List of works - Sabine Costagliola

A conserved Asn in TM7 of the thyrotropin receptor is a common requirement for activation by both mutations and its natural agonist.

scientific article

A family with a novel TSH receptor activating germline mutation (p.Ala485Val).

scientific article published on 4 January 2008

A lack of thyroid hormones rather than excess thyrotropin causes abnormal skeletal development in hypothyroidism

scientific article

A molecular dissection of the glycoprotein hormone receptors.

scientific article published on March 2004

A mutation in the follicle-stimulating hormone receptor as a cause of familial spontaneous ovarian hyperstimulation syndrome.

scientific article published on March 2004

A physiological role for the posttranslational cleavage of the thyrotropin receptor?

scientific article published on January 2004

Activation of the cAMP pathway by the TSH receptor involves switching of the ectodomain from a tethered inverse agonist to an agonist

scientific article published on 01 April 2002

Allosteric modulation of binding properties between units of chemokine receptor homo- and hetero-oligomers.

scientific article published on 7 February 2006

Allosteric properties of G protein-coupled receptor oligomers

scientific article published on 27 June 2007

An activation switch in the rhodopsin family of G protein-coupled receptors: the thyrotropin receptor

scientific article

Autosomal-dominant non-autoimmune hyperthyroidism presenting with neuromuscular symptoms

scientific article published in August 2005

Characterization of a novel loss of function mutation of PAX8 in a familial case of congenital hypothyroidism with in-place, normal-sized thyroid

scientific article

Choline head groups stabilize the matrix loop regions of the ATP/ADP carrier ScAAC2.

scientific article published in January 2003

Deletion of the RNaseIII enzyme dicer in thyroid follicular cells causes hypothyroidism with signs of neoplastic alterations

scientific article

Delineation of the discontinuous-conformational epitope of a monoclonal antibody displaying full in vitro and in vivo thyrotropin activity

scientific article published on 19 August 2004

Evidence for activity-regulated hormone-binding cooperativity across glycoprotein hormone receptor homomers

scientific article published in Nature Communications

Functional zebrafish studies based on human genotyping point to netrin-1 as a link between aberrant cardiovascular development and thyroid dysgenesis

scientific article

G protein-coupled receptors: mutations and endocrine diseases

scientific article published on 08 February 2011

GRIS: glycoprotein-hormone receptor information system

scientific article published on 16 March 2006

Generation of Functional Thyroid Tissue Using 3D-Based Culture of Embryonic Stem Cells

scientific article published on 01 January 2017

Generation of functional thyroid from embryonic stem cells

scientific article published on 10 October 2012

Genetic predictors of ovarian hyperstimulation syndrome in women undergoing in vitro fertilization

scientific article published on 01 November 2006

Germline mutations of TSH receptor gene as cause of nonautoimmune subclinical hypothyroidism.

scientific article

Glycoprotein hormone receptors: determinants in leucine-rich repeats responsible for ligand specificity

scientific article

Glycoprotein hormone receptors: link between receptor homodimerization and negative cooperativity

scientific article

Identification and characterization of an endogenous chemotactic ligand specific for FPRL2

scientific article

Identification of the first germline mutation in the extracellular domain of the follitropin receptor responsible for spontaneous ovarian hyperstimulation syndrome

scientific article published on 01 January 2008

Lethal respiratory failure and mild primary hypothyroidism in a term girl with a de novo heterozygous mutation in the TITF1/NKX2.1 gene

scientific article

Lysine 183 and glutamic acid 157 of the TSH receptor: two interacting residues with a key role in determining specificity toward TSH and human CG.

scientific article

Modulation of ligand selectivity associated with activation of the transmembrane region of the human follitropin receptor.

scientific article published on 27 May 2004

Monoclonal antibodies with thyroid stimulating activity, at last

scientific article published on 01 December 2002

New model systems to illuminate thyroid organogenesis. Part I: an update on the zebrafish toolbox

scientific article published on 03 December 2013

Novel inactivating follicle-stimulating hormone receptor mutations in a patient with premature ovarian insufficiency identified by next-generation sequencing gene panel analysis

scientific article published on 22 August 2020

Ovarian hyperstimulation syndrome due to a mutation in the follicle-stimulating hormone receptor.

scientific article published in August 2003

Prediction of severity of symptoms in iatrogenic ovarian hyperstimulation syndrome by follicle-stimulating hormone receptor Ser680Asn polymorphism

scientific article published in December 2004

Protein tyrosine-O-sulfation analysis by exhaustive product ion scanning with minimum collision offset in a NanoESI Q-TOF tandem mass spectrometer.

scientific article published in September 2004

Single-cell transcriptome analysis reveals thyrocyte diversity in the zebrafish thyroid gland

scientific article published on 03 November 2020

Small amplified RNA-SAGE: an alternative approach to study transcriptome from limiting amount of mRNA

scientific article

Specificity and promiscuity of gonadotropin receptors.

scientific article

Structural differences in the hinge region of the glycoprotein hormone receptors: evidence from the sulfated tyrosine residues

scientific article published on 10 August 2006

TSH receptor function is required for normal thyroid differentiation in zebrafish

scientific article

Transgenic zebrafish illuminate the dynamics of thyroid morphogenesis and its relationship to cardiovascular development

scientific article published on 26 September 2012

Understanding ovarian hyperstimulation syndrome

scientific article

List of works by Sabine Costagliola

A conserved Asn in TM7 of the thyrotropin receptor is a common requirement for activation by both mutations and its natural agonist.

A family with a novel TSH receptor activating germline mutation (p.Ala485Val).

A lack of thyroid hormones rather than excess thyrotropin causes abnormal skeletal development in hypothyroidism

A molecular dissection of the glycoprotein hormone receptors.

A mutation in the follicle-stimulating hormone receptor as a cause of familial spontaneous ovarian hyperstimulation syndrome.

A physiological role for the posttranslational cleavage of the thyrotropin receptor?

Activation of the cAMP pathway by the TSH receptor involves switching of the ectodomain from a tethered inverse agonist to an agonist

Allosteric modulation of binding properties between units of chemokine receptor homo- and hetero-oligomers.

Allosteric properties of G protein-coupled receptor oligomers

An activation switch in the rhodopsin family of G protein-coupled receptors: the thyrotropin receptor

Autosomal-dominant non-autoimmune hyperthyroidism presenting with neuromuscular symptoms

Characterization of a novel loss of function mutation of PAX8 in a familial case of congenital hypothyroidism with in-place, normal-sized thyroid

Choline head groups stabilize the matrix loop regions of the ATP/ADP carrier ScAAC2.

Deletion of the RNaseIII enzyme dicer in thyroid follicular cells causes hypothyroidism with signs of neoplastic alterations

Delineation of the discontinuous-conformational epitope of a monoclonal antibody displaying full in vitro and in vivo thyrotropin activity

Evidence for activity-regulated hormone-binding cooperativity across glycoprotein hormone receptor homomers

Functional zebrafish studies based on human genotyping point to netrin-1 as a link between aberrant cardiovascular development and thyroid dysgenesis

G protein-coupled receptors: mutations and endocrine diseases

GRIS: glycoprotein-hormone receptor information system

Generation of Functional Thyroid Tissue Using 3D-Based Culture of Embryonic Stem Cells

Generation of functional thyroid from embryonic stem cells

Genetic predictors of ovarian hyperstimulation syndrome in women undergoing in vitro fertilization

Germline mutations of TSH receptor gene as cause of nonautoimmune subclinical hypothyroidism.

Glycoprotein hormone receptors: determinants in leucine-rich repeats responsible for ligand specificity

Glycoprotein hormone receptors: link between receptor homodimerization and negative cooperativity

Identification and characterization of an endogenous chemotactic ligand specific for FPRL2

Identification of the first germline mutation in the extracellular domain of the follitropin receptor responsible for spontaneous ovarian hyperstimulation syndrome

Lethal respiratory failure and mild primary hypothyroidism in a term girl with a de novo heterozygous mutation in the TITF1/NKX2.1 gene

Lysine 183 and glutamic acid 157 of the TSH receptor: two interacting residues with a key role in determining specificity toward TSH and human CG.

Modulation of ligand selectivity associated with activation of the transmembrane region of the human follitropin receptor.

Monoclonal antibodies with thyroid stimulating activity, at last

New model systems to illuminate thyroid organogenesis. Part I: an update on the zebrafish toolbox

Novel inactivating follicle-stimulating hormone receptor mutations in a patient with premature ovarian insufficiency identified by next-generation sequencing gene panel analysis

Ovarian hyperstimulation syndrome due to a mutation in the follicle-stimulating hormone receptor.

Prediction of severity of symptoms in iatrogenic ovarian hyperstimulation syndrome by follicle-stimulating hormone receptor Ser680Asn polymorphism

Protein tyrosine-O-sulfation analysis by exhaustive product ion scanning with minimum collision offset in a NanoESI Q-TOF tandem mass spectrometer.

Single-cell transcriptome analysis reveals thyrocyte diversity in the zebrafish thyroid gland

Small amplified RNA-SAGE: an alternative approach to study transcriptome from limiting amount of mRNA

Specificity and promiscuity of gonadotropin receptors.

Structural differences in the hinge region of the glycoprotein hormone receptors: evidence from the sulfated tyrosine residues

TSH receptor function is required for normal thyroid differentiation in zebrafish

Transgenic zebrafish illuminate the dynamics of thyroid morphogenesis and its relationship to cardiovascular development

Understanding ovarian hyperstimulation syndrome