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List of works by Gregory A. Light

124. Experimental Medicine Approaches to Leveraging Auditory Information Processing Neuroplasticity Toward Therapeutic Development in Schizophrenia.

scientific article

80. Auditory Target Processing Deficits in Individuals at Clinical High Risk for Psychosis.

scientific article

Abnormal Effective Connectivity Underlying Auditory Mismatch Negativity Impairments in Schizophrenia

scientific article published on 05 June 2020

Abnormal Spontaneous Gamma Power Is Associated With Verbal Learning and Memory Dysfunction in Schizophrenia

scientific article published on 31 August 2020

Abnormal auditory N100 amplitude: a heritable endophenotype in first-degree relatives of schizophrenia probands

scientific article

Advances in endophenotyping schizophrenia

scientific article

Amphetamine Enhances Gains in Auditory Discrimination Training in Adult Schizophrenia Patients

scientific article

Analysis of 94 candidate genes and 12 endophenotypes for schizophrenia from the Consortium on the Genetics of Schizophrenia

scientific article

Animal Models of Deficient Sensorimotor Gating in Schizophrenia: Are They Still Relevant?

scientific article published on 17 June 2016

Antisaccade performance in schizophrenia patients, their first-degree biological relatives, and community comparison subjects: data from the COGS study

scientific article

Association Between P300 Responses to Auditory Oddball Stimuli and Clinical Outcomes in the Psychosis Risk Syndrome

scientific article published on 07 August 2019

Association analysis of 94 candidate genes and schizophrenia-related endophenotypes

scientific article

Attention/vigilance in schizophrenia: performance results from a large multi-site study of the Consortium on the Genetics of Schizophrenia (COGS).

scientific article

Automatic sensory information processing abnormalities across the illness course of schizophrenia ⬇️

scientific article published on July 11, 2011

Bending the curve on psychosis outcomes

scientific article published on 28 April 2015

Between-site reliability of startle prepulse inhibition across two early psychosis consortia

scientific article

California Verbal Learning Test-II performance in schizophrenia as a function of ascertainment strategy: comparing the first and second phases of the Consortium on the Genetics of Schizophrenia (COGS).

scientific article published on 12 December 2014

Characterization of neurophysiologic and neurocognitive biomarkers for use in genomic and clinical outcome studies of schizophrenia

scientific article

Comparison of the heritability of schizophrenia and endophenotypes in the COGS-1 family study

scientific article

Computerized cognitive training is associated with improved psychosocial treatment engagement in schizophrenia

scientific article published on 19 June 2018

Contextualizing the road to recovery: A novel method of assessing outcome trajectories in clinical trials

scientific article published on 13 July 2020

Convergence and divergence in the neurochemical regulation of prepulse inhibition of startle and N40 suppression in rats

scientific article

Correction to: Electrophysiological biomarkers of behavioral dimensions from cross-species paradigms

scientific article published in 2022

Cortical substrates and functional correlates of auditory deviance processing deficits in schizophrenia

scientific article

Cross-Species Neurophysiological Biomarkers of Attentional Dysfunction in Schizophrenia: Bridging the Translational Gap.

scientific article

Decreased Gamma Auditory Steady-State Response Is Associated With Impaired Real-World Functioning in Unmedicated Patients at Clinical High Risk for Psychosis

scientific article published on 23 December 2020

Deficient prepulse inhibition in schizophrenia detected by the multi-site COGS.

scientific article

Deficient prepulse inhibition in schizophrenia in a multi-site cohort: Internal replication and extension

scientific article published on 23 May 2017

Deficits in auditory predictive coding in individuals with the psychosis risk syndrome: Prediction of conversion to psychosis

scientific article published on 01 August 2020

Demand and modality of directed attention modulate "pre-attentive" sensory processes in schizophrenia patients and nonpsychiatric controls

scientific article

Disentangling early sensory information processing deficits in schizophrenia

scientific article

Divergence of subjective and performance-based cognitive gains following cognitive training in schizophrenia

scientific article published on 16 January 2019

Effects of acute memantine administration on MATRICS Consensus Cognitive Battery performance in psychosis: Testing an experimental medicine strategy

scientific article

Effects of olanzapine, risperidone and haloperidol on prepulse inhibition in schizophrenia patients: a double-blind, randomized controlled trial

scientific article

Electroencephalographic biomarkers of psychosis: present and future

scientific article published on January 2015

Electroencephalography (EEG) and event-related potentials (ERPs) with human participants

scientific article

Event-related gamma activity in schizophrenia patients during a visual backward-masking task

scientific article published in December 2005

Evidence of Slow Neural Processing, Developmental Differences and Sensitivity to Cannabis Effects in a Sample at Clinical High Risk for Psychosis From the NAPLS Consortium Assessed With the Human Startle Paradigm

scientific article published on 25 August 2020

Evidence of systematic attenuation in the measurement of cognitive deficits in schizophrenia

scientific article published on 9 March 2017

F118. ARCHITECTURE OF PSYCHOSIS SYMPTOMS AND NEURAL PREDICTORS OF CONVERSION AMONG CLINICAL HIGH RISK INDIVIDUALS WITH AUTISM SPECTRUM DISORDER.

scientific article

Factor structure and heritability of endophenotypes in schizophrenia: findings from the Consortium on the Genetics of Schizophrenia (COGS-1).

scientific article published on 11 February 2015

Female schizophrenia patients have prepulse inhibition deficits

scientific article published in April 2005

Forebrain gene expression predicts deficits in sensorimotor gating after isolation rearing in male rats

scientific article

Fronto-temporal-mesolimbic gene expression and heritable differences in amphetamine-disrupted sensorimotor gating in rats.

scientific article

Future clinical uses of neurophysiological biomarkers to predict and monitor treatment response for schizophrenia

scientific article

Gamma band oscillations reveal neural network cortical coherence dysfunction in schizophrenia patients.

scientific article published on 7 August 2006

Gamma oscillations predict pro-cognitive and clinical response to auditory-based cognitive training in schizophrenia

scientific article published on 23 November 2020

Gating Deficit Heritability and Correlation With Increased Clinical Severity in Schizophrenia Patients With Positive Family History

scientific article

Genetic assessment of additional endophenotypes from the Consortium on the Genetics of Schizophrenia Family Study.

scientific article

Genome-wide Association of Endophenotypes for Schizophrenia From the Consortium on the Genetics of Schizophrenia (COGS) Study

scientific article published on 09 October 2019

Genome-wide linkage analyses of 12 endophenotypes for schizophrenia from the Consortium on the Genetics of Schizophrenia

scientific article

GlyT-1 Inhibition Attenuates Attentional But Not Learning or Motivational Deficits of the Sp4 Hypomorphic Mouse Model Relevant to Psychiatric Disorders

scientific article

Group and site differences on the California Verbal Learning Test in persons with schizophrenia and their first-degree relatives: findings from the Consortium on the Genetics of Schizophrenia (COGS).

scientific article published in February 2011

Heritability of acoustic startle magnitude and latency from the consortium on the genetics of schizophrenia

scientific article published on 11 November 2020

Hierarchical Pathways from Sensory Processing to Cognitive, Clinical, and Functional Impairments in Schizophrenia

scientific article published on 28 August 2020

Hierarchical organization of gamma and theta oscillatory dynamics in schizophrenia

scientific article

How Shared Is Shared Decision Making? Reaching the Full Potential of Patient-Clinician Collaboration in Mental Health

scientific article published on 5 August 2021

Impaired Sensory Processing During Low-Oxygen Exposure: A Noninvasive Approach to Detecting Changes in Cognitive States

scientific article published on 31 January 2020

Inhibition of the P50 cerebral evoked response to repeated auditory stimuli: results from the Consortium on Genetics of Schizophrenia

scientific article published on 10 April 2010

Initial heritability analyses of endophenotypic measures for schizophrenia: the consortium on the genetics of schizophrenia

scientific article

Is there an association between advanced paternal age and endophenotype deficit levels in schizophrenia?

scientific article

Mapping genomic loci implicates genes and synaptic biology in schizophrenia

scientific article published on 8 April 2022

Measuring P50 Suppression and Prepulse Inhibition in a Single Recording Session ⬇️

scientific article published on December 1, 2001

Measuring the capacity for auditory system plasticity: An examination of performance gains during initial exposure to auditory-targeted cognitive training in schizophrenia

scientific article published on 02 February 2016

Memantine Effects On Sensorimotor Gating and Mismatch Negativity in Patients with Chronic Psychosis.

scientific article

Memantine Effects on Electroencephalographic Measures of Putative Excitatory/Inhibitory Balance in Schizophrenia

scientific article published on 22 February 2020

Mismatch Negativity is a Sensitive and Predictive Biomarker of Perceptual Learning During Auditory Cognitive Training in Schizophrenia

scientific article published on 31 January 2017

Mismatch negativity deficits are associated with poor functioning in schizophrenia patients

scientific article published in February 2005

Mismatch negativity impairment is associated with deficits in identifying real-world environmental sounds in schizophrenia.

scientific article published on 15 September 2017

Mismatch negativity reveals plasticity in cortical dynamics after 1-hour of auditory training exercises

scientific article published on 06 June 2019

Modeling Deficits From Early Auditory Information Processing to Psychosocial Functioning in Schizophrenia

scientific article published on 7 December 2016

Multi-site studies of acoustic startle and prepulse inhibition in humans: initial experience and methodological considerations based on studies by the Consortium on the Genetics of Schizophrenia

scientific article

Neural network dynamics underlying gamma synchronization deficits in schizophrenia

scientific article published on 16 December 2020

Neural substrates of normal and impaired preattentive sensory discrimination in large cohorts of nonpsychiatric subjects and schizophrenia patients as indexed by MMN and P3a change detection responses.

scientific article

Neurobiological measures of schizotypal personality disorder: defining an inhibitory endophenotype?

scientific article

Neurocognitive performance in family-based and case-control studies of schizophrenia

scientific article published on April 2015

Neurophysiologic Characterization of Resting State Connectivity Abnormalities in Schizophrenia Patients

scientific article published on 27 November 2020

Neurophysiologic markers of abnormal brain activity in schizophrenia

scientific article

Neurophysiologic measures of target engagement predict response to auditory-based cognitive training in treatment refractory schizophrenia

scientific article published on 30 October 2018

Neurophysiological Characterization of Attentional Performance Dysfunction in Schizophrenia Patients in a Reverse-Translated Task

scientific article

Neurophysiological biomarkers informing the clinical neuroscience of schizophrenia: mismatch negativity and prepulse inhibition of startle

scientific article published in January 2014

Neurophysiological endophenotypes of schizophrenia: the viability of selected candidate measures

scientific article

Neurophysiological measures of sensory registration, stimulus discrimination, and selection in schizophrenia patients

scientific article published on January 2010

Nonlinear dynamics underlying sensory processing dysfunction in schizophrenia

scientific article published on 11 February 2019

Older Patients With Schizophrenia: Does Military Veteran Status Matter? ⬇️

scientific article published on March 1, 2012

On the waveform of the acoustic startle blink in the paradigm of prepulse inhibition - methodological and physiological aspects.

scientific article published on 3 June 2005

Oscillatory biomarkers of early auditory information processing predict cognitive gains following targeted cognitive training in schizophrenia patients

scientific article published on 20 November 2019

P50 suppression in individuals at risk for schizophrenia: the convergence of clinical, familial, and vulnerability marker risk assessment

scientific article published in June 2005

Paternal age of schizophrenia probands and endophenotypic differences from unaffected siblings

scientific article

Preattentional and attentional cognitive deficits as targets for treating schizophrenia

scientific article published on 30 April 2004

Preattentive sensory processing as indexed by the MMN and P3a brain responses is associated with cognitive and psychosocial functioning in healthy adults

scientific article

Prepulse inhibition and P50 suppression are both deficient but not correlated in schizophrenia patients

scientific article published on 8 December 2006

Prepulse inhibition of perceived stimulus intensity: paradigm assessment

scientific article published in May 2005

Prioritizing schizophrenia endophenotypes for future genetic studies: An example using data from the COGS-1 family study

scientific article

Realistic expectations of prepulse inhibition in translational models for schizophrenia research

scientific article

Reduced multisensory integration in patients with schizophrenia on a target detection task

scientific article

Relationship between effortful motivation and neurocognition in schizophrenia

scientific article published on 30 June 2017

Relationships between cognitive event-related brain potential measures in patients at clinical high risk for psychosis

scientific article published on 22 January 2019

Reliability of mismatch negativity event-related potentials in a multisite, traveling subjects study

scientific article published on 22 October 2020

Reverse translated and gold standard continuous performance tests predict global cognitive performance in schizophrenia

scientific article published on 12 April 2018

Robust differences in antisaccade performance exist between COGS schizophrenia cases and controls regardless of recruitment strategies

scientific article

Room to move: Plasticity in early auditory information processing and auditory learning in schizophrenia revealed by acute pharmacological challenge.

scientific article published on 4 April 2018

SA34. Schizophrenia Patients May Invest Suboptimal Effort due to Poor Performance Insight.

scientific article

SA62. The Auditory Brainstem Response to Complex Sounds (cABR) Indexes Cognitive Network Function in Schizophrenia.

scientific article

SU62. The 40-Hz Auditory Steady-State Response: A Sensitive and Predictive Biomarker of Perceptual Learning During Cognitive Training.

scientific article published on 20 March 2017

Selection criteria for neurophysiologic biomarkers to accelerate the pace of CNS therapeutic development

scientific article published on 01 January 2020

Sensitization and habituation of the acoustic startle reflex in patients with schizophrenia

scientific article published in April 2004

Sensorimotor gating deficits in schizophrenia: Advancing our understanding of the phenotype, its neural circuitry and genetic substrates

scientific article published on 07 March 2018

Sensory and sensorimotor gating deficits after neonatal ventral hippocampal lesions in rats

scientific article published on 8 May 2012

Sensory and sensorimotor gating-disruptive effects of apomorphine in Sprague Dawley and Long Evans rats

scientific article

Sex differences in familiality effects on neurocognitive performance in schizophrenia

scientific article published on 08 February 2013

Stability of mismatch negativity deficits and their relationship to functional impairments in chronic schizophrenia

scientific article

Stability of mismatch negativity event-related potentials in a multisite study

scientific article published on 30 March 2020

Startle gating deficits in a large cohort of patients with schizophrenia: relationship to medications, symptoms, neurocognition, and level of function

scientific article

Successful multi-site measurement of antisaccade performance deficits in schizophrenia

scientific article published on 3 October 2006

Superior size-weight illusion performance in patients with schizophrenia: evidence for deficits in forward models

scientific article

Targeted cognitive training improves auditory and verbal outcomes among treatment refractory schizophrenia patients mandated to residential care

scientific article published on 25 July 2018

The 5-choice continuous performance test: evidence for a translational test of vigilance for mice

scientific article

The Consortium on the Genetics of Endophenotypes in Schizophrenia: model recruitment, assessment, and endophenotyping methods for a multisite collaboration

scientific article

The auditory brain-stem response to complex sounds: a potential biomarker for guiding treatment of psychosis

scientific article

The effects of age and sex on cognitive impairment in schizophrenia: Findings from the Consortium on the Genetics of Schizophrenia (COGS) study

scientific article published on 13 May 2020

The relationship between preattentive sensory processing deficits and age in schizophrenia patients

scientific article

The use of neurophysiological endophenotypes to understand the genetic basis of schizophrenia.

scientific article published on January 2005

The utility of P300 as a schizophrenia endophenotype and predictive biomarker: clinical and socio-demographic modulators in COGS-2

scientific article

The “incredible shrinking” P50 event-related potential ⬇️

scientific article published on June 15, 1998

Tolcapone-Enhanced Neurocognition in Healthy Adults: Neural Basis and Predictors

scientific article

Using EEG-Guided Basket and Umbrella Trials in Psychiatry: A Precision Medicine Approach for Cognitive Impairment in Schizophrenia

scholarly article by Yash B Joshi & Gregory A Light published 2018 in Frontiers in Psychiatry

Validation of mismatch negativity and P3a for use in multi-site studies of schizophrenia: characterization of demographic, clinical, cognitive, and functional correlates in COGS-2.

scientific article

Verbal learning deficits associated with increased anticholinergic burden are attenuated with targeted cognitive training in treatment refractory schizophrenia patients

scientific article published on 06 February 2019

Verbal working memory impairments in individuals with schizophrenia and their first-degree relatives: findings from the Consortium on the Genetics of Schizophrenia

scientific article published on 11 April 2008

Verbal working memory in schizophrenia from the Consortium on the Genetics of Schizophrenia (COGS) study: the moderating role of smoking status and antipsychotic medications

scientific article

Visual masking as a probe for abnormal gamma range activity in schizophrenia

scientific article published in June 2003

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