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List of works by Mitsuaki Isobe

A DPP-4 inhibitor suppresses fibrosis and inflammation on experimental autoimmune myocarditis in mice

scientific article

A global in vivo Drosophila RNAi screen identifies NOT3 as a conserved regulator of heart function.

scientific article

ATF3 inhibits doxorubicin-induced apoptosis in cardiac myocytes: a novel cardioprotective role of ATF3.

scientific article

Anti-arrhythmic efficacy of nifekalant hydrochloride, a pure class III anti-arrhythmic agent, in patients with healed myocardial infarction and inducible sustained ventricular tachycardia

scientific article

Appropriateness rating for the application of optimal medical therapy and multidisciplinary care among heart failure patients

scientific article published on 17 November 2020

Atrial fibrillation type matters: greater infarct volume and worse neurological defects seen in acute cardiogenic cerebral embolism due to persistent or permanent rather than paroxysmal atrial fibrillation

scientific article published on 12 December 2017

Characteristics of cardiac allograft vasculopathy induced by immunomodulation in the miniature Swine

scientific article published on 18 April 2014

Comparative effects of carvedilol vs bisoprolol for severe congestive heart failure

scientific article

Coronary Artery Disease Severity and Cardiovascular Biomarkers in Patients with Peripheral Artery Disease

scientific article

Effect of High-dose Telmisartan on the Prevention of Recurrent Atrial Fibrillation in Hypertensive Patients

scientific article published on 22 October 2010

Effect of periodontitis on cardiovascular manifestations in Marfan syndrome. Critical common role of TGF-β

scientific article

Elimination of Ventricular Arrhythmia in Catecholaminergic Polymorphic Ventricular Tachycardia by Targeting "Catecholamine-Sensitive Area": A Dominant-Subordinate Relationship between Origin Sites of Bidirectional Ventricular Premature Contractions

scientific article published on 24 December 2016

Endocardial-only catheter ablation with substantial improvement in ventricular fibrillation recurrences in a patient with Brugada syndrome

scientific article published on 22 June 2016

Endothelial E-selectin potentiates neovascularization via endothelial progenitor cell-dependent and -independent mechanisms

scientific article

Factors and values at admission that predict a fulminant course of acute myocarditis: data from Tokyo CCU network database

scientific article

Gene therapy for heart transplantation-associated acute rejection, ischemia/reperfusion injury and coronary arteriosclerosis

scientific article published on June 2004

Genetic defects in a His-Purkinje system transcription factor, IRX3, cause lethal cardiac arrhythmias.

scientific article published on October 2015

Hemoptysis after five months of cryoballoon ablation: What is the relationship?

scientific article published on 31 May 2017

Hepatocyte growth factor: Effects on immune-mediated heart diseases

scientific article published on August 2006

High incidence of Aggregatibacter actinomycetemcomitans infection in patients with cerebral infarction and diabetic renal failure: a cross-sectional study

scientific article

High-fat diet increases vulnerability to atrial arrhythmia by conduction disturbance via miR-27b

scientific article published on December 2015

Impact of Alcohol Consumption on the Outcome of Catheter Ablation in Patients With Paroxysmal Atrial Fibrillation

scientific article

Impact of renal artery stent implantation on hypertension in patients with hemodialysis

scientific article

Integrating genetic, transcriptional, and functional analyses to identify 5 novel genes for atrial fibrillation

scientific article published on 14 August 2014

Left Atrial Appendage Thrombi Formation in Japanese Non-Valvular Atrial Fibrillation Patients During Anticoagulation Therapy - Warfarin vs. Direct Oral Anticoagulants

scientific article published on 7 February 2017

Modification of atrioventricular conduction in dogs by laser irradiation of Koch's triangle guided by balloon-tipped cardioscope

scientific article

Mst1 inhibits autophagy by promoting the interaction between Beclin1 and Bcl-2.

scientific article published on 20 October 2013

Muscle-specific RING finger 1 negatively regulates pathological cardiac hypertrophy through downregulation of calcineurin A.

scientific article

Novel C-terminus frameshift mutation, 1122fs/147, of HERG in LQT2: additional amino acids generated by frameshift cause accelerated inactivation

scientific article published in December 2004

Novel Dielectric Coagulometer Identifies Hypercoagulability in Patients with a High CHADS2 Score without Atrial Fibrillation

scientific article

Oxidative Stress Induced Ventricular Arrhythmia and Impairment of Cardiac Function in Nos1ap Deleted Mice

scientific article published on 09 May 2016

PPARα and PPARγ activators suppress the monocyte-macrophage apoB-48 receptor

scientific article published on April 16, 2003

Periodontitis in cardiovascular disease patients with or without Marfan syndrome--a possible role of Prevotella intermedia

scientific article

Pharmacological activation of the prostaglandin E2 receptor EP4 improves cardiac function after myocardial ischaemia/reperfusion injury

scientific article published on 18 September 2008

Pitavastatin suppresses acute and chronic rejection in murine cardiac allografts

scientific article

Popliteal Retrograde Approach is Effective and Safe for Superficial Femoral Artery Chronic Total Occlusion

scientific article

Preferential Pathway Pacing within the Aortic Sinus of Valsalva: Strong Evidence for the Existence of Preferential Conduction with Different Exit Sites Traversing the Ventricular Septum

scientific article published on 22 April 2015

Recent progress in research on molecular mechanisms of autophagy in the heart

scientific article

Regulation of autophagy by Beclin 1 in the heart

scientific journal article

Severe iatrogenic bradycardia related to the combined use of beta-blocking agents and sodium channel blockers

scientific article

Stretch of Atrial Myocytes Stimulates Recruitment of Macrophages via ATP Released Through Gap-Junction Channels

scientific article published on November 29, 2012

Surface Electrocardiogram Screening for Subcutaneous Implantable Cardioverter-Defibrillators in Japanese Patients With and Without Brugada Syndrome

scientific article published on 28 March 2017

T cell costimulation in the development of cardiac allograft vasculopathy: potential targets for therapeutic interventions

scientific article

Tea polyphenols regulate key mediators on inflammatory cardiovascular diseases

scientific article

The Efficacy of Isochronal 3D Mapping-Based Ablation of Ventricular Arrhythmia

scientific article published on 14 July 2017

The effectiveness of excimer laser coronary atherectomy with contrast medium for underexpanded stent: The findings of optical frequency domain imaging

scientific article published on 7 March 2015

The efficacy of excimer laser pretreatment for calcified nodule in acute coronary syndrome

scientific article

The impact of B-type natriuretic peptide levels on the suppression of accompanying atrial fibrillation in Wolff-Parkinson-White syndrome patients after accessory pathway ablation

scientific article published on 22 February 2016

Transvenous extraction of advisory implantable cardioverter defibrillator leads with a relatively long implant duration.

scientific article

Treatment of in-stent restenosis with excimer laser coronary angioplasty: benefits over scoring balloon angioplasty alone

scientific article

Two Susceptibility Loci to Takayasu Arteritis Reveal a Synergistic Role of the IL12B and HLA-B Regions in a Japanese Population

scientific article published on 03 July 2013

Vessel Wall Inflammation of Takayasu Arteritis Detected by Contrast-Enhanced Magnetic Resonance Imaging: Association with Disease Distribution and Activity

scientific article published on 31 December 2015