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List of works by Nancy L Saccone

A Systematic single nucleotide polymorphism screen to fine-map alcohol dependence genes on chromosome 7 identifies association with a novel susceptibility gene ACN9

scientific article published on 27 December 2007

A genome-wide association study of alcohol dependence

scientific article

A genomic scan for habitual smoking in families of alcoholics: common and specific genetic factors in substance dependence

scientific article published in January 2004

A large-scale genome-wide association study meta-analysis of cannabis use disorder

scientific article published on 20 October 2020

A meta-analysis of two genome-wide association studies to identify novel loci for maximum number of alcoholic drinks

scientific journal article

A multiancestry study identifies novel genetic associations with CHRNA5 methylation in human brain and risk of nicotine dependence

scientific article

A putative causal relationship between genetically determined female body shape and posttraumatic stress disorder

scientific article published on 27 November 2017

A risk allele for nicotine dependence in CHRNA5 is a protective allele for cocaine dependence

scientific article published on 02 June 2008

Age and birth cohort effects on rates of alcohol dependence

scientific article published in January 2003

Are genetic variants for tobacco smoking associated with cannabis involvement?

scientific article published on 4 March 2015

Assessment of genotype imputation performance using 1000 Genomes in African American studies

scientific article

Association of the OPRM1 Variant rs1799971 (A118G) with Non-Specific Liability to Substance Dependence in a Collaborative de novo Meta-Analysis of European-Ancestry Cohorts

scientific article

Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use

scientific article published on 14 January 2019

Beyond cigarettes per day. A genome-wide association study of the biomarker carbon monoxide

scientific article

CHRNA5 risk variant predicts delayed smoking cessation and earlier lung cancer diagnosis--a meta-analysis

scientific article published in May 2015

CHRNB3 is more strongly associated with Fagerström test for cigarette dependence-based nicotine dependence than cigarettes per day: phenotype definition changes genome-wide association studies results

scientific article

CYP2A6 metabolism in the development of smoking behaviors in young adults

scientific article published on 29 December 2016

Cis-Expression Quantitative Trait Loci Mapping Reveals Replicable Associations with Heroin Addiction in OPRM1

scientific article published on 29 January 2015

Common polymorphisms in FMO1 are associated with nicotine dependence

scientific article published on July 2011

Correction: Novel Genetic Locus Implicated for HIV-1 Acquisition with Putative Regulatory Links to HIV Replication and Infectivity: A Genome-Wide Association Study

scientific article published on 29 May 2015

Dissecting the genetic overlap of smoking behaviors, lung cancer, and chronic obstructive pulmonary disease: A focus on nicotinic receptors and nicotine metabolizing enzyme

scientific article published on 16 August 2020

Dissection of the phenotypic and genotypic associations with nicotinic dependence

scientific article published on 18 November 2011

Distinct loci in the CHRNA5/CHRNA3/CHRNB4 gene cluster are associated with onset of regular smoking

scientific article

Endophenotypes successfully lead to gene identification: results from the collaborative study on the genetics of alcoholism

scientific article

Expanding the genetic architecture of nicotine dependence and its shared genetics with multiple traits

scientific article published on 03 November 2020

Functional Variants in TAS2R38 and TAS2R16 Influence Alcohol Consumption in High-Risk Families of African-American Origin

article

Further evidence for an association between the gamma-aminobutyric acid receptor A, subunit 4 genes on chromosome 4 and Fagerström Test for Nicotine Dependence

scientific article published on March 2009

Gamma-aminobutyric acid receptor genes and nicotine dependence: evidence for association from a case-control study

scientific article published in June 2008

Imputation across genotyping arrays for genome-wide association studies: assessment of bias and a correction strategy

scientific article published on 22 January 2013

In search of causal variants: refining disease association signals using cross-population contrasts

scientific article

Incorporating age at onset of smoking into genetic models for nicotine dependence: evidence for interaction with multiple genes

scientific article

Increased genetic vulnerability to smoking at CHRNA5 in early-onset smokers

scientific article

International meta-analysis of PTSD genome-wide association studies identifies sex- and ancestry-specific genetic risk loci

scientific article published on 08 October 2019

Interplay of Genetic Risk Factors and Parent Monitoring in Risk for Nicotine Dependence

scientific article

Is the Fagerström test for nicotine dependence invariant across secular trends in smoking? A question for cross-birth cohort analysis of nicotine dependence.

scientific article published on 6 February 2018

KAT2B polymorphism identified for drug abuse in African Americans with regulatory links to drug abuse pathways in human prefrontal cortex

scientific article published on 23 July 2015

Largest genome-wide association study for PTSD identifies genetic risk loci in European and African ancestries and implicates novel biological pathways

article published in 2018

Leveraging genome-wide data to investigate differences between opioid use vs. opioid dependence in 41,176 individuals from the Psychiatric Genomics Consortium

scientific article published on 26 February 2020

Linkage scan for quantitative traits identifies new regions of interest for substance dependence in the Collaborative Study on the Genetics of Alcoholism (COGA) sample

scientific article

Multiple distinct CHRNB3-CHRNA6 variants are genetic risk factors for nicotine dependence in African Americans and European Americans

scientific article published on 18 February 2014

Multiple distinct risk loci for nicotine dependence identified by dense coverage of the complete family of nicotinic receptor subunit (CHRN) genes

scientific article published on June 2009

Multiple independent loci at chromosome 15q25.1 affect smoking quantity: a meta-analysis and comparison with lung cancer and COPD.

scientific article

Nicotine dependence and comorbid psychiatric disorders: examination of specific genetic variants in the CHRNA5-A3-B4 nicotinic receptor genes

scientific article

Novel genetic locus implicated for HIV-1 acquisition with putative regulatory links to HIV replication and infectivity: a genome-wide association study

scientific article

Peer smoking and the nicotinic receptor genes: an examination of genetic and environmental risks for nicotine dependence

scientific article (publication date: November 2010)

Pharmacotherapy effects on smoking cessation vary with nicotine metabolism gene (CYP2A6).

scientific article

Protocol for a collaborative meta-analysis of 5-HTTLPR, stress, and depression

scientific article

Rare missense variants in CHRNB3 and CHRNA3 are associated with risk of alcohol and cocaine dependence

scientific article published on 20 September 2013

Risk for nicotine dependence and lung cancer is conferred by mRNA expression levels and amino acid change in CHRNA5.

scientific article published on 14 May 2009

Shared genetic risk between eating disorder- and substance-use-related phenotypes: Evidence from genome-wide association studies

scientific article published on 16 February 2020

Smoking and genetic risk variation across populations of European, Asian, and African American ancestry--a meta-analysis of chromosome 15q25.

scientific article

Supplementing high-density SNP microarrays for additional coverage of disease-related genes: addiction as a paradigm

scientific article

Systematic biological prioritization after a genome-wide association study: an application to nicotine dependence

scientific article published on 19 June 2008

The CHRNA5-CHRNA3-CHRNB4 nicotinic receptor subunit gene cluster affects risk for nicotine dependence in African-Americans and in European-Americans

scientific article

Trans-ancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders

scholarly article published 10 March 2018

Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders

scientific article published on 26 November 2018

Uncovering hidden variance: pair-wise SNP analysis accounts for additional variance in nicotine dependence

scientific article

Variants in nicotinic receptors and risk for nicotine dependence

scientific article published on 02 June 2008

Variants near CHRNB3-CHRNA6 are associated with DSM-5 cocaine use disorder: evidence for pleiotropy

scientific article published on 28 March 2014

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