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List of works by Karin C Nitiss

A conserved SUMO pathway repairs topoisomerase DNA-protein cross-links by engaging ubiquitin-mediated proteasomal degradation

scientific article published on 13 November 2020

A dual mechanism of action of the anticancer agent F 11782 on human topoisomerase II alpha

scientific article published in August 2003

A mutation in human topoisomerase II alpha whose expression is lethal in DNA repair-deficient yeast cells

scientific article published on 22 March 2004

Aberrant topoisomerase-1 DNA lesions are pathogenic in neurodegenerative genome instability syndromes

scientific article

DNA Damage by an essential enzyme: A delicate balance act on the tightrope

scientific article published on 09 July 2019

Detection of Topoisomerase Covalent Complexes in Eukaryotic Cells

scientific article published in January 2018

End-processing during non-homologous end-joining: a role for exonuclease 1

scientific article

Enhancing drug accumulation in Saccharomyces cerevisiae by repression of pleiotropic drug resistance genes with chimeric transcription repressors

scientific article published on 09 May 2008

Gimatecan (sigma-tau industrie farmaceutiche riunite/novartis).

scientific article

Mutation of a conserved active site residue converts tyrosyl-DNA phosphodiesterase I into a DNA topoisomerase I-dependent poison

scientific article

Proteolytic Degradation of Topoisomerase II (Top2) Enables the Processing of Top2⋅DNA and Top2⋅RNA Covalent Complexes by Tyrosyl-DNA-Phosphodiesterase 2 (TDP2)

scientific article

Roles of nonhomologous end-joining pathways in surviving topoisomerase II-mediated DNA damage

scientific article published on 01 June 2006

TDP1 is required for efficient non-homologous end joining in human cells.

scientific article

TDP1 promotes assembly of non-homologous end joining protein complexes on DNA.

scientific article published on 17 March 2015

Tdp2: A Means to Fixing the Ends

scientific article published on March 7, 2013

The western-type diet induces anti-HMGB1 autoimmunity in Apoe(-/-) mice.

scientific article published on 19 May 2016

Trapped topoisomerase II initiates formation of de novo duplications via the nonhomologous end-joining pathway in yeast

scientific article published on 12 October 2020

Twisting and ironing: doxorubicin cardiotoxicity by mitochondrial DNA damage

scientific article

Tyrosyl-DNA phosphodiesterase (Tdp1) participates in the repair of Top2-mediated DNA damage

scientific article

UnTTrapping the ends: a new player in overcoming protein linked DNA damage

scientific article published on 01 February 2010

Yeast Tdp1 regulates the fidelity of nonhomologous end joining

scientific article

Yeast recombination pathways triggered by topoisomerase II-mediated DNA breaks

scientific article