List of works - Umar Mahmood

A container closure system that allows for greater recovery of radiolabeled peptide compared to the standard borosilicate glass system ⬇️

scientific article published on June 24, 2013

A multimodal nanoparticle for preoperative magnetic resonance imaging and intraoperative optical brain tumor delineation.

scientific article

A novel mouse model for segmental orthotopic colon cancer

scientific article published on November 2005

Arthritis critically dependent on innate immune system players

scientific article published in February 2002

Arthritis imaging using a near-infrared fluorescence folate-targeted probe

scientific article

Baseline total lesion glycolysis measured with (18)F-FDG PET/CT as a predictor of progression-free survival in diffuse large B-cell lymphoma: a pilot study ⬇️

scientific article published on April 9, 2013

Both p16(Ink4a) and the p19(Arf)-p53 pathway constrain progression of pancreatic adenocarcinoma in the mouse

scholarly article

Catheter-based in vivo imaging of enzyme activity and gene expression: feasibility study in mice

scientific article published in June 2004

Coded aperture nuclear scintigraphy: a novel small animal imaging technique

scientific article published in October 2002

Colonic adenocarcinomas: near-infrared microcatheter imaging of smart probes for early detection--study in mice

scientific article published on 16 May 2007

Denervation protects limbs from inflammatory arthritis via an impact on the microvasculature

scientific article

Design and demonstration of a small-animal up-conversion imager

scientific article published on December 2008

Detection of early antiangiogenic effects in human colon adenocarcinoma xenografts: in vivo changes of tumor blood volume in response to experimental VEGFR tyrosine kinase inhibitor

scientific article published on October 2005

Detection of invasive colon cancer using a novel, targeted, library-derived fluorescent peptide

scientific article

Development of a time domain fluorimeter for fluorescent lifetime multiplexing analysis

scientific article published on September 2008

Effective use of PI3K and MEK inhibitors to treat mutant Kras G12D and PIK3CA H1047R murine lung cancers

scientific article

Efficacy of sunitinib and radiotherapy in genetically engineered mouse model of soft-tissue sarcoma

scientific article published on July 2009

Feasibility of in vivo multichannel optical imaging of gene expression: experimental study in mice

scientific article published on 01 August 2002

Fluorescent nanoparticle uptake for brain tumor visualization

scientific article

Genotype Directed Therapy in Murine Mismatch Repair Deficient Tumors ⬇️

scientific article published on July 23, 2013

Human breast cancer tumor models: molecular imaging of drug susceptibility and dosing during HER2/neu-targeted therapy

scientific article

Identification of the target self-antigens in reperfusion injury

scientific article

Imaging inflammation of the pancreatic islets in type 1 diabetes

scholarly article

Improved detection of ovarian cancer metastases by intraoperative quantitative fluorescence protease imaging in a pre-clinical model

scientific article

Improved in vivo whole-animal detection limits of green fluorescent protein-expressing tumor lines by spectral fluorescence imaging.

scientific article published on July 2007

In Vivo Optical Molecular Imaging of Matrix Metalloproteinase Activity following Celecoxib Therapy for Colorectal Cancer ⬇️

scientific article published on September 1, 2012

In vivo imaging of protease activity in arthritis: a novel approach for monitoring treatment response

scientific article published on 01 August 2004

In vivo imaging of proteolytic activity in atherosclerosis

article

In vivo quantitative microvasculature phenotype imaging of healthy and malignant tissues using a fiber-optic confocal laser microprobe

scientific article

In vivo selection of phage for the optical imaging of PC-3 human prostate carcinoma in mice

scientific article

Inflammatory arthritis can be reined in by CpG-induced DC-NK cell cross talk.

scientific article

MIPortal: a high capacity server for molecular imaging research.

scientific article published in October 2005

Magnetic resonance imaging and characterization of spontaneous lesions in a transgenic mouse model of tuberous sclerosis as a model for endothelial cell-based transgene delivery

scientific article published on December 2005

Metformin—an Adjunct Antineoplastic Therapy—Divergently Modulates Tumor Metabolism and Proliferation, Interfering with Early Response Prediction by 18F-FDG PET Imaging ⬇️

scientific article published on February 1, 2013

Miniaturized multichannel near infrared endoscope for mouse imaging

scientific article published in October 2003

Molecular Imaging

scientific article

Multiparameter noninvasive assessment of treatment susceptibility, drug target inhibition and tumor response guides cancer treatment

scientific article published on December 2007

Multitargeted Tyrosine Kinase Inhibition Produces Discordant Changes Between99mTc-MDP Bone Scans and Other Disease Biomarkers: Analysis of a Phase II Study of Sunitinib for Metastatic Castration-Resistant Prostate Cancer ⬇️

scientific article published on September 14, 2012

N-cadherin and keratinocyte growth factor receptor mediate the functional interplay between Ki-RASG12V and p53V143A in promoting pancreatic cell migration, invasion, and tissue architecture disruption

scientific article

Near infrared thoracoscopy of tumoral protease activity for improved detection of peripheral lung cancer

scientific article published on 01 June 2006

Near-infrared fluorescent nanoparticles as combined MR/optical imaging probes

scientific article

Near-infrared optical imaging of proteases in cancer ⬇️

scientific article published on May 1, 2003

Non-invasive optical detection of cathepsin K-mediated fluorescence reveals osteoclast activity in vitro and in vivo.

scientific article published on 22 October 2008

Noninvasive imaging of pancreatic inflammation and its reversal in type 1 diabetes

scientific article

Noninvasive optical detection of bone mineral

scientific article published on August 2007

Novel multiwavelength microscopic scanner for mouse imaging

scientific article published in November 2005

Optical Imaging of Matrix Metalloproteinase–2 Activity in Tumors: Feasibility Study in a Mouse Model ⬇️

scientific article published on November 1, 2001

Pan and sentinel lymph node visualization using a near-infrared fluorescent probe

scientific article published on 01 January 2003

Particularities of the vasculature can promote the organ specificity of autoimmune attack.

scientific article published on 29 January 2006

Quantitative real-time catheter-based fluorescence molecular imaging in mice

scientific article published in November 2007

RSNA International Trends: A Global Perspective on the COVID-19 Pandemic and Radiology in Late 2020

scientific article published on 08 December 2020

Real-time multichannel imaging framework for endoscopy, catheters, and fixed geometry intraoperative systems.

scientific article published in May 2007

Regression of drug-resistant lung cancer by the combination of rosiglitazone and carboplatin.

scientific article published on October 2008

Simultaneous fluorescence imaging of protease expression and vascularity during murine colonoscopy for colonic lesion characterization

scientific article published in October 2006

Some tools for molecular imaging

scientific article published on 01 June 2002

Study of the metabolism of choline and phosphatidylcholine in tumors in vivo using phosphonium‐choline ⬇️

scientific article published on 01 November 1997

Targeted nanoparticles for imaging incipient pancreatic ductal adenocarcinoma

scientific article

The impact of human EGFR kinase domain mutations on lung tumorigenesis and in vivo sensitivity to EGFR-targeted therapies

scientific article

Therapeutic Efficacy and Fate of Bimodal Engineered Stem Cells in Malignant Brain Tumors ⬇️

scientific article published on August 1, 2013

Tomographic fluorescence imaging of tumor vascular volume in mice

scientific article published on March 2007

Treatment of Schwannomas with an Oncolytic Recombinant Herpes Simplex Virus in Murine Models of Neurofibromatosis Type 2

Treatment of schwannomas with an oncolytic recombinant herpes simplex virus in murine models of neurofibromatosis type 2.

scientific article

Upconverting luminescent nanomaterials: application to in vivo bioimaging.

scientific article published on 12 June 2009

Use of molecular imaging to quantify response to IKK-2 inhibitor treatment in murine arthritis

scientific article published on 01 January 2007

Visualizing the dynamics of EGFR activity and antiglioma therapies in vivo.

scientific article published in August 2007

List of works by Umar Mahmood

A container closure system that allows for greater recovery of radiolabeled peptide compared to the standard borosilicate glass system ⬇️

A multimodal nanoparticle for preoperative magnetic resonance imaging and intraoperative optical brain tumor delineation.

A novel mouse model for segmental orthotopic colon cancer

Arthritis critically dependent on innate immune system players

Arthritis imaging using a near-infrared fluorescence folate-targeted probe

Baseline total lesion glycolysis measured with (18)F-FDG PET/CT as a predictor of progression-free survival in diffuse large B-cell lymphoma: a pilot study ⬇️

Both p16(Ink4a) and the p19(Arf)-p53 pathway constrain progression of pancreatic adenocarcinoma in the mouse

Catheter-based in vivo imaging of enzyme activity and gene expression: feasibility study in mice

Coded aperture nuclear scintigraphy: a novel small animal imaging technique

Colonic adenocarcinomas: near-infrared microcatheter imaging of smart probes for early detection--study in mice

Denervation protects limbs from inflammatory arthritis via an impact on the microvasculature

Design and demonstration of a small-animal up-conversion imager

Detection of early antiangiogenic effects in human colon adenocarcinoma xenografts: in vivo changes of tumor blood volume in response to experimental VEGFR tyrosine kinase inhibitor

Detection of invasive colon cancer using a novel, targeted, library-derived fluorescent peptide

Development of a time domain fluorimeter for fluorescent lifetime multiplexing analysis

Effective use of PI3K and MEK inhibitors to treat mutant Kras G12D and PIK3CA H1047R murine lung cancers

Efficacy of sunitinib and radiotherapy in genetically engineered mouse model of soft-tissue sarcoma

Feasibility of in vivo multichannel optical imaging of gene expression: experimental study in mice

Fluorescent nanoparticle uptake for brain tumor visualization

Genotype Directed Therapy in Murine Mismatch Repair Deficient Tumors ⬇️

Human breast cancer tumor models: molecular imaging of drug susceptibility and dosing during HER2/neu-targeted therapy

Identification of the target self-antigens in reperfusion injury

Imaging inflammation of the pancreatic islets in type 1 diabetes

Improved detection of ovarian cancer metastases by intraoperative quantitative fluorescence protease imaging in a pre-clinical model

Improved in vivo whole-animal detection limits of green fluorescent protein-expressing tumor lines by spectral fluorescence imaging.

In Vivo Optical Molecular Imaging of Matrix Metalloproteinase Activity following Celecoxib Therapy for Colorectal Cancer ⬇️

In vivo imaging of protease activity in arthritis: a novel approach for monitoring treatment response

In vivo imaging of proteolytic activity in atherosclerosis

In vivo quantitative microvasculature phenotype imaging of healthy and malignant tissues using a fiber-optic confocal laser microprobe

In vivo selection of phage for the optical imaging of PC-3 human prostate carcinoma in mice

Inflammatory arthritis can be reined in by CpG-induced DC-NK cell cross talk.

MIPortal: a high capacity server for molecular imaging research.

Magnetic resonance imaging and characterization of spontaneous lesions in a transgenic mouse model of tuberous sclerosis as a model for endothelial cell-based transgene delivery

Metformin—an Adjunct Antineoplastic Therapy—Divergently Modulates Tumor Metabolism and Proliferation, Interfering with Early Response Prediction by 18F-FDG PET Imaging ⬇️

Miniaturized multichannel near infrared endoscope for mouse imaging

Molecular Imaging

Multiparameter noninvasive assessment of treatment susceptibility, drug target inhibition and tumor response guides cancer treatment

Multitargeted Tyrosine Kinase Inhibition Produces Discordant Changes Between99mTc-MDP Bone Scans and Other Disease Biomarkers: Analysis of a Phase II Study of Sunitinib for Metastatic Castration-Resistant Prostate Cancer ⬇️

N-cadherin and keratinocyte growth factor receptor mediate the functional interplay between Ki-RASG12V and p53V143A in promoting pancreatic cell migration, invasion, and tissue architecture disruption

Near infrared thoracoscopy of tumoral protease activity for improved detection of peripheral lung cancer

Near-infrared fluorescent nanoparticles as combined MR/optical imaging probes

Near-infrared optical imaging of proteases in cancer ⬇️

Non-invasive optical detection of cathepsin K-mediated fluorescence reveals osteoclast activity in vitro and in vivo.

Noninvasive imaging of pancreatic inflammation and its reversal in type 1 diabetes

Noninvasive optical detection of bone mineral

Novel multiwavelength microscopic scanner for mouse imaging

Optical Imaging of Matrix Metalloproteinase–2 Activity in Tumors: Feasibility Study in a Mouse Model ⬇️

Pan and sentinel lymph node visualization using a near-infrared fluorescent probe

Particularities of the vasculature can promote the organ specificity of autoimmune attack.

Quantitative real-time catheter-based fluorescence molecular imaging in mice

RSNA International Trends: A Global Perspective on the COVID-19 Pandemic and Radiology in Late 2020

Real-time multichannel imaging framework for endoscopy, catheters, and fixed geometry intraoperative systems.

Regression of drug-resistant lung cancer by the combination of rosiglitazone and carboplatin.

Simultaneous fluorescence imaging of protease expression and vascularity during murine colonoscopy for colonic lesion characterization

Some tools for molecular imaging

Study of the metabolism of choline and phosphatidylcholine in tumors in vivo using phosphonium‐choline ⬇️

Targeted nanoparticles for imaging incipient pancreatic ductal adenocarcinoma

The impact of human EGFR kinase domain mutations on lung tumorigenesis and in vivo sensitivity to EGFR-targeted therapies

Therapeutic Efficacy and Fate of Bimodal Engineered Stem Cells in Malignant Brain Tumors ⬇️

Tomographic fluorescence imaging of tumor vascular volume in mice

Treatment of Schwannomas with an Oncolytic Recombinant Herpes Simplex Virus in Murine Models of Neurofibromatosis Type 2

Treatment of schwannomas with an oncolytic recombinant herpes simplex virus in murine models of neurofibromatosis type 2.

Upconverting luminescent nanomaterials: application to in vivo bioimaging.

Use of molecular imaging to quantify response to IKK-2 inhibitor treatment in murine arthritis

Visualizing the dynamics of EGFR activity and antiglioma therapies in vivo.