Search filters

List of works by Jun-Ichi Abe

A crucial role for p90RSK-mediated reduction of ERK5 transcriptional activity in endothelial dysfunction and atherosclerosis

scientific article

A positive feedback loop of phosphodiesterase 3 (PDE3) and inducible cAMP early repressor (ICER) leads to cardiomyocyte apoptosis.

scientific article

Adaptation and Changes in Actin Dynamics and Cell Motility as Early Responses of Cultured Mammalian Cells to Altered Gravitational Vector

scientific article published on 30 May 2022

Axl modulates immune activation of smooth muscle cells in vein graft remodeling

scientific article

Bcr kinase activation by angiotensin II inhibits peroxisome-proliferator-activated receptor gamma transcriptional activity in vascular smooth muscle cells

scientific article

Ca2+/calmodulin‐stimulated PDE1 regulates the beta‐catenin/TCF signaling through PP2A B56 gamma subunit in proliferating vascular smooth muscle cells ⬇️

scientific article published on November 16, 2010

Cardiac Nuclear High-Mobility Group Box 1 Ameliorates Pathological Cardiac Hypertrophy by Inhibiting DNA Damage Response

article

Cardio-Oncology: Learning From the Old, Applying to the New

scientific article published on 25 November 2020

Cardiovascular Inflammation 2012: Reactive Oxygen Species, SUMOylation, and Biomarkers in Cardiovascular Inflammation

scientific article published on 10 March 2013

Central role of endogenous Toll-like receptor-2 activation in regulating inflammation, reactive oxygen species production, and subsequent neointimal formation after vascular injury

scientific article published on 16 May 2006

Comparison of Chain-Length Preferences and Glucan Specificities of Isoamylase-Type α-Glucan Debranching Enzymes from Rice, Cyanobacteria, and Bacteria

scientific article

Coordination of Cellular Localization-Dependent Effects of Sumoylation in Regulating Cardiovascular and Neurological Diseases

scientific article published on January 2017

Coronary Artery Dose-Volume Parameters Predict Risk of Calcification After Radiation Therapy

scientific article published on 01 October 2019

Critical Role of Cytosolic DNA and Its Sensing Adaptor STING in Aortic Degeneration, Dissection, and Rupture

scientific article published on 30 December 2019

Developing a Reliable Mouse Model for Cancer Therapy-Induced Cardiovascular Toxicity in Cancer Patients and Survivors.

scientific article

Diagnosis, grading, and treatment recommendations for children, adolescents, and young adults with sinusoidal obstructive syndrome: an international expert position statement

scientific article published on 07 December 2019

Differential Role of MEK5α and MEK5β in BMK1/ERK5 Activation ⬇️

scientific article (publication date: 9 January 2004)

Disturbed Flow-Induced Endothelial Proatherogenic Signaling Via Regulating Post-Translational Modifications and Epigenetic Events

scientific article published on 30 December 2015

Does simile comprehension differ from metaphor comprehension? A functional MRI study ⬇️

scientific article published on April 24, 2012

Editorial: Cardio-Oncology: From Bench to Bedside

Effects of MEK5/ERK5 association on small ubiquitin-related modification of ERK5: implications for diabetic ventricular dysfunction after myocardial infarction

scientific article published on 08 May 2008

En Face Preparation of Mouse Blood Vessels

scientific article published on 19 May 2017

Endothelial senescence is induced by phosphorylation and nuclear export of telomeric repeat binding factor 2-interacting protein.

scientific article published on 2 May 2019

Endothelial senescence-associated secretory phenotype (SASP) is regulated by Makorin-1 ubiquitin E3 ligase

scientific article published on 30 August 2019

Endothelial-to-Osteoblast Conversion Generates Osteoblastic Metastasis of Prostate Cancer

scientific article published in June 2017

Enigma of Inflammasome Activation by Kinases

scientific article published on 24 July 2019

Flow shear stress and atherosclerosis: a matter of site specificity

scientific article published on 08 April 2011

Flow signaling and atherosclerosis

scientific article published on 30 December 2016

Fluid shear stress inhibits TNF-mediated JNK activation via MEK5-BMK1 in endothelial cells

scientific article

Functional role of phosphodiesterase 3 in cardiomyocyte apoptosis: implication in heart failure

scientific journal article

Growth Factor Midkine Aggravates Pulmonary Arterial Hypertension via Surface Nucleolin

scientific article published on 25 June 2020

Incidence and Onset of Severe Cardiac Events After Radiotherapy for Esophageal Cancer

scientific article published on 26 June 2020

Insulin activates RSK (p90 ribosomal S6 kinase) to trigger a new negative feedback loop that regulates insulin signaling for glucose metabolism.

scientific article published on 13 September 2013

Insulin-like growth factor-1 enhances inflammatory responses in endothelial cells: role of Gab1 and MEKK3 in TNF-alpha-induced c-Jun and NF-kappaB activation and adhesion molecule expression

scientific article

Ionizing Radiation Induces Endothelial Inflammation and Apoptosis via p90RSK-Mediated ERK5 S496 Phosphorylation.

scientific article

Kinase-SUMO networks in diabetes-mediated cardiovascular disease

scientific article published on 16 January 2016

MAGI1 as a link between endothelial activation and ER stress drives atherosclerosis

scientific article published on 04 April 2019

MicroRNA 199a and the eNOS (Endothelial NO Synthase)/NO Pathway

scientific article published on 01 October 2018

Mitochondria and chronic effects of cancer therapeutics: The clinical implications

scientific article published on 20 October 2020

Mitochondrial Dok-4 recruits Src kinase and regulates NF-kappaB activation in endothelial cells.

scientific article published on 26 April 2005

Modern Radiotherapy and Risk of Cardiotoxicity

scientific article published on 13 October 2020

Molecular characterization of atherosclerosis in HIV positive persons

scientific article published on 05 February 2021

Multiple Functions of Protein Inhibitor of Activated STAT1 in Regulating Endothelial Cell Proliferation and Inflammation

scientific article published on September 2016

Neural mechanisms involved in the comprehension of metaphoric and literal sentences: an fMRI study

scientific article published on 06 July 2007

Perlecan Proteolysis Induces an α2β1 Integrin- and Src Family Kinase-dependent Anti-apoptotic Pathway in Fibroblasts in the Absence of Focal Adhesion Kinase Activation

scientific article published in Journal of Biological Chemistry

Platelet Extracellular Regulated Protein Kinase 5 Is a Redox Switch and Triggers Maladaptive Platelet Responses and Myocardial Infarct Expansion

scientific article

Pyroptosis as a Regulated Form of Necrosis: PI+/Annexin V-/High Caspase 1/Low Caspase 9 Activity in Cells = Pyroptosis?

scientific article published on May 2016

Radiation-Induced Cardiovascular Disease: Mechanisms and Importance of Linear Energy Transfer

scientific article published on 31 January 2018

Radiation-Induced Endothelial Vascular Injury: A Review of Possible Mechanisms

article by Bhanu Prasad Venkatesulu et al published August 2018 in JACC. Basic to translational science

Rapid Evaluation of CRISPR Guides and Donors for Engineering Mice

scientific article published on 08 June 2020

Reactive Oxygen Species, SUMOylation, and Endothelial Inflammation

scientific article

Regulation of Kir2.1 Function Under Shear Stress and Cholesterol Loading.

scientific article

Regulation of epidermal growth factor-induced connexin 43 gap junction communication by big mitogen-activated protein kinase1/ERK5 but not ERK1/2 kinase activation

scientific article

Role of PKCs and NF-kappaB activation in myocardial inflammation: enemy or ally?

scientific article published on 14 July 2007

STING-IRF3 Triggers Endothelial Inflammation in Response to Free Fatty Acid-Induced Mitochondrial Damage in Diet-Induced Obesity

scientific article published on 16 March 2017

SUMO--a post-translational modification with therapeutic potential?

scientific article

Senescent Phenotype Induced by p90RSK-NRF2 Signaling Sensitizes Monocytes and Macrophages to Oxidative Stress in HIV-Positive Individuals

scientific article published on 01 February 2019

Speckle-Tracking Echocardiography in Cardio-Oncology and Beyond

scientific article published on 01 April 2020

Stress and vascular responses: atheroprotective effect of laminar fluid shear stress in endothelial cells: possible role of mitogen-activated protein kinases

scientific article

Sub-cellular localization specific SUMOylation in the heart

scientific article published on 24 January 2017

TR4 nuclear receptor functions as a fatty acid sensor to modulate CD36 expression and foam cell formation.

scientific article published on 28 July 2009

The Future of Onco-Cardiology: We Are Not Just "Side Effect Hunters".

scientific article published on September 2016

The Ser/Thr kinase p90RSK promotes kidney fibrosis by modulating fibroblast-epithelial crosstalk

scientific article published on 10 May 2019

The acquisition process of musical tonal schema: implications from connectionist modeling.

scientific article

The novel role of the C-terminal region of SHP-2. Involvement of Gab1 and SHP-2 phosphatase activity in Elk-1 activation

scientific article

Time-dependent replicative senescence vs. disturbed flow-induced pre-mature aging in atherosclerosis

scientific article published on 24 June 2020

Topoisomerase 2B Decrease Results in Diastolic Dysfunction <i>via</i> p53 and Akt: A Novel Pathway

scientific article published on 06 November 2020

Vinpocetine inhibits NF-kappaB-dependent inflammation via an IKK-dependent but PDE-independent mechanism

scientific article

p90 ribosomal S6 kinase regulates activity of the renin-angiotensin system: a pathogenic mechanism for ischemia-reperfusion injury

scientific article

p90RSK-MAGI1 Module Controls Endothelial Permeability by Post-translational Modifications of MAGI1 and Hippo Pathway

scientific article published on 13 November 2020

Paulina is supported by:

About Paulina

Help