferative disease in murine autoimmune lymphoproliferative syndrome (ALPS)

scientific article

Rapamycin is active against B-precursor leukemia in vitro and in vivo, an effect that is modulated by IL-7-mediated signaling

scientific article

Rapid-sequence tandem transplant for children with high-risk neuroblastoma

scientific article published on 01 December 2000

Real World Experience of Tisagenlecleucel Chimeric Antigen Receptor (CAR) T-Cells Targeting CD19 in Patients with Acute Lymphoblastic Leukemia (ALL) and Diffuse Large B-Cell Lymphoma (DLBCL) Using the Center for International Blood and Marrow Transpl

scientific article

Real-World Outcomes for Pediatric and Young Adult Patients with Relapsed or Refractory (R/R) B-Cell Acute Lymphoblastic Leukemia (ALL) Treated with Tisagenlecleucel: Update from the Center for International Blood and Marrow Transplant Research (CIBMT

Real-world evidence of tisagenlecleucel for pediatric acute lymphoblastic leukemia and non-Hodgkin lymphoma

scientific article published on 01 November 2020

Reduced-intensity allogeneic transplantation in pediatric patients ineligible for myeloablative therapy: results of the Pediatric Blood and Marrow Transplant Consortium Study ONC0313

scientific article published on 15 June 2009

Reducing Ex Vivo Culture Improves the Antileukemic Activity of Chimeric Antigen Receptor (CAR) T Cells

scientific article published on 20 July 2018

Refining megatherapy, improving outcome in neuroblastoma

scientific article published on 02 March 2017

Regimen-Specific Effects of RNA-Modified Chimeric Antigen Receptor T Cells in Mice with Advanced Leukemia ⬇️

scientific article published on August 1, 2013

Relation of clinical culture method to T-cell memory status and efficacy in xenograft models of adoptive immunotherapy

scientific article published on 16 January 2014

Repeated loss of target surface antigen after immunotherapy in primary mediastinal large B cell lymphoma

scientific article published on 25 October 2016

Reply

scientific article published on 23 March 2019

Retention of CD19 intron 2 contributes to CART-19 resistance in leukemias with subclonal frameshift mutations in CD19

scientific article published on 07 October 2019

Risk factors and timing of relapse after allogeneic transplantation in pediatric ALL: for whom and when should interventions be tested?

scientific article

Risk-Adapted Preemptive Tocilizumab to Prevent Severe Cytokine Release Syndrome After CTL019 for Pediatric B-Cell Acute Lymphoblastic Leukemia: A Prospective Clinical Trial

scientific article published on 08 January 2021

Roadblocks to success for RNA CARs in solid tumors

scientific article published on December 2014

Role of the BCR complex in B cell development, activation, and leukemic transformation

scientific article

Safety and efficacy of allogeneic PBSC collection in normal pediatric donors: the pediatric blood and marrow transplant consortium experience (PBMTC) 1996-2003

scientific article published on 01 February 2005

Single agent and synergistic combinatorial efficacy of first-in-class small molecule imipridone ONC201 in hematological malignancies.

scientific article published on 20 November 2017

Single-cell antigen-specific landscape of CAR T infusion product identifies determinants of CD19-positive relapse in patients with ALL

scientific article published on 08 June 2022

Sirolimus Pharmacokinetics in Early Postmyeloablative Pediatric Blood and Marrow Transplantation ⬇️

scientific article published on December 21, 2012

Sirolimus is effective in relapsed/refractory autoimmune cytopenias: results of a prospective multi-institutional trial

scientific article

Society for Immunotherapy of Cancer (SITC) clinical practice guideline on immune effector cell-related adverse events

scientific article published on 01 December 2020

Soluble interleukin-2 receptor concentration as a biochemical indicator for acute graft-versus-host disease after allogeneic bone marrow transplantation

scientific article published on 01 June 2000

Statins are active in acute lymphoblastic leukaemia (ALL): a therapy that may treat ALL and prevent avascular necrosis.

scientific article

Subcutaneous immunoglobulin replacement following CD19-specific chimeric antigen receptor T-cell therapy for B-cell acute lymphoblastic leukemia in pediatric patients

scientific article published on 02 December 2019

Systemic and local immunity following adoptive transfer of NY-ESO-1 SPEAR T cells in synovial sarcoma

scientific article published on 24 October 2019

T cells targeting NY-ESO-1 demonstrate efficacy against disseminated neuroblastoma

scientific article published on 12 August 2015

T cells with chimeric antigen receptors have potent antitumor effects and can establish memory in patients with advanced leukemia

scientific article

TNF-receptor inhibitor therapy for the treatment of children with idiopathic pneumonia syndrome. A joint Pediatric Blood and Marrow Transplant Consortium and Children's Oncology Group Study (ASCT0521).

scientific article

Tacrolimus/sirolimus vs tacrolimus/methotrexate as GVHD prophylaxis after matched, related donor allogeneic HCT.

scientific article

Tandem high-dose therapy in rapid sequence for children with high-risk neuroblastoma

scientific article published on 01 July 2000

Targeting JAK1/2 and mTOR in murine xenograft models of Ph-like acute lymphoblastic leukemia

scientific article

Targeting Notch signaling in autoimmune and lymphoproliferative disease

scientific article published on 9 October 2007

Targeting the PI3K/AKT/mTOR signaling axis in children with hematologic malignancies

scientific article

The Future Is Now: Chimeric Antigen Receptors as New Targeted Therapies for Childhood Cancer ⬇️

scientific article published on May 15, 2012

The MAGIC algorithm probability is a validated response biomarker of treatment of acute graft-versus-host disease

scientific article published on 01 December 2019

The addition of sirolimus to tacrolimus/methotrexate GVHD prophylaxis in children with ALL: a phase 3 Children's Oncology Group/Pediatric Blood and Marrow Transplant Consortium trial.

scientific article published on 04 February 2014

The angiogenesis inhibitor tnp-470 effectively inhibits human neuroblastoma xenograft growth, especially in the setting of subclinical disease

scientific article published on 01 April 2001

The mTOR inhibitor CCI-779 induces apoptosis and inhibits growth in preclinical models of primary adult human ALL

scientific article published on 29 September 2005

The role of peritoneal drainage in veno-occlusive disease in pediatric patients post hematopoietic stem cell transplant.

scientific article published on 6 February 2018

Thoracic duct lymphatic fluid harbors phenotypically naive T cells for use in adoptive T-cell therapy

scientific article published on 01 July 2020

Thymic stromal-derived lymphopoietin induces proliferation of pre-B leukemia and antagonizes mTOR inhibitors, suggesting a role for interleukin-7Ralpha signaling

scientific article published on October 2007

Tisagenlecleucel Chimeric Antigen Receptor (CAR) T-Cell Therapy for Relapsed/Refractory Children and Young Adults with Acute Lymphoblastic Leukemia (ALL): Real World Experience from the Center for International Blood and Marrow Transplant Research (C

Tisagenlecleucel Model-Based Cellular Kinetic Analysis of Chimeric Antigen Receptor-T Cells.

scientific article published on 7 March 2019

Tisagenlecleucel for the treatment of B-cell acute lymphoblastic leukemia

scientific article published on 01 October 2018

Tisagenlecleucel in Children and Young Adults with B-Cell Lymphoblastic Leukemia.

scientific article published in February 2018

Toxicities of busulfan/melphalan versus carboplatin/etoposide/melphalan for high-dose chemotherapy with stem cell rescue for high-risk neuroblastoma.

scientific article published on 9 May 2016

Toxicity management after chimeric antigen receptor T cell therapy: one size does not fit 'ALL'.

scientific article published on 13 February 2018

Toxicity management for patients receiving novel T-cell engaging therapies.

scientific article

Treatment of Advanced Leukemia in Mice with mRNA Engineered T Cells ⬇️

scientific article published on September 23, 2011

Treatment of leukemia antigen-loss relapses occurring after CD19-targeted immunotherapies by combination of anti-CD123 and anti-CD19 chimeric antigen receptor T cells.

scientific article published on 4 November 2015

Treatment with sirolimus results in complete responses in patients with autoimmune lymphoproliferative syndrome

scientific article

Unmasking Evans syndrome: T-cell phenotype and apoptotic response reveal autoimmune lymphoproliferative syndrome (ALPS)

scientific article

Use of G-CSF in matched sibling donor pediatric allogeneic transplantation: a consensus statement from the Children's Oncology Group (COG) Transplant Discipline Committee and Pediatric Blood and Marrow Transplant Consortium (PBMTC) Executive Committ

scientific article

Veno-occlusive disease after high-dose busulfan-melphalan in neuroblastoma

scientific article published on 04 September 2018

Will post-transplantation cell therapies for pediatric patients become standard of care?

scientific article

iNKT cell cytotoxic responses control T-lymphoma growth in vitro and in vivo .

scientific article published on January 2014

mTOR inhibitors are synergistic with methotrexate: an effective combination to treat acute lymphoblastic leukemia.

scientific article published on 10 June 2008

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