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List of works by Paola A Marignani

Activation of tumor suppressor LKB1 by honokiol abrogates cancer stem-like phenotype in breast cancer via inhibition of oncogenic Stat3.

scientific article published on 5 June 2017

Acyl chain dependence of diacylglycerol activation of protein kinase C activity in vitro

scientific article published on 01 August 1996

Adenovirus-Mediated Drug-Sensitivity Gene Therapy for Hepatocellular Carcinoma

scientific article published on January 1, 2000

Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge ahead

scientific article

Association of protein kinase Cmu with type II phosphatidylinositol 4-kinase and type I phosphatidylinositol-4-phosphate 5-kinase

scientific article published on 01 September 1998

Collagen phagocytosis is regulated by the guanine nucleotide exchange factor Vav2.

scientific article

Correction: Loss of lkb1 Expression Reduces the Latency of ErbB2-Mediated Mammary Gland Tumorigenesis, Promoting Changes in Metabolic Pathways

scientific article published on 26 February 2013

Diradylglycerol formation is altered by n-3 highly unsaturated fatty acids, with differences between eicosapentaenoic (EPA) and docosahexaenoic (DHA) acids

scientific article published on January 1, 1997

Formation of second messenger diradylglycerol in murine peritoneal macrophages is altered after in vivo (n-3) polyunsaturated fatty acid supplementation

scientific article published on December 1995

Histamine receptor 2 blockade reduces breast tumor development and metastasis (TUM9P.1010)

scientific article published in May 2015

LKB1 associates with Brg1 and is necessary for Brg1-induced growth arrest

scientific article (publication date: 31 August 2001)

LKB1 catalytic activity contributes to estrogen receptor alpha signaling

scientific article published on 15 April 2009

LKB1 catalytically deficient mutants enhance cyclin D1 expression.

scientific article

LKB1, the multitasking tumour suppressor kinase

scientific article

Loss of LKB1 expression reduces the latency of ErbB2-mediated mammary gland tumorigenesis, promoting changes in metabolic pathways

scientific article

MA24.11 Loss of Tumour Suppressors is Adequate and Sufficient to Drive Lung Cancer in CRISPR/Cas9 Mice

scientific article published in October 2018

Mechanisms of environmental chemicals that enable the cancer hallmark of evasion of growth suppression.

scientific article

Molecular profiling of non-small cell lung cancer

scientific article published on 05 August 2020

Multiple phosphoinositide 3-kinase-dependent steps in activation of protein kinase B

scientific article

Novel splice isoforms of STRADalpha differentially affect LKB1 activity, complex assembly and subcellular localization.

scientific article

Omega-3 polyunsaturated fatty acid promotes the inhibition of glycolytic enzymes and mTOR signaling by regulating the tumor suppressor LKB1

scientific article published on 6 September 2013

P1‐153: Identification of Novel Biomarkers Involved in the Development of Alzheimer's Disease

scientific article published in July 2016

P3.13-31 Creating a Precision Medicine Pipeline for Lung Cancers.

scientific article published in October 2018

Pre-clinical study of drug combinations that reduce breast cancer burden due to aberrant mTOR and metabolism promoted by LKB1 loss

scientific article

Profiling non-small cell lung cancer reveals that PD-L1 is associated with wild type EGFR and vascular invasion, and immunohistochemistry quantification of PD-L1 correlates weakly with RT-qPCR

scientific article published on 06 May 2021

Prolactin-inducible EDD E3 ubiquitin ligase promotes TORC1 signalling, anti-apoptotic protein expression, and drug resistance in breast cancer cells

scientific article published on 01 July 2019

Ranitidine Inhibition of Breast Tumor Growth Is B Cell Dependent and Associated With an Enhanced Antitumor Antibody Response

scientific article published on 15 August 2018

Ranitidine modifies myeloid cell populations and inhibits breast tumor development and spread in mice.

scientific article published on 10 March 2016

Regulation of cell surface protease receptor S100A10 by retinoic acid therapy in acute promyelocytic leukemia (APL)

scholarly article by Ryan W Holloway et al published 11 September 2018 in Cell Death and Disease

S100A10 Has a Critical Regulatory Function in Mammary Tumor Growth and Metastasis: Insights Using MMTV-PyMT Oncomice and Clinical Patient Sample Analysis

scientific article published on 07 December 2020

Single-Cell RNA Sequencing Analysis Using Fluidigm C1 Platform for Characterization of Heterogeneous Transcriptomes

Single-cell RNA sequencing for the identification of early-stage lung cancer biomarkers from circulating blood

scientific article published on 15 October 2021

TAZ: a novel transcriptional co-activator regulated by interactions with 14-3-3 and PDZ domain proteins

scientific article

Target gene therapy for alpha-fetoprotein-producing hepatocellular carcinoma by E1B55k-attenuated adenovirus

scientific article

Targeting mTOR and Glycolysis in HER2-Positive Breast Cancer

scientific article published on 11 June 2021

The Tumor Suppressor Kinase LKB1: Metabolic Nexus

scientific article published on 28 April 2022

The formation of diradylglycerol molecular species in murine peritoneal macrophages varies dose-dependently with dietary purified eicosapentaenoic and docosahexaenoic ethyl esters

scientific article

Triptolide: An inhibitor of a disintegrin and metalloproteinase 10 (ADAM10) in cancer cells

scientific article published on 14 November 2009

Vav2 is required for cell spreading

scientific article

n-3 polyunsaturated fatty acid-induced changes in the molecular species composition of diradylglycerol in murine peritoneal macrophages remain stable during incubation ex vivo

scientific article published on 01 July 1996