List of works by Richard John Kryscio

"End-stage" neurofibrillary tangle pathology in preclinical Alzheimer's disease: fact or fiction?

scientific article

"New Old Pathologies": AD, PART, and Cerebral Age-Related TDP-43 With Sclerosis (CARTS).

scientific article published on 21 May 2016

A cognitive electrophysiological signature differentiates amnestic mild cognitive impairment from normal aging

scientific article published on 19 January 2017

A comparison of time-homogeneous Markov chain and Markov process multi-state models

A morphology index based on sonographic findings in ovarian cancer

scientific article published on 01 October 1993

A nonstationary Markov transition model for computing the relative risk of dementia before death

scientific article

A phase I trial of neutron brachytherapy for the treatment of malignant gliomas

scientific article published in November 1997

A randomized controlled Alzheimer's disease prevention trial's evolution into an exposure trial: the PREADViSE Trial

scientific article published on January 2013

A randomized trial of surgery in the treatment of single metastases to the brain

scientific article

A review of californium-252 neutron brachytherapy for cervical cancer

scientific article published on September 1991

ABCC9 gene polymorphism is associated with hippocampal sclerosis of aging pathology

scientific article

Acetylcholinesterase inhibitor treatment is associated with relatively slow cognitive decline in patients with Alzheimer's disease and AD + DLB

scientific article published on January 2009

Adjusting for mortality when identifying risk factors for transitions to mild cognitive impairment and dementia

scientific article published on January 2013

Adjuvant oral alkylating chemotherapy in patients with stage I epithelial ovarian cancer

scientific article published on 01 March 1989

Age-expanded normative data for the Ruff 2&7 Selective Attention Test: evaluating cognition in older males

scientific article

Altered brain activation in cognitively intact individuals at high risk for Alzheimer's disease

scientific article published on 01 October 1999

Alzheimer's Biomarkers are Correlated with Brain Connectivity in Older Adults Differentially during Resting and Task States.

scientific article published on 8 February 2016

Alzheimer's disease and head circumference

scientific article

Alzheimer's disease is not "brain aging": neuropathological, genetic, and epidemiological human studies

scientific article

Alzheimer's-type neuropathology in the precuneus is not increased relative to other areas of neocortex across a range of cognitive impairment

scientific article

Analysis of factors influencing the development of xerostomia during intensity-modulated radiotherapy

scientific article published on 22 March 2013

Are Markov and semi-Markov models flexible enough for cognitive panel data?

scientific article

Arteriolosclerosis that affects multiple brain regions is linked to hippocampal sclerosis of ageing

scientific article

Assessing the discriminant ability, reliability, and comparability of multiple short forms of the Boston Naming Test in an Alzheimer's disease center cohort

scientific article

Association between male gender and cortical Lewy body pathology in large autopsy series

scientific article

Association of Antioxidant Supplement Use and Dementia in the Prevention of Alzheimer's Disease by Vitamin E and Selenium Trial (PREADViSE).

scientific article published on 20 March 2017

Association of HFE mutations with neurodegeneration and oxidative stress in Alzheimer's disease and correlation with APOE

scientific article published on May 15, 2003

Association of smoking and chronic pain syndromes in Kentucky women

scientific article

Author Response

scientific article published on 01 June 2015

Autoantibodies to amyloid beta-peptide (Abeta) are increased in Alzheimer's disease patients and Abeta antibodies can enhance Abeta neurotoxicity: implications for disease pathogenesis and vaccine development

scientific article published on January 2003

Autologous dendritic cell vaccines for non-small-cell lung cancer.

scientific article published on July 2004

Aβ vaccination in combination with behavioral enrichment in aged beagles: effects on cognition, Aβ, and microhemorrhages

scientific article published on 26 September 2016

Baseline subjective memory complaints associate with increased risk of incident dementia: the PREADVISE trial

scientific article published in March 2015

Birth seasonality in a Rural U.S. county, 1911-1979.

scientific article published in January 1990

Bone remodeling biomarkers of periodontal disease in saliva

scientific article published on 01 October 2008

Bone remodeling-associated salivary biomarker MIP-1α distinguishes periodontal disease from health

scientific article published on 29 November 2011

Brain pathologies in extreme old age.

scientific article

Brain structure changes over time in normal and mildly impaired aged persons

scientific article published on 20 May 2020

Brains with medial temporal lobe neurofibrillary tangles but no neuritic amyloid plaques are a diagnostic dilemma but may have pathogenetic aspects distinct from Alzheimer disease.

scientific article published in July 2009

CERAD practice effects and attrition bias in a dementia prevention trial

scientific article

Calcium Channel Blockers, Progression to Dementia, and Effects on Amyloid Beta Peptide Production

scientific article published on 28 June 2015

Cancer history associates with a lower burden of dementia and Alzheimer’s‐type neuropathology in autopsied research volunteers

scientific article published in 2021

Changes in cognition and amyloid-β processing with long term cholesterol reduction using atorvastatin in aged dogs.

scientific article published on January 2010

Cholesterol and cognitive performance in normal controls and the influence of elective statin use after conversion to mild cognitive impairment: results in a clinical trial cohort

scientific article

Clinical evaluation of 252Cf neutron intracavitary therapy for primary endometrial adenocarcinoma

scientific article

Clinical implications of a rising serum CA-125 within the normal range in patients with epithelial ovarian cancer: a preliminary investigation☆

scientific article published on 01 May 2003

Continuing participation supports ultrasound screening for ovarian cancer

scientific article published on 01 May 2000

Contribution of BRCA1 and BRCA2 to familial ovarian cancer: a gynecologic oncology group study

scientific article published on 01 May 2002

Critical decline in fine motor hand movements in human aging

scientific article published on 01 October 1999

Cure of cervical cancer using 252Cf neutron brachytherapy

scientific article published in May 1990

Cytosolic phospholipase A2 is a key regulator of blood-brain barrier function in epilepsy

scientific article published on 29 October 2019

Designing a Brief Alzheimer Screen (BAS).

scientific article published in October 2003

Designing a large prevention trial: statistical issues.

scientific article published in January 2004

Diabetes is associated with cerebrovascular but not Alzheimer's disease neuropathology

scientific article published on 23 January 2016

Diabetes mitigates the role of memory complaint in predicting dementia risk: Results from the Prevention of Alzheimer's Disease with Vitamin E and Selenium Study

scientific article published on 7 March 2017

Diagnostic accuracy and practice effects in the National Alzheimer's Coordinating Center Uniform Data Set neuropsychological battery

scientific article

Differences in functional magnetic resonance imaging activation by category in a visual confrontation naming task

scientific article published on April 2001

Disease-related microglia heterogeneity in the hippocampus of Alzheimer's disease, dementia with Lewy bodies, and hippocampal sclerosis of aging

scientific article published on 23 May 2015

Distinct clinicopathologic clusters of persons with TDP-43 proteinopathy

scientific article published on 14 August 2020

Dopaminergic Modulation of Medial Prefrontal Cortex Deactivation in Parkinson Depression

scientific article

Dopaminergic modulation of memory and affective processing in Parkinson depression

scientific article published on 06 July 2013

Dosing and safety of cyclosporine in patients with severe brain injury

scientific article published on October 2008

Dysregulation of leptin signaling in Alzheimer disease: evidence for neuronal leptin resistance

scientific article published on 21 August 2013

Effect of common neuropathologies on progression of late life cognitive impairment

scientific article published on 22 April 2015

Effect of prophylactic valacyclovir on the presence of human herpesvirus DNA in saliva of healthy individuals after dental treatment

scientific article

Effects of ignoring baseline on modeling transitions from intact cognition to dementia

scientific article published on July 2009

Endometrioid carcinoma of the ovary and endometriosis: the association in postmenopausal women

scientific article published on October 1, 1992

Estimation of Multi-state Models with Missing Covariate Values Based on Observed Data Likelihood

scientific article published on 29 December 2018

Estimation of the rate of tooth wear in permanent incisors: a cross-sectional digital radiographic study

scientific article published on 10 March 2015

Evaluating trajectories of episodic memory in normal cognition and mild cognitive impairment: Results from ADNI

scientific article published on 25 February 2019

Feasibility study of Californium-252 for the therapy of stage IV cervical cancer

scientific article published on 01 June 1988

Frequency and disposition of ovarian abnormalities followed with serial transvaginal ultrasonography

scientific article published in August 2013

Functional human GRIN2B promoter polymorphism and variation of mental processing speed in older adults.

scientific article

High prevalence of multiple human herpesviruses in saliva from human immunodeficiency virus-infected persons in the era of highly active antiretroviral therapy

scientific article

Hippocampal Sclerosis of Aging Can Be Segmental: Two Cases and Review of the Literature

scientific article

Hippocampal sclerosis in advanced age: clinical and pathological features.

scientific article

Hippocampal sclerosis of aging, a prevalent and high-morbidity brain disease

scientific article

Hypodontia as a risk marker for epithelial ovarian cancer: a case-controlled study

scientific article

Impact of body mass index on treatment outcomes in endometrial cancer patients receiving doxorubicin and cisplatin: a Gynecologic Oncology Group study

scientific article

Improvement of bilateral motor functions in patients with Parkinson disease through the unilateral intraputaminal infusion of glial cell line-derived neurotrophic factor

scientific article (publication date: February 2005)

Inhibition of human microsomal PGE2 synthase-1 reduces seizure-induced increases of P-glycoprotein expression and activity at the blood-brain barrier

scientific article published on 22 October 2019

Interobserver variation in ovarian measurements using transvaginal sonography

scientific article published in October 1990

JC virus detection in bodily fluids: clues to transmission

scientific article published on 30 May 2006

Lab-on-a-chip methods for point-of-care measurements of salivary biomarkers of periodontitis

journal article published in 2007

Letter to the Editor: Authors' Response

scientific article published on 01 October 2009

Lifelong bilingualism maintains neural efficiency for cognitive control in aging

scientific article

Lipid peroxidation is an early event in the brain in amnestic mild cognitive impairment

scientific article published in November 2005

Long-term outcome of high-dose γ knife surgery in treatment of trigeminal neuralgia

scientific article published on 19 April 2013

Long-term survival of women with epithelial ovarian cancer detected by ultrasonographic screening

scientific article published in December 2011

Low prevalence of varicella zoster virus and herpes simplex virus type 2 in saliva from human immunodeficiency virus-infected persons in the era of highly active antiretroviral therapy

scientific article

Low sensitivity in clinical diagnoses of dementia with Lewy bodies

scientific article

Lymph node metastases and prognosis in patients with stage IA2 cervical cancer

scientific article published on 01 October 1996

Markov Transition Model to Dementia with Death as a Competing Event

scientific article

Markov chains and semi-Markov models in time-to-event analysis

scientific article

Matrix Metalloproteinase-Mediated Blood-Brain Barrier Dysfunction in Epilepsy.

scientific article

Memory-Related Frontal Brainwaves Predict Transition to Mild Cognitive Impairment in Healthy Older Individuals Five Years Before Diagnosis

scientific article published on 14 December 2020

Mild cognitive impairment: statistical models of transition using longitudinal clinical data

scientific article

Modeling the association between 43 different clinical and pathological variables and the severity of cognitive impairment in a large autopsy cohort of elderly persons

scientific article

Multi-state models and missing covariate data: Expectation-Maximization algorithm for likelihood estimation

scientific article published on 04 April 2017

Musical Training and Late-Life Cognition.

scientific article

Neuropathologic substrate of mild cognitive impairment.

scientific article published in January 2006

Neutron interstitial brachytherapy for malignant gliomas: a pilot study

scientific article

Oral fluids that detect cardiovascular disease biomarkers

scientific article published on August 2012

Outcome of reproductive age women with stage IA or IC invasive epithelial ovarian cancer treated with fertility-sparing therapy

scientific article published on 01 October 2002

Outcomes after diagnosis of mild cognitive impairment in a large autopsy series

scientific article published on 22 February 2017

Ovarian cancer screening in asymptomatic postmenopausal women by transvaginal sonography

scientific article

Ovarian cancer screening with annual transvaginal sonography: findings of 25,000 women screened

scientific article published in May 2007

Ovarian volume related to age.

scientific article published in June 2000

Patterns of salivary analytes provide diagnostic capacity for distinguishing chronic adult periodontitis from health

scientific article published on 29 August 2012

Peripheral (deep) but not periventricular MRI white matter hyperintensities are increased in clinical vascular dementia compared to Alzheimer's disease

scientific article

Phase II clinical trial using californium 252 fast neutron brachytherapy, external pelvic radiation, and extrafascial hysterectomy in the treatment of bulky, barrel-shaped stage IB cervical cancer

scientific article published in May 1986

Pittsburgh compound B and the postmortem diagnosis of Alzheimer disease.

scientific article

Post-acquisition processing confounds in brain volumetric quantification of white matter hyperintensities

scientific article published on 10 August 2019

Postoperative bleeding associated with antiplatelet and anticoagulant drugs: A retrospective study

scientific article published on 16 April 2019

Practice effects in a longitudinal, multi-center Alzheimer's disease prevention clinical trial.

scientific article published on 20 November 2012

Preclinical AD Workgroup staging: pathological correlates and potential challenges.

scientific article published on 19 April 2011

Predicting risk of malignancy in adnexal masses

scientific article published on 01 April 2010

Prediction of preclinical Alzheimer's disease: longitudinal rates of change in cognition

scientific article

Predictive value of specimen histology after preoperative radiotherapy in the treatment of bulky/barrel carcinoma of the cervix

scientific article published on 01 April 1992

Preoperative differentiation of malignant from benign ovarian tumors: the efficacy of morphology indexing and Doppler flow sonography

scientific article published on 01 October 2003

Preoperative radiation therapy followed by extrafascial hysterectomy in patients with stage II endometrial carcinoma

scientific article published on 01 September 1991

Prevalence and Clinical Phenotype of Quadruple Misfolded Proteins in Older Adults

scientific article published on 22 June 2020

Probability of fallopian tube and ovarian detection with transvaginal ultrasonography in normal women

scientific article published on 18 May 2016

Prognostic factors in early vulvar cancer

scientific article published on 01 September 1988

Prognostic implications of large volume residual disease in patients with advanced stage epithelial ovarian cancer

scientific article published on 01 June 1987

Quality of education and memory test performance in older men: the New York University Paragraph Recall Test normative data

scientific article

Rapid assessment of salivary MMP-8 and periodontal disease using lateral flow immunoassay

scientific article

Real-time polymerase chain reaction to determine the prevalence and copy number of epstein-barr virus and cytomegalovirus DNA in subgingival plaque at individual healthy and periodontal disease sites

scientific article published in July 2009

Reduced risk of incident AD with elective statin use in a clinical trial cohort

scientific article

Relating ovarian size to age, menopausal status, and use of hormones

scientific article published in February 2001

Relationship between herpesviruses and periodontal disease progression

scientific article published on 03 February 2020

Relative preservation of MMSE scores in autopsy-proven dementia with Lewy bodies

scientific article published on October 2009

Research on Parkinson disease

scholarly article by John T Slevin et al published 1 February 2005 in Journal of Neurosurgery

Rheumatoid arthritis and salivary biomarkers of periodontal disease

scientific article

Risk factors and global cognitive status related to brain arteriolosclerosis in elderly individuals

scientific article published on 6 January 2016

Risk of incident clinical diagnosis of Alzheimer's disease-type dementia attributable to pathology-confirmed vascular disease

scientific article published on 22 December 2016

Risk of malignancy in sonographically confirmed septated cystic ovarian tumors

scientific article

Risk of malignancy in unilocular ovarian cystic tumors less than 10 centimeters in diameter

scientific article published on 01 September 2003

Salivary and serum adiponectin and C-reactive protein levels in acute myocardial infarction related to body mass index and oral health

scientific article published on 23 August 2016

Salivary biomarkers associated with gingivitis and response to therapy

scientific article

Salivary biomarkers associated with myocardial necrosis: results from an alcohol septal ablation model

scientific article published on 28 September 2012

Salivary biomarkers of existing periodontal disease: a cross-sectional study

scientific article published on 01 March 2006

Salivary biomarkers of periodontal disease in response to treatment

scientific article

Salivary levels of Epstein-Barr virus DNA correlate with subgingival levels, not severity of periodontitis

scientific article published on 12 June 2009

Self-Reported Memory Complaints: A Comparison of Demented and Unimpaired Outcomes

scientific article published on March 2016

Self-Reported Sleep Apnea and Dementia Risk: Findings from the Prevention of Alzheimer's Disease with Vitamin E and Selenium Trial

scientific article published on November 2016

Self-reported head injury and risk of late-life impairment and AD pathology in an AD center cohort

scientific article

Self-reported memory complaints: implications from a longitudinal cohort with autopsies

scientific article

Serial ultrasonographic evaluation of ovarian abnormalities with a morphology index

scientific article published on 25 July 2014

Shared random effects analysis of multi-state Markov models: application to a longitudinal study of transitions to dementia.

scientific article published on February 2007

Specimen findings and survival after preoperative 252Cf neutron brachytherapy for stage II cervical carcinoma

scientific article

Spectral and complexity analysis of scalp EEG characteristics for mild cognitive impairment and early Alzheimer's disease.

scientific article

Stage I serous papillary carcinoma of the endometrium

scientific article published on 01 June 1989

Sugihara causality analysis of scalp EEG for detection of early Alzheimer's disease

scientific article

Survival Advantage Associated with Decrease in Stage at Detection from Stage IIIC to Stage IIIA Epithelial Ovarian Cancer

scientific article

Survival of Women With Type I and II Epithelial Ovarian Cancer Detected by Ultrasound Screening

scientific article published on 01 November 2018

Symptoms Relevant to Surveillance for Ovarian Cancer

scientific article published on 20 March 2017

Systemic metabolic effects of combined insulin-like growth factor-I and growth hormone therapy in patients who have sustained acute traumatic brain injury

scientific article published in December 2006

Tamoxifen-associated malignant endometrial tumors: pathologic features and expression of hormone receptors estrogen-alpha, estrogen-beta and progesterone; a case controlled study

scientific article published in February 2004

Tau is reduced in AD plasma and validation of employed ELISA methods

scientific article published on 15 May 2012

The Amygdala as a Locus of Pathologic Misfolding in Neurodegenerative Diseases

scientific article

The Effect of Vascular Neuropathology on Late-life Cognition: Results from the SMART Project

scientific article published on June 2016

The Statistical Modeling of Aging and Risk of Transition Project: Data Collection and Harmonization Across 11 Longitudinal Cohort Studies of Aging, Cognition, and Dementia

The accuracy of examination under anesthesia and transvaginal sonography in evaluating ovarian size

scientific article published on 9 August 2005

The efficacy of laser therapy in the treatment of cervical intraepithelial neoplasia

scientific article

The efficacy of transvaginal sonographic screening in asymptomatic women at risk for ovarian cancer

scientific article published in June 2000

The malignant potential of small cystic ovarian tumors in women over 50 years of age

scientific article published on 01 April 1998

The prognostic and therapeutic implications of cytologic atypia in patients with endometrial hyperplasia

scientific article published on 01 October 1994

The search for meaning-Symptoms and transvaginal sonography screening for ovarian cancer: predicting malignancy

scientific article published in August 2009

The treatment of lateral T1 and T2 squamous cell carcinomas of the vulva confined to the labium majus or minus

scientific article published on 5 October 2006

Therapeutic implications of lymph nodal spread in lateral T1 and T2 squamous cell carcinoma of the vulva

scientific article published on 01 October 1994

Tobacco Smoking and Dementia in a Kentucky Cohort: A Competing Risk Analysis

scientific article published on 01 January 2019

Transition from benign to malignant epithelium in mucinous and serous ovarian cystadenocarcinoma

scientific article published on October 1, 1992

Transitions to mild cognitive impairments, dementia, and death: findings from the Nun Study.

scientific article published on 12 April 2007

Transvaginal sonography as a screening method for the detection of early ovarian cancer

scientific article published on June 1997

Treatment of stage IIIB cervical cancer with Californium-252 fast-neutron brachytherapy and external photon therapy

scientific article published on 01 May 1987

Unilateral intraputamenal glial cell line-derived neurotrophic factor in patients with Parkinson disease: response to 1 year of treatment and 1 year of withdrawal

scientific article published on April 2007

Unilateral intraputaminal glial cell line-derived neurotrophic factor in patients with Parkinson disease: response to 1 year each of treatment and withdrawal

scholarly article by John T Slevin et al published 15 May 2006 in Neurosurgical Focus

University of Kentucky Sanders-Brown healthy brain aging volunteers: donor characteristics, procedures and neuropathology

scientific article

Utility of salivary biomarkers for demonstrating acute myocardial infarction.

scientific article

Visual Arts Education improves self-esteem for persons with dementia and reduces caregiver burden: A randomized controlled trial.

scientific article published in January 2018

Vitamin E and all-cause mortality: a meta-analysis

scientific article

White matter integrity is associated with cerebrospinal fluid markers of Alzheimer's disease in normal adults.

scientific article