Search filters

List of works by Ofelia Olivero

3'-azido-3'-deoxythymidine (AZT) transplacental perfusion kinetics and DNA incorporation in normal human placentas perfused with AZT

scientific article published on 01 July 1999

Absence of structural or functional alterations in male and female reproductive organs of F1 and F2 generations derived from female mice exposed to 3'-azido-3'-deoxythymidine during pregnancy

scientific article published in April 2000

Anaphase-telophase analysis of chromosomal damage induced by chemicals

scientific article published on 01 January 1984

Anti-centrosome antibodies in breast cancer are the expression of autoimmunity

scientific article

Antiretroviral activity of aminothiols, WR2721 and WR1065.

scientific article

Antiretroviral activity of the aminothiol WR1065 against Human Immunodeficiency virus (HIV-1) in vitro and Simian Immunodeficiency virus (SIV) ex vivo

scientific article

Asian scientists and the "glass ceiling"

scientific article

Assessment of multiple types of DNA damage in human placentas from smoking and nonsmoking women in the Czech Republic

scientific article

Association between GSTM1*0 and squamous dysplasia of the esophagus in the high risk region of Linxian, China

journal article published in 2000

Autoantibodies in breast cancer sera are not epiphenomena and may participate in carcinogenesis

scientific article published on 15 May 2015

Benzo[a]pyrene (BP) DNA adduct formation in DNA repair-deficient p53 haploinsufficient [Xpa(-/-)p53(+/-)] and wild-type mice fed BP and BP plus chlorophyllin for 28 days

scientific article

Centrosomal amplification and aneuploidy induced by the antiretroviral drug AZT in hamster and human cells

scientific article

Centrosome amplification induced by the antiretroviral nucleoside reverse transcriptase inhibitors lamivudine, stavudine, and didanosine

scientific article

Centrosome structure and function under normal and pathological conditions

scientific article published on 01 October 2009

Chromosome site-specific immunohistochemical detection of DNA adducts in N-acetoxy-2-acetylaminofluorene--exposed Chinese hamster ovary cells

scientific article

Chronic in vitro exposure to 3'-azido-2', 3'-dideoxythymidine induces senescence and apoptosis and reduces tumorigenicity of metastatic mouse mammary tumor cells

scientific article

Cisplatin-DNA damage in p21WAF1/Cip1 deficient mouse keratinocytes exposed to cisplatin

scientific article published on 8 December 2006

Continuous exposure to the carcinogenic antiretroviral drug Zidovudine (AZT) alters metabolism of human cells in vitro ⬇️

conference abstract published in 2005

Correspondence re: S. M. Melana et al., Inhibition of cell growth and telomerase activity of breast cancer cells in vitro by 3'-azido-3'-deoxythymidine. Clin. Cancer Res., 4: 693-696, 1998 ⬇️

scientific article published on 01 October 1998

Cytogenetic effect of malathion assessed by the micronucleus test

scientific article published in December 1982

Diversity Is a Strength of Cancer Research in the U.S.

scientific article published on 01 September 2020

Effect of caffeine on the frequency of chromosome aberrations induced in vivo by triethylenemelamine (TEM) and adriamycin (ADR) in mice ⬇️

scientific article published on 01 July 1981

Elevated mitochondrial cisplatin-DNA adduct levels in rat tissues after transplacental cisplatin exposure.

scientific article published in January 1997

Enhancement by caffeine of the frequency of anaphase-telophase chromatin bridges induced by triethylenemelamine (TEM)

scientific article published on 01 March 1980

Genomic instability induced by AZT in cultured normal human mammary epithelial cells (NHMECs) generates aneuploidy.

scientific article

Genotoxicity and mitochondrial damage in human lymphocytic cells chronically exposed to 3'-azido-2',3'-dideoxythymidine

scientific article published on 01 May 1997

Genotoxicity assessed by the comet and GPA assays following in vitro exposure of human lymphoblastoid cells (H9) or perinatal exposure of mother-child pairs to AZT or AZT-3TC.

scientific article published on April 2007

Genotoxicity of 3'-azido-3'-deoxythymidine in the human lymphoblastoid cell line, TK6: relationships between DNA incorporation, mutant frequency, and spectrum of deletion mutations in HPRT

scientific article

Harnessing the Power of Collaboration and Training Within Clinical Data Science to Generate Real-World Evidence in the Era of Precision Oncology

scientific article published on 05 June 2019

Human inter-individual variability in metabolic pathways and genotoxic response to zidovudine ⬇️

conference abstract published in 2006

Human inter-individual variability in metabolism and genotoxic response to zidovudine

journal article published in 2008

Impact of EMS outreach: successful developments in Latin America

scientific article

In vivo dose-response relationship in bone-marrow cells of mice treated with adriamycin

scientific article published on 01 October 1980

Incorporation of 3'-azido-3'-deoxythymidine (AZT) into fetal DNA and fetal tissue distribution of drug after infusion of pregnant late-term rhesus macaques with a human-equivalent AZT dose

scientific article published on 01 December 1999

Incorporation of zidovudine into cord blood DNA of infants and peripheral blood DNA of their HIV-1-positive mothers

scientific article published on 01 November 2000

Incorporation of zidovudine into leukocyte DNA from HIV-1-positive adults and pregnant women, and cord blood from infants exposed in utero

scientific article

Introduction: Special Issue on Transplacental/Transgenerational Mutagenesis and Carcinogenesis

scientific article published on 25 April 2019

Irreversible telomere shortening by 3'-azido-2',3'-dideoxythymidine (AZT) treatment

scientific article published on 01 May 1998

Localization of DNA adducts induced by N-acetoxy-N-2-acetylaminofluorene in chinese hamster ovary cells using electron microscopy and colloidal gold ⬇️

scientific article published on July 1, 1990

Long-term AZT exposure alters the metabolic capacity of cultured human lymphoblastoid cells

scientific article

Long-term mitochondrial toxicity in HIV-uninfected infants born to HIV-infected mothers

scientific article published on 01 June 2003

Malathion-induced chromosomal aberrations in bone-marrow cells of mice: dose-response relationships

scientific article published in November 1983

Mechanisms of genotoxicity of nucleoside reverse transcriptase inhibitors

scientific article

Mitochondrial toxicity in fetal Erythrocebus patas monkeys exposed transplacentally to zidovudine plus lamivudine

scientific article published in January 2004

Morphological and molecular course of mitochondrial pathology in cultured human cells exposed long-term to Zidovudine

scientific article published on 01 April 2007

Multiorgan transplacental and neonatal carcinogenicity of 3'-azido-3'-deoxythymidine in mice

scientific article

Mutagenicity of zidovudine, lamivudine, and abacavir following in vitro exposure of human lymphoblastoid cells or in utero exposure of CD-1 mice to single agents or drug combinations

scientific article published on April 2007

Nuclear bud formation: a novel manifestation of Zidovudine genotoxicity

scientific article

Oxidative DNA damage in fetal tissues after transplacental exposure to 3'-azido-3'-deoxythymidine (AZT)

scientific article published on 01 May 2000

Perinatal exposure of patas monkeys to antiretroviral nucleoside reverse-transcriptase inhibitors induces genotoxicity persistent for up to 3 years of age

scientific article published on 04 April 2013

Perinatal genotoxicity and carcinogenicity of anti-retroviral nucleoside analog drugs

scientific article published in September 2004

Plasma and cellular markers of 3'-azido-3'-dideoxythymidine (AZT) metabolism as indicators of DNA damage in cord blood mononuclear cells from infants receiving prepartum NRTIs

scientific article published on 01 April 2007

Plasma drug levels compared with DNA incorporation of 3'-azido-3'-deoxythymidine (AZT) in adult cynomolgus (Macaca fascicularis) monkeys.

scientific article published in May 2001

Polycyclic aromatic hydrocarbon-DNA adducts in cervix of women infected with carcinogenic human papillomavirus types: an immunohistochemistry study

scientific article

Potential toxicities of HIV therapeutics in the developing infant

scientific article published on 01 May 2000

Preferential binding of cisplatin to mitochondrial DNA of Chinese hamster ovary cells

scientific article published on 01 April 1995

Preferential formation and decreased removal of cisplatin–DNA adducts in Chinese hamster ovary cell mitochondrial DNA as compared to nuclear DNA ⬇️

scientific article published on June 13, 1997

Preferential incorporation of 3'-azido-2',3'-dideoxythymidine into telomeric DNA and Z-DNA-containing regions of Chinese hamster ovary cells

scientific article published on 01 January 1993

Relationships between DNA incorporation, mutant frequency, and loss of heterozygosity at the TK locus in human lymphoblastoid cells exposed to 3'-azido-3'-deoxythymidine

scientific article

Relevance of experimental models for investigation of genotoxicity induced by antiretroviral therapy during human pregnancy

scientific article published on 12 January 2008

Role of nucleotide excision repair and p53 in zidovudine (AZT)-induced centrosomal deregulation

scientific article

Selective protection of zidovudine-induced DNA-damage by the antioxidants WR-1065 and tempol.

scientific article published on 16 May 2014

Semiquantitation of polycyclic aromatic hydrocarbon-DNA adducts in human esophagus by immunohistochemistry and the automated cellular imaging system

scientific article

Skin tumorigenesis and Ki-ras and Ha-ras mutations in tumors from adult mice exposed in utero to 3′-azido-2′,3′-dideoxythymidine ⬇️

scientific article published on September 1, 1998

Tamoxifen induces expression of immune response-related genes in cultured normal human mammary epithelial cells

journal article published in 2009

The mutagenic effect of thiram analysed by the micronucleus test and the anaphase-telophase test

scientific article published on 01 December 1982

Transcriptional signatures of normal human mammary epithelial cells in response to benzo[a]pyrene exposure: a comparison of three microarray platforms

journal article published in 2005

Transplacental Carcinogenesis Induced by Antiretrovirals, Twelve Years Later

scientific article published on 17 April 2019

Transplacental Effects of 3'-Azido-2',3'-Dideoxythymidine (AZT): Tumorigenicity in Mice and Genotoxicity in Mice and Monkeys ⬇️

scientific article published on November 5, 1997

Transplacental cisplatin exposure induces persistent fetal mitochondrial and genomic DNA damage in patas monkeys.

scientific article published in January 1997

Transplacental genotoxicity of combined antiretroviral nucleoside analogue therapy in Erythrocebus patas monkeys

scientific article published in April 2002

Use of Ciliogenesis to Detect Aneugens: The Role of Primary Cilia

scientific article

Vaginal epithelial DNA damage and expression of preneoplastic markers in mice during chronic dosing with tumorigenic levels of 3'-azido-2',3'-dideoxythymidine

scientific article

Variability in interindividual genotoxic responses in normal human mammary epithelial (NHME) cells exposed to zidovudine

conference abstract published in 2003

WR1065 mitigates AZT-ddI-induced mutagenesis and inhibits viral replication

scientific article

Zidovudine induces S-phase arrest and cell cycle gene expression changes in human cells

scientific article published on 22 March 2005

Zidovudine-didanosine coexposure potentiates DNA incorporation of zidovudine and mutagenesis in human cells

scientific article published in November 2000

Paulina is supported by:

About Paulina

Help