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List of works by Martin J. Lohse

2',3'-Dideoxy-N6-cyclohexyladenosine: an adenosine derivative with antagonist properties at adenosine receptors.

scientific article published on October 1988

2-Alkynyl derivatives of adenosine and adenosine-5'-N-ethyluronamide as selective agonists at A2 adenosine receptors ⬇️

scientific article published on June 26, 1992

2-Chloro-N6-[3H]cyclopentyladenosine ([3H]CCPA)--a high affinity agonist radioligand for A1 adenosine receptors

scientific article

2-Chloro-N6-cyclopentyladenosine: a highly selective agonist at A1 adenosine receptors

scientific article

A FlAsH-based FRET approach to determine G protein-coupled receptor activation in living cells

scientific article published on 17 February 2005

A dileucine motif in the C terminus of the β 2 -adrenergic receptor is involved in receptor internalization ⬇️

scientific article published on November 11, 1997

A fluorescence resonance energy transfer-based M2 muscarinic receptor sensor reveals rapid kinetics of allosteric modulation

scientific article published on 18 January 2010

A functional genetic variation of SLC6A2 repressor hsa-miR-579-3p upregulates sympathetic noradrenergic processes of fear and anxiety

scientific article published on 19 October 2018

A new type of ERK1/2 autophosphorylation causes cardiac hypertrophy

scientific article

A novel fluorescence method for the rapid detection of functional beta1-adrenergic receptor autoantibodies in heart failure

scientific article published on 13 July 2007

A role for caspase-1 in heart failure

scientific article published on 15 February 2007

A small region in phosducin inhibits G-protein betagamma-subunit function.

scientific article published on August 1997

A technique for monitoring multiple signals with a combination of prism-based total internal reflection fluorescence microscopy and epifluorescence microscopy

scientific article published on 13 August 2009

A universal bioluminescence resonance energy transfer sensor design enables high-sensitivity screening of GPCR activation dynamics

scientific article published on 07 August 2018

Activating beta-1-adrenoceptor antibodies are not associated with cardiomyopathies secondary to valvular or hypertensive heart disease

scientific article published on 01 November 1999

Activation and deactivation kinetics of alpha 2A- and alpha 2C-adrenergic receptor-activated G protein-activated inwardly rectifying K+ channel currents

scientific article

Activation of AP-1 contributes to the beta-adrenoceptor-mediated myocardial induction of interleukin-6.

scientific article

Activation of beta-adrenergic receptor kinase during myocardial ischemia

scientific article published on 01 September 1996

Activation of the A3 adenosine receptor affects cell cycle progression and cell growth

scientific article

Activation of α2B-Adrenoceptors Mediates the Cardiovascular Effects of Etomidate ⬇️

scientific article published on October 1, 2003

Acute changes of myocardial creatine kinase gene expression under beta-adrenergic stimulation

scientific article published on 01 November 2000

Adenosine A1 receptor gene structure and regulation in normotensive and spontaneously hypertensive rats

scientific article published on 01 August 1992

Adenosine receptor agonists: synthesis and biological evaluation of 1-deaza analogues of adenosine derivatives

scientific article published on June 1988

Adenosine receptors on heart muscle

scientific article published on 01 August 1984

Administration of the cyclic peptide COR-1 in humans (phase I study): ex vivo measurements of anti-β1-adrenergic receptor antibody neutralization and of immune parameters

scientific article published on 11 September 2012

Advanced fluorescence microscopy reveals disruption of dynamic CXCR4 dimerization by subpocket-specific inverse agonists

scientific article published on 04 November 2020

Affinities of barbiturates for the GABA-receptor complex and A1 adenosine receptors: a possible explanation of their excitatory effects

scientific article published in August 1987

Agonist photoaffinity labeling of A1 adenosine receptors: persistent activation reveals spare receptors.

scientific article

Agonist regulation of human beta2-adrenergic receptor mRNA stability occurs via a specific AU-rich element

scientific article

Agonist-selective, receptor-specific interaction of human P2Y receptors with beta-arrestin-1 and -2

scientific article

All-optical microscope autofocus based on an electrically tunable lens and a totally internally reflected IR laser.

scientific article published in February 2018

Alpha-1 adrenoceptor-mediated positive inotropic effect and inositol trisphosphate increase in mammalian heart

scientific article published on 01 April 1988

Alterations in the myocardial creatine kinase system precede the development of contractile dysfunction in beta(1)-adrenergic receptor transgenic mice

scientific article published in April 2003

Alterations of phospholamban function can exhibit cardiotoxic effects independent of excessive sarcoplasmic reticulum Ca2+-ATPase inhibition

scientific article

Altered calcium handling is critically involved in the cardiotoxic effects of chronic beta-adrenergic stimulation

scientific article published on 16 February 2004

Altered expression of beta-adrenergic receptor kinase and beta 1-adrenergic receptors in the failing human heart.

scientific article

An RNA molecule that specifically inhibits G-protein-coupled receptor kinase 2 in vitro

scientific article published on 29 January 2008

Analysis of beta-adrenergic receptor mRNA levels in human ventricular biopsy specimens by quantitative polymerase chain reactions: progressive reduction of beta 1-adrenergic receptor mRNA in heart failure

scientific article published on 01 January 1996

Analysis of receptor oligomerization by FRAP microscopy.

scientific article

Antibodies to cardiac receptors

scientific article published on 01 December 2012

Arrestin interactions with G protein-coupled receptors.

scientific article

Autoantibodies activating human beta1-adrenergic receptors are associated with reduced cardiac function in chronic heart failure.

scientific article

Autoradiographic visualization of A1 adenosine receptors in rat brain with [3H]8-cyclopentyl-1,3-dipropylxanthine

scientific article published in April 1990

Autoradiographic visualization of A1-adenosine receptors in brain and peripheral tissues of rat and guinea pig using 125I-HPIA.

scientific article published on May 1988

Barbiturates are selective antagonists at A1 adenosine receptors

scientific article published on December 1985

Beta 1-adrenergic receptor-directed autoimmunity as a cause of dilated cardiomyopathy in rats.

scientific article published on 26 July 2006

Beta-adrenoceptor polymorphisms and heart failure.

scientific article published on February 2004

Beta-arrestin binding to the beta2-adrenergic receptor requires both receptor phosphorylation and receptor activation.

scientific article

Beta2-adrenergic receptor redistribution in heart failure changes cAMP compartmentation.

scientific article published on 25 February 2010

Binding of Gbetagamma subunits to cRaf1 downregulates G-protein-coupled receptor signalling

scientific article published on September 1999

Bioluminescence resonance energy transfer-based biosensors allow monitoring of ligand- and transducer-mediated GPCR conformational changes

scientific article published on 07 August 2018

Blocking them all: beta-arrestins inhibit cellular signaling

scientific article published on 01 September 2008

Building a new conceptual framework for receptor heteromers

scientific article

Calcium channel function and regulation in beta 1- and beta 2-adrenoceptor transgenic mice

scientific article published on 9 April 2004

Calcium-antagonist receptors in cardiomyopathy

scientific article

Cardiac RKIP induces a beneficial β-adrenoceptor-dependent positive inotropy.

scientific article published on 19 October 2015

Cardiac hypertrophy: targeting Raf/MEK/ERK1/2-signaling.

scientific article published on 08 August 2009

Cardiac myosin missense mutations cause dilated cardiomyopathy in mouse models and depress molecular motor function.

scientific article

Cell type-specific regulation of beta2-adrenoceptor mRNA by agonists

scientific article published on July 1997

Changes of Creatine Kinase Gene Expression in Rat Heart Post-Myocardial Infarction ⬇️

scientific article published on April 1, 1998

Characterization of [3H]phenobarbital binding to rat brain membranes

scientific article published in November 1984

Characterization of the solubilized A1 adenosine receptor from rat brain membranes

scientific article published on May 1986

Chemical modification of A1 adenosine receptors in rat brain membranes. Evidence for histidine in different domains of the ligand binding site

scientific article published on November 1988

Common genomic response in different mouse models of beta-adrenergic-induced cardiomyopathy

scientific article published on 17 November 2003

Comparative pharmacology of human adenosine receptor subtypes - characterization of stably transfected receptors in CHO cells.

scientific article published on January 1998

Comparative pharmacology of human beta-adrenergic receptor subtypes--characterization of stably transfected receptors in CHO cells

scientific article

Comparative rates of desensitization of beta-adrenergic receptors by the beta-adrenergic receptor kinase and the cyclic AMP-dependent protein kinase ⬇️

scientific article published on July 15, 1991

Comparison of the activation kinetics of the M3 acetylcholine receptor and a constitutively active mutant receptor in living cells

scientific article published on 07 May 2012

Conformational cross-talk between alpha2A-adrenergic and mu-opioid receptors controls cell signaling

scientific article published on 13 January 2008

Constitutive activation of PKA catalytic subunit in adrenal Cushing's syndrome

scientific article published on 26 February 2014

Constitutive activity of the human beta(1)-adrenergic receptor in beta(1)-receptor transgenic mice.

scientific article

Constitutively active germline mutation of the thyrotropin receptor gene as a cause of congenital hyperthyroidism

scientific article published on 01 December 1997

Context-Dependent Signaling of CXC Chemokine Receptor 4 and Atypical Chemokine Receptor 3

scientific article published on 15 May 2019

Critical role of transcription factor cyclic AMP response element modulator in beta1-adrenoceptor-mediated cardiac dysfunction.

scientific article

Crosstalk between Galpha(i)- and Galpha(q)-coupled receptors is mediated by Gbetagamma exchange.

scientific article published on September 1999

Crosstalk between sentinel and helper macrophages permits neutrophil migration into infected uroepithelium

scientific article

Cyclic AMP Imaging in Adult Cardiac Myocytes Reveals Far-Reaching β 1 -Adrenergic but Locally Confined β 2 -Adrenergic Receptor–Mediated Signaling

scientific article published on 12 October 2006

Cyclopeptide COR-1 to treat beta1-adrenergic receptor antibody-induced heart failure

scientific article published in PLoS ONE

Demonstration of Ri-type adenosine receptors in bovine myocardium by radioligand binding

scientific article published on January 1985

Desensitization of the isolated beta 2-adrenergic receptor by beta-adrenergic receptor kinase, cAMP-dependent protein kinase, and protein kinase C occurs via distinct molecular mechanisms

scientific article (publication date: 31 March 1992)

Detection of anti-β1-AR autoantibodies in heart failure by a cell-based competition ELISA

scientific article published on 18 July 2012

Determination of onset of sexual maturation and mating behavior by melanocortin receptor 4 polymorphisms

scientific article

Developing chemical genetic approaches to explore G protein-coupled receptor function: validation of the use of a receptor activated solely by synthetic ligand (RASSL).

scientific article published on 31 August 2011

Differential conformational requirements for activation of G proteins and the regulatory proteins arrestin and G protein-coupled receptor kinase in the G protein-coupled receptor for parathyroid hormone (PTH)/PTH-related protein

scientific article

Differential control of adrenal and sympathetic catecholamine release by alpha 2-adrenoceptor subtypes

scientific article published on 22 May 2003

Differential signaling of the endogenous agonists at the beta2-adrenergic receptor

scientific article published on 13 September 2010

Dimerization in GPCR mobility and signaling

scientific article

Direct evidence for a beta 1-adrenergic receptor-directed autoimmune attack as a cause of idiopathic dilated cardiomyopathy

scientific article

Direct inhibition of cardiac hyperpolarization-activated cyclic nucleotide-gated pacemaker channels by clonidine

scientific article published on 29 January 2007

Direct optical recording of intrinsic efficacy at a G protein-coupled receptor

scientific article published on December 2003

Disruption of cardiac Ena-VASP protein localization in intercalated disks causes dilated cardiomyopathy

scientific article published on 21 August 2003

Distinct pharmacological properties of morphine metabolites at G(i)-protein and β-arrestin signaling pathways activated by the human μ-opioid receptor

scientific article published on 17 March 2011

Distinct pools of cAMP centre on different isoforms of adenylyl cyclase in pituitary-derived GH3B6 cells.

scientific article

Dobutamine-stress magnetic resonance microimaging in mice : acute changes of cardiac geometry and function in normal and failing murine hearts

scientific article published in March 2001

Dual actions of adenosine on rat peritoneal mast cells

scientific article published on 01 May 1987

Dual regulation of the parathyroid hormone (PTH)/PTH-related peptide receptor signaling by protein kinase C and beta-arrestins.

scientific article published in October 2002

Dynamics of receptor/G protein coupling in living cells

scientific article published on 17 November 2005

Early impairment of calcium handling and altered expression of junctin in hearts of mice overexpressing the beta1-adrenergic receptor

scientific article

Effects of 1,3-dipropyl-8-cyclopentylxanthine (DPCPX), a highly selective adenosine receptor antagonist, on force of contraction in guinea-pig atrial and ventricular cardiac preparations

scientific article published on 01 August 1989

Effects of adenosine on histamine release from human lung fragments

scientific article published on January 1, 1992

Effects of phosducin on the GTPase cycle of Go.

scientific article published on April 1998

Effects of temperature and membrane phase transitions on ligand binding to alpha 2-receptors of human platelets

scientific article

Effects of two Gbetagamma-binding proteins--N-terminally truncated phosducin and beta-adrenergic receptor kinase C terminus (betaARKct)--in heart failure

scientific article published in August 2003

Erratum: Cardiac RKIP induces a beneficial β-adrenoceptor-dependent positive inotropy

scientific article published in February 2016

Evolutionary action and structural basis of the allosteric switch controlling β2AR functional selectivity.

scientific article published on 18 December 2017

Exploring the Biology of G Protein-Coupled Receptors from In Vitro to In Vivo

scientific article

Expression of beta 2-adrenoceptors in halobacteria

scientific article published in February 1997

Expression of beta-arrestins and beta-adrenergic receptor kinases in the failing human heart

scientific article published on 01 February 1994

Expression of phosducin in a phosducin-negative cell line reveals functions of a Gbetagamma-binding protein

scientific article published on September 1996

Expression, purification, and characterization of the cGMP-dependent protein kinases I beta and II using the baculovirus system

scientific journal article

FRET measurements of intracellular cAMP concentrations and cAMP analog permeability in intact cells

scientific article

FRET-based sensors for the human M1-, M3-, and M5-acetylcholine receptors

scientific article published on 30 July 2010

Feedback inhibition of catecholamine release by two different alpha2-adrenoceptor subtypes prevents progression of heart failure

scientific article published in November 2002

Fluorescence resonance energy transfer analysis of alpha 2a-adrenergic receptor activation reveals distinct agonist-specific conformational changes.

scientific article

Fluorescence resonance energy transfer-based analysis of cAMP dynamics in live neonatal rat cardiac myocytes reveals distinct functions of compartmentalized phosphodiesterases

scientific article published on 3 June 2004

Fluorescence/bioluminescence resonance energy transfer techniques to study G-protein-coupled receptor activation and signaling

scientific article

Fluorescent labeling of tetracysteine-tagged proteins in intact cells

scientific article

Fluorescent sensors for rapid monitoring of intracellular cGMP

scientific article published on 01 January 2006

Formation of a ternary complex among NHERF1, beta-arrestin, and parathyroid hormone receptor.

scientific article

G Protein activation without subunit dissociation depends on a G{alpha}(i)-specific region

scientific article published on 2 May 2005

G protein-coupled receptor oligomerization revisited: functional and pharmacological perspectives

scientific article published on 10 February 2014

G protein-coupled receptors: too many dimers?

scientific article published on 01 December 2006

G-Proteins and their regulators

scientific article published on 01 July 1999

G-protein-coupled receptor kinases

scientific article published on 01 April 1996

G-protein-coupled receptor kinases and the heart.

scientific article

GPCR and G proteins: drug efficacy and activation in live cells.

scientific article

GPCR-OKB: the G Protein Coupled Receptor Oligomer Knowledge Base.

scientific article

Gene amplification and functional diversification of melanocortin 4 receptor at an extremely polymorphic locus controlling sexual maturation in the platyfish

scientific article published on 27 September 2013

Gi protein activation in intact cells involves subunit rearrangement rather than dissociation

scientific article

Gq-mediated Ca2+ signals inhibit adenylyl cyclases 5/6 in vascular smooth muscle cells

scientific article published on 4 November 2009

Gs activation is time-limiting in initiating receptor-mediated signaling.

scientific article published on 8 September 2006

High-resolution spatiotemporal analysis of receptor dynamics by single-molecule fluorescence microscopy.

scientific article published on 25 July 2014

Hypoglycemia-dependent beta2-adrenoceptor downregulation: a contributing factor to hypoglycemia unawareness in patients with Type-1 diabetes?

scientific article

Identification of a C-terminal binding site for G-protein betagamma-subunits in phosducin-like protein.

scientific article

Identification of the ligand-binding subunit of the human 5-hydroxytryptamine1A receptor with N-(p-azido-m-[125I] iodophenethyl)spiperone, a high affinity radioiodinated photoaffinity probe

scientific article

Imaging cytoplasmic cAMP in mouse brainstem neurons

scientific article

Immunofluorescent imaging of beta 1- and beta 2-adrenergic receptors in rat kidney.

scientific article

Increased fear learning, spatial learning as well as neophobia in Rgs2-/- mice.

scientific article published on 28 August 2017

Inhibition of G-protein betagamma-subunit functions by phosducin-like protein.

scientific article published on March 1996

Inhibition of Na(+)-H(+) exchange prevents hypertrophy, fibrosis, and heart failure in beta(1)-adrenergic receptor transgenic mice

scientific article published on 01 April 2002

Integrin alpha E(CD103)beta 7 influences cellular shape and motility in a ligand-dependent fashion

scientific article

Interaction between the release of adenosine and noradrenaline during sympathetic stimulation: a feed-back mechanism in rat heart

scientific article

Interaction of barbiturates with adenosine receptors in rat brain

scientific article published on May 1984

Interactions between intracellular cyclic AMP and agonist-induced inositol phospholipid breakdown in isolated gastric mucosal cells of the rat.

scientific article

Interactions of phosducin with defined G protein beta gamma-subunits

scientific article published on May 1996

Interactions of phosducin with the subunits of G-proteins. Binding to the alpha as well as the betagamma subunits

scientific article published on 01 April 1998

Interference with ERK Thr188 phosphorylation impairs pathological but not physiological cardiac hypertrophy ⬇️

scientific article published on April 15, 2013

Internalization determinants of the parathyroid hormone receptor differentially regulate beta-arrestin/receptor association

scientific article

Internalized TSH receptors en route to the TGN induce local Gs-protein signaling and gene transcription

scientific article

International Union of Basic and Clinical Pharmacology. LXVII. Recommendations for the recognition and nomenclature of G protein-coupled receptor heteromultimers.

scientific article published on March 2007

International Workshop at the Nobel Forum, Karolinska Institutet on G protein-coupled receptors: finding the words to describe monomers, oligomers, and their molecular mechanisms and defining their meaning. Can a consensus be reached?

scientific article published in October 2010

Interstitial remodeling in beta1-adrenergic receptor transgenic mice

scientific article published on 24 November 2006

Kinetic analysis of G protein-coupled receptor signaling using fluorescence resonance energy transfer in living cells

scientific article published on January 2007

Kinetics and mechanism of G protein-coupled receptor activation.

scientific article published on 17 December 2013

Kinetics of G-protein-coupled receptor signalling and desensitization

scientific article published on 01 December 2004

Labelling of Ri adenosine receptors in rat fat cell membranes with (-)-[125iodo]N6-hydroxyphenylisopropyladenosine

scientific article published on June 1984

Ligand Binding Ensembles Determine Graded Agonist Efficacies at a G Protein-coupled Receptor

scientific article published on 13 June 2016

Ligand-Specific Restriction of Extracellular Conformational Dynamics Constrains Signaling of the M2 Muscarinic Receptor.

scientific article published on 06 June 2017

Ligand-induced phosphorylation/dephosphorylation of the endogenous bradykinin B2 receptor from human fibroblasts

scientific article published on December 1996

Live cell monitoring of mu-opioid receptor-mediated G-protein activation reveals strong biological activity of close morphine biosynthetic precursors

scientific article

Measurement of the millisecond activation switch of G protein-coupled receptors in living cells

scientific article

Mechanism of A2 adenosine receptor activation. I. Blockade of A2 adenosine receptors by photoaffinity labeling

scientific article published on 01 April 1991

Mechanism of activation of A2 adenosine receptors. II. A restricted collision-coupling model of receptor-effector interaction

scientific article published on 01 April 1991

Mechanisms involved in adrenergic receptor desensitization.

scientific article published on August 1990

MicroRNA hsa-miR-4717-5p regulates RGS2 and may be a risk factor for anxiety-related traits

scientific article published on 2 April 2015

Microscopy: GPCR dimers moving closer

scientific article published on 01 August 2010

Modulation of a brain voltage-gated K+ channel by syntaxin 1A requires the physical interaction of Gbetagamma with the channel.

scientific article

Modulation of beta1-adrenoceptor activity by domain-specific antibodies and heart failure-associated autoantibodies

scientific article published on 01 October 2000

Molecular basis of inverse agonism in a G protein-coupled receptor

scientific article published on 24 May 2005

Molecular basis of partial agonism at the neurotransmitter alpha2A-adrenergic receptor and Gi-protein heterotrimer

scientific article published on 20 June 2006

Molecular details of dimerization kinetics reveal negligible populations of transient µ-opioid receptor homodimers at physiological concentrations.

scientific article published on 16 May 2018

Molecular mechanisms of membrane receptor desensitization.

scientific article

Molecular mechanisms of receptor activation: real-time analysis by fluorescence resonance energy transfer.

scientific article

Monitoring receptor signaling by intramolecular FRET.

scientific article published on 04 October 2007

Multimodal function of the sweet taste receptor expressed in pancreatic β-cells: generation of diverse patterns of intracellular signals by sweet agonists.

scientific article published on 9 August 2013

Multiple pathways of rapid beta 2-adrenergic receptor desensitization. Delineation with specific inhibitors

scientific article published on February 1990

Mutation of Asn293 to Asp in transmembrane helix VI abolishes agonist-induced but not constitutive activity of the beta(2)-adrenergic receptor

scientific article published in December 2002

Mutations of Tyr326 in the beta 2-adrenoceptor disrupt multiple receptor functions.

scientific article

Neural cell adhesion molecules influence second messenger systems

scientific article

New directions in pharmacology

scientific article published on 01 December 1999

Nonequilibrium Activation of a G-Protein-Coupled Receptor ⬇️

scientific article published on February 29, 2012

Novel receptor-derived cyclopeptides to treat heart failure caused by anti-β1-adrenoceptor antibodies in a human-analogous rat model

scientific article

Novel single chain cAMP sensors for receptor-induced signal propagation.

scientific article published on July 2004

Novel somatic mutations in the catalytic subunit of the protein kinase A as a cause of adrenal Cushing's syndrome: a European multicentric study

scientific article published on 24 July 2014

Novel techniques for real-time monitoring of cGMP in living cells.

scientific article published on January 2009

Optical techniques to analyze real-time activation and signaling of G-protein-coupled receptors.

scientific article published on 11 February 2008

PKA catalytic subunit mutations in adrenocortical Cushing's adenoma impair association with the regulatory subunit.

scientific article

Partial agonist activity of bucindolol is dependent on the activation state of the human beta1-adrenergic receptor

scientific article published on 7 July 2003

Pathological autoantibodies in cardiomyopathy.

scientific article published on September 2008

Pentobarbital antagonizes the A1 adenosine receptor-mediated inhibition of hippocampal neurotransmitter release

scientific article published on 01 July 1987

Peptide G protein agonists from a phage display library.

scientific article

Peptide inhibitors of G protein-coupled receptor kinases

scientific article published on 01 October 2005

Persistent cAMP Signaling by Internalized LH Receptors in Ovarian Follicles

scientific article published on February 2016

Persistent cAMP signaling by internalized TSH receptors occurs in thyroid but not in HEK293 cells

scientific article published on 30 January 2012

Persistent cAMP-signals triggered by internalized G-protein-coupled receptors

scientific article

Pertussis toxin does not inhibit the alpha 1-adrenoceptor-mediated effect on inositol phosphate production in the heart

scientific article published on 01 February 1987

Pharmacological characterization of A1 adenosine receptors in isolated rat ventricular myocytes

scientific article published on September 1987

Pharmacology of NO:cGMP signal transduction

scientific article published on 01 July 1998

Phosducin influences sympathetic activity and prevents stress-induced hypertension in humans and mice

scientific article published on December 2009

Phosducin influences sympathetic activity and prevents stress-induced hypertension in humans and mice.

scientific article published on 22 December 2010

Phosducin is a protein kinase A-regulated G-protein regulator

scientific article published on July 2, 1992

Phosducin is a ubiquitous G-protein regulator.

scientific article published on September 1996

Phosducin, potential role in modulation of olfactory signaling

scientific article

Phosducin-like protein regulates G-protein betagamma folding by interaction with tailless complex polypeptide-1alpha: dephosphorylation or splicing of PhLP turns the switch toward regulation of Gbetagamma folding

scientific article (publication date: 20 May 2005)

Phospholamban pentamers attenuate PKA-dependent phosphorylation of monomers.

scientific article

Phosphorylation of GRK2 by protein kinase C abolishes its inhibition by calmodulin.

scientific article

Photoaffinity labeling of A1-adenosine receptors

scientific article published in November 1985

Pilot the pulse: controlling the multiplicity of receptor dynamics

scientific article published on 31 October 2014

Placental alpha(2)-adrenoceptors control vascular development at the interface between mother and embryo

scientific journal article

Polarization of migrating monocytic cells is independent of PI 3-kinase activity

scientific article (publication date: 2010)

Probing human beta 1- and beta 2-adrenoceptors with domain-specific fusion protein antibodies.

scientific article

Probing human β1- and β2-adrenoceptors with domain-specific fusion protein antibodies ⬇️

scientific article published on 01 September 1997

Progressive hypertrophy and heart failure in beta1-adrenergic receptor transgenic mice.

scientific article

Prolonged TSH receptor A subunit immunization of female mice leads to a long-term model of Graves' disease, tachycardia, and cardiac hypertrophy

scientific article published on 6 January 2015

Properties of cardiac alpha- and beta-adrenoceptors in spontaneously hypertensive rats

scientific article published on 01 October 1988

Protein kinase C switches the Raf kinase inhibitor from Raf-1 to GRK-2

scientific journal article

Protein kinase a transgenes: the many faces of cAMP

scientific article published on 01 November 2001

Publisher Correction: Internalized TSH receptors en route to the TGN induce local G-protein signaling and gene transcription

scientific article published in Nature Communications

Purification and functional characterization of beta-adrenergic receptor kinase expressed in insect cells.

scientific article

Quantification of the tissue levels and function of the G-protein regulator phosducin-like protein (PhlP).

scientific article published in November 2000

Quantitative Single-Residue Bioorthogonal Labeling of G Protein-Coupled Receptors in Live Cells

scientific article published on 23 May 2019

Radiation inactivation analysis of the A1 adenosine receptor of rat brain. Decrease in radiation inactivation size in the presence of guanine nucleotide

scientific article published in July 1989

Real-time monitoring of cAMP levels in living endothelial cells: thrombin transiently inhibits adenylyl cyclase 6.

scientific article published on 22 June 2009

Real-time monitoring of phosphodiesterase inhibition in intact cells.

scientific article

Real-time monitoring of somatostatin receptor-cAMP signaling in live pituitary.

scientific article published on 7 July 2010

Real-time monitoring of the PDE2 activity of live cells: hormone-stimulated cAMP hydrolysis is faster than hormone-stimulated cAMP synthesis

scientific article published on 22 November 2004

Real-time optical recording of beta1-adrenergic receptor activation reveals supersensitivity of the Arg389 variant to carvedilol

scientific article

Receptor signals come in waves

journal article; published in Nature on 2013-03-20

Receptor-ligand interactions studied with homogeneous fluorescence-based assays suitable for miniaturized screening

scientific article

Receptor-specific desensitization with purified proteins. Kinase dependence and receptor specificity of beta-arrestin and arrestin in the beta 2-adrenergic receptor and rhodopsin systems ⬇️

scientific article published on April 25, 1992

Regulation of beta-adrenergic receptor responsiveness modulation of receptor gene expression

scientific article published on 01 January 1999

Regulation of the inward rectifying properties of G-protein-activated inwardly rectifying K+ (GIRK) channels by Gbeta gamma subunits

scientific article published on 25 October 2002

Regulators of G-protein-mediated signalling

scientific article published on November 1996

Related GPCRs couple differently to Gs: preassociation between G protein and 5-HT7 serotonin receptor reveals movement of Gαs upon receptor activation.

scientific article published on 27 October 2017

Release and synthesis rates of catecholamines in hypothalamic, limbic and midbrain structures following intraventricular injection of β-endorphin in male rats ⬇️

scientific article published on December 21, 1981

Requirements and ontology for a G protein-coupled receptor oligomerization knowledge base

scientific article

Rotational diffusion of the α(2a) adrenergic receptor revealed by FlAsH labeling in living cells.

scientific article published on February 2011

Selectivity of beta-adrenergic receptor kinase 2 for G protein betagamma subunits

scientific article published on 01 January 1997

Self-limitation of intravenous tocolysis with beta2-adrenergic agonists is mediated through receptor G protein uncoupling

scientific article

Sensing G protein-coupled receptor activation.

scientific article published on 18 August 2010

Separation of solubilized A2 adenosine receptors of human platelets from non-receptor [3H]NECA binding sites by gel filtration

scientific article published on 01 January 1988

Sequential inter- and intrasubunit rearrangements during activation of dimeric metabotropic glutamate receptor 1.

scientific article

Sequestration and recycling of beta 2-adrenergic receptors permit receptor resensitization

scientific article published on 01 April 1995

Signaling by extracellular nucleotides and nucleosides

scientific article published on 01 November 2000

Signaling by internalized G-protein-coupled receptors.

scientific article published on 18 March 2010

Simultaneous optical measurements of cytosolic Ca2+ and cAMP in single cells

scientific article published on 19 September 2006

Single-Molecule Fluorescence Microscopy for the Analysis of Fast Receptor Dynamics.

scientific article published in January 2015

Single-molecule analysis of fluorescently labeled G-protein-coupled receptors reveals complexes with distinct dynamics and organization

scientific article

Single-molecule imaging reveals receptor-G protein interactions at cell surface hot spots.

scientific article

Site-specific, orthogonal labeling of proteins in intact cells with two small biarsenical fluorophores.

scientific article

Spatial and Temporal Aspects of Signaling by G-Protein-Coupled Receptors

scientific article

Stable overexpression of human ?2-adrenergic receptors in mammalian cells ⬇️

scientific article published on April 1, 1992

Stepwise activation of a class C GPCR begins with millisecond dimer rearrangement

scientific article published on 25 April 2019

Stimulating autoantibodies directed against the cardiac beta1-adrenergic receptor predict increased mortality in idiopathic cardiomyopathy

scientific article published in October 2006

Structure and Regulation of G Protein-Coupled Receptors: The β2-Adrenergic Receptor as a Model

scientific article published on January 1, 1991

Structure-Activity Relationships and Computational Investigations into the Development of Potent and Balanced Dual-Acting Butyrylcholinesterase Inhibitors and Human Cannabinoid Receptor 2 Ligands with Pro-Cognitive in Vivo Profiles.

scientific article

Study of interaction between agonists and asn293 in helix VI of human beta(2)-adrenergic receptor

scientific article published on 01 November 1999

Sweet taste receptor expressed in pancreatic beta-cells activates the calcium and cyclic AMP signaling systems and stimulates insulin secretion

scientific article

Synergistic effects of calcium-mobilizing agents and adenosine on histamine release from rat peritoneal mast cells

scientific article published on December 1989

Synthetic peptides of the hamster beta 2-adrenoceptor as substrates and inhibitors of the beta-adrenoceptor kinase

scientific article published on January 1990

Temporally resolved cAMP monitoring in endothelial cells uncovers a thrombin-induced [cAMP] elevation mediated via the Ca²+-dependent production of prostacyclin

scientific article published on 08 November 2010

The amino-terminal domain of G-protein-coupled receptor kinase 2 is a regulatory Gbeta gamma binding site

scientific article published on 16 December 2002

The future of pharmacology.

scientific article

The glycoprotein nature of A1 adenosine receptors

scientific article

The guanine nucleotide exchange factor Vav2 is a negative regulator of parathyroid hormone receptor/Gq signaling.

scientific article

The ins and outs of adrenergic signaling

scientific article published on 23 July 2015

The transcriptional repressor Nab1 is a specific regulator of pathological cardiac hypertrophy

scientific article published on 17 July 2005

Time-resolved fluorescence ligand binding for G protein-coupled receptors

scientific article published on 13 June 2013

Tocolytic therapy with fenoterol induces selective down-regulation of beta-adrenergic receptors in human myometrium

scientific article published on 01 April 1997

Trafficking and function of GPCRs in the endosomal compartment

scientific article published on 01 January 2015

Transgenic triadin 1 overexpression alters SR Ca2+ handling and leads to a blunted contractile response to beta-adrenergic agonists

scientific article published on April 2004

Turn-on switch in parathyroid hormone receptor by a two-step parathyroid hormone binding mechanism.

scientific article

Two affinity states of Ri adenosine receptors in brain membranes. Analysis of guanine nucleotide and temperature effects on radioligand binding.

scientific article published in July 1984

Vascular hypertrophy and increased P70S6 kinase in mice lacking the angiotensin II AT(2) receptor

scientific article published in November 2001

Visualization of β-adrenergic receptor dynamics and differential localization in cardiomyocytes

scientific article published in 2021

[3H]-8-cyclopentyl-1,3-dipropylxanthine binding to A1 adenosine receptors of intact rat ventricular myocytes

scientific article published on 01 September 1988

[Drugs--magic or science?]

scientific article published on 01 December 2000

[Mechanisms of the regulation of adrenergic beta-receptors]

scientific article published on 01 January 1996

beta(1)-Adrenergic receptor function, autoimmunity, and pathogenesis of dilated cardiomyopathy.

scientific article

beta-Arrestin-2 interaction and internalization of the human P2Y1 receptor are dependent on C-terminal phosphorylation sites.

scientific article

beta-Arrestin: a protein that regulates beta-adrenergic receptor function

scientific article

cAMP Signals in Drosophila Motor Neurons Are Confined to Single Synaptic Boutons.

scientific article published on October 2016

cAMP microdomains and L-type Ca2+ channel regulation in guinea-pig ventricular myocytes

scientific article published on 08 February 2007

β-Adrenergic receptor stimulation causes cardiac hypertrophy via a Gβγ/Erk-dependent pathway

scientific article published on July 27, 2012

β-Arrestin biosensors reveal a rapid, receptor-dependent activation/deactivation cycle

scientific article published on 23 March 2016

β-Myosin heavy chain variant Val606Met causes very mild hypertrophic cardiomyopathy in mice, but exacerbates HCM phenotypes in mice carrying other HCM mutations

scientific article

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