List of works - Akihiko Nunomura

A metabolic basis for Alzheimer disease

scientific article published on October 2003

A second look into the oxidant mechanisms in Alzheimer's disease

scientific article

Accumulation of intraneuronal amyloid-β is common in normal brain

scientific article

Alzheimer Disease: Oxidative Stress and Compensatory Responses

article

Alzheimer disease and the role of free radicals in the pathogenesis of the disease

scientific article published on February 2008

Alzheimer-specific epitopes of tau represent lipid peroxidation-induced conformations

scientific article

Amyloid beta: the alternate hypothesis

scientific article

Amyloid-beta vaccination: testing the amyloid hypothesis?: heads we win, tails you lose!

scientific article published on September 2006

Amyloid-beta, BACE, and oxidative stress in Alzheimer's disease, a commentary on "The different aggregation state of beta-amyloid 1-42 mediates different effects on oxidative stress, neurodegeneration and BACE-1 expression"

scientific article published on 04 May 2006

Amyloid-beta, tau alterations and mitochondrial dysfunction in Alzheimer disease: the chickens or the eggs?

scientific article

Antioxidant approaches for the treatment of Alzheimer's disease

scientific article published on July 2010

Antioxidant therapy in Alzheimer's disease: theory and practice

scientific article

Apoptotic and Oxidative Indicators in Alzheimer's Disease

scholarly article

Autophagocytosis of mitochondria is prominent in Alzheimer disease

scientific article

Avoidance of Apoptosis in Alzheimer's Disease.

scientific article published in March 2000

Chapter 19. Targeting Oxidative Mechanisms in Alzheimer Disease

Chronological primacy of oxidative stress in Alzheimer disease

scientific article published in May 2005

Comparative biology and pathology of oxidative stress in Alzheimer and other neurodegenerative diseases: beyond damage and response

scientific article

Consequences of RNA oxidation on protein synthesis rate and fidelity: implications for the pathophysiology of neuropsychiatric disorders

scientific article

Contribution of redox-active iron and copper to oxidative damage in Alzheimer disease

scientific article published in July 2004

Detection and localization of markers of oxidative stress by in situ methods: application in the study of Alzheimer disease

scientific article published in January 2010

High molecular weight neurofilament proteins are physiological substrates of adduction by the lipid peroxidation product hydroxynonenal

scientific article published on 3 December 2001

Hydroxynonenal adducts indicate a role for lipid peroxidation in neocortical and brainstem Lewy bodies in humans

scientific article published in February 2002

In Memoriam: Mark A. Smith, PhD: Neuroscientist and Visionary

Increased autophagic degradation of mitochondria in Alzheimer disease

scientific article published on 14 August 2007

Increased iron and free radical generation in preclinical Alzheimer disease and mild cognitive impairment

scientific article

Indices of metabolic dysfunction and oxidative stress

scientific article published on 7 March 2007

Intraneuronal amyloid beta accumulation and oxidative damage to nucleic acids in Alzheimer disease

scientific article

Involvement of oxidative stress in Alzheimer disease

scientific article

Is oxidative damage the fundamental pathogenic mechanism of Alzheimer's and other neurodegenerative diseases?

scientific article

La función del estrés oxidativo en la patogénesis de la enfermedad de Alzheimer

Lipid peroxidation and 4-hydroxy-2-nonenal formation by copper ion bound to amyloid-beta peptide

scientific article published on 29 August 2007

Metal Homeostasis and Its Relation to Oxidative Stress in Alzheimer’s Disease

Microtubule Reduction in Alzheimer's Disease and Aging Is Independent of τ Filament Formation ⬇️

scientific article published on May 1, 2003

Mitochondria: a therapeutic target in neurodegeneration

scientific article published on 21 October 2009

Mitochondrial DNA oxidative damage and repair in aging and Alzheimer's disease

scientific article published on 7 December 2012

Mitochondrial abnormalities in Alzheimer disease

Modulation of Parkinson's Disease Associated Protein Rescues Alzheimer's Disease Degeneration

scientific article published on 12 October 2016

Natural Oxidant Balance in Parkinson Disease

scholarly article by George Perry et al published 1 December 2009 in Archives of Neurology

Neurofibrillary Tangle Formation as a Protective Response to Oxidative Stress in Alzheimer’s Disease

article

Neuronal RNA oxidation is a prominent feature of dementia with Lewy bodies

scientific article published in November 2002

Neuronal RNA oxidation is a prominent feature of familial Alzheimer's disease

scientific article published in October 2004

Neuronal Survival and Death in Alzheimer Disease

Neuropathology in Alzheimer's disease: awaking from a hundred-year-old dream

scientific article published on 3 May 2006

Neuropathology of Alzheimer disease: pathognomonic but not pathogenic

scientific article

Nuclear and mitochondrial DNA oxidation in Alzheimer's disease

scientific article published on 23 January 2012

Nucleic acid oxidation in Alzheimer disease

scientific article published on 18 January 2008

Oxidative Adaptation in Aging and Alzheimer’s Disease

Oxidative Damage and Antioxidant Responses in Alzheimer's Disease

article

Oxidative Stress and Balance in Neurodegenerative Diseases

Oxidative Stress and its Implications for Future Treatments and Management of Alzheimer Disease

scientific article

Oxidative Stress in Alzheimer’s Disease: A Critical Appraisal of the Causes and the Consequences

Oxidative Stress in Parkinson`s Disease

scholarly article by Avi L. Friedlich et al published 20 May 2009 in The open pathology journal

Oxidative damage to RNA in aging and neurodegenerative disorders

scientific article published on 06 June 2012

Oxidative damage to RNA in neurodegenerative diseases

scientific article published in January 2006

Oxidative stress and neurodegeneration

scientific article

Oxidative stress and neuronal adaptation in Alzheimer disease: the role of SAPK pathways

scientific article published on October 2003

Oxidative stress in Alzheimer disease: a possibility for prevention

scientific article published on 13 April 2010

Oxidative stress: the old enemy in Alzheimer's disease pathophysiology

scientific article

P4-250 Redox-active iron oxidizes ribosomal RNa in neurons vulnerable to Alzheimer's disease

scholarly article by Kazuhiro Honda et al published July 2004 in Neurobiology of Aging

Phosphorylated tau: toxic, protective, or none of the above

scientific article published on August 2008

Prevention and treatment of Alzheimer disease and aging: antioxidants

scientific article published on February 2007

Prospects for Antioxidant Therapy in Mild Cognitive Impairment and Alzheimer's Disease

scholarly article published 2007

Protein Misfolding in Alzheimer's Disease

scholarly article published 3 December 2007

RNA and Oxidative Stress in Alzheimer's Disease: Focus on microRNAs

scientific article published on 30 November 2020

RNA oxidation in Alzheimer disease and related neurodegenerative disorders

scientific article published on 07 March 2009

Redox metals and oxidative abnormalities in human prion diseases

scientific article published on 11 August 2005

Reexamining Alzheimer's disease: evidence for a protective role for amyloid-beta protein precursor and amyloid-beta

scientific article

Ribosomal RNA in Alzheimer disease is oxidized by bound redox-active iron

scientific article

Role of Oxidative Insult and Neuronal Survival in Alzheimer’s and Parkinson’s Diseases

scholarly article

Role of mitochondrial dysfunction in Alzheimer's disease

scientific article

Role of oxidative stress in the pathophysiology of neuropsychiatric disorders

scientific article published on January 2014

Signal transduction cascades associated with oxidative stress in Alzheimer's disease

scientific article published on May 2007

Specific reaction of Met 35 in amyloid beta peptide with hypochlorous acid

scientific article published in July 2010

Sublethal RNA oxidation as a mechanism for neurodegenerative disease

scientific article published on 20 May 2008

Systemic increase of oxidative nucleic acid damage in Parkinson's disease and multiple system atrophy

scientific article published in March 2002

Tau modifiers as therapeutic targets for Alzheimer's disease

scientific article

Tau phosphorylation in Alzheimer's disease: pathogen or protector?

scientific article (publication date: April 2005)

Temporal Primacy of Oxidative Stress in the Pathological Cascade of Alzheimer Disease

The Key Role of Oxidative Stress in Alzheimer's Disease

scholarly article published 2007

The Potential Application of Antioxidant Agents in Alzheimer Disease Therapeutics

The concept of redox balance in Alzheimer's disease: Mark Anthony Smith 1965–2010

scholarly article by Xiongwei Zhu et al published March 2011 in Redox Report

The earliest stage of cognitive impairment in transition from normal aging to Alzheimer disease is marked by prominent RNA oxidation in vulnerable neurons

scientific article published on March 2012

The neuronal expression of MYC causes a neurodegenerative phenotype in a novel transgenic mouse

scientific article published on 22 January 2009

The role of oxidative stress in the pathophysiology of cerebrovascular lesions in Alzheimer's disease

scientific article

The state versus amyloid-beta: the trial of the most wanted criminal in Alzheimer disease

scientific article

Therapeutic options in Alzheimer's disease

scientific article published on June 2006

Thinking Outside the Box in Alzheimer Disease Treatment

Three histidine residues of amyloid-beta peptide control the redox activity of copper and iron

scientific article published on 11 October 2007

Treatment advances in Alzheimer's disease based on the oxidative stress model

scientific article

Untangling the Vascular Web from Alzheimer Disease and Oxidative Stress ⬇️

scientific article published on January 1, 2012

Vascular oxidative stress in Alzheimer disease

scientific article

[Vascular cognitive impairment]

scientific article published on 01 December 2011

List of works by Akihiko Nunomura

A metabolic basis for Alzheimer disease

A second look into the oxidant mechanisms in Alzheimer's disease

Accumulation of intraneuronal amyloid-β is common in normal brain

Alzheimer Disease: Oxidative Stress and Compensatory Responses

Alzheimer disease and the role of free radicals in the pathogenesis of the disease

Alzheimer-specific epitopes of tau represent lipid peroxidation-induced conformations

Amyloid beta: the alternate hypothesis

Amyloid-beta vaccination: testing the amyloid hypothesis?: heads we win, tails you lose!

Amyloid-beta, BACE, and oxidative stress in Alzheimer's disease, a commentary on "The different aggregation state of beta-amyloid 1-42 mediates different effects on oxidative stress, neurodegeneration and BACE-1 expression"

Amyloid-beta, tau alterations and mitochondrial dysfunction in Alzheimer disease: the chickens or the eggs?

Antioxidant approaches for the treatment of Alzheimer's disease

Antioxidant therapy in Alzheimer's disease: theory and practice

Apoptotic and Oxidative Indicators in Alzheimer's Disease

Autophagocytosis of mitochondria is prominent in Alzheimer disease

Avoidance of Apoptosis in Alzheimer's Disease.

Chapter 19. Targeting Oxidative Mechanisms in Alzheimer Disease

Chronological primacy of oxidative stress in Alzheimer disease

Comparative biology and pathology of oxidative stress in Alzheimer and other neurodegenerative diseases: beyond damage and response

Consequences of RNA oxidation on protein synthesis rate and fidelity: implications for the pathophysiology of neuropsychiatric disorders

Contribution of redox-active iron and copper to oxidative damage in Alzheimer disease

Detection and localization of markers of oxidative stress by in situ methods: application in the study of Alzheimer disease

High molecular weight neurofilament proteins are physiological substrates of adduction by the lipid peroxidation product hydroxynonenal

Hydroxynonenal adducts indicate a role for lipid peroxidation in neocortical and brainstem Lewy bodies in humans

In Memoriam: Mark A. Smith, PhD: Neuroscientist and Visionary

Increased autophagic degradation of mitochondria in Alzheimer disease

Increased iron and free radical generation in preclinical Alzheimer disease and mild cognitive impairment

Indices of metabolic dysfunction and oxidative stress

Intraneuronal amyloid beta accumulation and oxidative damage to nucleic acids in Alzheimer disease

Involvement of oxidative stress in Alzheimer disease

Is oxidative damage the fundamental pathogenic mechanism of Alzheimer's and other neurodegenerative diseases?

La función del estrés oxidativo en la patogénesis de la enfermedad de Alzheimer

Lipid peroxidation and 4-hydroxy-2-nonenal formation by copper ion bound to amyloid-beta peptide

Metal Homeostasis and Its Relation to Oxidative Stress in Alzheimer’s Disease

Microtubule Reduction in Alzheimer's Disease and Aging Is Independent of τ Filament Formation ⬇️

Mitochondria: a therapeutic target in neurodegeneration

Mitochondrial DNA oxidative damage and repair in aging and Alzheimer's disease

Mitochondrial abnormalities in Alzheimer disease

Modulation of Parkinson's Disease Associated Protein Rescues Alzheimer's Disease Degeneration

Natural Oxidant Balance in Parkinson Disease

Neurofibrillary Tangle Formation as a Protective Response to Oxidative Stress in Alzheimer’s Disease

Neuronal RNA oxidation is a prominent feature of dementia with Lewy bodies

Neuronal RNA oxidation is a prominent feature of familial Alzheimer's disease

Neuronal Survival and Death in Alzheimer Disease

Neuropathology in Alzheimer's disease: awaking from a hundred-year-old dream

Neuropathology of Alzheimer disease: pathognomonic but not pathogenic

Nuclear and mitochondrial DNA oxidation in Alzheimer's disease

Nucleic acid oxidation in Alzheimer disease

Oxidative Adaptation in Aging and Alzheimer’s Disease

Oxidative Damage and Antioxidant Responses in Alzheimer's Disease

Oxidative Stress and Balance in Neurodegenerative Diseases

Oxidative Stress and its Implications for Future Treatments and Management of Alzheimer Disease

Oxidative Stress in Alzheimer’s Disease: A Critical Appraisal of the Causes and the Consequences

Oxidative Stress in Parkinson`s Disease

Oxidative damage to RNA in aging and neurodegenerative disorders

Oxidative damage to RNA in neurodegenerative diseases

Oxidative stress and neurodegeneration

Oxidative stress and neuronal adaptation in Alzheimer disease: the role of SAPK pathways

Oxidative stress in Alzheimer disease: a possibility for prevention

Oxidative stress: the old enemy in Alzheimer's disease pathophysiology

P4-250 Redox-active iron oxidizes ribosomal RNa in neurons vulnerable to Alzheimer's disease

Phosphorylated tau: toxic, protective, or none of the above

Prevention and treatment of Alzheimer disease and aging: antioxidants

Prospects for Antioxidant Therapy in Mild Cognitive Impairment and Alzheimer's Disease

Protein Misfolding in Alzheimer's Disease

RNA and Oxidative Stress in Alzheimer's Disease: Focus on microRNAs

RNA oxidation in Alzheimer disease and related neurodegenerative disorders

Redox metals and oxidative abnormalities in human prion diseases

Reexamining Alzheimer's disease: evidence for a protective role for amyloid-beta protein precursor and amyloid-beta

Ribosomal RNA in Alzheimer disease is oxidized by bound redox-active iron

Role of Oxidative Insult and Neuronal Survival in Alzheimer’s and Parkinson’s Diseases

Role of mitochondrial dysfunction in Alzheimer's disease

Role of oxidative stress in the pathophysiology of neuropsychiatric disorders

Signal transduction cascades associated with oxidative stress in Alzheimer's disease

Specific reaction of Met 35 in amyloid beta peptide with hypochlorous acid

Sublethal RNA oxidation as a mechanism for neurodegenerative disease

Systemic increase of oxidative nucleic acid damage in Parkinson's disease and multiple system atrophy

Tau modifiers as therapeutic targets for Alzheimer's disease

Tau phosphorylation in Alzheimer's disease: pathogen or protector?

Temporal Primacy of Oxidative Stress in the Pathological Cascade of Alzheimer Disease