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List of works by Michael J Spinella

A p53-dominant transcriptional response to cisplatin in testicular germ cell tumor-derived human embryonal carcinoma.

scientific article

A phase 1 study of combined guadecitabine and cisplatin in platinum refractory germ cell cancer

scientific article published on 01 November 2020

Acute hypersensitivity of pluripotent testicular cancer-derived embryonal carcinoma to low-dose 5-aza deoxycytidine is associated with global DNA Damage-associated p53 activation, anti-pluripotency and DNA demethylation

scientific article

All-trans-retinoic acid antagonizes the Hedgehog pathway by inducing patched

scientific article published on 04 February 2014

Characterization and tissue-specific expression of human GSK-3-binding proteins FRAT1 and FRAT2

scientific article (publication date: 29 May 2002)

Developmentally-related candidate retinoic acid target genes regulated early during neuronal differentiation of human embryonal carcinoma

scientific article

Epigenetic Targeting of Platinum Resistant Testicular Cancer.

scientific article published on 22 December 2015

G0S2 Suppresses Oncogenic Transformation by Repressing a MYC-Regulated Transcriptional Program

scientific article published on 2 February 2016

G0S2 represses PI3K/mTOR signaling and increases sensitivity to PI3K/mTOR pathway inhibitors in breast cancer

scientific article

Headway and hurdles in the clinical development of dietary phytochemicals for cancer therapy and prevention: lessons learned from vitamin A derivatives

scientific article published on 16 January 2014

High DNA methyltransferase 3B expression mediates 5-aza-deoxycytidine hypersensitivity in testicular germ cell tumors

scientific article

Hypermethylation and global remodelling of DNA methylation is associated with acquired cisplatin resistance in testicular germ cell tumours

scientific article published on 30 October 2020

Incorporating DNA Methyltransferase Inhibitors (DNMTis) in the Treatment of Genitourinary Malignancies: A Systematic Review.

scientific article published on 11 December 2017

JSTOR

scholarly article published in 2007

JSTOR and the changing digital landscape

Limiting effects of RIP140 in estrogen signaling: potential mediation of anti-estrogenic effects of retinoic acid.

scientific article

Modulation of clock gene expression by the transcriptional coregulator receptor interacting protein 140 (RIP140)

scientific article

Negative feedback at the level of nuclear receptor coregulation. Self-limitation of retinoid signaling by RIP140.

scientific article published on 22 September 2003

Nestin is expressed in the basal/myoepithelial layer of the mammary gland and is a selective marker of basal epithelial breast tumors

scientific article published on January 2007

Reciprocal epigenetic remodeling controls testicular cancer hypersensitivity to hypomethylating agents and chemotherapy

scientific article published on 15 September 2021

Refractory testicular germ cell tumors are highly sensitive to the second generation DNA methylation inhibitor guadecitabine

scientific article

Repression of cyclin D1 as a target for germ cell tumors.

scientific article published on February 2007

Retinoic acid mediates long-paced oscillations in retinoid receptor activity: evidence for a potential role for RIP140.

scientific article

Retinoic acid represses a cassette of candidate pluripotency chromosome 12p genes during induced loss of human embryonal carcinoma tumorigenicity

scientific article

Retinoid target gene activation during induced tumor cell differentiation: human embryonal carcinoma as a model

scientific article

Retinoids in cancer therapy and chemoprevention: promise meets resistance ⬇️

scientific article published on October 20, 2003

Selective repression of retinoic acid target genes by RIP140 during induced tumor cell differentiation of pluripotent human embryonal carcinoma cells

scientific article

Serine/threonine kinase 17A is a novel candidate for therapeutic targeting in glioblastoma

scientific article

Serine/threonine kinase 17A is a novel p53 target gene and modulator of cisplatin toxicity and reactive oxygen species in testicular cancer cells

scientific article

Testicular Germ Cell Tumors: A Paradigm for the Successful Treatment of Solid Tumor Stem Cells

scientific article published on August 2006

The direct p53 target gene, FLJ11259/DRAM, is a member of a novel family of transmembrane proteins

scientific article published on 22 February 2007

Wnt pathway reprogramming during human embryonal carcinoma differentiation and potential for therapeutic targeting

scientific article

p53 in human embryonal carcinoma: identification of a transferable, transcriptional repression domain in the N-terminal region of p53.

scientific article

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