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List of works by Stefano Salvioli

A Cross-Sectional Analysis of Body Composition Among Healthy Elderly From the European NU-AGE Study: Sex and Country Specific Features

article

A Novel Approach to Improve the Estimation of a Diet Adherence Considering Seasonality and Short Term Variability - The NU-AGE Mediterranean Diet Experience

scientific article published on 05 March 2019

A meta-analysis on age-associated changes in blood DNA methylation: results from an original analysis pipeline for Infinium 450k data.

scientific article

A structural model of 20S immunoproteasomes: effect of LMP2 codon 60 polymorphism on expression, activity, intracellular localisation and insight into the regulatory mechanisms

scientific article published in April 2006

Accelerated bio-cognitive aging in Down syndrome: State of the art and possible deceleration strategies.

scientific article

Accelerated epigenetic aging in Down syndrome

scientific article

Age-Associated Loss of OPA1 in Muscle Impacts Muscle Mass, Metabolic Homeostasis, Systemic Inflammation, and Epithelial Senescence.

scientific article

Age-dependent changes in the susceptibility to apoptosis of peripheral blood CD4+ and CD8+ T lymphocytes with virgin or memory phenotype

scientific article published in April 2003

Age-dependent effects of in vitro radiofrequency exposure (mobile phone) on CD95+ T helper human lymphocytes

Age-related changes of adaptive and neuropsychological features in persons with Down Syndrome

scientific article

Both objective and paradoxical insomnia elicit a stress response involving mitokine production

scientific article published on 17 May 2020

Call for articles on neglected topics

scientific article published on 15 July 2019

Capturing Degeneracy in the Immune System

Centenarians as super-controls to assess the biological relevance of genetic risk factors for common age-related diseases: a proof of principle on type 2 diabetes

scientific article published on May 2013

Charting the NF-κB pathway interactome map

scientific article published in 2012

Circulating levels of adipokines and IGF-1 are associated with skeletal muscle strength of young and old healthy subjects

scientific article

Circulating mitochondrial DNA increases with age and is a familiar trait: Implications for “inflamm-aging”

scientific article published on 13 February 2014

Combating inflammaging through a Mediterranean whole diet approach: the NU-AGE project's conceptual framework and design

scientific article published on 14 December 2013

Complex patterns of gene expression in human T cells during in vivo aging

scientific article

Complexity of anti-immunosenescence strategies in humans

scientific article published on October 2006

Correction: Metabolic Signatures of Extreme Longevity in Northern Italian Centenarians Reveal a Complex Remodeling of Lipids, Amino Acids, and Gut Microbiota Metabolism.

scientific article published on 13 August 2013

Correction: X-chromosome-linked miR548am-5p is a key regulator of sex disparity in the susceptibility to mitochondria-mediated apoptosis

scientific article published on 04 November 2019

DNA Methylation Analysis of Ribosomal DNA in Adults With Down Syndrome

scientific article published on 27 April 2022

Different types of cell death in organismal aging and longevity: state of the art and possible systems biology approach

scientific article published on January 2008

Differential expression of perilipin 2 and 5 in human skeletal muscle during aging and their association with atrophy-related genes

scientific article published on 6 January 2015

Disease-specific plasma levels of mitokines FGF21, GDF15, and Humanin in type II diabetes and Alzheimer's disease in comparison with healthy aging

scientific article published on 31 October 2020

Down Syndrome, Ageing and Epigenetics

scientific article published on 01 January 2019

Erratum to: Differential expression of perilipin 2 and 5 in human skeletal muscle during aging and their association with atrophy-related genes

article

Erratum: A meta-analysis on age-associated changes in blood DNA methylation: results from an original analysis pipeline for Infinium 450k data ⬇️

scientific article

Evidence for sub-haplogroup h5 of mitochondrial DNA as a risk factor for late onset Alzheimer's disease

scientific article

GDF15 Plasma Level Is Inversely Associated With Level of Physical Activity and Correlates With Markers of Inflammation and Muscle Weakness

scientific article published on 12 May 2020

Gene expression of cytokines and cytokine receptors is modulated by the common variability of the mitochondrial DNA in cybrid cell lines.

scientific article published on August 2006

Genes involved in immune response/inflammation, IGF1/insulin pathway and response to oxidative stress play a major role in the genetics of human longevity: the lesson of centenarians

scientific article

Genes of human longevity: an endless quest?

scientific article

Genome-wide association meta-analysis of human longevity identifies a novel locus conferring survival beyond 90 years of age.

scientific article

Genomic stability, anti-inflammatory phenotype, and up-regulation of the RNAseH2 in cells from centenarians

scientific article published on 08 January 2019

Gut microbiome in Down syndrome

scientific article

Health relevance of the modification of low grade inflammation in ageing (inflammageing) and the role of nutrition

scientific article published on 9 September 2017

Hormone replacement therapy enhances IGF-1 signaling in skeletal muscle by diminishing miR-182 and miR-223 expressions: a study on postmenopausal monozygotic twin pairs

scientific article

Human aging and longevity are characterized by high levels of mitokines

scientific article published on 01 April 2019

Human longevity within an evolutionary perspective: the peculiar paradigm of a post-reproductive genetics

scientific article published on July 2007

Identification of a DNA methylation signature in blood cells from persons with Down Syndrome

scientific article

Identification of a T cell gene expression clock obtained by exploiting a MZ twin design

scientific article

Identification of single nucleotide polymorphisms in the p21 (CDKN1A) gene and correlations with longevity in the Italian population

scientific article

Immune system, cell senescence, aging and longevity--inflamm-aging reappraised

scientific article published on January 2013

Immunity, Inflammation and infections during aging

Immunobiography and the Heterogeneity of Immune Responses in the Elderly: A Focus on Inflammaging and Trained Immunity

scientific article

Immunoproteasome in cancer and neuropathologies: a new therapeutic target?

scientific article published on January 2013

In vitro IL-6 production by EBV-immortalized B lymphocytes from young and elderly people genotyped for -174 C/G polymorphism in IL-6 gene: a model to study the genetic basis of inflamm-aging

scientific article published on April 2003

In vitro exposure of human lymphocytes to 900 MHz CW and GSM modulated radiofrequency: studies of proliferation, apoptosis and mitochondrial membrane potential

scientific article published in August 2004

Increased Plin2 expression in human skeletal muscle is associated with sarcopenia and muscle weakness

scientific article

Inflammaging and 'Garb-aging'.

scientific article

Inflammaging and anti-inflammaging: a systemic perspective on aging and longevity emerged from studies in humans

scientific article published on 20 November 2006

Inflammaging and cancer: a challenge for the Mediterranean diet

scientific article published on 9 April 2015

Inflammaging, hormesis and the rationale for anti-aging strategies

scientific article published on 16 August 2020

Lamin A involvement in ageing processes

scientific article published on 21 May 2020

Lamins are rapamycin targets that impact human longevity: a study in centenarians

scientific article published on 23 October 2013

Lifelong calorie restriction affects indicators of colonic health in aging C57Bl/6J mice.

scientific article published on 20 March 2018

Lifelong maintenance of composition, function and cellular/subcellular distribution of proteasomes in human liver

scientific article

Mediterranean diet and inflammaging within the hormesis paradigm

scientific article published on 08 June 2017

Metabolic signatures of extreme longevity in northern Italian centenarians reveal a complex remodeling of lipids, amino acids, and gut microbiota metabolism

scientific article

Methylation of ELOVL2 gene as a new epigenetic marker of age

article

MicroRNAs linking inflamm-aging, cellular senescence and cancer

scientific article published on 17 May 2013

Mitochondria and mitochondria-induced signalling molecules as longevity determinants

scientific article published on 10 December 2016

Mitochondria hyperfusion and elevated autophagic activity are key mechanisms for cellular bioenergetic preservation in centenarians.

scientific article

Mitochondria, immunosenescence and inflammaging: a role for mitokines?

scientific article published on 05 August 2020

Mitochondrial DNA involvement in human longevity

scientific article published on 7 June 2006

Mitochondrial heterogeneity during staurosporine-induced apoptosis in HL60 cells: Analysis at the single cell and single organelle level

scientific article published in 2000

Molecular remodeling of potassium channels in fibroblasts from centenarians: a marker of longevity?

scientific article published on 19 September 2010

Muscle-specific Perilipin2 down-regulation affects lipid metabolism and induces myofiber hypertrophy

scientific article published on 04 October 2018

N-glycomic changes in serum proteins in type 2 diabetes mellitus correlate with complications and with metabolic syndrome parameters

scientific article

Oxidative stress and the ageing endocrine system ⬇️

scientific article published on February 26, 2013

Pathological Relevance of the Natural Immune System

Perilipin 2 and Age-Related Metabolic Diseases: A New Perspective

scientific article

Plasma N-Glycome Signature of Down Syndrome

scientific article published on 3 September 2015

Plasticity of lifelong calorie-restricted C57BL/6J mice in adapting to a medium-fat diet intervention at old age.

scientific article published on 21 December 2017

Propagation of a transmissible cytotoxic activity on cultures of human peripheral blood lymphocytes.

scientific article published in July 2008

Recovery from 6-month spaceflight at the International Space Station: muscle-related stress into a proinflammatory setting

scientific article published on 08 January 2019

Resistance to apoptosis of HCW-2 cells can be overcome by curcumin- or vincristine-induced mitotic catastrophe

scientific article published on October 2006

Ribosomal DNA instability: An evolutionary conserved fuel for inflammaging

scientific article published on 09 January 2020

Serum profiling of healthy aging identifies phospho- and sphingolipid species as markers of human longevity

scientific article published on January 2014

Sex disparity in cancer: roles of microRNAs and related functional players.

scientific article published on 19 January 2018

Sport and pelvic floor dysfunction in male and female athletes: A scoping review

scientific article published on 02 November 2020

Structural characterization of p53 isoforms due to the polymorphism at codon 72 by mass spectrometry and circular dichroism

scientific article

Supplementation of Enriched Polyunsaturated Fatty Acids and CLA Cheese on High Fat Diet: Effects on Lipid Metabolism and Fat Profile

scientific article published in 2022

Survival features of EBV-stabilized cells from centenarians: morpho-functional and transcriptomic analyses

scientific article

Systemic Age-Associated DNA Hypermethylation of ELOVL2 Gene: In Vivo and In Vitro Evidences of a Cell Replication Process

scientific article published on 26 September 2016

TP53 codon 72 polymorphism affects accumulation of mtDNA damage in human cells ⬇️

scientific article published on January 1, 2012

The Contextualized Genetics of Human Longevity: JACC Focus Seminar

scientific article published on 01 March 2020

The Continuum of Aging and Age-Related Diseases: Common Mechanisms but Different Rates

scientific article published on 12 March 2018

The Dual Role of the Pervasive “Fattish” Tissue Remodeling With Age

The New Antigenic Ecospace of the Globalized World and its Impact on the Immune System: The Battleground of Trade-off and Antagonistic Pleiotropy

The Pro/Pro genotype of the p53 codon 72 polymorphism modulates PAI-1 plasma levels in ageing.

scientific article

The adapter protein CD2AP binds to p53 protein in the cytoplasm and can discriminate its polymorphic variants P72R.

scientific article published on 26 September 2014

The emerging role of ECM crosslinking in T cell mobility as a hallmark of immunosenescence in humans

scientific article

The frequency of Klotho KL-VS polymorphism in a large Italian population, from young subjects to centenarians, suggests the presence of specific time windows for its effect

scientific article (publication date: February 2010)

The genetics of human longevity

scientific article published on May 2006

The impact of mitochondrial DNA on human lifespan: a view from studies on centenarians

scientific article published on June 2008

The nucleolar size is associated to the methylation status of ribosomal DNA in breast carcinomas

scientific article

The onset of type 2 diabetes: proposal for a multi-scale model.

scientific article published on 31 October 2013

The p53 codon 72 (Arg72Pro) polymorphism is associated with the degree of insulin resistance in type 2 diabetic subjects: a cross-sectional study

scientific article published on 27 December 2012

The smell of longevity: a combination of Volatile Organic Compounds (VOCs) can discriminate centenarians and their offspring from age-matched subjects and young controls

scientific article published on 05 December 2019

The three genetics (nuclear DNA, mitochondrial DNA, and gut microbiome) of longevity in humans considered as metaorganisms

scientific article

Traction Therapy for Cervical Radicular Syndrome is Statistically Significant but not Clinically Relevant for Pain Relief. A Systematic Literature Review with Meta-Analysis and Trial Sequential Analysis

scientific article published on 22 October 2020

Twelve-Week Daily Consumption of <i>ad hoc</i> Fortified Milk with ω-3, D, and Group B Vitamins Has a Positive Impact on Inflammaging Parameters: A Randomized Cross-Over Trial

scientific article published on 22 November 2020

What studies on human longevity tell us about the risk for cancer in the oldest old: data and hypotheses on the genetics and immunology of centenarians

scientific article

Why do centenarians escape or postpone cancer? The role of IGF-1, inflammation and p53.

scientific article published on 13 January 2009

X-chromosome-linked miR548am-5p is a key regulator of sex disparity in the susceptibility to mitochondria-mediated apoptosis

scientific article published on 11 September 2019

mtDNA mutations in human aging and longevity: controversies and new perspectives opened by high-throughput technologies

scientific article published on 05 April 2014

p53 codon 72 alleles influence the response to anticancer drugs in cells from aged people by regulating the cell cycle inhibitor p21WAF1.

scientific article published on 27 September 2005

p53 codon 72 genotype affects apoptosis by cytosine arabinoside in blood leukocytes

scientific article published in December 2002

p66(Shc) gene has a pro-apoptotic role in human cell lines and it is activated by a p53-independent pathway

scientific article published on 9 February 2006

tDCS and Robotics on Upper Limb Stroke Rehabilitation: Effect Modification by Stroke Duration and Type of Stroke

scientific article published on 31 March 2016

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