Search filters

List of works by John Krystal

50 Hz hippocampal stimulation in refractory epilepsy: Higher level of basal glutamate predicts greater release of glutamate

scientific article published on 8 January 2016

67. Ketamine-induced Changes in Neural Noise and their Relationship to Psychosis-like Symptoms

87. Volume of Sub-Cortical Structures in Posttraumatic Stress Disorder from Multi-Site Investigation by ENIGMA and PGC Consortia

A New Genomewide Association Meta-Analysis of Alcohol Dependence

scientific article published on 14 July 2015

A New Journal: Addressing the Behavioral and Biological Effects of Chronic Stress

scientific article published on 01 January 2017

A New Rapid-Acting Antidepressant

scientific article published on 01 April 2020

A Novel, Functional and Replicable Risk Gene Region for Alcohol Dependence Identified by Genome-Wide Association Study ⬇️

scientific article published on November 7, 2011

A Unique Brain Connectome Fingerprint Predates and Predicts Response to Antidepressants

scientific article published on 23 December 2019

A broken filter: Prefrontal functional connectivity abnormalities in schizophrenia during working memory interference ⬇️

scientific article published on 03 August 2012

A comparison of ICD-11 and DSM criteria for posttraumatic stress disorder in two national samples of U.S. military veterans.

scientific article published on 6 July 2017

A comparison of methods to harmonize cortical thickness measurements across scanners and sites

scientific article published in 2022

A functional magnetic resonance imaging study of bipolar disorder: state- and trait-related dysfunction in ventral prefrontal cortices

scientific article published in June 2003

A functional neuropeptide Y Leu7Pro polymorphism associated with alcohol dependence in a large population sample from the United States

scientific article

A meta-analysis of D-cycloserine and the facilitation of fear extinction and exposure therapy

scientific article published on 07 March 2008

A multicenter study of ketamine effects on functional connectivity: Large scale network relationships, hubs and symptom mechanisms

A placebo-controlled, cross-over trial of lamotrigine in depersonalization disorder

scientific article published in March 2003

A prospective cohort study investigating factors associated with depression during medical internship

scientific article

A quantitative meta-analysis of neurocognitive functioning in posttraumatic stress disorder

scientific article

A robust and reproducible connectome fingerprint of ketamine is highly associated with the connectomic signature of antidepressants

scientific article published on 23 September 2020

AMPT Effects on Cue-Induced Craving for Cocaine

Absence of behavioral sensitization in healthy human subjects following repeated exposure to ketamine

scientific article

Absence of significant interactive effects of high-dose D-cycloserine and ethanol in healthy human subjects: preliminary insights into ethanol actions at the glycine B site of NMDA glutamate receptors

scientific article published on 20 November 2007

Accelerated DNA Methylation Aging in U.S. Military Veterans: Results From the National Health and Resilience in Veterans Study

scientific article published on 07 January 2019

Adjunctive risperidone treatment for antidepressant-resistant symptoms of chronic military service-related PTSD: a randomized trial

scientific article published on August 2011

Advances in the translational neuroscience of neurosteroids

scientific article published on 3 May 2006

Advancing drug discovery for schizophrenia

scientific article

Age, rapid-cycling, and pharmacotherapy effects on ventral prefrontal cortex in bipolar disorder: a cross-sectional study

scientific article published on 18 January 2006

Alcohol Expectancy and Cerebral Responses to Cue-Elicited Craving in Adult Nondependent Drinkers

scientific article published on 12 December 2018

Alcohol Triggers Reemergence of Ketamine-Like Experience in a Ketamine Ex-User

scientific article published in February 2017

Alcohol dependence is associated with blunted dopamine transmission in the ventral striatum

scientific article published on 14 July 2005

Altered Connectivity in Depression: GABA and Glutamate Neurotransmitter Deficits and Reversal by Novel Treatments

scientific article published on 01 April 2019

Altered Global Signal Topography in Schizophrenia

scientific article published on 4 October 2016

Altered NMDA glutamate receptor antagonist response in individuals with a family vulnerability to alcoholism

scientific article

Altered NMDA glutamate receptor antagonist response in recovering ethanol-dependent patients

scientific article published in November 2003

Altered White Matter Diffusivity of the Cingulum Angular Bundle in Posttraumatic Stress Disorder

article by Christopher L. Averill et al published 2018 in Molecular neuropsychiatry

Altered functional connectivity and low-frequency signal fluctuations in early psychosis and genetic high risk

scientific article published on 23 January 2019

Altered global brain signal in schizophrenia

scientific article

Altered metabotropic glutamate receptor 5 markers in PTSD: In vivo and postmortem evidence.

scientific article published on 17 July 2017

Altered white matter microstructural organization in posttraumatic stress disorder across 3047 adults: results from the PGC-ENIGMA PTSD consortium

scientific article published on 19 December 2019

Amygdala and hippocampal volumes in adolescents and adults with bipolar disorder

scientific article

Amygdala connectivity differs among chronic, early course, and individuals at risk for developing schizophrenia

scientific article

Amygdala volume is reduced in early course schizophrenia

scientific article published on 12 February 2016

Amygdala-hippocampal volume and the phenotypic heterogeneity of posttraumatic stress disorder: a cross-sectional study

scientific article published on April 2015

Antiglutamatergic strategies for ethanol detoxification: comparison with placebo and diazepam

scientific article published in April 2007

Apolipoprotein E gene polymorphism, posttraumatic stress disorder, and cognitive function in older U.S. veterans: Results from the National Health and Resilience in Veterans Study

scientific article published on 06 August 2019

Apolipoprotein E gene polymorphism, trauma burden, and posttraumatic stress symptoms in U.S. military veterans: Results from the National Health and Resilience in Veterans Study.

scientific article published on 24 November 2017

Applications of Morphometric and Diffusion Tensor Magnetic Resonance Imaging to the Study of Brain Abnormalities in the Alcoholism Spectrum

scientific article published on 01 January 2005

Association Between Functional Polymorphism in Neuropeptide Y Gene Promoter rs16147 and Resilience to Traumatic Stress in US Military Veterans

scientific article published in September 2017

Association Between Negative Age Stereotypes and Accelerated Cellular Aging: Evidence from Two Cohorts of Older Adults

scientific article published on 19 September 2016

Association between alcoholism and gamma-amino butyric acid alpha2 receptor subtype in a Russian population

scientific article published in April 2005

Association between common alcohol dehydrogenase gene (ADH) variants and schizophrenia and autism

scientific article published on 07 March 2013

Association between physical exercise and mental health in 1·2 million individuals in the USA between 2011 and 2015: a cross-sectional study

article

Association of Combined Naltrexone and Ketamine With Depressive Symptoms in a Case series of Patients With Depression and Alcohol Use Disorder

scientific article published on 01 March 2019

Association of Drinking Problems and Duration of Alcohol Use to Inhibitory Control in Nondependent Young Adult Social Drinkers

scientific article published on 2 February 2016

Association of posttraumatic stress disorder with reduced in vivo norepinephrine transporter availability in the locus coeruleus

scientific article

Association study of DTNBP1 with schizophrenia in a US sample

scientific article

Attachment Style Moderates Polygenic Risk for Posttraumatic Stress in United States Military Veterans: Results From the National Health and Resilience in Veterans Study

scientific article published on 30 September 2020

Attachment style moderates effects of FKBP5 polymorphisms and childhood abuse on post-traumatic stress symptoms: Results from the National Health and Resilience in Veterans Study

scientific article published on 11 September 2017

Author Correction: Neural computations of threat in the aftermath of combat trauma

scientific article published on 01 May 2019

BDNF Val66Met polymorphism and posttraumatic stress symptoms in U.S. military veterans: Protective effect of physical exercise

scientific article published on 17 October 2018

Baseline trajectories of drinking moderate acamprosate and naltrexone effects in the COMBINE study.

scientific article

Beneficial Effects of the Glutamate-modulating Agent Riluzole on Disordered Eating and Pathological Skin-picking Behaviors

scientific article published on 01 December 2006

Beneficial effects of the antiglutamatergic agent riluzole in a patient diagnosed with obsessive-compulsive disorder and major depressive disorder

scientific article published on 26 March 2003

Biological Psychiatry and Biological Psychiatry: Cognitive Neuroscience and Neuroimaging Adopt Neuroscience-Based Nomenclature

scientific article published in July 2016

Biological Psychiatry and Biological Psychiatry: Cognitive Neuroscience and Neuroimaging Adopt Neuroscience-Based Nomenclature

scientific article published on 22 June 2016

Blunted psychotomimetic and amnestic effects of delta-9-tetrahydrocannabinol in frequent users of cannabis

scientific article published on 09 January 2008

Brain-derived neurotrophic factor-5-HTTLPR gene interactions and environmental modifiers of depression in children

scientific article published on 3 February 2006

Capgras syndrome induced by ketamine in a healthy subject

scientific article

Capturing the Angel in "Angel Dust": Twenty Years of Translational Neuroscience Studies of NMDA Receptor Antagonists in Animals and Humans ⬇️

scientific article published on August 16, 2012

Cerebellar and prefrontal cortical alterations in PTSD: structural and functional evidence

scientific article published on 01 January 2018

Cerebral metabolic effects of intravenous glycine in healthy human subjects

scientific article published in December 2006

Challenges in the design and conduct of controlled clinical effectiveness trials in schizophrenia ⬇️

scientific article published on January 26, 2011

Changes in global and thalamic brain connectivity in LSD-induced altered states of consciousness are attributable to the 5-HT2A receptor

scientific article published on 25 October 2018

Characteristics of Ongoing Clinical Trials for Alcohol Use Disorder Registered on ClinicalTrials.gov

scientific article published on 27 May 2020

Characterization of the Interactive Effects of Glycine and -Cycloserine in Men: Further Evidence for Enhanced NMDA Receptor Function Associated with Human Alcohol Dependence

scientific article published on 10 February 2011

Characterization of the Interactive Effects of Glycine and D-Cycloserine in Men: Further Evidence for Enhanced NMDA Receptor Function Associated with Human Alcohol Dependence ⬇️

scientific article published on December 1, 2010

Characterizing thalamo-cortical disturbances in schizophrenia and bipolar illness

scientific article

Clinical significance of neurological soft signs in schizophrenia: factor analysis of the Neurological Evaluation Scale

scientific article published on 19 September 2010

Clinical studies implementing glutamate neurotransmission in mood disorders

scientific article

Clinical treatment of obsessive compulsive disorder ⬇️

scientific article published on November 1, 2005

Cognition in schizophrenia: from basic science to clinical treatment

scientific article published on 30 August 2003

Cognitive Neuroscience Treatment Research to Improve Cognition in Schizophrenia II: developing imaging biomarkers to enhance treatment development for schizophrenia and related disorders

scientific article

Combat Exposure Severity is Associated with Reduced Cortical Thickness in Combat Veterans: A Preliminary Report

article

Comorbidity of Alcoholism and Psychiatric Disorders: An Overview

scholarly article by Ismene L. Petrakis et al published 1 January 2002 in Alcohol Research and Health

Comparative and interactive human psychopharmacologic effects of ketamine and amphetamine: implications for glutamatergic and dopaminergic model psychoses and cognitive function

scientific article

Computational Psychiatry and the Challenge of Schizophrenia.

scientific article published on 8 March 2017

Computational psychiatry.

scientific article

Connectivity, pharmacology, and computation: toward a mechanistic understanding of neural system dysfunction in schizophrenia

scientific article published on 24 December 2013

Constance E. Lieber, Theodore R. Stanley, and the Enduring Impact of Philanthropy on Psychiatry Research

scientific article published on July 2016

Continuous Ketamine Infusion for Pain as an Opportunity for Psychotherapy for PTSD: A Case Series of Ketamine-Enhanced Psychotherapy for PTSD and Pain (KEP-P2)

scientific article published on 03 April 2020

Corpus callosum in maltreated children with posttraumatic stress disorder: a diffusion tensor imaging study

scientific article published on 04 March 2008

Correction: Dose-Related Effects of Adjunctive Ketamine in Taiwanese Patients with Treatment-Resistant Depression

Correlates of Nonimprovement to Pharmacotherapy for Chronic, Antidepressant-Resistant, Military Service-Related Posttraumatic Stress Disorder: Insights From the Veterans Affairs Cooperative Study No. 504.

scientific article published on 22 September 2017

Cortical Transcriptomic Alterations in Association with Appetitive Neuropeptides and Body Mass Index in Posttraumatic Stress Disorder

scientific article published on 19 September 2020

Cortical gamma-aminobutyric acid concentrations in depressed patients receiving cognitive behavioral therapy

scientific article

Cortical gamma-aminobutyric acid levels across the menstrual cycle in healthy women and those with premenstrual dysphoric disorder: a proton magnetic resonance spectroscopy study

scientific article

Cortical gamma-aminobutyric acid levels and the recovery from ethanol dependence: preliminary evidence of modification by cigarette smoking

scientific article

Cortical gamma-aminobutyric acid type A-benzodiazepine receptors in recovery from alcohol dependence: relationship to features of alcohol dependence and cigarette smoking

scientific article

Cortical thickness reduction in combat exposed U.S. veterans with and without PTSD.

scientific article published on 6 March 2017

Cortical volume abnormalities in posttraumatic stress disorder: an ENIGMA-psychiatric genomics consortium PTSD workgroup mega-analysis

scientific article published on 07 December 2020

Cost and Cost-Effectiveness in a Randomized Trial of Long-Acting Risperidone for Schizophrenia

scientific article published on May 1, 2012

Cue-elicited craving, thalamic activity, and physiological arousal in adult non-dependent drinkers

scientific article published on 08 June 2019

Decreased Beta(2)*-nicotinic acetylcholine receptor availability after chronic ethanol exposure in nonhuman primates

scientific article

Decreased SGK1 Expression and Function Contributes to Behavioral Deficits Induced by Traumatic Stress

scientific article

Decreased cerebrospinal fluid allopregnanolone levels in women with posttraumatic stress disorder

scientific article published on 24 August 2006

Decreased hippocampal volume on MRI is associated with increased extracellular glutamate in epilepsy patients

scientific article

Deep resequencing of 17 glutamate system genes identifies rare variants in DISC1 and GRIN2B affecting risk of opioid dependence

scientific article

Default mode network abnormalities in posttraumatic stress disorder: A novel network-restricted topology approach

Differences in treatment effect among clinical subgroups in a randomized clinical trial of long-acting injectable risperidone and oral antipsychotics in unstable chronic schizophrenia

scientific article

Differential brain response to alcohol cue distractors across stages of alcohol dependence.

scientific article

Dimensional predictors of response to SRI pharmacotherapy in obsessive-compulsive disorder

scientific article published on 03 July 2009

Dimensional structure of DSM-5 posttraumatic stress disorder symptoms: results from the National Health and Resilience in Veterans Study

scientific article

Dopamine and serotonin transporter availability during acute alcohol withdrawal: effects of comorbid tobacco smoking

scientific article published on 13 May 2009

Dose-Related Target Occupancy and Effects on Circuitry, Behavior, and Neuroplasticity of the Glycine Transporter-1 Inhibitor PF-03463275 in Healthy and Schizophrenia Subjects

scientific article published on 31 January 2018

Drinking and responses to antidrinking messages among young adults: An fMRI study

scientific article published on 18 February 2020

Early-course unmedicated schizophrenia patients exhibit elevated prefrontal connectivity associated with longitudinal change

scientific article

Effect of memantine on cue-induced alcohol craving in recovering alcohol-dependent patients

scientific article published in March 2007

Effects of Memantine on Event-Related Potential, Oscillations, and Complexity in Individuals With and Without Family Histories of Alcoholism ⬇️

scientific article published on March 1, 2013

Effects of NMDA receptor antagonists: implications for the pathophysiology of schizophrenia

scientific article published in July 2002

Effects of ketamine in treatment-refractory obsessive-compulsive disorder

scientific article published on 10 July 2012

Efficacy of d-cycloserine for enhancing response to cognitive-behavior therapy for panic disorder

scientific article published on 6 October 2009

Elucidating the transdiagnostic dimensional structure of trauma-related psychopathology: Findings from VA cooperative study 504 - risperidone treatment for military service related chronic post traumatic stress disorder

scientific article published on 22 October 2014

Enhanced Striatal Dopamine Release to Expectation of Alcohol: A Potential Risk Factor for Alcohol Use Disorder

scientific article published on 21 April 2018

Enhanced sensitivity to the euphoric effects of alcohol in schizophrenia

scientific article published on 20 September 2006

Epigenome-Wide DNA Methylation Association Analysis Identified Novel Loci in Peripheral Cells for Alcohol Consumption Among European American Male Veterans

scientific article published on 30 August 2019

Epigenome-wide association study of posttraumatic stress disorder identifies novel loci in U.S. military veterans

scientific article published on 17 February 2022

Evaluation of the sensitivity of the novel α4β2* nicotinic acetylcholine receptor PET radioligand 18F-(-)-NCFHEB to increases in synaptic acetylcholine levels in rhesus monkeys

scientific article

Exome-Wide Association Study of Replicable Nonsynonymous Variants Conferring Risk for Alcohol Dependence ⬇️

scientific article published on July 1, 2013

Extracellular metabolites in the cortex and hippocampus of epileptic patients

scientific article published on February 2005

FKBP5 polymorphisms, childhood abuse, and PTSD symptoms: Results from the National Health and Resilience in Veterans Study.

scientific article published on 5 April 2016

Familial Alcoholism Risk and the Ratio of Stimulant to Sedative Effects of Ketamine

scientific article published on 25 September 2015

Family history of alcoholism influences naltrexone-induced reduction in alcohol drinking.

scientific article published on 6 March 2007

Family psychopathology and magnitude of reductions in occipital cortex GABA levels in panic disorder

scientific article published in March 2004

Fore-period effect and stop-signal reaction time

scientific article

From translational neuroscience to personalized medicine

scientific article published on 06 February 2015

Frontostriatal abnormalities in adolescents with bipolar disorder: preliminary observations from functional MRI.

scientific article published in July 2003

Frontotemporal neural systems in bipolar disorder

scientific article

Functional hierarchy underlies preferential connectivity disturbances in schizophrenia

scientific article

Functional neuroimaging and electrophysiology biomarkers for clinical trials for cognition in schizophrenia

scientific article

GRIK1 and GABRA2 Variants Have Distinct Effects on the Dose-Related Subjective Response to Intravenous Alcohol in Healthy Social Drinkers

scientific article

Gamma-aminobutyric acid type A receptors and alcoholism: intoxication, dependence, vulnerability, and treatment

scientific article published on September 2006

Gene-based and pathway-based genome-wide association study of alcohol dependence

scientific article published on April 2015

Genetic and environmental predictors of early alcohol use.

scientific article published on 21 November 2006

Genetically regulated multi-omics study for symptom clusters of posttraumatic stress disorder highlights pleiotropy with hematologic and cardio-metabolic traits

scientific article published in 2022

Genome-Wide Association Study of Alcohol Dependence Implicates KIAA0040 on Chromosome 1q.

scientific article published on 13 December 2011

Genome-wide association study identifies glutamate ionotropic receptor GRIA4 as a risk gene for comorbid nicotine dependence and major depression

article

Genome-wide association study of alcohol dependence implicates KIAA0040 on chromosome 1q

scientific journal article

Genome-wide search for replicable risk gene regions in alcohol and nicotine co-dependence

scientific journal article

Genome-wide significant association signals in IPO11-HTR1A region specific for alcohol and nicotine codependence

scientific article published on 6 December 2012

Global prefrontal and fronto-amygdala dysconnectivity in bipolar I disorder with psychosis history

scientific article published on 11 September 2012

Global resting-state functional magnetic resonance imaging analysis identifies frontal cortex, striatal, and cerebellar dysconnectivity in obsessive-compulsive disorder.

scientific article

Glutamate and norepinephrine interaction: Relevance to higher cognitive operations and psychopathology

scientific article

Glutamate dysregulation and glutamatergic therapeutics for PTSD: Evidence from human studies

scientific article published on December 2016

Glutamate metabolism in major depressive disorder

scientific article published on 31 October 2014

Glutamate-modulating drugs as novel pharmacotherapeutic agents in the treatment of obsessive-compulsive disorder

scientific article

Glutamatergic model psychoses: prediction error, learning, and inference

scientific article

Glutamatergic modulation of auditory information processing in the human brain

scientific article

Glycine treatment of the risk syndrome for psychosis: report of two pilot studies

scientific article

Going up in smoke? A review of nAChRs-based treatment strategies for improving cognition in schizophrenia

scientific article published on January 2014

High burden of subthreshold DSM-5 post-traumatic stress disorder in U.S. military veterans

scientific article published on June 2016

Histidine decarboxylase deficiency causes tourette syndrome: parallel findings in humans and mice

scientific article

Hostility and telomere shortening among U.S. military veterans: Results from the National Health and Resilience in Veterans Study

scientific article published on 15 September 2016

How mental health care should change as a consequence of the COVID-19 pandemic

scientific article published on 16 July 2020

Identifying cognitive mechanisms targeted for treatment development in schizophrenia: an overview of the first meeting of the Cognitive Neuroscience Treatment Research to Improve Cognition in Schizophrenia Initiative

scientific article published on 07 May 2008

Illusions and delusions: relating experimentally-induced false memories to anomalous experiences and ideas

scientific article

Illusory generalizability of clinical prediction models

scientific article published on 11 January 2024

Imaging human reward processing with positron emission tomography and functional magnetic resonance imaging ⬇️

scientific article published on November 4, 2011

Imaging the neurochemistry of alcohol and substance abuse

scientific article published on November 2007

Impact of intravenous nicotine on BOLD signal response to photic stimulation

scientific article published in February 2002

Impaired GABA neuronal response to acute benzodiazepine administration in panic disorder

scientific article published on December 2004

Impaired Potentiation of Theta Oscillations During a Visual Cortical Plasticity Paradigm in Individuals With Schizophrenia

scientific article published on 16 December 2020

Impaired Tuning of Neural Ensembles and the Pathophysiology of Schizophrenia: A Translational and Computational Neuroscience Perspective

scientific article

Impaired visual cortical plasticity in schizophrenia

scientific article published on March 2012

Impairment of working memory maintenance and response in schizophrenia: functional magnetic resonance imaging evidence

scientific article published on 27 September 2008

In Reply

In vivo evidence for dysregulation of mGluR5 as a biomarker of suicidal ideation

scientific article published on 13 May 2019

In vivo ketamine-induced changes in [¹¹C]ABP688 binding to metabotropic glutamate receptor subtype 5.

scientific article

Increased brain uptake and oxidation of acetate in heavy drinkers ⬇️

scientific article published on March 8, 2013

Increased cortical GABA concentrations in depressed patients receiving ECT.

scientific article

Increased occipital cortex GABA concentrations in depressed patients after therapy with selective serotonin reuptake inhibitors

scientific article

Individuals family history positive for alcoholism show functional magnetic resonance imaging differences in reward sensitivity that are related to impulsivity factors

scientific article

Influence of combined treatment with naltrexone and memantine on alcohol drinking behaviors: a phase II randomized crossover trial

scientific article published on 07 October 2019

Initial evidence of the beneficial effects of glutamate-modulating agents in the treatment of self-injurious behavior associated with borderline personality disorder.

scientific article published in November 2005

Integrating acquired preparedness and dual process models of risk for heavy drinking and related problems

scientific article

Intravenous ethanol infusion decreases human cortical γ-aminobutyric acid and N-acetylaspartate as measured with proton magnetic resonance spectroscopy at 4 tesla.

scientific article published on 19 August 2011

Introducing a New Journal, Biological Psychiatry: Global Open Science

scientific article published on 13 October 2020

Introducing a new journal: Biological Psychiatry: Cognitive Neuroscience and Neuroimaging

scientific article published on 20 April 2015

It Is Time to Address the Crisis in the Pharmacotherapy of Posttraumatic Stress Disorder: A Consensus Statement of the PTSD Psychopharmacology Working Group

scientific article

It is time to take a stand for medical research and against terrorism targeting medical scientists

scientific article

KETAMINE'S MECHANISM OF ACTION: A PATH TO RAPID-ACTING ANTIDEPRESSANTS.

scientific article published on 6 April 2016

Ketamine

Ketamine

Ketamine and rapid-acting antidepressants: a window into a new neurobiology for mood disorder therapeutics

scientific article

Ketamine as a promising prototype for a new generation of rapid-acting antidepressants

scientific article published on 27 February 2015

Ketamine effects on memory reconsolidation favor a learning model of delusions

scientific article published on 12 June 2013

Ketamine: A Paradigm Shift for Depression Research and Treatment

scientific article published on 01 March 2019

Late-life exacerbation of PTSD symptoms in US veterans: results from the National Health and Resilience in Veterans Study

scientific article published on March 2016

Linking Microcircuit Dysfunction to Cognitive Impairment: Effects of Disinhibition Associated with Schizophrenia in a Cortical Working Memory Model ⬇️

scientific article published on November 29, 2012

Locus Coeruleus Hyperactivity in Posttraumatic Stress Disorder: Answers and Questions

scientific article

Long-Acting Risperidone and Oral Antipsychotics in Unstable Schizophrenia ⬇️

scientific article published on March 3, 2011

Longitudinal imaging of metabotropic glutamate 5 receptors during early and extended alcohol abstinence

scientific article published on 12 September 2020

Lower synaptic density is associated with depression severity and network alterations

scientific article published on 04 April 2019

MAOA genotype, maltreatment, and aggressive behavior: the changing impact of genotype at varying levels of trauma

scientific article

Machine learning selected smoking-associated DNA methylation signatures that predict HIV prognosis and mortality

article

Magnetic resonance spectroscopic studies of alcoholism: from heavy drinking to alcohol dependence and back again

scientific article published in January 2005

Mapping Lithium in the Brain: New 3-Dimensional Methodology Reveals Regional Distribution in Euthymic Patients With Bipolar Disorder

scientific article published on 01 September 2020

Mazindol Augmentation of Antipsychotic Treatment for Schizophrenic Patients with Comorbid Cocaine Abuse or Dependence

Measuring the effects of ketamine on mGluR5 using [18F]FPEB and PET

scientific article published on 19 November 2019

Mecamylamine treatment for alcohol dependence: a randomized controlled trial.

scientific article

Medication compliance feedback and monitoring in a clinical trial: predictors and outcomes

scientific article published on September 2003

Mental illness and mental health

scientific article

Metabotropic Glutamatergic Receptor 5 and Stress Disorders: Knowledge Gained From Receptor Imaging Studies.

scientific article published on 19 September 2017

Mild worry symptoms predict decline in learning and memory in healthy older adults: a 2-year prospective cohort study

scientific article published on March 2012

Minimal Clinically Important Differences (MCID) in Assessing Outcomes of Post-Traumatic Stress Disorder

scientific article published on 21 June 2017

Mobilizing an institutional supportive response for healthcare workers and other staff in the context of COVID-19: The Yale experience

scientific article published on 21 November 2020

Modulation of the antidepressant effects of ketamine by the mTORC1 inhibitor rapamycin

scientific article published on 24 February 2020

Modulation of the cortical processing of novel and target stimuli by drugs affecting glutamate and GABA neurotransmission

scientific article

Moral injury in U.S. combat veterans: Results from the national health and resilience in veterans study

scientific article published on 29 March 2017

Move over ANOVA: progress in analyzing repeated-measures data and its reflection in papers published in the Archives of General Psychiatry

scientific article

Multidimensionality of the Alcohol Withdrawal Symptom Checklist: a factor analysis of the Alcohol Withdrawal Symptom Checklist and CIWA-Ar

scientific article published in April 2007

Multimodal Investigation of Network Level Effects Using Intrinsic Functional Connectivity, Anatomical Covariance, and Structure-to-Function Correlations in Unmedicated Major Depressive Disorder

scientific article

Mutation screen of the glutamate decarboxylase-67 gene and haplotype association to unipolar depression

scientific article published in January 2004

Mutation screen of theGAD2 gene and association study of alcoholism in three populations

article

N-acetylcysteine augmentation in serotonin reuptake inhibitor refractory obsessive-compulsive disorder

scientific article published on 22 December 2005

N-methyl-D-aspartate glutamate receptors and alcoholism: reward, dependence, treatment, and vulnerability

scientific article

N-methyl-D-aspartate receptor antagonism has differential effects on alcohol craving and drinking in heavy drinkers

scientific article

N-methyl-D-aspartate receptor antagonist effects on prefrontal cortical connectivity better model early than chronic schizophrenia

scientific article

NKAIN1–SERINC2 is a functional, replicable and genome-wide significant risk gene region specific for alcohol dependence in subjects of European descent ⬇️

scientific article published on February 28, 2013

NMDA glutamate receptor antagonism and the heritable risk for alcoholism: new insights from a study of nitrous oxide

scientific article

NMDA receptor antagonism and the ethanol intoxication signal: from alcoholism risk to pharmacotherapy

scientific article published on November 2003

NMDA receptor antagonist effects, cortical glutamatergic function, and schizophrenia: toward a paradigm shift in medication development

scientific article (publication date: September 2003)

NMDA receptor function in large-scale anticorrelated neural systems with implications for cognition and schizophrenia

scientific article

Naltrexone and combined behavioral intervention effects on trajectories of drinking in the COMBINE study.

scientific article

Naltrexone augmentation of neuroleptic treatment in alcohol abusing patients with schizophrenia

scientific article published on 21 November 2003

Naltrexone is associated with reduced drinking by alcohol dependent patients receiving antidepressants for mood and anxiety symptoms: results from VA Cooperative Study No. 425, "Naltrexone in the treatment of alcoholism".

scientific article published on 7 December 2007

Neural Correlates of Impulsivity in Healthy Males and Females with Family Histories of Alcoholism ⬇️

scientific article published on April 12, 2013

Neural computations of threat in the aftermath of combat trauma

scientific article published on 21 January 2019

Neural synchrony in schizophrenia: from networks to new treatments

scientific article

Neurobiology of posttraumatic stress disorder (PTSD): A path from novel pathophysiology to innovative therapeutics

scientific article published in May 2017

Neuroimaging insights into the role of cortical GABA systems and the influence of nicotine on the recovery from alcohol dependence

scientific article

Neuroimaging-based classification of PTSD using data-driven computational approaches: A multisite big data study from the ENIGMA-PGC PTSD consortium

scientific article published on 18 October 2023

Neuroplasticity as a target for the pharmacotherapy of anxiety disorders, mood disorders, and schizophrenia

scientific article

Neuropsychological Functioning in Veterans with Posttraumatic Stress Disorder: Associations with Performance Validity, Comorbidities, and Functional Outcomes.

scientific article

Neurotoxicity, neuroplasticity, and magnetic resonance imaging morphometry

scientific article published in August 2003

New insights into the efficacy of naltrexone based on trajectory-based reanalyses of two negative clinical trials

scientific article

Noradrenergic and serotonergic mechanisms in the neurobiology of posttraumatic stress disorder and resilience

scientific article

Noradrenergic vs serotonergic antidepressant with or without naltrexone for veterans with PTSD and comorbid alcohol dependence

scientific article published on 16 November 2011

Opioid receptor gene (OPRM1, OPRK1, and OPRD1) variants and response to naltrexone treatment for alcohol dependence: results from the VA Cooperative Study

scientific article

Oxytocin receptor gene polymorphisms, attachment, and PTSD: Results from the National Health and Resilience in Veterans Study

scientific article published on 08 July 2017

PTSD and the War of Words

scientific article published on 01 January 2018

PTSD is associated with neuroimmune suppression: evidence from PET imaging and postmortem transcriptomic studies

scientific article published on 12 May 2020

PTSD: from neurobiology to pharmacological treatments

scientific article

Pediatric psychopharmacology: mood, anxiety and disruptive behavior/pervasive developmental disorders

scientific article published in March 2007

Personalised pharmacotherapy: an interim solution for antidepressant treatment?

scientific article published on 14 May 2015

Physical activity and mental health – Author's reply

article

Planning the New National Institute on Substance Use and Addiction Disorders ⬇️

scientific article published on June 8, 2012

Plasma proteomic alterations in non-human primates and humans after chronic alcohol self-administration.

scientific article

Polygenic Scores for Major Depressive Disorder and Risk of Alcohol Dependence

scientific article

Population admixture modulates risk for alcohol dependence

scientific article published on 22 March 2009

Positron emission tomography imaging of the serotonin transporter and 5-HT(1A) receptor in alcohol dependence

scientific article published on 29 October 2008

Posttraumatic Stress Disorder and Depression Symptom Severities Are Differentially Associated With Hippocampal Subfield Volume Loss in Combat Veterans

article by Christopher L Averill et al published 13 December 2017 in Chronic Stress

Posttraumatic Stress Disorder: An Integrated Overview of the Neurobiological Rationale for Pharmacology

scientific article published on 18 July 2017

Posttraumatic stress symptom courses in U.S. military veterans: A seven-year, nationally representative, prospective cohort study

scientific article published on 12 September 2019

Potential psychiatric applications of metabotropic glutamate receptor agonists and antagonists

scientific article published on August 2010

Potentiation of low dose ketamine effects by naltrexone: potential implications for the pharmacotherapy of alcoholism

scientific article published on 4 January 2006

Practitioner review: adolescent alcohol use disorders: assessment and treatment issues

scientific article

Predicting Barriers to Treatment for Depression in a U.S. National Sample: A Cross-Sectional, Proof-of-Concept Study

Prefrontal Connectivity and Glutamate Transmission: Relevance to Depression Pathophysiology and Ketamine Treatment

article

Preliminary analysis of positive and negative syndrome scale in ketamine-associated psychosis in comparison with schizophrenia

scientific article published on 24 December 2014

Preliminary evidence for medication effects on functional abnormalities in the amygdala and anterior cingulate in bipolar disorder

scientific article published on 26 October 2005

Preliminary evidence for persistent abnormalities in amygdala volumes in adolescents and young adults with bipolar disorder

scientific article published on December 2005

Preliminary evidence of attenuation of the disruptive effects of the NMDA glutamate receptor antagonist, ketamine, on working memory by pretreatment with the group II metabotropic glutamate receptor agonist, LY354740, in healthy human subjects

scientific article

Preliminary evidence of reduced occipital GABA concentrations in puerperal women: a 1H-MRS study

scientific article published on 3 May 2006

Preliminary evidence of riluzole efficacy in antidepressant-treated patients with residual depressive symptoms

scientific article published on 04 December 2006

Probable Posttraumatic Stress Disorder in the US Veteran Population According to DSM-5: Results From the National Health and Resilience in Veterans Study.

scientific article published on 13 September 2016

Probing the pathophysiology of auditory/verbal hallucinations by combining functional magnetic resonance imaging and transcranial magnetic stimulation

scientific article

Problem Drinking, Alcohol Expectancy, and Thalamic Resting-State Functional Connectivity in Nondependent Adult Drinkers

scientific article published on 01 October 2018

Proof of mechanism and target engagement of glutamatergic drugs for the treatment of schizophrenia: RCTs of pomaglumetad and TS-134 on ketamine-induced psychotic symptoms and pharmacoBOLD in healthy volunteers

scientific article published on 13 May 2020

Prospective Memory in Posttraumatic Stress Disorder

scientific article published on 29 June 2016

Psilocybin Induces Time-Dependent Changes in Global Functional Connectivity

scientific article published on 13 January 2020

Psychological resilience in U.S. military veterans: A 2-year, nationally representative prospective cohort study.

scientific article

Psychometrically improved, abbreviated versions of three classic measures of impulsivity and self-control

scientific article

RANDOMIZED TRIAL OF D-CYCLOSERINE ENHANCEMENT OF COGNITIVE-BEHAVIORAL THERAPY FOR PANIC DISORDER.

scientific article published on 17 June 2016

Rapid-acting glutamatergic antidepressants: the path to ketamine and beyond

scientific article published on June 2013

Rare ADH variant constellations are specific for alcohol dependence

scientific article

Rare SERINC2 variants are specific for alcohol dependence in individuals of European descent ⬇️

scientific article published on August 1, 2013

Rare nonsynonymous variants in alpha-4 nicotinic acetylcholine receptor gene protect against nicotine dependence

scientific article

Real-Time fMRI Neurofeedback with War Veterans with Chronic PTSD: A Feasibility Study

scientific article (publication date: 2016)

Reduced Amygdala Serotonin Transporter Binding in Posttraumatic Stress Disorder ⬇️

scientific article published on December 1, 2011

Reduced Salience and Enhanced Central Executive Connectivity Following PTSD Treatment

Reduced Salience and Enhanced Central Executive Connectivity Following PTSD Treatment

scientific article published on 01 January 2019

Reduced global functional connectivity of the medial prefrontal cortex in major depressive disorder

scientific article published on 4 May 2016

Reevaluating the Efficacy and Predictability of Antidepressant Treatments: A Symptom Clustering Approach

scientific article

Regulation of Craving and Negative Emotion in Alcohol Use Disorder

scientific article published on 28 December 2019

Repeated ketamine infusions for antidepressant-resistant PTSD: Methods of a multicenter, randomized, placebo-controlled clinical trial

scientific article published on 15 April 2019

Reply

Reply to: It Is Time to Look for New Treatments for Posttraumatic Stress Disorder: Can Sympathetic System Modulation Be an Answer?

scientific article published on 12 October 2017

Resilience: The role of accurate appraisal, thresholds, and socioenvironmental factors

scientific article published on January 2015

Restricting Benzodiazepines to Short-Term Prescription

scientific article published on 01 July 2015

Reward-Related Dorsal Striatal Activity Differences between Former and Current Cocaine Dependent Individuals during an Interactive Competitive Game ⬇️

scientific article (publication date: 2012)

Rigorous Trial Design Is Essential to Understand the Role of Opioid Receptors in Ketamine's Antidepressant Effect-Reply

scientific article published on 01 June 2019

Riluzole augmentation for treatment-resistant depression

scientific article published in November 2004

Riluzole augmentation in treatment-resistant obsessive-compulsive disorder: an open-label trial

scientific article

Riluzole in the treatment of mood and anxiety disorders

scientific article published on January 2008

Ritanserin antagonism of m-chlorophenylpiperazine effects in neuroleptic-free schizophrenics patients: support for serotonin-2 receptor modulation of schizophrenia symptoms

scientific article published on 5 April 2002

Role of GABA Deficit in Sensitivity to the Psychotomimetic Effects of Amphetamine

scientific article published on 8 May 2015

Role of N-Methyl-D-Aspartate Receptors in Action-Based Predictive Coding Deficits in Schizophrenia

scientific article

Ronald S. Duman, Ph.D. (1954-2020)

scientific article published on 19 February 2020

SPECT imaging of nicotinic acetylcholine receptors in nonsmoking heavy alcohol drinking individuals

scientific article

Salience Network Disruption in U.S. Army Soldiers With Posttraumatic Stress Disorder.

scientific article published in January 2019

Schizophrenia Exhibits Bi-Directional Brain-Wide Alterations in Cortico-Striato-Cerebellar Circuits

scholarly article published 24 July 2017

Schizophrenia Exhibits Bi-directional Brain-Wide Alterations in Cortico-Striato-Cerebellar Circuits

scientific article published on 01 December 2019

Schizophrenia is associated with a pattern of spatial working memory deficits consistent with cortical disinhibition

scientific article published on 10 October 2016

Searching for Cross-Diagnostic Convergence: Neural Mechanisms Governing Excitation and Inhibition Balance in Schizophrenia and Autism Spectrum Disorders.

scientific article

Selecting paradigms from cognitive neuroscience for translation into use in clinical trials: proceedings of the third CNTRICS meeting

scientific article

Sensory gating and psychosis vulnerability in cocaine-dependent individuals: preliminary data

scientific article

Serotonin 1B receptor imaging in alcohol dependence

scientific article

Sex Differences in Striatal Dopamine Release in Young Adults After Oral Alcohol Challenge: A Positron Emission Tomography Imaging Study With [11C]Raclopride ⬇️

scientific article published on August 3, 2010

Sex chromosome-wide association analysis suggested male-specific risk genes for alcohol dependence.

scientific article published on December 2013

Sex differences in the interacting roles of impulsivity and positive alcohol expectancy in problem drinking: A structural brain imaging study

scientific article published on 31 March 2017

Sex, GABA, and nicotine: the impact of smoking on cortical GABA levels across the menstrual cycle as measured with proton magnetic resonance spectroscopy

scientific article

Sex-related differences in amygdala activity influences immediate memory

scientific article published in March 2010

Significance of adolescent neurodevelopment for the neural circuitry of bipolar disorder

scientific article

Significant association between rare IPO11-HTR1A variants and attention deficit hyperactivity disorder in Caucasians

scientific article published on 16 June 2015

Similar psychotic and cognitive profile between ketamine dependence with persistent psychosis and schizophrenia.

scientific article published on 3 March 2018

Sleep disturbance in chronic military-related PTSD: clinical impact and response to adjunctive risperidone in the Veterans Affairs cooperative study #504.

scientific article published on 02 February 2016

Smaller Hippocampal Volume in Posttraumatic Stress Disorder: A Multisite ENIGMA-PGC Study: Subcortical Volumetry Results From Posttraumatic Stress Disorder Consortia.

scientific article published on 20 September 2017

Social supports and serotonin transporter gene moderate depression in maltreated children

scholarly article

Speaker 3: John Krystal, USA.

scientific article published on 27 May 2016

Speaker 4: John Krystal, USA.

scientific article published on 27 May 2016

Striking differences in glucose and lactate levels between brain extracellular fluid and plasma in conscious human subjects: effects of hyperglycemia and hypoglycemia.

scientific article

Subtype-specific alterations of gamma-aminobutyric acid and glutamate in patients with major depression

scientific article published in July 2004

Symptom structure and severity: a comparison of responses to the positive and negative syndrome scale (PANSS) between patients with PTSD or schizophrenia

scientific article

Synaptic Loss and the Pathophysiology of PTSD: Implications for Ketamine as a Prototype Novel Therapeutic.

scientific article published on 26 August 2017

Synaptic plasticity and depression: new insights from stress and rapid-acting antidepressants

scientific article

Systematic review and meta-analysis of the moderating effect of rs1799971 in OPRM1, the mu-opioid receptor gene, on response to naltrexone treatment of alcohol use disorder

scientific article published on 21 January 2020

Targeted neural network interventions for auditory hallucinations: Can TMS inform DBS?

scientific article

Targeting the glutamatergic system to develop novel, improved therapeutics for mood disorders

scientific article published on May 2008

Temporal patterns of adherence to medications and behavioral treatment and their relationship to patient characteristics and treatment response

scientific article published on 4 February 2013

Temporoparietal transcranial magnetic stimulation for auditory hallucinations: safety, efficacy and moderators in a fifty patient sample

scientific article

Test-retest reliability of the novel 5-HT1B receptor PET radioligand [11C]P943.

scientific article published on 27 November 2014

Thalamic Cortical Error-Related Responses in Adult Social Drinkers: Sex Differences and Problem Alcohol Use

scientific article published on 03 May 2018

The Association of PTSD Symptom Severity with Localized Hippocampus and Amygdala Abnormalities

The Connecticut Mental Health Center: Celebrating 50 Years of a Successful Partnership Between the State and Yale University

scientific article

The NMDA receptor as a therapeutic target in major depressive disorder

scientific article published on April 2007

The National Health and Resilience in Veterans Study: A Narrative Review and Future Directions

scientific article published on 09 December 2020

The Neurobiology and Pharmacotherapy of Posttraumatic Stress Disorder

scientific article published on 14 September 2018

The Self-Report Habit Index: Assessing habitual marijuana, alcohol, e-cigarette, and cigarette use.

scientific article published on 13 March 2018

The World Federation of Societies of Biological Psychiatry (WFSBP) guidelines for the biological treatment of substance use and related disorders. Part 2: Opioid dependence

scientific article

The antidepressant effect of ketamine is not associated with changes in occipital amino acid neurotransmitter content as measured by [1H]-MRS ⬇️

scientific article published on January 12, 2011

The burden of alcohol use disorders in US military veterans: results from the National Health and Resilience in Veterans Study

scientific article published on 9 April 2016

The burden of hostility in U.S. Veterans: Results from the National Health and Resilience in Veterans Study

scientific article published on 25 June 2016

The effect of early trauma exposure on serotonin type 1B receptor expression revealed by reduced selective radioligand binding

scientific article published on September 2011

The effect of tryptophan depletion on alcohol self-administration in non-treatment-seeking alcoholic individuals

scientific article published in July 2002

The effects of cannabinoids on serum cortisol and prolactin in humans

scientific article

The effects of ketamine on prefrontal glutamate neurotransmission in healthy and depressed subjects

scholarly article by Chadi Abdallah et al published September 2018 in Neuropsychopharmacology

The efficacies of clozapine and haloperidol in refractory schizophrenia are related to DTNBP1 variation

scientific article

The impact of NMDA receptor blockade on human working memory-related prefrontal function and connectivity

scientific article published on 16 July 2013

The interaction of neuroactive steroids and GABA in the development of neuropsychiatric disorders in women

scientific article published on 24 July 2006

The neurobiology of depression, ketamine and rapid-acting antidepressants: Is it glutamate inhibition or activation?

scientific article published on 25 May 2018

The resistance to depressive relapse in menopausal women undergoing tryptophan depletion: preliminary findings

scientific article published on 4 August 2006

The role of default network deactivation in cognition and disease

scientific article

The role of psychedelics in palliative care reconsidered: A case for psilocybin

scientific article published in December 2016

The vulnerability to alcohol and substance abuse in individuals diagnosed with schizophrenia

scientific article published on December 2006

Tobacco smoking interferes with GABAA receptor neuroadaptations during prolonged alcohol withdrawal

scientific article

Topology of brain functional connectivity networks in posttraumatic stress disorder

scientific article published on 06 September 2018

Torgny Svensson, M.D., Ph.D. (1945-2020)

scientific article published on 22 July 2020

Toward early pharmacological posttraumatic stress intervention ⬇️

scientific article published on May 1, 2003

Toward illness phase-specific pharmacotherapy for schizophrenia

scientific article published in December 2015

Trajectories of alcohol consumption in U.S. military veterans: Results from the National Health and Resilience in Veterans Study.

scientific article published on 18 April 2018

Trajectories of depression severity in clinical trials of duloxetine: insights into antidepressant and placebo responses

scientific article

Trajectories of relapse in randomised, placebo-controlled trials of treatment discontinuation in major depressive disorder: an individual patient-level data meta-analysis

scientific article

Transcranial magnetic stimulation of left temporoparietal cortex and medication-resistant auditory hallucinations.

scientific article published on January 2003

Transcriptomic organization of the human brain in post-traumatic stress disorder

scientific article published on 21 December 2020

Transdiagnostic, Connectome-Based Prediction of Memory Constructs Across Psychiatric Disorders

scientific article published on 21 December 2020

Treatment implications: using neuroscience to guide the development of new pharmacotherapies for alcoholism ⬇️

scientific article published on January 1, 2008

Treatment models and designs for intervention research during the psychotic prodrome

scientific article published on January 2003

Untangling depression and anxiety: clinical challenges

scientific article

Utility of Imaging-Based Biomarkers for Glutamate-Targeted Drug Development in Psychotic Disorders: A Randomized Clinical Trial

scientific article

Ventral anterior cingulate connectivity distinguished nonpsychotic bipolar illness from psychotic bipolar disorder and schizophrenia

scientific article

Visual Hallucinations from the Addition of Riluzole to Memantine and Bupropion

article

Web-Based Cognitive Behavioral Therapy Intervention for the Prevention of Suicidal Ideation in Medical Interns: A Randomized Clinical Trial

scientific article published on 4 November 2015

Web-Based Cognitive Behavioral Therapy Intervention for the Prevention of Suicidal Ideation in Medical Interns: A Randomized Clinical Trial.

scientific article published in January 2016

What I have changed my mind about and why.

scientific article

Why are some individuals more resilient than others: the role of social support

scientific article published on February 2016

Why do delusions persist?

scientific article published on 10 July 2009

Working memory overload: fronto-limbic interactions and effects on subsequent working memory function.

scientific article

Yohimbine-induced withdrawal and anxiety symptoms in opioid-dependent patients

scientific article published in April 2002

beta2 Nicotinic acetylcholine receptor availability in post-traumatic stress disorder

scientific article

gamma-Aminobutyric acid-serotonin interactions in healthy men: implications for network models of psychosis and dissociation

scientific article

Paulina is supported by:

About Paulina

Help