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List of works by Deborah M Proctor

A Pleiotropic Missense Variant in SLC39A8 Is Associated With Crohn's Disease and Human Gut Microbiome Composition

scientific article

A chronic oral reference dose for hexavalent chromium‐induced intestinal cancer ⬇️

scientific article published on August 14, 2013

A genome-wide scan of Ashkenazi Jewish Crohn's disease suggests novel susceptibility loci

scientific journal article

A response to "A quantitative assessment of the carcinogenicity of hexavalent chromium by the oral route and its relevance to human exposure"

scientific article published on 12 February 2011

A review of the genotoxic, mutagenic, and carcinogenic potentials of several lower acrylates

scientific article published on 21 April 2018

A robust method for assessing chemically induced mutagenic effects in the oral cavity of transgenic Big Blue® rats

scientific article published on 13 May 2015

An Adverse Outcome Pathway (AOP) for forestomach tumors induced by non-genotoxic initiating events

scientific article published on 21 April 2018

An adverse outcome pathway for small intestinal tumors in mice involving chronic cytotoxicity and regenerative hyperplasia: a case study with hexavalent chromium, captan, and folpet

scientific article published on 04 November 2020

Appendectomy does not decrease the risk of future colectomy in UC: results from a large cohort and meta-analysis

scientific article published on 13 April 2016

Application of the U.S. EPA mode of action Framework for purposes of guiding future research: a case study involving the oral carcinogenicity of hexavalent chromium

scientific article (publication date: 2011)

Assessment of Cr(VI)-induced cytotoxicity and genotoxicity using high content analysis

scientific article

Assessment of K-Ras mutant frequency and micronucleus incidence in the mouse duodenum following 90-days of exposure to Cr(VI) in drinking water.

scientific article published on 9 April 2013

Assessment of genotoxic potential of Cr(VI) in the mouse duodenum: an in silico comparison with mutagenic and nonmutagenic carcinogens across tissues

scientific article published on 15 June 2012

Assessment of the mode of action for hexavalent chromium-induced lung cancer following inhalation exposures

scientific article published on 28 August 2014

Assessment of the mode of action underlying development of forestomach tumors in rodents following oral exposure to ethyl acrylate and relevance to humans

scientific article published on 05 May 2018

Assessment of the mode of action underlying development of rodent small intestinal tumors following oral exposure to hexavalent chromium and relevance to humans

scientific article

Assessment of the mutagenic potential of Cr(VI) in the oral mucosa of Big Blue® transgenic F344 rats

scientific article

Assessment of the mutagenic potential of hexavalent chromium in the duodenum of big blue® rats

scientific article published on 4 July 2017

Bioaccessibility and relative oral bioavailability of cobalt and nickel in residential soil and dust affected by metal grinding operations

scientific article published on 22 December 2018

Comparison of Toxicity and Recovery in the Duodenum of B6C3F1 Mice Following Treatment with Intestinal Carcinogens Captan, Folpet, and Hexavalent Chromium

scientific article published in January 2017

Comparison of in vivo genotoxic and carcinogenic potency to augment mode of action analysis: Case study with hexavalent chromium.

scientific article published on 6 March 2016

Comparison of the effects of hexavalent chromium in the alimentary canal of F344 rats and B6C3F1 mice following exposure in drinking water: implications for carcinogenic modes of action.

scientific article published on 19 October 2011

Development of linear and threshold no significant risk levels for inhalation exposure to titanium dioxide using systematic review and mode of action considerations

scientific article

Duodenal crypt health following exposure to Cr(VI): Micronucleus scoring, γ-H2AX immunostaining, and synchrotron X-ray fluorescence microscopy.

scientific article published on 14 May 2015

Erratum: Corrigendum: Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47

scholarly article published in Nature Genetics

Erratum: Corrigendum: Ulcerative colitis-risk loci on chromosomes 1p36 and 12q15 found by genome-wide association study

scholarly article published in Nature Genetics

Estimating historical occupational exposure to airborne hexavalent chromium in a chromate production plant: 1940--1972.

scientific article published in November 2004

Exposure to environmentally-relevant concentrations of hexavalent chromium does not induce ovarian toxicity in mice

scientific article published on 08 July 2020

Genome-wide gene expression effects in B6C3F1 mouse intestinal epithelia following 7 and 90days of exposure to hexavalent chromium in drinking water

scientific article published on December 2011

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

scientific article

Hexavalent chromium and stomach cancer: a systematic review and meta-analysis

scientific article published on 01 February 2019

Hexavalent chromium reduction kinetics in rodent stomach contents

scientific article published on 08 June 2012

High concentrations of hexavalent chromium in drinking water alter iron homeostasis in F344 rats and B6C3F1 mice

scientific article published on 10 January 2014

High-Throughput Screening Data Interpretation in the Context of In Vivo Transcriptomic Responses to Oral Cr(VI) Exposure

scientific article

Improved physiologically based pharmacokinetic model for oral exposures to chromium in mice, rats, and humans to address temporal variation and sensitive populations

scientific article

Inhalation cancer risk assessment of cobalt metal

scientific article published on 10 May 2016

Inhalation cancer risk assessment of hexavalent chromium based on updated mortality for Painesville chromate production workers

scientific article published on 16 December 2015

Integration of mechanistic and pharmacokinetic information to derive oral reference dose and margin-of-exposure values for hexavalent chromium.

scientific article published on 24 October 2017

Investigation of the mode of action underlying the tumorigenic response induced in B6C3F1 mice exposed orally to hexavalent chromium.

scientific article

Letter to the Editor Regarding Banu et al. (2018). Chromium Accumulation on Human Placental Oxidative Stress and Apoptosis

scientific article published on 01 October 2018

Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47

scientific journal article

Mode-of-action framework for evaluating the relevance of rodent forestomach tumors in cancer risk assessment

scientific article published on 10 April 2007

Need for improved science in standard setting for hexavalent chromium

scientific article published on 01 April 1999

Occupational exposure to hexavalent chromium and cancers of the gastrointestinal tract: a meta-analysis

scientific article published on 28 April 2010

Phenotypic and genotypic characteristics of inflammatory bowel disease in French Canadians: comparison with a large North American repository

scientific article published on 09 June 2009

Physiologically based pharmacokinetic model for humans orally exposed to chromium.

scientific article published on 17 April 2013

Physiologically based pharmacokinetic model for rats and mice orally exposed to chromium.

scientific article published on 6 September 2012

Reduction of hexavalent chromium by fasted and fed human gastric fluid. I. Chemical reduction and mitigation of mutagenicity

scientific article published on 9 July 2016

Reduction of hexavalent chromium by fasted and fed human gastric fluid. II. Ex vivo gastric reduction modeling

scientific article published on 7 July 2016

Relationship between proximal Crohn's disease location and disease behavior and surgery: a cross-sectional study of the IBD Genetics Consortium

scientific article

Review of transcriptomic responses to hexavalent chromium exposure in lung cells supports a role of epigenetic mediators in carcinogenesis

scientific article published on 25 January 2019

Synchrotron-based imaging of chromium and γ-H2AX immunostaining in the duodenum following repeated exposure to Cr(VI) in drinking water

scientific article

Ten factors for considering the mode of action of Cr(VI)-induced gastrointestinal tumors in rodents

scientific article

The effects of perchlorate, nitrate, and thiocyanate on free thyroxine for potentially sensitive subpopulations of the 2001-2002 and 2007-2008 National Health and Nutrition Examination Surveys

scientific article published on 23 October 2013

The prevalence of chromium allergy in the United States and its implications for setting soil cleanup: a cost-effectiveness case study

scientific article published on 01 August 1998

Transcriptomic responses in the oral cavity of F344 rats and B6C3F1 mice following exposure to Cr(VI): Implications for risk assessment.

scientific article

Ulcerative colitis-risk loci on chromosomes 1p36 and 12q15 found by genome-wide association study

scientific article

Workplace airborne hexavalent chromium concentrations for the Painesville, Ohio, chromate production plant (1943-1971).

scientific article published in June 2003

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