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List of works by Laura Santini

4CMenB vaccine induces elite cross-protective human antibodies that compete with human factor H for binding to meningococcal fHbp

scientific article published on 02 October 2020

A universal vaccine for serogroup B meningococcus

scholarly article

Adjuvanticity of the oil-in-water emulsion MF59 is independent of Nlrp3 inflammasome but requires the adaptor protein MyD88

scientific article

Bactericidal antibodies against hypervirulent <i>Neisseria meningitidis</i> C field strains following MenC-CRM or MenACWY-CRM priming and MenACWY-CRM booster in children

scientific article published on 16 December 2020

Cocrystal structure of meningococcal factor H binding protein variant 3 reveals a new crossprotective epitope recognized by human mAb 1E6

scientific article published on 05 October 2019

Defining a protective epitope on factor H binding protein, a key meningococcal virulence factor and vaccine antigen

scientific article

Epitope mapping of a bactericidal monoclonal antibody against the factor H binding protein of Neisseria meningitidis.

scientific article

Exploiting chimeric human antibodies to characterize a protective epitope of Neisseria adhesin A, one of the Bexsero vaccine components

scientific article

Exploring host-pathogen interactions through genome wide protein microarray analysis

scientific article

Four-component Meningococcal Serogroup B Vaccine Induces Antibodies With Bactericidal Activity Against Diverse Outbreak Strains in Adolescents

scientific article published on 13 October 2020

Interlaboratory standardization of the sandwich enzyme-linked immunosorbent assay designed for MATS, a rapid, reproducible method for estimating the strain coverage of investigational vaccines

scientific article

Intranasal immunization of mice with recombinant Streptococcus gordonii expressing NadA of Neisseria meningitidis induces systemic bactericidal antibodies and local IgA.

scientific article

Investigation on the effect of immune selection on resistance to bactericidal antibodies to group B meningococci in vitro

scientific article published on 26 August 2009

Molecular Engineering of Ghfp, the Gonococcal Orthologue of Neisseria meningitidis Factor H Binding Protein

scientific article published on 6 May 2015

NadA, a novel vaccine candidate of Neisseria meningitidis

scientific article

Neisseria meningitidis GNA2132, a heparin-binding protein that induces protective immunity in humans

scientific article

Neisseria meningitidis factor H-binding protein bound to monoclonal antibody JAR5: implications for antibody synergy.

scientific article

Qualitative and quantitative assessment of meningococcal antigens to evaluate the potential strain coverage of protein-based vaccines

scientific article

Recognition of Neisseria meningitidis by the long pentraxin PTX3 and its role as an endogenous adjuvant

scientific article

Reverse vaccinology

scientific article published on 01 May 2003

Structure of the meningococcal vaccine antigen NadA and epitope mapping of a bactericidal antibody

scientific article

Synergic complement-mediated bactericidal activity of monoclonal antibodies with distinct specificity

scientific article published on 17 June 2020

The region comprising amino acids 100 to 255 of Neisseria meningitidis lipoprotein GNA 1870 elicits bactericidal antibodies

scientific article published in February 2005

Two cross-reactive monoclonal antibodies recognize overlapping epitopes on Neisseria meningitidis factor H binding protein but have different functional properties

Vaccination against Neisseria meningitidis using three variants of the lipoprotein GNA1870

scientific article

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