List of works - Naoyuki Takashima

A genome-wide association study in Japanese identified one variant associated with a preference for a Japanese dietary pattern

scientific article published on 06 December 2020

A genome-wide association study in the Japanese population identifies the 12q24 locus for habitual coffee consumption: The J-MICC Study

scientific article

A genome-wide association study on fish consumption in a Japanese population-the Japan Multi-Institutional Collaborative Cohort study

scientific article published on 07 September 2020

Association Between Glycemic Traits and Primary Open-Angle Glaucoma: A Mendelian Randomization Study in the Japanese Population

scientific article published in 2023

Association between J-point elevation and death from coronary artery disease--15-year follow up of the NIPPON DATA90.

scientific article published on 26 January 2013

Association between alcohol intake pattern and metabolic syndrome components and simulated change by alcohol intake reduction: A cross-sectional study from the Japan Multi-Institutional Collaborative Cohort Study

scientific article published on 26 September 2020

Association between brain-muscle-ARNT-like protein-2 (BMAL2) gene polymorphism and type 2 diabetes mellitus in obese Japanese individuals: A cross-sectional analysis of the Japan Multi-institutional Collaborative Cohort Study

scientific article published on 14 October 2015

Association between plasma levels of homocysteine, folate, and vitamin B12, and dietary folate intake and hypertension in a cross-sectional study

scientific article published on 28 October 2020

Association of genetic risk score and chronic kidney disease in a Japanese population

scientific article published on 29 April 2019

Associations between Dietary Patterns, ADRβ2 Gln27Glu and ADRβ3 Trp64Arg with Regard to Serum Triglyceride Levels: J-MICC Study.

scientific article published on 06 September 2016

Associations between polymorphisms of interleukin-6 and related cytokine genes and serum liver damage markers: a cross-sectional study in the Japan Multi-Institutional Collaborative Cohort (J-MICC) Study

scientific article published on 15 December 2014

Associations of apolipoprotein A5 (APOA5), glucokinase (GCK) and glucokinase regulatory protein (GCKR) polymorphisms and lifestyle factors with the risk of dyslipidemia and dysglycemia in Japanese - a cross-sectional data from the J-MICC Study

scientific article

Bundle branch block and other cardiovascular disease risk factors: US–Japan comparison

scientific article published in September 2010

Cardiovascular disease and risk factors in Asia: a selected review

scientific article

Cigarette smoking in middle age and a long-term risk of impaired activities of daily living: NIPPON DATA80.

scientific article

Coffee and metabolic phenotypes: A cross-sectional analysis of the Japan multi-institutional collaborative cohort (J-MICC) study

scientific article published in 2023

Combined effect of weight gain within normal weight range and parental hypertension on the prevalence of hypertension; from the J-MICC Study

scientific article published on 03 September 2019

Detailed Analysis of Japanese Population Substructure with a Focus on the Southwest Islands of Japan ⬇️

scientific article published on April 3, 2012

Dietary sodium-to-potassium ratio as a risk factor for stroke, cardiovascular disease and all-cause mortality in Japan: the NIPPON DATA80 cohort study.

scientific article published on 13 July 2016

Dietary tofu intake and long-term risk of death from stroke in a general population

scientific article published on 3 December 2016

Differential effect of polymorphisms on body mass index across the life course of Japanese: the Japan Multi-Institutional Collaborative Cohort Study

scientific article published on 07 March 2020

Does the flushing response modify the relationship between alcohol intake and hypertension in the Japanese population? NIPPON DATA2010.

scientific article

Effect of the PPARG2 Pro12Ala polymorphism and clinical risk factors for diabetes mellitus on HbA1c in the Japanese general population

scientific article published on 22 September 2012

Effects of self-reported calorie restriction on correlations between SIRT1 polymorphisms and body mass index and long-term weight change.

scientific article published on 31 August 2016

GCK, GCKR polymorphisms and risk of chronic kidney disease in Japanese individuals: data from the J-MICC Study.

scientific article

Gene variants in PPARD and PPARGC1A are associated with timing of natural menopause in the general Japanese population

scientific article published on 10 February 2012

Genetic Predisposition to Ischemic Stroke: A Polygenic Risk Score

scientific article published on 29 December 2016

Genetic Variants of RAMP2 and CLR are Associated with Stroke.

scientific article published on 14 September 2017

Genetic variants of SLC17A1 are associated with cholesterol homeostasis and hyperhomocysteinaemia in Japanese men.

scientific article

Genome-Wide Association Study of Renal Function Traits: Results from the Japan Multi-Institutional Collaborative Cohort Study

scientific article published on 18 May 2018

Genome-wide Association Study of Leisure-Time Exercise Behavior in Japanese Adults

scientific article

Genome-wide association meta-analysis and Mendelian randomization analysis confirm ALDH2 influencing on sleep duration in the Japanese population

scientific article published on 01 June 2019

Genome-wide association study of genetic factors related to confectionery intake: Potential roles of theADIPOQgene

scientific article published on 29 May 2013

Genome-wide meta-analysis identifies multiple novel loci associated with serum uric acid levels in Japanese individuals

scientific article published on 08 April 2019

Impact of PSCA polymorphisms on the risk of duodenal ulcer

scientific article published on 14 December 2019

Increased Aortic Calcification Is Associated With Arterial Stiffness Progression in Multiethnic Middle-Aged Men.

scientific article

Independent relationships of daily life activity and leisure-time exercise with metabolic syndrome and its traits in the general Japanese population

scientific article published on 22 April 2019

Interaction between dietary marine-derived n-3 fatty acids intake and J-point elevation on the risk of cardiac death: a 24-year follow-up of Japanese men.

scientific article

Lipoprotein particle profiles compared with standard lipids in association with coronary artery calcification in the general Japanese population.

scientific article published on 25 July 2014

Lipoprotein-associated phospholipase A2 is related to risk of subclinical atherosclerosis but is not supported by Mendelian randomization analysis in a general Japanese population.

scientific article published on 23 December 2015

Long-chain n-3 polyunsaturated fatty acids intake and cardiovascular disease mortality risk in Japanese: a 24-year follow-up of NIPPON DATA80.

scientific article published on 17 December 2013

Long-term risk of BP values above normal for cardiovascular mortality

scientific article published on 01 December 2012

Low-carbohydrate diets and cardiovascular and total mortality in Japanese: a 29-year follow-up of NIPPON DATA80.

scientific article published in September 2014

Macronutrient intakes and serum oestrogen, and interaction with polymorphisms in CYP19A1 and HSD17B1 genes: a cross-sectional study in postmenopausal Japanese women

scientific article published in September 2017

Matrix metalloproteinase 9 gene polymorphisms are associated with a multiple family history of gastric cancer

scientific article published on 6 April 2016

Overweight or underweight and the risk of decline in activities of daily living in a 22-year cohort study of a Japanese sample.

scientific article

Polymorphisms in CYP19A1, HSD17B1 and HSD17B2 genes and serum sex hormone level among postmenopausal Japanese women

scientific article published on 13 August 2015

Population attributable fraction of smoking and metabolic syndrome on cardiovascular disease mortality in Japan: a 15-year follow up of NIPPON DATA90.

scientific article

Population-specific and trans-ancestry genome-wide analyses identify distinct and shared genetic risk loci for coronary artery disease

scientific article published on 05 October 2020

Pro-/anti-inflammatory cytokine gene polymorphisms and chronic kidney disease: a cross-sectional study

scientific article

Profile of participants and genotype distributions of 108 polymorphisms in a cross-sectional study of associations of genotypes with lifestyle and clinical factors: a project in the Japan Multi-Institutional Collaborative Cohort (J-MICC) Study.

scientific article published on 30 March 2011

Relationship between non-high-density lipoprotein cholesterol and the long-term mortality of cardiovascular diseases: NIPPON DATA 90.

scientific article

Secular trends of the impact of overweight and obesity on hypertension in Japan, 1980-2010.

scientific article published on 16 July 2015

Serum level of LOX-1 ligand containing ApoB is associated with increased carotid intima-media thickness in Japanese community-dwelling men, especially those with hypercholesterolemiaLOX-1 ligand and IMT in Japanese

scientific article published in 2016

Socioeconomic Status Associated With Urinary Sodium and Potassium Excretion in Japan: NIPPON DATA2010.

scientific article published in January 2018

Subtype-specific gout susceptibility loci and enrichment of selection pressure on ABCG2 and ALDH2 identified by subtype genome-wide meta-analyses of clinically defined gout patients

scientific article published on 1 April 2020

The interaction between ABCA1 polymorphism and physical activity on the HDL-cholesterol levels in a Japanese population

scientific article published on 06 November 2019

The role of initial and longitudinal change in blood pressure on progression of arterial stiffness among multiethnic middle-aged men.

scientific article published on 20 October 2016

Transethnic Meta-analysis of Genome-wide Association Studies Identifies Three New Loci and Characterizes Population-specific Differences for Coronary Artery Disease

scientific article published on 29 May 2020

Variant of the clock circadian regulator (CLOCK) gene and related haplotypes are associated with the prevalence of type 2 diabetes in the Japanese population.

scientific article published on 16 September 2015

List of works by Naoyuki Takashima

A genome-wide association study in Japanese identified one variant associated with a preference for a Japanese dietary pattern

A genome-wide association study in the Japanese population identifies the 12q24 locus for habitual coffee consumption: The J-MICC Study

A genome-wide association study on fish consumption in a Japanese population-the Japan Multi-Institutional Collaborative Cohort study

Association Between Glycemic Traits and Primary Open-Angle Glaucoma: A Mendelian Randomization Study in the Japanese Population

Association between J-point elevation and death from coronary artery disease--15-year follow up of the NIPPON DATA90.

Association between alcohol intake pattern and metabolic syndrome components and simulated change by alcohol intake reduction: A cross-sectional study from the Japan Multi-Institutional Collaborative Cohort Study

Association between brain-muscle-ARNT-like protein-2 (BMAL2) gene polymorphism and type 2 diabetes mellitus in obese Japanese individuals: A cross-sectional analysis of the Japan Multi-institutional Collaborative Cohort Study

Association between plasma levels of homocysteine, folate, and vitamin B12, and dietary folate intake and hypertension in a cross-sectional study

Association of genetic risk score and chronic kidney disease in a Japanese population

Associations between Dietary Patterns, ADRβ2 Gln27Glu and ADRβ3 Trp64Arg with Regard to Serum Triglyceride Levels: J-MICC Study.

Associations between polymorphisms of interleukin-6 and related cytokine genes and serum liver damage markers: a cross-sectional study in the Japan Multi-Institutional Collaborative Cohort (J-MICC) Study

Associations of apolipoprotein A5 (APOA5), glucokinase (GCK) and glucokinase regulatory protein (GCKR) polymorphisms and lifestyle factors with the risk of dyslipidemia and dysglycemia in Japanese - a cross-sectional data from the J-MICC Study

Bundle branch block and other cardiovascular disease risk factors: US–Japan comparison

Cardiovascular disease and risk factors in Asia: a selected review

Cigarette smoking in middle age and a long-term risk of impaired activities of daily living: NIPPON DATA80.

Coffee and metabolic phenotypes: A cross-sectional analysis of the Japan multi-institutional collaborative cohort (J-MICC) study

Combined effect of weight gain within normal weight range and parental hypertension on the prevalence of hypertension; from the J-MICC Study

Detailed Analysis of Japanese Population Substructure with a Focus on the Southwest Islands of Japan ⬇️

Dietary sodium-to-potassium ratio as a risk factor for stroke, cardiovascular disease and all-cause mortality in Japan: the NIPPON DATA80 cohort study.

Dietary tofu intake and long-term risk of death from stroke in a general population

Differential effect of polymorphisms on body mass index across the life course of Japanese: the Japan Multi-Institutional Collaborative Cohort Study

Does the flushing response modify the relationship between alcohol intake and hypertension in the Japanese population? NIPPON DATA2010.

Effect of the PPARG2 Pro12Ala polymorphism and clinical risk factors for diabetes mellitus on HbA1c in the Japanese general population

Effects of self-reported calorie restriction on correlations between SIRT1 polymorphisms and body mass index and long-term weight change.

GCK, GCKR polymorphisms and risk of chronic kidney disease in Japanese individuals: data from the J-MICC Study.

Gene variants in PPARD and PPARGC1A are associated with timing of natural menopause in the general Japanese population

Genetic Predisposition to Ischemic Stroke: A Polygenic Risk Score

Genetic Variants of RAMP2 and CLR are Associated with Stroke.

Genetic variants of SLC17A1 are associated with cholesterol homeostasis and hyperhomocysteinaemia in Japanese men.

Genome-Wide Association Study of Renal Function Traits: Results from the Japan Multi-Institutional Collaborative Cohort Study

Genome-wide Association Study of Leisure-Time Exercise Behavior in Japanese Adults

Genome-wide association meta-analysis and Mendelian randomization analysis confirm ALDH2 influencing on sleep duration in the Japanese population

Genome-wide association study of genetic factors related to confectionery intake: Potential roles of theADIPOQgene

Genome-wide meta-analysis identifies multiple novel loci associated with serum uric acid levels in Japanese individuals

Impact of PSCA polymorphisms on the risk of duodenal ulcer

Increased Aortic Calcification Is Associated With Arterial Stiffness Progression in Multiethnic Middle-Aged Men.

Independent relationships of daily life activity and leisure-time exercise with metabolic syndrome and its traits in the general Japanese population

Interaction between dietary marine-derived n-3 fatty acids intake and J-point elevation on the risk of cardiac death: a 24-year follow-up of Japanese men.

Lipoprotein particle profiles compared with standard lipids in association with coronary artery calcification in the general Japanese population.

Lipoprotein-associated phospholipase A2 is related to risk of subclinical atherosclerosis but is not supported by Mendelian randomization analysis in a general Japanese population.

Long-chain n-3 polyunsaturated fatty acids intake and cardiovascular disease mortality risk in Japanese: a 24-year follow-up of NIPPON DATA80.

Long-term risk of BP values above normal for cardiovascular mortality

Low-carbohydrate diets and cardiovascular and total mortality in Japanese: a 29-year follow-up of NIPPON DATA80.

Macronutrient intakes and serum oestrogen, and interaction with polymorphisms in CYP19A1 and HSD17B1 genes: a cross-sectional study in postmenopausal Japanese women

Matrix metalloproteinase 9 gene polymorphisms are associated with a multiple family history of gastric cancer

Overweight or underweight and the risk of decline in activities of daily living in a 22-year cohort study of a Japanese sample.

Polymorphisms in CYP19A1, HSD17B1 and HSD17B2 genes and serum sex hormone level among postmenopausal Japanese women

Population attributable fraction of smoking and metabolic syndrome on cardiovascular disease mortality in Japan: a 15-year follow up of NIPPON DATA90.

Population-specific and trans-ancestry genome-wide analyses identify distinct and shared genetic risk loci for coronary artery disease

Pro-/anti-inflammatory cytokine gene polymorphisms and chronic kidney disease: a cross-sectional study

Profile of participants and genotype distributions of 108 polymorphisms in a cross-sectional study of associations of genotypes with lifestyle and clinical factors: a project in the Japan Multi-Institutional Collaborative Cohort (J-MICC) Study.

Relationship between non-high-density lipoprotein cholesterol and the long-term mortality of cardiovascular diseases: NIPPON DATA 90.

Secular trends of the impact of overweight and obesity on hypertension in Japan, 1980-2010.

Serum level of LOX-1 ligand containing ApoB is associated with increased carotid intima-media thickness in Japanese community-dwelling men, especially those with hypercholesterolemiaLOX-1 ligand and IMT in Japanese

Socioeconomic Status Associated With Urinary Sodium and Potassium Excretion in Japan: NIPPON DATA2010.

Subtype-specific gout susceptibility loci and enrichment of selection pressure on ABCG2 and ALDH2 identified by subtype genome-wide meta-analyses of clinically defined gout patients

The interaction between ABCA1 polymorphism and physical activity on the HDL-cholesterol levels in a Japanese population

The role of initial and longitudinal change in blood pressure on progression of arterial stiffness among multiethnic middle-aged men.

Transethnic Meta-analysis of Genome-wide Association Studies Identifies Three New Loci and Characterizes Population-specific Differences for Coronary Artery Disease

Variant of the clock circadian regulator (CLOCK) gene and related haplotypes are associated with the prevalence of type 2 diabetes in the Japanese population.