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List of works by Gerald W Dorn II

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Loss of cyclophilin D reveals a critical role for mitochondrial permeability transition in cell death

scientific article (publication date: 31 March 2005)
PINK1-phosphorylated mitofusin 2 is a Parkin receptor for culling damaged mitochondria

scientific journal article
Nix is critical to two distinct phases of mitophagy, reactive oxygen species-mediated autophagy induction and Parkin-ubiquitin-p62-mediated mitochondrial priming

scientific article
Genetic manipulation of periostin expression reveals a role in cardiac hypertrophy and ventricular remodeling

scientific article published on 14 June 2007
MicroRNA-133a protects against myocardial fibrosis and modulates electrical repolarization without affecting hypertrophy in pressure-overloaded adult hearts

scientific article
Mitochondrial oxidative stress mediates angiotensin II-induced cardiac hypertrophy and Galphaq overexpression-induced heart failure

scientific article published on 10 February 2011
miR-15 Family Regulates Postnatal Mitotic Arrest of Cardiomyocytes

scientific article published on July 21, 2011
Human phospholamban null results in lethal dilated cardiomyopathy revealing a critical difference between mouse and human

scientific article
Mitochondrial Fusion is Essential for Organelle Function and Cardiac Homeostasis

scientific article published on November 3, 2011
Reciprocal regulation of myocardial microRNAs and messenger RNA in human cardiomyopathy and reversal of the microRNA signature by biomechanical support.

scientific article published on 23 February 2009
Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci

scientific article
β1-adrenergic receptor polymorphisms confer differential function and predisposition to heart failure

scientific article published on September 14, 2003
A GRK5 polymorphism that inhibits beta-adrenergic receptor signaling is protective in heart failure

scientific article published on 20 April 2008
A mutation in the human phospholamban gene, deleting arginine 14, results in lethal, hereditary cardiomyopathy.

scientific article
Inhibition of ischemic cardiomyocyte apoptosis through targeted ablation of Bnip3 restrains postinfarction remodeling in mice

scientific article
Bax regulates primary necrosis through mitochondrial dynamics

scientific journal article
An FHL1-containing complex within the cardiomyocyte sarcomere mediates hypertrophic biomechanical stress responses in mice

scientific article published on 3 November 2008
G protein-coupled receptor kinase 2 ablation in cardiac myocytes before or after myocardial infarction prevents heart failure

scientific article
Mitochondrial death protein Nix is induced in cardiac hypertrophy and triggers apoptotic cardiomyopathy

scientific article
Phenotyping hypertrophy: eschew obfuscation

scientific article published on 01 June 2003
Additive protection of the ischemic heart ex vivo by combined treatment with delta-protein kinase C inhibitor and epsilon-protein kinase C activator

scientific article
Cardiac-specific ablation of G-protein receptor kinase 2 redefines its roles in heart development and beta-adrenergic signaling

scientific article published on 28 September 2006
Inhibition of cardiac myocyte apoptosis improves cardiac function and abolishes mortality in the peripartum cardiomyopathy of Galpha(q) transgenic mice

scientific article published on 24 November 2003
Parkin-mediated mitophagy directs perinatal cardiac metabolic maturation in mice

scientific article published on 3 December 2015
G protein-coupled receptor kinase 2 activity impairs cardiac glucose uptake and promotes insulin resistance after myocardial ischemia.

scientific article
Dual autonomous mitochondrial cell death pathways are activated by Nix/BNip3L and induce cardiomyopathy

scientific article
Pharmacological- and gene therapy-based inhibition of protein kinase Calpha/beta enhances cardiac contractility and attenuates heart failure

scientific article published on 31 July 2006
How Mitochondrial Dynamism Orchestrates Mitophagy

scientific article published on May 22, 2015
Nix-mediated apoptosis links myocardial fibrosis, cardiac remodeling, and hypertrophy decompensation

scientific article published on 4 January 2008
Super-Suppression of Mitochondrial Reactive Oxygen Species Signaling Impairs Compensatory Autophagy in Primary Mitophagic Cardiomyopathy

scientific article published on May 29, 2014
Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height

scientific article
microRNAs in heart disease: putative novel therapeutic targets?

scientific article
Common variants in HSPB7 and FRMD4B associated with advanced heart failure

scientific article
Endoplasmic reticulum-mitochondria crosstalk in NIX-mediated murine cell death

scientific article published on 08 December 2008
Distinct pathways regulate proapoptotic Nix and BNip3 in cardiac stress

scientific article published on 16 November 2005
Unrestrained erythroblast development in Nix-/- mice reveals a mechanism for apoptotic modulation of erythropoiesis

scholarly article
Epigenetic coordination of embryonic heart transcription by dynamically regulated long noncoding RNAs

scientific article
Mitochondrial Function, Biology, and Role in Disease: A Scientific Statement From the American Heart Association.

scientific article published on 28 April 2016
Intracellular transport mechanisms of signal transducers

scientific article
ERRATUM: Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height

article by Matthew B. Lanktree et al published June 2012 in American Journal of Human Genetics
Direct and Indirect Involvement of MicroRNA-499 in Clinical and Experimental Cardiomyopathy

scientific article published on June 29, 2012
Cardiomyocyte degeneration with calpain deficiency reveals a critical role in protein homeostasis

scientific article
Cardiac miR-133a overexpression prevents early cardiac fibrosis in diabetes

scientific article
RISC RNA Sequencing for Context-Specific Identification of In Vivo MicroRNA Targets

scientific article published on October 28, 2010
Protein Kinase Cα Negatively Regulates Systolic and Diastolic Function in Pathological Hypertrophy

scientific article published on November 6, 2003
Interdependence of Parkin-Mediated Mitophagy and Mitochondrial Fission in Adult Mouse Hearts

scientific article published on 2 June 2015
Mediating ERK 1/2 signaling rescues congenital heart defects in a mouse model of Noonan syndrome

scientific article published in August 2007
Correcting mitochondrial fusion by manipulating mitofusin conformations

scientific article
Clinical and genetic modifiers of long-term survival in heart failure

scientific article published on July 2009
Inhibition of apoptosis-regulated signaling kinase-1 and prevention of congestive heart failure by estrogen

scientific article published on 11 June 2007

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