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List of works by Olaf Rötzschke

"Chemical analogues" of HLA-DM can induce a peptide-receptive state in HLA-DR molecules

scientific article published on 20 September 2004

A Co-culture Model of PBMC and Stem Cell Derived Human Nasal Epithelium Reveals Rapid Activation of NK and Innate T Cells Upon Influenza A Virus Infection of the Nasal Epithelium

article

A comprehensive association analysis confirms ZMIZ1 to be a susceptibility gene for vitiligo in Chinese population

scientific article published on 25 March 2014

A functional SNP associated with atopic dermatitis controls cell type-specific methylation of the VSTM1 gene locus

scientific article published on 20 February 2017

A functional brain-derived neurotrophic factor (BDNF) gene variant increases the risk of moderate-to-severe allergic rhinitis

scientific article

A pH-sensitive histidine residue as control element for ligand release from HLA-DR molecules

scientific article

Absence of leucine zipper in the natural FOXP3Delta2Delta7 isoform does not affect dimerization but abrogates suppressive capacity.

scientific article

Active Suppression Induced by Repetitive Self-Epitopes Protects against EAE Development ⬇️

scientific article published on May 30, 2013

Allele-specific motifs revealed by sequencing of self-peptides eluted from MHC molecules. 1991.

scientific article published in September 2006

Analysis of T Cell Subsets in Adult Primary/Idiopathic Minimal Change Disease: A Pilot Study.

scientific article published on 15 August 2017

Analysis of archaic human haplotypes suggest 5-hmC to act as epigenetic guide for meiotic point recombination

Anchor side chains of short peptide fragments trigger ligand-exchange of class II MHC molecules

scientific article

ArchiLD: hierarchical visualization of linkage disequilibrium in human populations

scientific article published on 21 January 2014

Are we ready for the use of foxp3(+) regulatory T cells for immunodiagnosis and immunotherapy in kidney transplantation?

scientific article published on 29 May 2012

Association of interleukin-13 SNP rs20541 (Arg>Gln) to allergic rhinitis in an Asian population of ethnic Chinese in Singapore

scientific article published on 15 August 2013

Atopic dermatitis microbiomes stratify into ecological dermotypes enabling microbial virulence and disease severity

scientific article published on 08 October 2020

Bidirectional binding of invariant chain peptides to an MHC class II molecule

scientific article

Biomarker Signatures Predicting 10-Year All-Cause and Disease-Specific Mortality

scientific article published on 01 March 2019

Bose-Einstein distribution, condensation transition, and multiple stationary states in multiloci evolution of diploid populations

scientific article published on 16 September 2010

CCR6 expression defines regulatory effector/memory-like cells within the CD25(+)CD4+ T-cell subset.

scientific article published on 21 December 2004

CD49d provides access to "untouched" human Foxp3+ Treg free of contaminating effector cells.

scientific article published on 21 October 2008

Cathepsin G, and not the asparagine-specific endoprotease, controls the processing of myelin basic protein in lysosomes from human B lymphocytes

scientific article

Cell Specific eQTL Analysis without Sorting Cells

scientific article published on 8 May 2015

Cell specific eQTL analysis without sorting cells

Characterization of structural features controlling the receptiveness of empty class II MHC molecules.

scientific article

Design of protease-resistant myelin basic protein-derived peptides by cleavage site directed amino acid substitutions

scientific article published on 2 August 2007

Differential IL-1β secretion by monocyte subsets is regulated by Hsp27 through modulating mRNA stability.

scientific article published on 15 December 2016

Discovery of six new susceptibility loci and analysis of pleiotropic effects in leprosy

scientific article published on 2 February 2015

Early neutralizing IgG response to Chikungunya virus in infected patients targets a dominant linear epitope on the E2 glycoprotein

scientific article

Establishing criteria for human mesenchymal stem cell potency

scientific article published on June 2015

Evaluation of the applicability of the Immuno-solid-phase allergen chip (ISAC) assay in atopic patients in Singapore

scientific article

Expanding Regulatory T Cells Alleviates Chikungunya Virus-Induced Pathology in Mice

scientific article

Expression of ectonucleotidase CD39 by Foxp3+ Treg cells: hydrolysis of extracellular ATP and immune suppression.

scientific article

Fine-mapping analysis revealed complex pleiotropic effect and tissue-specific regulatory mechanism of TNFSF15 in primary biliary cholangitis, Crohn's disease and leprosy

scientific article

Fingolimod treatment abrogates chikungunya virus–induced arthralgia

scientific article

Flipped CLIP orientation in the MHC class II binding groove

Functional variants of 17q12-21 are associated with allergic asthma but not allergic rhinitis

scientific article published on 16 October 2015

Genetic analysis of an allergic rhinitis cohort reveals an intercellular epistasis between FAM134B and CD39.

scientific article

Genetic variants of inducible costimulator are associated with allergic asthma susceptibility

scientific article published on 7 August 2014

Genome-wide analysis of the genetic regulation of gene expression in human neutrophils

scientific article published on 10 August 2015

Gut-Brain Axis: Potential Factors Involved in the Pathogenesis of Parkinson's Disease

scientific article published on 25 August 2020

Identification of new susceptibility loci for IgA nephropathy in Han Chinese.

scientific article published on June 2015

Immune Modulation and Prevention of Autoimmune Disease by Repeated Sequences from Parasites Linked to Self Antigens

scientific article published on 12 August 2016

Immune modulation of inflammatory conditions: regulatory T cells for treatment of GvHD ⬇️

scientific article published on September 1, 2012

In vivo-activated CD103+ Foxp3+ Tregs: of men and mice.

scientific article published in February 2009

Influenza A virus infection results in a robust, antigen-responsive, and widely disseminated Foxp3+ regulatory T cell response.

scientific article published on 28 December 2011

Inversed association of FCER1A allergy variant in monocytes and plasmacytoid dendritic cells

scientific article published on 05 November 2020

Large-scale Isolation of Highly Pure "Untouched" Regulatory T Cells in a GMP Environment for Adoptive Cell Therapy

scientific article published in July 2015

Ligand exchange of major histocompatibility complex class II proteins is triggered by H-bond donor groups of small molecules

scientific article

Multimerized T cell epitopes protect from experimental autoimmune diabetes by inducing dominant tolerance.

scholarly article

Network-based analysis reveals novel gene signatures in peripheral blood of patients with chronic obstructive pulmonary disease.

scientific article published on 24 April 2017

Neuropeptide Y associated with asthma in young adults.

scientific article published on 20 July 2016

Production of neuroprotective NGF in astrocyte-T helper cell cocultures is upregulated following antigen recognition

scientific article published in April 2004

Protein expression profiles of human lymph and plasma mapped by 2D-DIGE and 1D SDS–PAGE coupled with nanoLC–ESI–MS/MS bottom-up proteomics ⬇️

scientific article published on November 30, 2012

RNA Sequencing of H3N2 Influenza Virus-Infected Human Nasal Epithelial Cells from Multiple Subjects Reveals Molecular Pathways Associated with Tissue Injury and Complications

scientific article published on 27 August 2019

Regulatory T cells in transplantation: does extracellular adenosine triphosphate metabolism through CD39 play a crucial role?

scientific article published on 11 February 2010

Replication of genome-wide association study loci for allergic rhinitis and house dust mite sensitization in an Asian population of ethnic Chinese in Singapore

scientific article published on 8 December 2012

Resistin expression in human monocytes is controlled by two linked promoter SNPs mediating NFKB p50/p50 binding and C-methylation

scientific article published on 23 October 2019

Small organic compounds enhance antigen loading of class II major histocompatibility complex proteins by targeting the polymorphic P1 pocket

scientific article

Small-molecular compounds enhance the loading of APC with encephalitogenic MBP protein

scientific article published in February 2003

Systematic characterization of basophil anergy

scientific article

The final cut: how ERAP1 trims MHC ligands to size

scientific article

The lymph as a pool of self-antigens

scientific article published on December 2010

The role of IgA in COVID-19

scientific article published on 23 May 2020

Unraveling the polygenic architecture of complex traits using blood eQTL meta-analysis

scholarly article published 19 October 2018

Viral dynamics and immune correlates of COVID-19 disease severity

scientific article published on 28 August 2020

Virus infection drives IL-2 antibody complexes into pro-inflammatory agonists in mice

scientific article

Vδ2+ and α/ß T cells show divergent trajectories during human aging

scientific article published on 15 June 2016

Warburg metabolism in tumor-conditioned macrophages promotes metastasis in human pancreatic ductal adenocarcinoma.

scientific article published on 21 June 2016

Whole blood immunophenotyping uncovers immature neutrophil-to-VD2 T-cell ratio as an early marker for severe COVID-19

scientific article published on 16 October 2020

Whole-genome sequencing identifies responders to Pembrolizumab in relapse/refractory natural-killer/T cell lymphoma

scientific article published on 05 August 2020

XXIV World Allergy Congress 2015

scientific article (publication date: April 2016)

XXIV World Allergy Congress 2015: Seoul, Korea. 14-17 October 2015

scientific article published in 2016

γ/δ T cell subsets in human aging using the classical α/β T cell model

scientific article published on 7 July 2014

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