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List of works by Yuan Zhang

3',4'-Bis-difluoromethoxycinnamoylanthranilate (FT061): an orally-active antifibrotic agent that reduces albuminuria in a rat model of progressive diabetic nephropathy.

scientific article published on 8 October 2013

3′,4′-Dihydroxyflavonol Antioxidant Attenuates Diastolic Dysfunction and Cardiac Remodeling in Streptozotocin-Induced Diabetic m(Ren2)27 Rats ⬇️

scientific article published on July 28, 2011

A new anti-fibrotic drug attenuates cardiac remodeling and systolic dysfunction following experimental myocardial infarction

scientific article published on 06 December 2012

A purpose-synthesised anti-fibrotic agent attenuates experimental kidney diseases in the rat

scientific article

Aliskiren increases bradykinin and tissue kallikrein mRNA levels in the heart

scientific article published in September 2011

Atrial Remodeling in an Ovine Model of Anthracycline-Induced Nonischemic Cardiomyopathy: Remodeling of the Same Sort

scientific article published on 01 February 2011

Atrial arrhythmia in ageing spontaneously hypertensive rats: unraveling the substrate in hypertension and ageing

scientific article

Cardiac Repair With a Novel Population of Mesenchymal Stem Cells Resident in the Human Heart

scientific article published on 16 July 2015

Cells expressing the stem cell factor receptor, c-kit, contribute to neoangiogenesis in diabetes

scientific article published in May 2005

Characterization of cardiac remodeling in a large animal "one-kidney, one-clip" hypertensive model

scientific article published in April 2010

Chloride channel ClC-5 binds to aspartyl aminopeptidase to regulate renal albumin endocytosis

scientific article published on 13 January 2015

Culture-modified bone marrow cells attenuate cardiac and renal injury in a chronic kidney disease rat model via a novel antifibrotic mechanism

scientific article (publication date: 2010)

Effects on protein kinase C-beta inhibition on glomerular vascular endothelial growth factor expression and endothelial cells in advanced experimental diabetic nephropathy

scientific article published on 23 May 2007

Evaluation and optimization of antifibrotic activity of cinnamoyl anthranilates

scientific article published on 7 October 2009

Expression, localization, and function of the thioredoxin system in diabetic nephropathy

scientific article published on 11 February 2009

FT011, a Novel Cardiorenal Protective Drug, Reduces Inflammation, Gliosis and Vascular Injury in Rats with Diabetic Retinopathy

scientific article

FT23, an orally active antifibrotic compound, attenuates structural and functional abnormalities in an experimental model of diabetic cardiomyopathy

scientific article published in August 2012

Fas-induced apoptosis is a feature of progressive diabetic nephropathy in transgenic (mRen-2)27 rats: attenuation with renin-angiotensin blockade

scientific article published in February 2004

High glucose induces Smad activation via the transcriptional coregulator p300 and contributes to cardiac fibrosis and hypertrophy

scientific article

High glucose induces macrophage inflammatory protein-3 alpha in renal proximal tubule cells via a transforming growth factor-beta 1 dependent mechanism

scientific article

High glucose-induced thioredoxin-interacting protein in renal proximal tubule cells is independent of transforming growth factor-beta1.

scientific article

Hypertension and atrial fibrillation: evidence of progressive atrial remodeling with electrostructural correlate in a conscious chronically instrumented ovine model

scientific article published on 11 May 2010

Impaired cardiac anti-oxidant activity in diabetes: human and correlative experimental studies

scientific article published on 13 June 2014

In vivo visualization of albumin degradation in the proximal tubule

scientific article published on 17 September 2008

Inhibition of protein kinase C reduces left ventricular fibrosis and dysfunction following myocardial infarction

scientific article published on 01 August 2005

Inhibition of the epidermal growth factor receptor preserves podocytes and attenuates albuminuria in experimental diabetic nephropathy ⬇️

scientific article published on August 1, 2011

Intervention with tranilast attenuates renal pathology and albuminuria in advanced experimental diabetic nephropathy

scientific article published on 01 January 2003

Macrophage infiltration and cellular proliferation in the non-ischemic kidney and heart following prolonged unilateral renal ischemia

scientific article published on 15 June 2007

Mast cell infiltration and chemokine expression in progressive renal disease

scientific article published in September 2003

Myocardial infarction impairs renal function, induces renal interstitial fibrosis, and increases renal KIM-1 expression: implications for cardiorenal syndrome

scientific article published on 24 February 2012

Nitrosative Stress as a Modulator of Inflammatory Change in a Model of Takotsubo Syndrome

scientific article published on 18 April 2018

Obesity results in progressive atrial structural and electrical remodeling: Implications for atrial fibrillation

scientific article published on 01 September 2012

Protein kinase C beta inhibition attenuates the progression of experimental diabetic nephropathy in the presence of continued hypertension

scientific article published in February 2003

Protein kinase C-beta inhibition attenuates the progression of nephropathy in non-diabetic kidney disease

scientific article published on 20 January 2009

Protein kinase Cbeta inhibition attenuates osteopontin expression, macrophage recruitment, and tubulointerstitial injury in advanced experimental diabetic nephropathy

scientific article published on 20 April 2005

Relaxin ameliorates fibrosis in experimental diabetic cardiomyopathy

scientific article published on 03 April 2008

Renal expression and localization of the facilitative glucose transporters GLUT1 and GLUT12 in animal models of hypertension and diabetic nephropathy

scientific article

Role of Kruppel-like factor 6 in transforming growth factor-beta1-induced epithelial-mesenchymal transition of proximal tubule cells

scientific article published on 27 August 2008

Role of the eNOS-NO system in regulating the antiproteinuric effects of VEGF receptor 2 inhibition in diabetes

scientific article published on 22 August 2013

Short-term hypertension is associated with the development of atrial fibrillation substrate: a study in an ovine hypertensive model.

scientific article published on 2 December 2009

Soluble epoxide hydrolase inhibition exerts beneficial anti-remodeling actions post-myocardial infarction

scientific article published on 10 January 2012

Targeted inhibition of activin receptor-like kinase 5 signaling attenuates cardiac dysfunction following myocardial infarction

scientific article published on 12 February 2010

The anti-fibrotic hormone relaxin is not reno-protective, despite being active, in an experimental model of type 1 diabetes

scientific article published on 01 September 2013

The differential regulation of Smad7 in kidney tubule cells by connective tissue growth factor and transforming growth factor-beta1.

scientific article published on June 2007

Thioredoxin-interacting protein: a potential therapeutic target for treatment of progressive fibrosis in diabetic nephropathy

scientific article

Tranilast ameliorates experimental mesangial proliferative glomerulonephritis

scientific article published on 15 May 2008

Tranilast attenuates cardiac matrix deposition in experimental diabetes: role of transforming growth factor-beta

scientific article published in February 2005

Tranilast attenuates diastolic dysfunction and structural injury in experimental diabetic cardiomyopathy

scientific article published on 24 August 2007

Tranilast attenuates structural and functional aspects of renal injury in the remnant kidney model

scientific article published in October 2004

Tranilast attenuates the up-regulation of thioredoxin-interacting protein and oxidative stress in an experimental model of diabetic nephropathy

scientific article published on 23 June 2010

Transforming growth factor-beta in human diabetic nephropathy: effects of ACE inhibition.

scientific article

Widespread Coronary Dysfunction in the Absence of HDL Receptor SR-B1 in an Ischemic Cardiomyopathy Mouse Model

scientific article published on 22 December 2017

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