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List of works by Debbie van Baarle

A comparative study of HLA binding affinity and ligand diversity: implications for generating immunodominant CD8+ T cell responses

scientific article published in February 2009

A lower viral set point but little immunological impact after early treatment during primary HIV infection

scientific article

A nonprogressive clinical course in HIV-infected individuals expressing human leukocyte antigen B57/5801 is associated with preserved CD8+ T lymphocyte responsiveness to the HW9 epitope in Nef

scientific article published on 01 March 2008

Absolute level of Epstein-Barr virus DNA in human immunodeficiency virus type 1 infection is not predictive of AIDS-related non-Hodgkin lymphoma

scientific article published on 17 July 2002

Abundance of early functional HIV-specific CD8+ T cells does not predict AIDS-free survival time

scientific article

Activation of extrinsic apoptosis pathway in HCV monoinfected and HIV-HCV coinfected patients, irrespective of liver disease severity

scientific article published on July 2014

Altered EBV viral load setpoint after HIV seroconversion is in accordance with lack of predictive value of EBV load for the occurrence of AIDS-related non-Hodgkin lymphoma

scientific article published in June 2004

An unanticipated lack of consensus cytotoxic T lymphocyte epitopes in HIV-1 databases: the contribution of prediction programs

scientific article published in January 2008

Analysis of immune responses against a wide range of Mycobacterium tuberculosis antigens in patients with active pulmonary tuberculosis

scientific article published on 26 September 2012

Analysis of the effect of highly active antiretroviral therapy during acute HIV-1 infection on HIV-specific CD4 T cell functions

scientific article published on 01 July 2005

Association between IL28B polymorphisms and first-phase viral load decrease in chronic hepatitis C virus-infected patients treated with peginterferon alfa-2b/ribavirin ⬇️

scientific article published on October 4, 2011

Author Correction: Impact of delivery mode-associated gut microbiota dynamics on health in the first year of life

scientific article published on 25 November 2019

CD4/CD8 ratio is a promising candidate for non-invasive measurement of liver fibrosis in chronic HCV-monoinfected patients

scientific article published on 22 January 2014

CD8+ TCR Repertoire Formation Is Guided Primarily by the Peptide Component of the Antigenic Complex

scientific article published on 24 December 2012

CMV immune evasion and manipulation of the immune system with aging

scientific article

CTL escape and increased viremia irrespective of HIV-specific CD4+ T-helper responses in two HIV-infected individuals

article

Characterization of virus-specific CD8(+) effector T cells in the course of HIV-1 infection: longitudinal analyses in slow and rapid progressors

scientific article

Chromosomally integrated human herpesvirus 6: transmission via cord blood-derived unrelated hematopoietic stem cell transplantation

scientific article published on 8 July 2009

Complementarity of Binding Motifs is a General Property of HLA-A and HLA-B Molecules and Does Not Seem to Effect HLA Haplotype Composition.

scientific article

Complementary role of HCV and HIV in T-cell activation and exhaustion in HIV/HCV coinfection

scientific article

Complex T-cell receptor repertoire dynamics underlie the CD8+ T-cell response to HIV-1

scientific article published on 15 October 2014

Comprehensive Analysis of the Naturally Processed Peptide Repertoire: Differences between HLA-A and B in the Immunopeptidome

scientific article

Correlates of resistance to HIV-1 infection in homosexual men with high-risk sexual behaviour

scientific article published in May 2004

Cytomegalovirus persistence and T-cell immunosenescence in people aged fifty and older: A systematic review

scientific article published on 13 February 2016

Cytomegalovirus rather than HIV triggers the outgrowth of effector CD8+CD45RA+CD27- T cells in HIV-1-infected children

scientific article published on 01 July 2005

Detailed kinetics of EBV-specific CD4+ and CD8+ T cells during primary EBV infection in a kidney transplant patient

scientific article published on 4 January 2006

Differences in T-cell infiltrates and survival between HPV+ and HPV- oropharyngeal squamous cell carcinoma

scientific article published on 07 January 2016

Differential characteristics of cytotoxic T lymphocytes restricted by the protective HLA alleles B*27 and B*57 in HIV-1 infection

scientific article published on November 2014

Differential usage of cellular niches by cytomegalovirus versus EBV- and influenza virus-specific CD8+ T cells

scientific article published in October 2006

Direct ex vivo detection of HLA-DR3-restricted cytomegalovirus- and Mycobacterium tuberculosis-specific CD4+ T cells

scientific article published on 16 August 2005

Discriminative expression of whole blood genes in HIV patients with latent and active TB in Ethiopia

scientific article published on 13 June 2016

Disruption of circadian rhythm by alternating light-dark cycles aggravates atherosclerosis development in APOE*3-Leiden.CETP mice

scientific article published on 10 October 2019

Distribution of immune cells in the human cervix and implications for HIV transmission

scientific article published on 10 January 2014

Dynamics of cytomegalovirus (CMV)-specific T cells in HIV-1-infected individuals progressing to AIDS with CMV end-organ disease

scientific article

Early measles vaccination during an outbreak in The Netherlands: reduced short and long-term antibody responses in children vaccinated before 12 months of age

article

Editorial: Role of HLA and KIR in Viral Infections.

scientific article published on 27 July 2016

Elevated granzyme M-expressing lymphocytes during cytomegalovirus latency and reactivation after allogeneic stem cell transplantation

scientific article published on 18 November 2013

Emergence of monoclonal antibody b12-resistant human immunodeficiency virus type 1 variants during natural infection in the absence of humoral or cellular immune pressure

scientific article

Enhancement of human papilloma virus type 16 E7 specific T cell responses by local invasive procedures in patients with (pre)malignant cervical neoplasia

scientific article

Epstein-Barr virus infects B and non-B lymphocytes in HIV-1-infected children and adolescents.

scientific article published on 25 September 2006

Expression of chemokine receptors CCR5 and CXCR4 on CD4+ T cells and plasma chemokine levels during treatment of active tuberculosis in HIV-1-coinfected patients

scientific article published in July 2005

Failing immune control as a result of impaired CD8+ T-cell maturation: CD27 might provide a clue

scientific article (publication date: December 2002)

Fcγ receptor antigen targeting potentiates cross-presentation by human blood and lymphoid tissue BDCA-3+ dendritic cells

scientific article published on 23 October 2012

Female sex and IL28B, a synergism for spontaneous viral clearance in hepatitis C virus (HCV) seroconverters from a community-based cohort

scientific article

Functional restoration of human immunodeficiency virus and Epstein-Barr virus-specific CD8(+) T cells during highly active antiretroviral therapy is associated with an increase in CD4(+) T cells

scientific article published in April 2002

Gene expression profiles classifying clinical stages of tuberculosis and monitoring treatment responses in Ethiopian HIV-negative and HIV-positive cohorts

scientific article published on 10 December 2019

Guiding the action of the immune system: Interactions between the immune system and non-immune tissues

scientific article published on 17 February 2011

HCV monoinfection and HIV/HCV coinfection enhance T-cell immune senescence in injecting drug users early during infection

scientific article published on 31 March 2016

HIV-1 Subtype C Gag-Specific T-Cell Responses in Relation to Human Leukocyte Antigens in a Diverse Population of HIV-Infected Ethiopians

article

HIV-1 can persist in aged memory CD4+ T lymphocytes with minimal signs of evolution after 8.3 years of effective highly active antiretroviral therapy

scientific article published in April 2009

HIV-specific CD4+ T cells and viremia: who's in control?

scientific article published on 3 February 2006

HIV-specific CD8+ T cell proliferation is coupled to perforin expression and is maintained in nonprogressors

scientific article published on 07 October 2002

HLA Preferences for Conserved Epitopes: A Potential Mechanism for Hepatitis C Clearance.

scientific article

HLA class I allele promiscuity revisited ⬇️

scientific article published on June 22, 2011

HLA-B molecules target more conserved regions of the HIV-1 proteome

scientific article published on 01 January 2010

High responsiveness of HLA-B57-restricted Gag-specific CD8+ T cells in vitro may contribute to the protective effect of HLA-B57 in HIV-infection

scientific article published in January 2005

Host Gene Expression Kinetics During Treatment of Tuberculosis in HIV-Coinfected Individuals Is Independent of Highly Active Antiretroviral Therapy

article

How age and infection history shape the antigen-specific CD8+ T-cell repertoire: Implications for vaccination strategies in older adults

scientific article published on 20 October 2020

Human herpes virus 6 plasma DNA positivity after hematopoietic stem cell transplantation in children: an important risk factor for clinical outcome.

scientific article published in July 2008

Human herpesvirus type 6 reactivation after haematopoietic stem cell transplantation.

scientific article published on October 2008

Immune activation and collateral damage in AIDS pathogenesis.

scientific article published on 26 September 2013

Immune surveillance of EBV-infected B cells and the development of non-Hodgkin lymphomas in immunocompromised patients

scientific article published on June 2008

Immunological Analysis of Treatment Interruption After Early Highly Active Antiretroviral Therapy ⬇️

scientific article published on 01 December 2010

Immunological effects of shift work in healthcare workers

scientific article published on 03 December 2019

Immunophenotyping of blood lymphocytes at birth, during childhood, and during adulthood in HIV-1-uninfected Ethiopians

scientific article

Impact of delivery mode-associated gut microbiota dynamics on health in the first year of life

scientific article published on 01 November 2019

Impaired recovery of Epstein-Barr virus (EBV)--specific CD8+ T lymphocytes after partially T-depleted allogeneic stem cell transplantation may identify patients at very high risk for progressive EBV reactivation and lymphoproliferative disease

scientific article published on 6 February 2003

In vitro expansion of antigen-specific CD8(+) T cells distorts the T-cell repertoire

scientific article published on 7 February 2014

Infectious reactivation of cytomegalovirus explaining age- and sex-specific patterns of seroprevalence

scientific article published on 26 September 2017

Influence of Donor Cytomegalovirus (CMV) Status on Severity of Viral Reactivation after Allogeneic Stem Cell Transplantation in CMV-Seropositive Recipients ⬇️

scientific article published on April 1, 2011

Influence of HIV Infection on Cytomegalovirus-Specific Immunity: T-Cell Responses to Pp65 and Ie1 before and after Haart May Refect Altered Cytomegalovirus Biology ⬇️

scientific article published on 01 January 2011

Klokwerk + study protocol: An observational study to the effects of night-shift work on body weight and infection susceptibility and the mechanisms underlying these health effects

scientific article

Lack of Epstein-Barr virus- and HIV-specific CD27- CD8+ T cells is associated with progression to viral disease in HIV-infection

scientific article published in October 2002

Long-term highly active antiretroviral therapy in chronic HIV-1 infection: evidence for reconstitution of antiviral immunity.

scientific article

Loss of EBNA1-specific memory CD4+ and CD8+ T cells in HIV-infected patients progressing to AIDS-related non-Hodgkin lymphoma

scientific article published on 12 July 2005

Loss of HIV-1-derived cytotoxic T lymphocyte epitopes restricted by protective HLA-B alleles during the HIV-1 epidemic

scientific article published on September 2011

Management of Epstein-Barr virus (EBV) reactivation after allogeneic stem cell transplantation by simultaneous analysis of EBV DNA load and EBV-specific T cell reconstitution.

scientific article published on 4 May 2006

Measles Virus Epitope Presentation by HLA: Novel Insights into Epitope Selection, Dominance, and Microvariation

scientific article

Mumps infection but not childhood vaccination induces persistent polyfunctional CD8+ T-cell memory

scientific article published on 12 January 2018

Naive CD8⁺ T-cell precursors display structured TCR repertoires and composite antigen-driven selection dynamics

scientific article

Natural controlled HIV infection: preserved HIV-specific immunity despite undetectable replication competent virus

scientific article

Negative Effect of Age, but Not of Latent Cytomegalovirus Infection on the Antibody Response to a Novel Influenza Vaccine Strain in Healthy Adults

scientific article published on 29 January 2018

Novel method for detection of virus-specific CD41+ T cells indicates a decreased EBV-specific CD4+ T cell response in untreated HIV-infected subjects

scientific article

Objectively measured physical activity of hospital shift workers

scientific article

Ongoing Risk Behavior and the Presence of HCV-RNA Affect the Hepatitis C Virus (HCV)-Specific CD4+ T Cell Response ⬇️

scientific article published on May 22, 2013

Pegylated interferon-α monotherapy leads to low response rates in HIV-infected patients with acute hepatitis C.

scientific article published in January 2011

Peripheral T-cell apoptosis is not differentially affected by antiretroviral regimens in HIV-infected patients.

scientific article published on 3 June 2013

Persistent numbers of tetramer+ CD8(+) T cells, but loss of interferon-gamma+ HIV-specific T cells during progression to AIDS

scientific article published on 01 April 2002

Preventing infectious diseases for healthy ageing: The VITAL public-private partnership project

scientific article published on 23 July 2020

Prognostic value of HIV-1 Gag-specific CD4+ T-cell responses for progression to AIDS analyzed in a prospective cohort study

scientific article published on 18 October 2005

Progressive telomere shortening of Epstein-Barr virus-specific memory T cells during HIV infection: contributor to exhaustion?

scientific article published in November 2008

Proteome sampling by the HLA class I antigen processing pathway

scientific article

Rapid reconstitution of CD4 T cells and NK cells protects against CMV-reactivation after allogeneic stem cell transplantation.

scientific article published on 02 August 2016

Recognition of homo- and heterosubtypic variants of influenza A viruses by human CD8+ T lymphocytes

scientific article published on February 2004

Reconstitution of EBV latent but not lytic antigen-specific CD4+ and CD8+ T cells after HIV treatment with highly active antiretroviral therapy

scientific article published in August 2005

Rituximab treatment before reduced-intensity conditioning transplantation associates with a decreased incidence of extensive chronic GVHD.

scientific article published on 16 April 2009

Sequence variations in HIV-1 p24 Gag-derived epitopes can alter binding of KIR2DL2 to HLA-C*03:04 and modulate primary natural killer cell function

scientific article published on June 2014

Shift Work and Respiratory Infections in Health-Care Workers

article

Shift of CMV-specific CD4+ T-cells to the highly differentiated CD45RO-CD27- phenotype parallels loss of proliferative capacity and precedes progression to HIV-related CMV end-organ disease

scientific article published on 06 June 2007

Short- and long-term impact of vaccination against cytomegalovirus: a modeling study

scientific article published on 02 July 2020

Sickness absenteeism, work performance, and healthcare use due to respiratory infections for shift and non-shift workers

scientific article published on 13 October 2020

Significance of senescence for virus-specific memory T cell responses: rapid ageing during chronic stimulation of the immune system

scientific article

Socioeconomic Status Is Associated With Antibody Levels Against Vaccine Preventable Diseases in the Netherlands

Spontaneous outgrowth of EBV-transformed B-cells reflects EBV-specific immunity in vivo; a useful tool in the follow-up of EBV-driven immunoproliferative disorders in allograft recipients

scientific article

Spontaneous outgrowth of EBV-transformed B-cells reflects EBV-specific immunity in vivo; a useful tool in the follow-up of EBV-driven immunoproliferative disorders in allograft recipients

scientific article published in February 2004

Stable pattern of HIV-1 subtype C Gag-specific T-cell responses coincides with slow rate of CD4 T-cell decline in HIV-infected Ethiopians

scientific article published in January 2007

T cell responses to viral infections - opportunities for Peptide vaccination

scientific article published on 16 April 2014

T cell subset and cytokine profiles in human visceral leishmaniasis during active and asymptomatic or sub-clinical infection with Leishmania donovani

scientific article published on 25 August 2005

T-cell responses at baseline and during therapy with peginterferon-alpha and ribavirin are not associated with outcome in chronic hepatitis C infected patients.

scientific article published on 12 June 2010

T-cells and cardiac complications in infectious mononucleosis

scientific article published on 01 March 2012

The association between exposure to different aspects of shift work and metabolic risk factors in health care workers, and the role of chronotype

scientific article published in PLoS ONE

The effect of HIV coinfection, HAART and TB treatment on cytokine/chemokine responses to Mycobacterium tuberculosis (Mtb) antigens in active TB patients and latently Mtb infected individuals.

scientific article

The hallmarks of CMV-specific CD8 T-cell differentiation

scientific article published on 13 April 2019

The immunological phenotype of rituximab-sensitive chronic graft-versus-host disease: a phase II study

scientific article

The mediating role of sleep, physical activity, and diet in the association between shift work and respiratory infections

scientific article published on 07 April 2020

The presence of protective cytotoxic T lymphocytes does not correlate with shorter lifespans of productively infected cells in HIV-1 infection.

scientific article

Tight regulation of the Epstein-Barr virus setpoint: interindividual differences in Epstein-Barr virus DNA load are conserved after HIV infection

scientific article published in January 2008

Tuberculin skin test conversion and reactivity rates among adults with and without human immunodeficiency virus in urban settings in Ethiopia

scientific article

VDJdb: a curated database of T-cell receptor sequences with known antigen specificity

scientific article published on September 2017

Vaccines to Protect Older Adults against Pneumococcal Disease

scientific article published on 09 April 2020

Varicella vaccination in HIV-1-infected children after immune reconstitution

scientific article published on 01 November 2006

Viral replication capacity as a correlate of HLA B57/B5801-associated nonprogressive HIV-1 infection

scientific article published on 01 September 2007

Virologic and immunologic outcome of HAART in Human Immunodeficiency Virus (HIV)-1 infected patients with and without tuberculosis (TB) and latent TB infection (LTBI) in Addis Ababa, Ethiopia

scientific article published on 10 July 2013

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