List of works - Kurt von Figura

A general binding mechanism for all human sulfatases by the formylglycine-generating enzyme

scientific article

A new type of congenital disorders of glycosylation (CDG-Ii) provides new insights into the early steps of dolichol-linked oligosaccharide biosynthesis

scientific article

Crystal structure of human pFGE, the paralog of the Calpha-formylglycine-generating enzyme

scientific article

Defective oligomerization of arylsulfatase a as a cause of its instability in lysosomes and metachromatic leukodystrophy

scientific article

Deficiency of GDP-Man:GlcNAc2-PP-dolichol mannosyltransferase causes congenital disorder of glycosylation type Ik.

scientific article

Deficiency of UDP-galactose:N-acetylglucosamine beta-1,4-galactosyltransferase I causes the congenital disorder of glycosylation type IId.

scientific article

Deficiency of dolichyl-P-Man:Man7GlcNAc2-PP-dolichyl mannosyltransferase causes congenital disorder of glycosylation type Ig

scientific article

Disturbed cholesterol traffic but normal proteolytic function in LAMP-1/LAMP-2 double-deficient fibroblasts

scientific article

Efficacy of enzyme replacement therapy in alpha-mannosidosis mice: a preclinical animal study

scientific article

Expression, localization, structural, and functional characterization of pFGE, the paralog of the Calpha-formylglycine-generating enzyme

scientific article

Granzyme-mediated cytotoxicity does not involve the mannose 6-phosphate receptors on target cells

scientific article published on 25 February 2004

Heparan sulfate 6-O-endosulfatases: discrete in vivo activities and functional co-operativity

scientific article

Identification of formylglycine in sulfatases by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry

scientific article

Identification of novel lysosomal matrix proteins by proteome analysis

scientific article published in October 2005

Involvement of cathepsin E in exogenous antigen processing in primary cultured murine microglia

scientific journal article

LIMP-2/LGP85 deficiency causes ureteric pelvic junction obstruction, deafness and peripheral neuropathy in mice

scientific article (publication date: 15 March 2003)

Locating the anomalous scatterer substructures in halide and sulfur phasing

scientific article

Mannose 6-phosphate receptors, Niemann-Pick C2 protein, and lysosomal cholesterol accumulation

scientific article published on 21 September 2005

Molecular analysis of SUMF1 mutations: stability and residual activity of mutant formylglycine-generating enzyme determine disease severity in multiple sulfatase deficiency

scientific article published on January 2008

Molecular basis for multiple sulfatase deficiency and mechanism for formylglycine generation of the human formylglycine-generating enzyme

scientific article

Molecular basis of multiple sulfatase deficiency, mucolipidosis II/III and Niemann-Pick C1 disease - Lysosomal storage disorders caused by defects of non-lysosomal proteins

scientific article published on 10 December 2008

Molecular characterization of the human Calpha-formylglycine-generating enzyme

scientific article published on 18 January 2005

Molecular characterization of the hypothetical 66.3-kDa protein in mouse: lysosomal targeting, glycosylation, processing and tissue distribution

scientific journal article

Multiple sulfatase deficiency is caused by mutations in the gene encoding the human C(alpha)-formylglycine generating enzyme

scientific journal article

Paralog of the formylglycine-generating enzyme--retention in the endoplasmic reticulum by canonical and noncanonical signals

scientific article published on 6 February 2008

Participation of autophagy in storage of lysosomes in neurons from mouse models of neuronal ceroid-lipofuscinoses (Batten disease).

scientific article

Phosphorylation of the AP2 mu subunit by AAK1 mediates high affinity binding to membrane protein sorting signals

scientific article

Structural requirements for interactions between leucine-sorting signals and clathrin-associated adaptor protein complex AP3

scientific article (publication date: 6 December 2002)

Targeted disruption of the mouse phosphomannomutase 2 gene causes early embryonic lethality

scientific article

The disintegrin/metalloprotease ADAM 10 is essential for Notch signalling but not for alpha-secretase activity in fibroblasts

scientific article

The human SUMF1 gene, required for posttranslational sulfatase modification, defines a new gene family which is conserved from pro- to eukaryotes ⬇️

scientific article published on October 16, 2003

The non-catalytic N-terminal extension of formylglycine-generating enzyme is required for its biological activity and retention in the endoplasmic reticulum

scientific article

The tyrosine motifs of Lamp 1 and LAP determine their direct and indirect targetting to lysosomes

scientific article (publication date: 2002)

Thyroid functions of mouse cathepsins B, K, and L.

scientific article

List of works by Kurt von Figura

A general binding mechanism for all human sulfatases by the formylglycine-generating enzyme

A new type of congenital disorders of glycosylation (CDG-Ii) provides new insights into the early steps of dolichol-linked oligosaccharide biosynthesis

Crystal structure of human pFGE, the paralog of the Calpha-formylglycine-generating enzyme

Defective oligomerization of arylsulfatase a as a cause of its instability in lysosomes and metachromatic leukodystrophy

Deficiency of GDP-Man:GlcNAc2-PP-dolichol mannosyltransferase causes congenital disorder of glycosylation type Ik.

Deficiency of UDP-galactose:N-acetylglucosamine beta-1,4-galactosyltransferase I causes the congenital disorder of glycosylation type IId.

Deficiency of dolichyl-P-Man:Man7GlcNAc2-PP-dolichyl mannosyltransferase causes congenital disorder of glycosylation type Ig

Disturbed cholesterol traffic but normal proteolytic function in LAMP-1/LAMP-2 double-deficient fibroblasts

Efficacy of enzyme replacement therapy in alpha-mannosidosis mice: a preclinical animal study

Expression, localization, structural, and functional characterization of pFGE, the paralog of the Calpha-formylglycine-generating enzyme

Granzyme-mediated cytotoxicity does not involve the mannose 6-phosphate receptors on target cells

Heparan sulfate 6-O-endosulfatases: discrete in vivo activities and functional co-operativity

Identification of formylglycine in sulfatases by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry

Identification of novel lysosomal matrix proteins by proteome analysis

Involvement of cathepsin E in exogenous antigen processing in primary cultured murine microglia

LIMP-2/LGP85 deficiency causes ureteric pelvic junction obstruction, deafness and peripheral neuropathy in mice

Locating the anomalous scatterer substructures in halide and sulfur phasing

Mannose 6-phosphate receptors, Niemann-Pick C2 protein, and lysosomal cholesterol accumulation

Molecular analysis of SUMF1 mutations: stability and residual activity of mutant formylglycine-generating enzyme determine disease severity in multiple sulfatase deficiency

Molecular basis for multiple sulfatase deficiency and mechanism for formylglycine generation of the human formylglycine-generating enzyme

Molecular basis of multiple sulfatase deficiency, mucolipidosis II/III and Niemann-Pick C1 disease - Lysosomal storage disorders caused by defects of non-lysosomal proteins

Molecular characterization of the human Calpha-formylglycine-generating enzyme

Molecular characterization of the hypothetical 66.3-kDa protein in mouse: lysosomal targeting, glycosylation, processing and tissue distribution

Multiple sulfatase deficiency is caused by mutations in the gene encoding the human C(alpha)-formylglycine generating enzyme

Paralog of the formylglycine-generating enzyme--retention in the endoplasmic reticulum by canonical and noncanonical signals

Participation of autophagy in storage of lysosomes in neurons from mouse models of neuronal ceroid-lipofuscinoses (Batten disease).

Phosphorylation of the AP2 mu subunit by AAK1 mediates high affinity binding to membrane protein sorting signals

Structural requirements for interactions between leucine-sorting signals and clathrin-associated adaptor protein complex AP3

Targeted disruption of the mouse phosphomannomutase 2 gene causes early embryonic lethality

The disintegrin/metalloprotease ADAM 10 is essential for Notch signalling but not for alpha-secretase activity in fibroblasts

The human SUMF1 gene, required for posttranslational sulfatase modification, defines a new gene family which is conserved from pro- to eukaryotes ⬇️

The non-catalytic N-terminal extension of formylglycine-generating enzyme is required for its biological activity and retention in the endoplasmic reticulum

The tyrosine motifs of Lamp 1 and LAP determine their direct and indirect targetting to lysosomes

Thyroid functions of mouse cathepsins B, K, and L.