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List of works by Edwin Severin Iversen, Jr.

A Cross-Cancer Genetic Association Analysis of the DNA Repair and DNA Damage Signaling Pathways for Lung, Ovary, Prostate, Breast, and Colorectal Cancer

scientific article

A branching process model for flow cytometry and budding index measurements in cell synchrony experiments

scientific article published on January 1, 2009

A computational method to classify variants of uncertain significance using functional assay data with application to BRCA1

scientific article

A genome-wide association study identifies a new ovarian cancer susceptibility locus on 9p22.2.

scientific article

A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24.

scientific article published on 19 September 2010

A joint analysis of metabolomics and genetics of breast cancer

scientific article

A probabilistic model for cell cycle distributions in synchrony experiments

scientific article published on 12 February 2007

A prospective study of weight gain after premenopausal hysterectomy

scientific article

A systematic genetic assessment of 1,433 sequence variants of unknown clinical significance in the BRCA1 and BRCA2 breast cancer-predisposition genes

scientific article

A targeted genetic association study of epithelial ovarian cancer susceptibility

scientific article published on February 2016

ABO blood group and risk of epithelial ovarian cancer within the Ovarian Cancer Association Consortium

scientific article

Assessment of the Clinical Relevance of BRCA2 Missense Variants by Functional and Computational Approaches

scientific article published on 17 January 2018

Assessment of variation in immunosuppressive pathway genes reveals TGFBR2 to be associated with risk of clear cell ovarian cancer

scientific article published on 21 June 2016

Association between DNA damage response and repair genes and risk of invasive serous ovarian cancer

scientific article

Association between Prepregnancy Body Mass Index and Gestational Weight Gain with Size, Tempo, and Velocity of Infant Growth: Analysis of the Newborn Epigenetic Study Cohort

scientific article published on 02 May 2016

Association between invasive ovarian cancer susceptibility and 11 best candidate SNPs from breast cancer genome-wide association study

scientific article published on 20 March 2009

Association of single nucleotide polymorphisms in glycosylation genes with risk of epithelial ovarian cancer

scientific article published in February 2008

BAYESIAN MODEL SEARCH AND MULTILEVEL INFERENCE FOR SNP ASSOCIATION STUDIES

scientific article

BRCAPRO validation, sensitivity of genetic testing of BRCA1/BRCA2, and prevalence of other breast cancer susceptibility genes

article

Bridging the gaps: using an NHP model to predict single dose radiation absorption in humans

scientific article published on 29 October 2018

Characterization of BRCA1 and BRCA2 mutations in a large United States sample

scientific article

Characterization of dependencies between growth and division in budding yeast.

scientific article published in February 2017

Charting the landscape of tandem BRCT domain-mediated protein interactions

scientific article

Cis-eQTL analysis and functional validation of candidate susceptibility genes for high-grade serous ovarian cancer

scientific article published on 22 September 2015

Classification of Missense Mutations of Disease Genes

scientific article

Clonal Analysis of the Neonatal Mouse Heart using Nearest Neighbor Modeling

scientific article published on 22 August 2020

Cohort profile for the Nurture Observational Study examining associations of multiple caregivers on infant growth in the Southeastern USA.

scientific article published on 08 February 2017

Combined and interactive effects of environmental and GWAS-identified risk factors in ovarian cancer

scientific article published on 05 March 2013

Common Genetic Variation In Cellular Transport Genes and Epithelial Ovarian Cancer (EOC) Risk

scientific article published on 19 June 2015

Common Genetic Variation in Circadian Rhythm Genes and Risk of Epithelial Ovarian Cancer (EOC).

scientific article

Common alleles in candidate susceptibility genes associated with risk and development of epithelial ovarian cancer

scientific article

Common variants at 19p13 are associated with susceptibility to ovarian cancer

scientific article

Common variants at the CHEK2 gene locus and risk of epithelial ovarian cancer

scientific article

Comprehensive annotation of BRCA1 and BRCA2 missense variants by functionally validated sequence-based computational prediction models

scientific article published on 08 June 2018

Consortium analysis of gene and gene-folate interactions in purine and pyrimidine metabolism pathways with ovarian carcinoma risk

scientific article

Construction and analysis of the NCI-EDRN breast cancer reference set for circulating markers of disease

scientific article

DNA Methylation of Regulatory Regions of Imprinted Genes at Birth and Its Relation to Infant Temperament

scientific article

Depression in pregnancy, infant birth weight and DNA methylation of imprint regulatory elements

scientific article published on July 1, 2012

Early Child Care and Weight Status in a Cohort of Predominantly Black Infants in the Southeastern United States

scientific article published on 16 October 2019

Effect of Hysterectomy With Ovarian Preservation on Ovarian Function

scientific article published on December 1, 2011

Epigenetic analysis leads to identification of HNF1B as a subtype-specific susceptibility gene for ovarian cancer

scientific article published in 2013

Epigenetic suppression of the TGF-beta pathway revealed by transcriptome profiling in ovarian cancer.

scientific article

Epithelial-Mesenchymal Transition (EMT) Gene Variants and Epithelial Ovarian Cancer (EOC) Risk

scientific article

Erratum: Corrigendum: Common variants at 19p13 are associated with susceptibility to ovarian cancer

scholarly article published in Nature Genetics

Erythrocyte folate concentrations, CpG methylation at genomically imprinted domains, and birth weight in a multiethnic newborn cohort

scientific article

European American stratification in ovarian cancer case control data: the utility of genome-wide data for inferring ancestry

scientific article

Evaluating the ovarian cancer gonadotropin hypothesis: a candidate gene study

scientific article published on 17 December 2014

Evaluation of candidate stromal epithelial cross-talk genes identifies association between risk of serous ovarian cancer and TERT, a cancer susceptibility "hot-spot"

scientific article

Evaluation of established breast cancer risk factors as modifiers of BRCA1 or BRCA2: a multi-center case-only analysis

scientific article

Exome genotyping arrays to identify rare and low frequency variants associated with epithelial ovarian cancer risk

scientific article published on 4 July 2016

Expression signatures of TP53 mutations in serous ovarian cancers

scientific article

Functional annotation signatures of disease susceptibility loci improve SNP association analysis

scientific article

Functional assays provide a robust tool for the clinical annotation of genetic variants of uncertain significance.

scientific article published on 02 March 2016

GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer

scientific article published on April 2013

Gender-specific methylation differences in relation to prenatal exposure to cigarette smoke

scientific article published on December 20, 2011

Gene expression phenotypes of atherosclerosis

scientific article published on 05 August 2004

Gene expression predictors of breast cancer outcomes

scientific article published on May 10, 2003

Gene expression profiling and genetic markers in glioblastoma survival.

scientific article published in May 2005

Genetic evidence and integration of various data sources for classifying uncertain variants into a single model

scientific article

Genetic variation in insulin-like growth factor 2 may play a role in ovarian cancer risk

scientific article

Genome-wide Analysis Identifies Novel Loci Associated with Ovarian Cancer Outcomes: Findings from the Ovarian Cancer Association Consortium

scientific article

Genome-wide Analysis of Common Copy Number Variation and Epithelial Ovarian Cancer Risk

scientific article published on 04 April 2019

Genome-wide association study of subtype-specific epithelial ovarian cancer risk alleles using pooled DNA.

scientific article published on 5 November 2013

Germline copy number variation and ovarian cancer survival

scientific article

Global control of cell-cycle transcription by coupled CDK and network oscillators

scientific article

Hormonal risk factors for ovarian cancer in premenopausal and postmenopausal women

scientific article published on 25 February 2008

Identification and molecular characterization of a new ovarian cancer susceptibility locus at 17q21.31.

scientific article published on January 2013

Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer

scientific article

Identification of six new susceptibility loci for invasive epithelial ovarian cancer

scientific article published on 12 January 2015

Impact of amino acid substitutions at secondary structures in the BRCT domains of the tumor suppressor BRCA1: Implications for clinical annotation

scientific article published on 14 February 2019

Inherited variants in mitochondrial biogenesis genes may influence epithelial ovarian cancer risk

scientific article

Integrated modeling of clinical and gene expression information for personalized prediction of disease outcomes

scholarly article

Integration of functional assay data results provides strong evidence for classification of hundreds of BRCA1 variants of uncertain significance

scientific article published on 22 October 2020

Investigation of Exomic Variants Associated with Overall Survival in Ovarian Cancer

scientific article

LIN28B polymorphisms influence susceptibility to epithelial ovarian cancer

scientific article published on 11 April 2011

Limited family structure and breast cancer risk

scientific article published on 01 November 2007

Mapping nucleosome positions using DNase-seq

scientific article published on 15 January 2016

Maternal stress, preterm birth, and DNA methylation at imprint regulatory sequences in humans

scientific article

Methylation variation at IGF2 differentially methylated regions and maternal folic acid use before and during pregnancy

scientific article

MicroRNA processing and binding site polymorphisms are not replicated in the Ovarian Cancer Association Consortium

scientific article published on 2 June 2011

Microarray analysis of early stage serous ovarian cancers shows profiles predictive of favorable outcome

scientific article

Molecular Signatures of Epithelial Ovarian Cancer: Analysis of Associations with Tumor Characteristics and Epidemiologic Risk Factors

scientific article published on 05 August 2013

Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer

scientific article published on April 2013

Network-Based Integration of GWAS and Gene Expression Identifies a HOX-Centric Network Associated with Serous Ovarian Cancer Risk

scientific article

Ovarian cancer risk associated with inherited inflammation-related variants

scientific article published on 26 January 2012

PALB2, CHEK2 and ATM rare variants and cancer risk: data from COGS

scientific article published in December 2016

Patterns of gene expression that characterize long-term survival in advanced stage serous ovarian cancers.

scientific article

Polymorphism in the GALNT1 gene and epithelial ovarian cancer in non-Hispanic white women: the Ovarian Cancer Association Consortium

scientific article

Polymorphism in the IL18 gene and epithelial ovarian cancer in non-Hispanic white women

scientific article

Polymorphisms in stromal genes and susceptibility to serous epithelial ovarian cancer: a report from the Ovarian Cancer Association Consortium

scientific article published on 27 May 2011

Population-Calibrated Gene Characterization: Estimating Age at Onset Distributions Associated With Cancer Genes

scientific article

Prediction of optimal versus suboptimal cytoreduction of advanced-stage serous ovarian cancer with the use of microarrays

scientific article published on 01 April 2004

Probing structure-function relationships in missense variants in the carboxy-terminal region of BRCA1

scientific article (publication date: 2014)

Regular Multivitamin Supplement Use, Single Nucleotide Polymorphisms in ATIC, SHMT2, and SLC46A1, and Risk of Ovarian Carcinoma

scientific article published on 19 March 2012

Risk Prediction for Epithelial Ovarian Cancer in 11 United States-Based Case-Control Studies: Incorporation of Epidemiologic Risk Factors and 17 Confirmed Genetic Loci

scientific article

Risk of ovarian cancer and inherited variants in relapse-associated genes

scientific article

Single nucleotide polymorphisms in the TP53 region and susceptibility to invasive epithelial ovarian cancer

scientific article published on 10 March 2009

Tagging single nucleotide polymorphisms in cell cycle control genes and susceptibility to invasive epithelial ovarian cancer

scientific article published in April 2007

The Risk of Ovarian Cancer Increases with an Increase in the Lifetime Number of Ovulatory Cycles: An Analysis from the Ovarian Cancer Cohort Consortium (OC3)

scientific article published on 13 January 2020

The role of KRAS rs61764370 in invasive epithelial ovarian cancer: implications for clinical testing

scientific article published on 8 March 2011

Trinucleotide repeat polymorphisms in the androgen receptor gene and risk of ovarian cancer.

scientific article published in March 2007

Validation of ovarian cancer gene expression signatures for survival and subtype in formalin fixed paraffin embedded tissues

scientific article published on December 26, 2012

Validity of models for predicting BRCA1 and BRCA2 mutations

scientific article published on October 2007

Variants in genes encoding small GTPases and association with epithelial ovarian cancer susceptibility

scientific article published in PLoS ONE

Variation at 8q24 and 9p24 and risk of epithelial ovarian cancer

scientific article

Vitamin D receptor (VDR) polymorphisms and risk of ovarian cancer in Caucasian and African American women

scientific article published on December 21, 2012

rs495139 in the TYMS-ENOSF1 Region and Risk of Ovarian Carcinoma of Mucinous Histology

scientific article published on 21 August 2018