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List of works by Kole T Roybal

Beyond the TCR, Antigen Discrimination in T Cells Continues in the LAT:GRB2:SOS Protein Condensate

scholarly article

CRISPR-based screens uncover determinants of immunotherapy response in multiple myeloma

scientific article published on 01 July 2020

CRISPR/Cas9-mediated PD-1 disruption enhances anti-tumor efficacy of human chimeric antigen receptor T cells

scientific article

Clonal Deletion of Tumor-Specific T Cells by Interferon-γ Confers Therapeutic Resistance to Combination Immune Checkpoint Blockade

scientific article published on 05 February 2019

Computational spatiotemporal analysis identifies WAVE2 and cofilin as joint regulators of costimulation-mediated T cell actin dynamics

scientific article

DNA scaffolds enable efficient and tunable functionalization of biomaterials for immune cell modulation

scientific article published on 14 December 2020

Differential regulation of the period genes in striatal regions following cocaine exposure

scientific article (publication date: 2013)

Diminished cell proliferation promotes natural killer cell adaptive-like phenotype by limiting FcεRIγ expression

scientific article published in 2022

Early Signaling in Primary T Cells Activated by Antigen Presenting Cells Is Associated with a Deep and Transient Lamellal Actin Network

scientific article

Engineering Customized Cell Sensing and Response Behaviors Using Synthetic Notch Receptors

scientific article

Engineering T Cells with Customized Therapeutic Response Programs Using Synthetic Notch Receptors

scientific article published on 28 September 2016

Enhancement of anti-tumor CD8 immunity by IgG1-mediated targeting of Fc receptors.

scientific article published on January 2014

IFN-α suppresses GATA3 transcription from a distal exon and promotes H3K27 trimethylation of the CNS-1 enhancer in human Th2 cells

scientific article

IMMU-57. SEQUENTIAL TWO-RECEPTOR PRIMING CAR SYSTEM TO OVERCOME HETEROGENEOUS ANTIGEN EXPRESSION

article by Payal Watchmaker et al published 5 November 2018 in Neuro-Oncology

Inhibiting the Inhibitor of the Inhibitor: Blocking PKC-θ to Enhance Regulatory T Cell Function ⬇️

scientific article published on July 27, 2010

Mania-like behavior induced by disruption of CLOCK

scientific article

Modest Interference with Actin Dynamics in Primary T Cell Activation by Antigen Presenting Cells Preferentially Affects Lamellal Signaling

scientific article (publication date: 2015)

Multidimensional control of therapeutic human cell function with synthetic gene circuits

scientific article published on 16 December 2022

Mycobacterial shuttle vectors designed for high-level protein expression in infected macrophages

scientific article

New TACTICS for finding Numb

scientific article

NextGen cell-based immunotherapies in cancer and other immune disorders

scientific article published on 06 May 2019

Paving New Roads for CARs

scientific article published on 19 October 2019

Pooled Knockin Targeting for Genome Engineering of Cellular Immunotherapies

scientific article published on 15 April 2020

Precise T cell recognition programs designed by transcriptionally linking multiple receptors

scientific article published on 01 November 2020

Precision Tumor Recognition by T Cells With Combinatorial Antigen-Sensing Circuits

scientific article

Refining cell therapy

scientific article published on 08 March 2018

Remote control of therapeutic T cells through a small molecule-gated chimeric receptor.

scientific article

Spatiotemporal patterning during T cell activation is highly diverse

scientific article

Synthetic Immunology: Hacking Immune Cells to Expand Their Therapeutic Capabilities

scientific article

Synthetic biology approaches to engineer T cells

scientific article

Synthetic biology: at the crossroads of genetic engineering and human therapeutics—a Keystone Symposia report

scientific article published in 2021

Tentative and transient natural killer cell polarization balances the requirements for discriminatory recognition and cytolytic efficacy ⬇️

scientific article published on November 1, 2010

The CD3 ζ Subunit Contains a Phosphoinositide-Binding Motif That Is Required for the Stable Accumulation of TCR–CD3 Complex at the Immunological Synapse ⬇️

scientific article published on May 4, 2011

The actin-driven spatiotemporal organization of T-cell signaling at the system scale

scientific article

convertibleCARs: A chimeric antigen receptor system for flexible control of activity and antigen targeting

scientific article published on 09 June 2020

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