List of works - Toshitaka Nabeshima

A novel molecule "shati" is involved in methamphetamine-induced hyperlocomotion, sensitization, and conditioned place preference.

scientific article

ARHGAP10, which encodes Rho GTPase-activating protein 10, is a novel gene for schizophrenia risk

scientific article published on 22 July 2020

Activation of post-synaptic dopamine D₁ receptors promotes the release of tissue plasminogen activator in the nucleus accumbens via PKA signaling

scientific article published on 01 December 2007

Astroglial IFITM3 mediates neuronal impairments following neonatal immune challenge in mice

scientific article

Astroglial major histocompatibility complex class I following immune activation leads to behavioral and neuropathological changes

scientific article published on 30 January 2018

Basic and translational research on proteinase-activated receptors: regulation of nicotine reward by the tissue plasminogen activator (tPA) - plasmin system via proteinase-activated receptor 1.

scientific article published on December 2008

Behavioral abnormality and pharmacologic response in social isolation-reared mice.

scientific article published on 31 March 2009

Behavioural adaptations to addictive drugs in mice lacking the NMDA receptor epsilon1 subunit

scientific journal article

Chronic restraint stress impairs neurogenesis and hippocampus-dependent fear memory in mice: possible involvement of a brain-specific transcription factor Npas4

scientific journal article

Clozapine ameliorates epigenetic and behavioral abnormalities induced by phencyclidine through activation of dopamine D1 receptor.

scientific article published on 17 December 2013

Cognition impairment in the genetic model of aging klotho gene mutant mice: a role of oxidative stress.

scientific article published on 15 November 2002

Deletion of SHATI/NAT8L increases dopamine D1 receptor on the cell surface in the nucleus accumbens, accelerating methamphetamine dependence

scientific article published on 18 November 2013

Dopamine D1 receptors regulate protein synthesis-dependent long-term recognition memory via extracellular signal-regulated kinase 1/2 in the prefrontal cortex

scientific article published on 2 March 2007

Drug dependence, synaptic plasticity, and tissue plasminogen activator.

scientific article

Effects of antipsychotics on the behavioral deficits in human dominant-negative DISC1 transgenic mice with neonatal polyI:C treatment

scientific article published on 3 August 2011

Enduring vulnerability to reinstatement of methamphetamine-seeking behavior in glial-cell-line-derived neurotrophic factor mutant mice.

scientific article published on 13 March 2007

Exposure to enriched environments during adolescence prevents abnormal behaviours associated with histone deacetylation in phencyclidine-treated mice

scientific article published on 18 November 2011

Functional analysis of deep intronic SNP rs13438494 in intron 24 of PCLO gene

scientific article

Genetic and animal model analyses reveal the pathogenic role of a novel deletion of RELN in schizophrenia

scientific article published in Scientific Reports

Identification of novel candidate genes for treatment response to risperidone and susceptibility for schizophrenia: integrated analysis among pharmacogenomics, mouse expression, and genetic case-control association approaches

scientific article published on 22 October 2009

Induction of interferon-induced transmembrane protein 3 gene expression by lipopolysaccharide in astrocytes.

scientific article published on 10 September 2014

Involvement of hippocampal extracellular signal-regulated kinase 1/2 in spatial working memory in rats

scientific article published in September 2006

Involvement of tissue plasminogen activator-plasmin system in depolarization-evoked dopamine release in the nucleus accumbens of mice

scientific article published on 14 August 2006

Neonatal polyI:C treatment in mice results in schizophrenia-like behavioral and neurochemical abnormalities in adulthood.

scientific article published on 10 April 2009

Neural circuits containing pallidotegmental GABAergic neurons are involved in the prepulse inhibition of the startle reflex in mice

scientific article published on 6 October 2006

Neuronal PAS domain protein 4 (Npas4) controls neuronal homeostasis in pentylenetetrazole-induced epilepsy through the induction of Homer1a.

scientific article published on 9 December 2017

Plasma dehydroepiandrosterone sulfate levels in patients with major depressive disorder correlate with remission during treatment with antidepressants.

scientific article published on 10 March 2014

Possible involvement of protease-activated receptor-1 in the regulation of morphine-induced dopamine release and hyperlocomotion by the tissue plasminogen activator-plasmin system

scientific article published on 5 February 2007

Prefrontal cortex, dorsomedial striatum, and dentate gyrus are necessary in the object-based attention test in mice

scientific article published on 14 December 2020

Prenatal NMDA receptor antagonism impaired proliferation of neuronal progenitor, leading to fewer glutamatergic neurons in the prefrontal cortex

scientific article

Prenatal Nicotine Exposure Impairs the Proliferation of Neuronal Progenitors, Leading to Fewer Glutamatergic Neurons in the Medial Prefrontal Cortex

scientific article

Prostaglandin E receptor EP1 controls impulsive behavior under stress.

scientific article

Reelin has a preventive effect on phencyclidine-induced cognitive and sensory-motor gating deficits

scientific article published on 6 January 2015

Repeated methamphetamine treatment impairs recognition memory through a failure of novelty-induced ERK1/2 activation in the prefrontal cortex of mice.

scientific article

Repeated methamphetamine treatment impairs spatial working memory in rats: reversal by clozapine but not haloperidol

scientific article

Role of tissue plasminogen activator in the sensitization of methamphetamine-induced dopamine release in the nucleus accumbens.

scientific article published on 25 November 2007

Role of tumor necrosis factor-alpha in methamphetamine-induced drug dependence and neurotoxicity.

scientific article published in March 2004

SHATI/NAT8L regulates neurite outgrowth via microtubule stabilization

scientific article published on 16 September 2013

Shati/Nat8l deficiency disrupts adult neurogenesis and causes attentional impairment through dopaminergic neuronal dysfunction in the dentate gyrus

scientific article published on 10 April 2020

Silibinin attenuates cognitive deficits and decreases of dopamine and serotonin induced by repeated methamphetamine treatment.

scientific article published on 24 October 2009

The extensive nitration of neurofilament light chain in the hippocampus is associated with the cognitive impairment induced by amyloid beta in mice.

scientific article published on 11 July 2008

The long-lasting effects of cross-fostering on the emotional behavior in ICR mice.

scientific article published on 6 November 2008

The rewards of nicotine: regulation by tissue plasminogen activator-plasmin system through protease activated receptor-1

scientific journal article

The role of tissue plasminogen activator in methamphetamine-related reward and sensitization.

scientific article published in February 2005

List of works by Toshitaka Nabeshima

A novel molecule "shati" is involved in methamphetamine-induced hyperlocomotion, sensitization, and conditioned place preference.

ARHGAP10, which encodes Rho GTPase-activating protein 10, is a novel gene for schizophrenia risk

Activation of post-synaptic dopamine D₁ receptors promotes the release of tissue plasminogen activator in the nucleus accumbens via PKA signaling

Astroglial IFITM3 mediates neuronal impairments following neonatal immune challenge in mice

Astroglial major histocompatibility complex class I following immune activation leads to behavioral and neuropathological changes

Basic and translational research on proteinase-activated receptors: regulation of nicotine reward by the tissue plasminogen activator (tPA) - plasmin system via proteinase-activated receptor 1.

Behavioral abnormality and pharmacologic response in social isolation-reared mice.

Behavioural adaptations to addictive drugs in mice lacking the NMDA receptor epsilon1 subunit

Chronic restraint stress impairs neurogenesis and hippocampus-dependent fear memory in mice: possible involvement of a brain-specific transcription factor Npas4

Clozapine ameliorates epigenetic and behavioral abnormalities induced by phencyclidine through activation of dopamine D1 receptor.

Cognition impairment in the genetic model of aging klotho gene mutant mice: a role of oxidative stress.

Deletion of SHATI/NAT8L increases dopamine D1 receptor on the cell surface in the nucleus accumbens, accelerating methamphetamine dependence

Dopamine D1 receptors regulate protein synthesis-dependent long-term recognition memory via extracellular signal-regulated kinase 1/2 in the prefrontal cortex

Drug dependence, synaptic plasticity, and tissue plasminogen activator.

Effects of antipsychotics on the behavioral deficits in human dominant-negative DISC1 transgenic mice with neonatal polyI:C treatment

Enduring vulnerability to reinstatement of methamphetamine-seeking behavior in glial-cell-line-derived neurotrophic factor mutant mice.

Exposure to enriched environments during adolescence prevents abnormal behaviours associated with histone deacetylation in phencyclidine-treated mice

Functional analysis of deep intronic SNP rs13438494 in intron 24 of PCLO gene

Genetic and animal model analyses reveal the pathogenic role of a novel deletion of RELN in schizophrenia

Identification of novel candidate genes for treatment response to risperidone and susceptibility for schizophrenia: integrated analysis among pharmacogenomics, mouse expression, and genetic case-control association approaches

Induction of interferon-induced transmembrane protein 3 gene expression by lipopolysaccharide in astrocytes.

Involvement of hippocampal extracellular signal-regulated kinase 1/2 in spatial working memory in rats

Involvement of tissue plasminogen activator-plasmin system in depolarization-evoked dopamine release in the nucleus accumbens of mice

Neonatal polyI:C treatment in mice results in schizophrenia-like behavioral and neurochemical abnormalities in adulthood.

Neural circuits containing pallidotegmental GABAergic neurons are involved in the prepulse inhibition of the startle reflex in mice

Neuronal PAS domain protein 4 (Npas4) controls neuronal homeostasis in pentylenetetrazole-induced epilepsy through the induction of Homer1a.

Plasma dehydroepiandrosterone sulfate levels in patients with major depressive disorder correlate with remission during treatment with antidepressants.

Possible involvement of protease-activated receptor-1 in the regulation of morphine-induced dopamine release and hyperlocomotion by the tissue plasminogen activator-plasmin system

Prefrontal cortex, dorsomedial striatum, and dentate gyrus are necessary in the object-based attention test in mice

Prenatal NMDA receptor antagonism impaired proliferation of neuronal progenitor, leading to fewer glutamatergic neurons in the prefrontal cortex

Prenatal Nicotine Exposure Impairs the Proliferation of Neuronal Progenitors, Leading to Fewer Glutamatergic Neurons in the Medial Prefrontal Cortex

Prostaglandin E receptor EP1 controls impulsive behavior under stress.

Reelin has a preventive effect on phencyclidine-induced cognitive and sensory-motor gating deficits

Repeated methamphetamine treatment impairs recognition memory through a failure of novelty-induced ERK1/2 activation in the prefrontal cortex of mice.

Repeated methamphetamine treatment impairs spatial working memory in rats: reversal by clozapine but not haloperidol

Role of tissue plasminogen activator in the sensitization of methamphetamine-induced dopamine release in the nucleus accumbens.

Role of tumor necrosis factor-alpha in methamphetamine-induced drug dependence and neurotoxicity.

SHATI/NAT8L regulates neurite outgrowth via microtubule stabilization

Shati/Nat8l deficiency disrupts adult neurogenesis and causes attentional impairment through dopaminergic neuronal dysfunction in the dentate gyrus

Silibinin attenuates cognitive deficits and decreases of dopamine and serotonin induced by repeated methamphetamine treatment.

The extensive nitration of neurofilament light chain in the hippocampus is associated with the cognitive impairment induced by amyloid beta in mice.

The long-lasting effects of cross-fostering on the emotional behavior in ICR mice.

The rewards of nicotine: regulation by tissue plasminogen activator-plasmin system through protease activated receptor-1

The role of tissue plasminogen activator in methamphetamine-related reward and sensitization.