List of works - Marie Kosco-Vilbois

3D and 4D imaging of immune cells in vitro and in vivo

scientific article published on 15 October 2008

A homogeneous 384-well high-throughput binding assay for a TNF receptor using alphascreen technology

scientific article published in October 2003

A novel Toll-like receptor 4 antagonist antibody ameliorates inflammation but impairs mucosal healing in murine colitis

scientific article published on 09 April 2009

A specific anti-citrullinated protein antibody profile identifies a group of rheumatoid arthritis patients with a toll-like receptor 4-mediated disease

scientific article published on 6 October 2016

Antibody Neutralization of CXCL10 in Vivo Is Dependent on Binding to Free and Not Endothelial-bound Chemokine: IMPLICATIONS FOR THE DESIGN OF A NEW GENERATION OF ANTI-CHEMOKINE THERAPEUTIC ANTIBODIES.

scientific article published on 30 January 2017

CC chemokine CCL5 plays a central role impacting infarct size and post-infarction heart failure in mice

scientific article published on 23 May 2011

Characterization of a surrogate murine antibody to model anti-human CD3 therapies

scientific article published on 18 April 2013

Chemokines derived from soluble fusion proteins expressed in Escherichia coli are biologically active

scientific article published on August 2005

Co-engaging CD47 and CD19 with a bispecific antibody abrogates B-cell receptor/CD19 association leading to impaired B-cell proliferation

scientific article published on 31 January 2019

Combination therapies in the context of anti-CD3 antibodies for the treatment of autoimmune diseases

scientific article

Comparing CDRH3 diversity captured from secondary lymphoid organs for the generation of recombinant human antibodies

scientific article

Constitutive activation of epithelial TLR4 augments inflammatory responses to mucosal injury and drives colitis-associated tumorigenesis

scientific article

De novo isolation of antibodies with pH-dependent binding properties

Deep sequencing of phage display libraries to support antibody discovery

scientific article

Deriving a germinal center lymphocyte migration model from two-photon data

scientific article

Dual display: phage selection driven by co-engagement of two targets by two different antibody fragments

scientific article

Effect of Toll-like receptor 4 blockade on pulmonary inflammation caused by mechanical ventilation and bacterial endotoxin

scientific article published in June 2008

Enhancement of islet engraftment and achievement of long-term islet allograft survival by Toll-like receptor 4 blockade.

scientific article published in January 2015

Epitope-dependent inhibition of T cell activation by the Ea transgene: an explanation for transgene-mediated protection from murine lupus

scientific article published on 01 August 2004

Exploiting light chains for the scalable generation and platform purification of native human bispecific IgG.

scientific article

Germinal center B cells govern their own fate via antibody feedback

scientific article published on 18 February 2013

IL-17F co-expression improves cell growth characteristics and enhances recombinant protein production during CHO cell line engineering

scientific article

Inhibition of airway inflammation by amino-terminally modified RANTES/CC chemokine ligand 5 analogues is not mediated through CCR3.

scientific article published on November 2003

Interferon gamma (IFNg) production is associated to disease parameters in TLR9-induced secondary hemophagocytic lymphohistiocytosis (sHLH) in mice.

scientific article published on 17 September 2014

Long‐term amelioration of established collagen‐induced arthritis achieved with short‐term therapy combining anti‐CD3 and anti–tumor necrosis factor treatments ⬇️

scientific article published on 01 October 2012

Maximizing the potency of an anti-TLR4 monoclonal antibody by exploiting proximity to Fcγ receptors

scientific article

Neutralization of IFNgamma defeats haemophagocytosis in LCMV-infected perforin- and Rab27a-deficient mice

scientific article

Novel Insights into Interleukin 6 (IL-6) Cis- and Trans-signaling Pathways by Differentially Manipulating the Assembly of the IL-6 Signaling Complex

scientific article

Osteopontin is upregulated during in vivo demyelination and remyelination and enhances myelin formation in vitro

scientific article published in April 2004

Pivotal involvement of Fcgamma receptor IIA in the neutralization of lipopolysaccharide signaling via a potent novel anti-TLR4 monoclonal antibody 15C1.

scientific article

Rapid, simple and high yield production of recombinant proteins in mammalian cells using a versatile episomal system.

scientific article published on 24 April 2010

Robust Antibody-Antigen Complexes Prediction Generated by Combining Sequence Analyses, Mutagenesis, In Vitro Evolution, X-ray Crystallography and In Silico Docking

scientific article

Robust recombinant FcRn production in mammalian cells enabling oriented immobilization for IgG binding studies

scientific article published on 12 September 2011

Selective Blockade of the Ubiquitous Checkpoint Receptor CD47 Is Enabled by Dual-Targeting Bispecific Antibodies.

scientific article published on February 2017

Selective antibody intervention of Toll-like receptor 4 activation through Fc γ receptor tethering

scientific article

Short-term treatment with anti-CD3 antibody reduces the development and progression of atherosclerosis in mice

scientific article published on 16 October 2006

Spatiotemporal expression of endogenous TLR4 ligands leads to inflammation and bone erosion in mouse collagen-induced arthritis

scientific article

TLR4/MD-2 monoclonal antibody therapy affords protection in experimental models of septic shock

scientific article published on November 2007

The 16th International Conference on Lymphatic Tissues and Germinal Centers in Immune Responses

scientific article published on 01 September 2009

Therapeutic Effects of Treatment with Anti-TLR2 and Anti-TLR4 Monoclonal Antibodies in Polymicrobial Sepsis

scientific article published on 6 July 2015

Transferring the Characteristics of Naturally Occurring and Biased Antibody Repertoires to Human Antibody Libraries by Trapping CDRH3 Sequences ⬇️

scientific article published on August 24, 2012

List of works by Marie Kosco-Vilbois

3D and 4D imaging of immune cells in vitro and in vivo

A homogeneous 384-well high-throughput binding assay for a TNF receptor using alphascreen technology

A novel Toll-like receptor 4 antagonist antibody ameliorates inflammation but impairs mucosal healing in murine colitis

A specific anti-citrullinated protein antibody profile identifies a group of rheumatoid arthritis patients with a toll-like receptor 4-mediated disease

Antibody Neutralization of CXCL10 in Vivo Is Dependent on Binding to Free and Not Endothelial-bound Chemokine: IMPLICATIONS FOR THE DESIGN OF A NEW GENERATION OF ANTI-CHEMOKINE THERAPEUTIC ANTIBODIES.

CC chemokine CCL5 plays a central role impacting infarct size and post-infarction heart failure in mice

Characterization of a surrogate murine antibody to model anti-human CD3 therapies

Chemokines derived from soluble fusion proteins expressed in Escherichia coli are biologically active

Co-engaging CD47 and CD19 with a bispecific antibody abrogates B-cell receptor/CD19 association leading to impaired B-cell proliferation

Combination therapies in the context of anti-CD3 antibodies for the treatment of autoimmune diseases

Comparing CDRH3 diversity captured from secondary lymphoid organs for the generation of recombinant human antibodies

Constitutive activation of epithelial TLR4 augments inflammatory responses to mucosal injury and drives colitis-associated tumorigenesis

De novo isolation of antibodies with pH-dependent binding properties

Deep sequencing of phage display libraries to support antibody discovery

Deriving a germinal center lymphocyte migration model from two-photon data

Dual display: phage selection driven by co-engagement of two targets by two different antibody fragments

Effect of Toll-like receptor 4 blockade on pulmonary inflammation caused by mechanical ventilation and bacterial endotoxin

Enhancement of islet engraftment and achievement of long-term islet allograft survival by Toll-like receptor 4 blockade.

Epitope-dependent inhibition of T cell activation by the Ea transgene: an explanation for transgene-mediated protection from murine lupus

Exploiting light chains for the scalable generation and platform purification of native human bispecific IgG.

Germinal center B cells govern their own fate via antibody feedback

IL-17F co-expression improves cell growth characteristics and enhances recombinant protein production during CHO cell line engineering

Inhibition of airway inflammation by amino-terminally modified RANTES/CC chemokine ligand 5 analogues is not mediated through CCR3.

Interferon gamma (IFNg) production is associated to disease parameters in TLR9-induced secondary hemophagocytic lymphohistiocytosis (sHLH) in mice.

Long‐term amelioration of established collagen‐induced arthritis achieved with short‐term therapy combining anti‐CD3 and anti–tumor necrosis factor treatments ⬇️

Maximizing the potency of an anti-TLR4 monoclonal antibody by exploiting proximity to Fcγ receptors

Neutralization of IFNgamma defeats haemophagocytosis in LCMV-infected perforin- and Rab27a-deficient mice

Novel Insights into Interleukin 6 (IL-6) Cis- and Trans-signaling Pathways by Differentially Manipulating the Assembly of the IL-6 Signaling Complex

Osteopontin is upregulated during in vivo demyelination and remyelination and enhances myelin formation in vitro

Pivotal involvement of Fcgamma receptor IIA in the neutralization of lipopolysaccharide signaling via a potent novel anti-TLR4 monoclonal antibody 15C1.

Rapid, simple and high yield production of recombinant proteins in mammalian cells using a versatile episomal system.

Robust Antibody-Antigen Complexes Prediction Generated by Combining Sequence Analyses, Mutagenesis, In Vitro Evolution, X-ray Crystallography and In Silico Docking

Robust recombinant FcRn production in mammalian cells enabling oriented immobilization for IgG binding studies

Selective Blockade of the Ubiquitous Checkpoint Receptor CD47 Is Enabled by Dual-Targeting Bispecific Antibodies.

Selective antibody intervention of Toll-like receptor 4 activation through Fc γ receptor tethering

Short-term treatment with anti-CD3 antibody reduces the development and progression of atherosclerosis in mice

Spatiotemporal expression of endogenous TLR4 ligands leads to inflammation and bone erosion in mouse collagen-induced arthritis

TLR4/MD-2 monoclonal antibody therapy affords protection in experimental models of septic shock

The 16th International Conference on Lymphatic Tissues and Germinal Centers in Immune Responses

Therapeutic Effects of Treatment with Anti-TLR2 and Anti-TLR4 Monoclonal Antibodies in Polymicrobial Sepsis

Transferring the Characteristics of Naturally Occurring and Biased Antibody Repertoires to Human Antibody Libraries by Trapping CDRH3 Sequences ⬇️