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List of works by Leonard Milstone

2,3,7,8-Tetrachlorodibenzo-p-dioxin induces hyperplasia in confluent cultures of human keratinocytes

scientific article published on 01 May 1984

502 The genomic and phenotypic landscape of ichthyosis: An analysis of 1000 kindreds

scientific article published in 2022

Aaron Lerner remembered

scientific article published in September 2007

Alterations in connexin 26 protein structure from lethal keratitis-ichthyosis-deafness syndrome mutations A88V and G45E

scientific article published on 10 July 2019

An appraisal of oral retinoids in the treatment of pachyonychia congenita.

scientific article published on 24 May 2011

Antiviral Activity of 5-Iodo-2’-Deoxyuridine and Related Drugs in Human Keratinocytes Infected in vitro with Herpes simplex Virus Type 1 ⬇️

scientific article published on January 1, 1991

Association of the Severity of Alopecia With the Severity of Ichthyosis

scientific article published on 31 July 2019

Barrier dysfunction and pathogenesis of neutral lipid storage disease with ichthyosis (Chanarin-Dorfman syndrome).

scientific article

Bone densities in patients receiving isotretinoin for cystic acne

scientific article published on 01 August 1999

CARD14-associated papulosquamous eruption: A spectrum including features of psoriasis and pityriasis rubra pilaris.

scientific article published on 22 February 2018

CD44 expression on epidermal melanocytes

scientific article published on 01 June 1996

Changing concepts of keratin

scientific article published on 01 January 1980

Characterization of a parathyroid hormonelike peptide secreted by human keratinocytes

scientific article published in January 1988

Classification and therapy of atrophie blanche

scientific article published on December 1983

Clinical and pathological features of pachyonychia congenita

scientific article

Connexin channels in congenital skin disorders.

scientific article

Consensus recommendations for the use of retinoids in ichthyosis and other disorders of cornification in children and adolescents

scientific article published on 10 November 2020

Crystal Structure of Human Profilaggrin S100 Domain and Identification of Target Proteins Annexin II, Stratifin, and HSP27.

scientific article published on 11 March 2015

Delayed-onset pachyonychia congenita associated with a novel mutation in the central 2B domain of keratin 16.

scientific article

Dermatosparaxis in children. A case report and review of the newly recognized phenotype

scientific article

Development of quantitative molecular clinical end points for siRNA clinical trials

scientific article

Development or worsening of sarcoidosis associated with IL-17 blockade for psoriasis

scientific article published on 11 April 2020

Diagnosis of autosomal recessive lamellar ichthyosis with mutations in the TGM1 gene

scientific article published on 01 April 2001

Dipyridamole potentiates the growth-inhibitory action of methotrexate and 5-fluorouracil in human keratinocytes in vitro

scientific article published on 01 October 1989

Effector functions of epidermal keratinocytes

scientific article published on 01 January 1988

Epican, a heparan/chondroitin sulfate proteoglycan form of CD44, mediates cell-cell adhesion.

scientific article published on November 1994

Epidermal cell confluence and implications for a two-step mechanism of wound closure

scientific article published on December 1984

Epidermal desquamation

scientific article

Establishing and Validating an Ichthyosis Severity Index.

scientific article published on 5 June 2017

Expanding the Genotypic Spectrum of Bathing Suit Ichthyosis.

scientific article

Expanding the Phenotypic Spectrum of Olmsted Syndrome

scientific article published on 12 June 2015

First-in-human mutation-targeted siRNA phase Ib trial of an inherited skin disorder.

scientific article

Frequent somatic reversion of KRT1 mutations in ichthyosis with confetti.

scientific article

GABA from putrescine is bound in macromolecular form in keratinocytes

scientific article published on 01 August 1983

Gene expression profiling in pachyonychia congenita skin

scientific article

Gene therapy for autosomal dominant disorders of keratin.

scientific article

Generalized linear porokeratosis treated with etretinate

scientific article published on 01 April 1995

Glycosylation of parathyroid hormone-related peptide secreted by human epidermal keratinocytes

scientific article published in November 1991

Growth and differentiation regulate CD44 expression on human keratinocytes

scientific article published on April 1999

Harlequin ichthyosis: neonatal management and identification of a new ABCA12 mutation

scientific article

Heterogeneity of basal keratinocytes: nonrandom distribution of thymidine-labeled basal cells in confluent cultures is not a technical artifact

scientific article published on June 1985

Human keratinocytes catabolize thymidine

scientific article published on 01 January 1988

IL-17 blockade downregulates NOD2 in skin and may promote paradoxical sarcoidosis

scientific article published on 06 April 2020

Identification and characterization of a cell surface proteoglycan on keratinocytes

scientific article published on 01 October 1992

Imaging Functional Nucleic Acid Delivery to Skin

scientific article

Immunoaffinity purification of parathyroid hormone-related protein from bovine milk and human keratinocyte-conditioned medium

scientific article published on 01 March 1991

Immunohistochemical localization of parathyroid hormone-related protein (PTHRP) in normal human skin

scientific article published on 01 February 1991

Impact of epidermal desquamation on tissue stores of iron

scientific article

Improving outcomes for harlequin ichthyosis

scientific article

In vivo fluorescence of human skin. A potential marker of photoaging

scientific article

Incidence of moderate to severe ichthyosis in the United States

scientific article published on 01 September 2012

Inhibition of CD44 gene expression in human skin models, using self-delivery short interfering RNA administered by dissolvable microneedle arrays

scientific article

Iron in skin of mice with three etiologies of systemic iron overload.

scientific article

Is retinoid-induced osteopenia reversible?

scientific article published in November 2002

Isotretinoin does have an adverse effect on bone mineral density.

scientific article published in July 2005

Keratinocytes differentiate in response to inhibitors of deoxyribonucleotide synthesis

scientific article published on 01 March 1995

Keratins in cultivated human keratinocytes are stable

scientific article published on 01 January 1980

Local and systemic implications of thymidine catabolism by human keratinocytes

scientific article published on 01 January 1988

Local delivery of gene-modifying triplex-forming molecules to the epidermis

scientific article

Long-term murine keratinocyte cultures become tetraploid, yet maintain the ability to stratify

scientific article published on 01 August 2004

Management of ichthyosis and related conditions gene-based diagnosis and emerging gene-based therapy

scientific article published on January 2013

Meeting report from Frontiers in Ichthyosis Research.

scientific article

Methotrexate induces differentiation of human keratinocytes ⬇️

scientific article published on January 15, 1992

Mitotic recombination in patients with ichthyosis causes reversion of dominant mutations in KRT10

scientific article

More than keratitis, ichthyosis, and deafness: multisystem effects of lethal GJB2 mutations

scientific article published on 02 October 2018

Mutations in PERP cause dominant and recessive keratoderma

scientific article published on 12 October 2018

Mutations in TGM1 in Ecuadorians with autosomal recessive congenital ichthyosis

scientific article published on 21 November 2013

Nail removal in pachyonychia congenita: Patient-reported survey outcomes.

scientific article published in May 2017

Native and a synthetic analogue of the malignancy-associated parathyroid hormone-like protein have in vitro transforming growth factor-like properties

scientific article

Obstacles to translation conference

scientific article published in July 2006

PURPLE (oops! Atrophie blanche) revisited

scientific article published on 01 December 1998

Palmoplantar Keratoderma in Costello Syndrome Responsive to Acitretin.

scientific article published on 23 December 2016

Parathyroid hormone-related protein. Evidence for secretion of a novel mid-region fragment by three different cell types

scientific article published on September 1992

Phenotypic expansion in ichthyosis with confetti

scientific article published on 01 January 2015

Phenotypic spectrum of autosomal recessive congenital ichthyosis due to PNPLA1 mutation.

scientific article published on 12 April 2017

Photodegraded nifedipine stimulates uptake and retention of iron in human epidermal keratinocytes

scientific article

Pneumocystis carinii pneumonia complicating methotrexate treatment of pityriasis rubra pilaris

scientific article published on 01 August 1998

Population dynamics in cultures of stratified squamous epithelia

scientific article published on 01 July 1983

Premature epiphyseal closure in a child receiving oral 13-cis-retinoic acid

scientific article

Prescribing retinoids. The art and the science

scientific article published on 01 July 1986

Quantitation of cross-linked protein: An alternative to counting cornified envelopes as an index of keratinocyte differentiation ⬇️

scientific article published on November 15, 1991

Recurrent Coxsackievirus Infection in a Patient with Lamellar Ichthyosis

scientific article published on 29 January 2016

Report of the 10th Annual International Pachyonychia Congenita Consortium Meeting

scientific article

Response of stratified cultures of human keratinocytes to disruption of proteoglycan synthesis by p-nitrophenyl-beta-D-xylopyranoside

scientific article

Retinoic acid causes premature desquamation of cells from confluent cultures of stratified squamous epithelia

scientific article published on 01 October 1982

Revised nomenclature and classification of inherited ichthyoses: results of the First Ichthyosis Consensus Conference in Sorèze 2009.

scientific article

Scaly skin and bath pH: rediscovering baking soda

scientific article published in May 2010

Secondary hyperparathyroidism in patients with ichthyosis is not caused by vitamin D deficiency or ingestion of retinoids

scientific article published on 01 May 1993

Serum parathyroid hormone level is elevated in some patients with disorders of keratinization

scientific article published on 01 July 1992

Single-nucleotide-specific siRNA targeting in a dominant-negative skin model

scientific article

Skin potions

scientific article published on 01 August 1987

Skin-derived fibroblasts respond to human parathyroid hormone-like adenylate cyclase-stimulating proteins.

scientific article

Stratum-specific expression of human transferrin receptor increases iron in mouse epidermis.

scientific article published in March 2006

Systemic retinoids in the management of ichthyoses and related skin types.

scientific article published on January 2013

The Core Protein of Epican, a Heparan Sulfate Proteoglycan on Keratinocytes, Is an Alternative Form of CD44 ⬇️

scientific article published on December 1, 1992

The Protein Acyl Transferase ZDHHC21 Modulates α1 Adrenergic Receptor Function and Regulates Hemodynamics

scientific article published on 29 December 2015

The X-Ray Crystal Structure of the Keratin 1-Keratin 10 Helix 2B Heterodimer Reveals Molecular Surface Properties and Biochemical Insights into Human Skin Disease.

scientific article

The influence of retinoids on cultivated human keratinocytes ⬇️

scientific article published on 01 April 1982

Therapeutic siRNAs for dominant genetic skin disorders including pachyonychia congenita.

scientific article published on 20 May 2008

Thymidine phosphorylase in human epidermal keratinocytes

scientific article published on 01 January 1988

Topical tazarotene for the treatment of ectropion in ichthyosis

scientific article published on May 2013

Treatment of pachyonychia congenita.

scientific article

Two distinct tumor-derived, parathyroid hormone-like peptides result from alternative ribonucleic acid splicing

scientific article

Use of telemedicine for ichthyosis: Patient advocacy group as conduit to expert physician advice

scientific article published on 23 November 2020

Visualization of plasmid delivery to keratinocytes in mouse and human epidermis

scientific article published on 15 November 2011

Well-Differentiated Syringofibrocarcinoma in a Patient With Clouston Syndrome.

scientific article published in April 2016

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