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List of works by Peter S Nelson

17-Gene Genomic Prostate Score Test Results in the Canary Prostate Active Surveillance Study (PASS) Cohort

scientific article published on 04 March 2020

A Novel Flavonoid Composition Targets Androgen Receptor Signaling and Inhibits Prostate Cancer Growth in Preclinical Models.

scientific article published on 4 July 2018

A Pilot Study of Clinical Targeted Next Generation Sequencing for Prostate Cancer: Consequences for Treatment and Genetic Counseling

scientific article published on 21 June 2016

A causal role for ERG in neoplastic transformation of prostate epithelium.

scholarly article

A comparative assessment of clinical whole exome and transcriptome profiling across sequencing centers: implications for precision cancer medicine

scientific article

A comparison of prostate cancer cell transcriptomes in 2D monoculture vs 3D xenografts identify consistent gene expression alterations associated with tumor microenvironments

scientific article published on 18 February 2020

A framework for clinical cancer subtyping from nucleosome profiling of cell-free DNA

scientific article published in 2022

A gain-of-function mutation in DHT synthesis in castration-resistant prostate cancer

scientific article published on August 2013

A model for the design and construction of a resource for the validation of prognostic prostate cancer biomarkers: the Canary Prostate Cancer Tissue Microarray

scientific article published on January 2013

A molecular correlate to the Gleason grading system for prostate adenocarcinoma

scholarly article

A multicenter study shows PTEN deletion is strongly associated with seminal vesicle involvement and extracapsular extension in localized prostate cancer

scientific article published on 4 May 2015

A neuroendocrine/small cell prostate carcinoma xenograft-LuCaP 49

scientific article published on August 2002

A phase I study of niclosamide in combination with enzalutamide in men with castration-resistant prostate cancer.

scientific article published in June 2018

A proteolytic modification of AIM promotes its renal excretion.

scientific article published on 08 December 2016

A targeted proteomics–based pipeline for verification of biomarkers in plasma ⬇️

scientific article published on June 19, 2011

A three-marker FISH panel detects more genetic aberrations of AR, PTEN and TMPRSS2/ERG in castration-resistant or metastatic prostate cancers than in primary prostate tumors

scientific article

AR variant ARv567es induces carcinogenesis in a novel transgenic mouse model of prostate cancer

scientific article

ARv7 Represses Tumor-Suppressor Genes in Castration-Resistant Prostate Cancer

scientific article published on 14 February 2019

Abiraterone treatment in castration-resistant prostate cancer selects for progesterone responsive mutant androgen receptors

scientific article

Activation of MAPK Signaling by CXCR7 Leads to Enzalutamide Resistance in Prostate Cancer

scientific article published on 05 April 2019

African American Race is Not Associated with Risk of Reclassification during Active Surveillance: Results from the Canary Prostate Cancer Active Surveillance Study

scientific article published on 25 October 2019

Alternative splicing of LSD1+8a in neuroendocrine prostate cancer is mediated by SRRM4

scientific article published on 11 May 2020

Analysis of testosterone and dihydrotestosterone from biological fluids as the oxime derivatives using high-performance liquid chromatography/tandem mass spectrometry

scientific article published on 01 January 2007

Analytic validation of a clinical-grade PTEN immunohistochemistry assay in prostate cancer by comparison with PTEN FISH.

scientific article published on 13 May 2016

Androgen Receptor Deregulation Drives Bromodomain-Mediated Chromatin Alterations in Prostate Cancer

scientific article published on June 2017

Androgen Receptor Pathway-Independent Prostate Cancer Is Sustained through FGF Signaling

scientific article

Androgen Receptor Variants Occur Frequently in Castration Resistant Prostate Cancer Metastases ⬇️

scientific article published on November 17, 2011

Androgen action and metabolism in prostate cancer ⬇️

scientific article published on March 20, 2012

Androgen deprivation therapy: progress in understanding mechanisms of resistance and optimizing androgen depletion

scientific article

Androgen receptor (AR) expression in AR-negative prostate cancer cells results in differential effects of DHT and IGF-I on proliferation and AR activity between localized and metastatic tumors

scientific article published on November 2004

Androgen receptor gene expression in prostate cancer is directly suppressed by the androgen receptor through recruitment of lysine-specific demethylase 1.

scientific article published on October 2011

Androgen receptor splice variant-7 expression emerges with castration resistance in prostate cancer

scientific article published on 26 November 2018

Anti-Depressant Therapy Brightens the Outlook for Prostate Cancer Bone Metastases

scientific article published in March 2017

Association of Clonal Hematopoiesis in DNA Repair Genes With Prostate Cancer Plasma Cell-free DNA Testing Interference

scientific article published on 05 November 2020

Association of Tissue Abiraterone Levels and SLCO Genotype with Intraprostatic Steroids and Pathologic Response in Men with High-Risk Localized Prostate Cancer.

scientific article published on 7 April 2017

Association of megalin genetic polymorphisms with prostate cancer risk and prognosis

scientific article

Association of prostate cancer SLCO gene expression with Gleason grade and alterations following androgen deprivation therapy

scientific article published on 19 March 2019

Biallelic Inactivation of BRCA2 in Platinum-sensitive Metastatic Castration-resistant Prostate Cancer

scientific article published on 23 December 2015

Boolean analysis identifies CD38 as a biomarker of aggressive localized prostate cancer

scientific article published on 5 January 2018

CCL2 is induced by chemotherapy and protects prostate cancer cells from docetaxel-induced cytotoxicity

scientific article published on March 2010

CD90/THY1 is overexpressed in prostate cancer-associated fibroblasts and could serve as a cancer biomarker

scientific article

Cabozantinib can block growth of neuroendocrine prostate cancer patient-derived xenografts by disrupting tumor vasculature

scientific article published on 20 January 2021

Canary Prostate Active Surveillance Study: design of a multi-institutional active surveillance cohort and biorepository

scientific article published on 16 September 2009

Castration resistance in human prostate cancer is conferred by a frequently occurring androgen receptor splice variant

scientific article

Castration-resistant prostate cancer: targeting androgen metabolic pathways in recurrent disease

scientific article published on May 2009

Cell type-specific analyses for identifying prostate cancer biomarkers

scientific article

Cells Comprising the Prostate Cancer Microenvironment Lack Recurrent Clonal Somatic Genomic Aberrations

scientific article published on 11 January 2016

Cellular Adhesion Promotes Prostate Cancer Cells Escape from Dormancy

scientific article published on 19 June 2015

Characterization and comparative analyses of transcriptomes from the normal and neoplastic human prostate

scientific article published in August 2004

Characterization of an Abiraterone Ultraresponsive Phenotype in Castration-Resistant Prostate Cancer Patient-Derived Xenografts

scientific article published on 19 December 2016

Characterization of chemical constituents in Scutellaria baicalensis with antiandrogenic and growth-inhibitory activities toward prostate carcinoma ⬇️

scientific article published in May 2005

Characterization of osteoblastic and osteolytic proteins in prostate cancer bone metastases ⬇️

scientific article published on January 17, 2013

Characterization of single disseminated prostate cancer cells reveals tumor cell heterogeneity and identifies dormancy associated pathways

scientific article published on October 2014

Characterizing the molecular features of ERG-positive tumors in primary and castration resistant prostate cancer

scientific article

Chemotherapy-induced monoamine oxidase expression in prostate carcinoma functions as a cytoprotective resistance enzyme and associates with clinical outcomes

scientific article

Circulating microRNA Profiling Identifies a Subset of Metastatic Prostate Cancer Patients with Evidence of Cancer-Associated Hypoxia ⬇️

scientific article published on July 30, 2013

Circulating microRNAs as stable blood-based markers for cancer detection

scientific article

Clinical Outcome of Prostate Cancer Patients with Germline DNA Repair Mutations: Retrospective Analysis from an International Study.

scientific article published on 29 January 2018

Clinical determinants for successful circulating tumor DNA analysis in prostate cancer

scientific article published on 13 March 2019

Combination treatment of prostate cancer with FGF receptor and AKT kinase inhibitors

scientific article published on 20 December 2016

Combined MYC Activation and Pten Loss Are Sufficient to Create Genomic Instability and Lethal Metastatic Prostate Cancer

scientific article

Combined TP53 and RB1 Loss Promotes Prostate Cancer Resistance to a Spectrum of Therapeutics and Confers Vulnerability to Replication Stress

scientific article published on 01 May 2020

Comparative analyses of chromosome alterations in soft-tissue metastases within and across patients with castration-resistant prostate cancer

scientific article published on 22 September 2009

Comparison of four next generation sequencing platforms for fusion detection: Oncomine by ThermoFisher, AmpliSeq by illumina, FusionPlex by ArcherDX, and QIAseq by QIAGEN

scientific article published on 07 March 2020

Complex MSH2 and MSH6 mutations in hypermutated microsatellite unstable advanced prostate cancer

scientific article

Conserved gene expression programs integrate mammalian prostate development and tumorigenesis

scientific article published on 17 February 2009

Continued 5α-Reductase Inhibitor Use after Prostate Cancer Diagnosis and the Risk of Reclassification and Adverse Pathological Outcomes in the PASS

scientific article published on 01 January 2019

Contribution of Adrenal Glands to Intratumor Androgens and Growth of Castration-Resistant Prostate Cancer

scientific article published on 04 September 2018

Correction: A phase I study of niclosamide in combination with enzalutamide in men with castration-resistant prostate cancer

scientific article published in PLoS ONE

Correction: Activation of MAPK Signaling by CXCR7 Leads to Enzalutamide Resistance in Prostate Cancer

scientific article published on 01 May 2020

Correlation of mRNA and protein levels: cell type-specific gene expression of cluster designation antigens in the prostate

scientific article

DNA Damage Induces a Secretory Program in the Quiescent TME that Fosters Adverse Cancer Phenotypes

scientific article published on 29 March 2017

DNA damage induces GDNF secretion in the tumor microenvironment with paracrine effects promoting prostate cancer treatment resistance.

scientific article

DNA-Repair Gene Mutations in Metastatic Prostate Cancer

scientific article published on 01 November 2016

Data from Downregulation of <i>Dipeptidyl Peptidase 4</i> Accelerates Progression to Castration-Resistant Prostate Cancer

Data from Downregulation of <i>Dipeptidyl Peptidase 4</i> Accelerates Progression to Castration-Resistant Prostate Cancer

scientific article published on 31 March 2023

Deconstructing tumor heterogeneity: the stromal perspective

scientific article published on 06 October 2020

Delayed dark adaptation in 11-cis-retinol dehydrogenase-deficient mice: a role of RDH11 in visual processes in vivo

scientific article

Development and validation of a scalable next-generation sequencing system for assessing relevant somatic variants in solid tumors

scientific article published on April 2015

Development, validation and application of a stable isotope dilution liquid chromatography electrospray ionization/selected reaction monitoring/mass spectrometry (SID-LC/ESI/SRM/MS) method for quantification of keto-androgens in human serum ⬇️

scientific article published on July 10, 2013

Dickkopf-1 Can Lead to Immune Evasion in Metastatic Castration-Resistant Prostate Cancer

scientific article published on 29 September 2020

Diethylstilbestrol and docetaxel: a Phase II study of tubulin active agents in patients with metastatic, androgen-independent prostate cancer

scientific article published on 01 September 2007

Differential expression of angiogenesis associated genes in prostate cancer bone, liver and lymph node metastases

scientific article published on 31 October 2007

Differential expression of the alpha2 chain of the interleukin-13 receptor in metastatic human prostate cancer ARCaPM cells

scientific article published on June 2010

Differential gene expression in benign prostate epithelium of men with and without prostate cancer: evidence for a prostate cancer field effect

scientific article

Digital expression profiles of the prostate androgen-response program

scientific article

Dihydrotestosterone administration does not increase intraprostatic androgen concentrations or alter prostate androgen action in healthy men: a randomized-controlled trial

scientific article

Distinct transcriptional programs mediated by the ligand-dependent full-length androgen receptor and its splice variants in castration-resistant prostate cancer.

scientific article

Docetaxel-related toxicity in metastatic hormone-sensitive and metastatic castration-resistant prostate cancer

scientific article

Downregulation of Dipeptidyl Peptidase 4 Accelerates Progression to Castration-Resistant Prostate Cancer

scientific article published on 21 September 2018

Dual-substrate specificity short chain retinol dehydrogenases from the vertebrate retina

scientific article

Durable Response of Enzalutamide-resistant Prostate Cancer to Supraphysiological Testosterone Is Associated with a Multifaceted Growth Suppression and Impaired DNA Damage Response Transcriptomic Program in Patient-derived Xenografts

scientific article published on 19 June 2019

Duration of first off-treatment interval is prognostic for time to castration resistance and death in men with biochemical relapse of prostate cancer treated on a prospective trial of intermittent androgen deprivation

scientific article

ERG Activates the YAP1 Transcriptional Program and Induces the Development of Age-Related Prostate Tumors.

scientific article published on June 2015

EZH2 cooperates with gain-of-function p53 mutants to promote cancer growth and metastasis

scientific article published on 05 February 2019

Effect of medical castration on CD4+ CD25+ T cells, CD8+ T cell IFN-gamma expression, and NK cells: a physiological role for testosterone and/or its metabolites

scientific article

Effect of testosterone replacement therapy on prostate tissue in men with late-onset hypogonadism: a randomized controlled trial

scientific article

Effects of the herbal extract PC-SPES on microtubule dynamics and paclitaxel-mediated prostate tumor growth inhibition

scientific article published in November 2002

Epigenetic signature of Gleason score and prostate cancer recurrence after radical prostatectomy

scientific article

Epithelial mesenchymal-like transition occurs in a subset of cells in castration resistant prostate cancer bone metastases

scientific article

ErbB2 Signaling Increases Androgen Receptor Expression in Abiraterone-Resistant Prostate Cancer

scientific article published on 2 March 2016

Erratum for Garcia et al., Pten Null Prostate Epithelium Promotes Localized Myeloid-Derived Suppressor Cell Expansion and Immune Suppression during Tumor Initiation and Progression.

scientific article published in September 2014

Establishing a cryopreservation protocol for patient-derived xenografts of prostate cancer

scientific article published on 18 June 2019

Estradiol suppresses tissue androgens and prostate cancer growth in castration resistant prostate cancer

scientific article

Estrogen effects on tubulin expression and taxane mediated cytotoxicity in prostate cancer cells

scientific article published in October 2005

Evaluating the Four Kallikrein Panel of the 4Kscore for Prediction of High-grade Prostate Cancer in Men in the Canary Prostate Active Surveillance Study

scientific article published on 23 November 2016

Evaluation of ERG and SPINK1 by Immunohistochemical Staining and Clinicopathological Outcomes in a Multi-Institutional Radical Prostatectomy Cohort of 1067 Patients.

scientific article published on 14 July 2015

Evidence that the human gene for prostate short-chain dehydrogenase/reductase (PSDR1) encodes a novel retinal reductase (RalR1).

scientific article

Exome sequencing identifies a spectrum of mutation frequencies in advanced and lethal prostate cancers

scientific article

Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancer

scientific article

Exploitation of CD133 for the Targeted Imaging of Lethal Prostate Cancer

scientific article published on 15 November 2019

Exploiting AR-Regulated Drug Transport to Induce Sensitivity to the Survivin Inhibitor YM155.

scientific article published in May 2017

Expressed sequence tag profiling identifies developmental and anatomic partitioning of gene expression in the mouse prostate

scientific article

Expression of STAT3 in Prostate Cancer Metastases.

scientific article published on 22 June 2016

Expression of cell cycle-regulated genes and prostate cancer prognosis in a population-based cohort

scientific article (publication date: September 2015)

FOXA2 promotes prostate cancer growth in the bone

scientific article published on 15 September 2020

Fourth International Conference on Innovations and Challenges in Prostate Cancer: Prevention, Detection and Treatment

scientific article

Gene expression in the LNCaP human prostate cancer progression model: progression associated expression in vitro corresponds to expression changes associated with prostate cancer progression in vivo

scientific article published on 23 February 2006

Gene expression panel predicts metastatic-lethal prostate cancer outcomes in men diagnosed with clinically localized prostate cancer

scientific article published on 19 October 2016

Genetic background influences murine prostate gene expression: implications for cancer phenotypes

scientific article published on January 2007

Genomic Characterization of Prostatic Ductal Adenocarcinoma Identifies a High Prevalence of DNA Repair Gene Mutations

scientific article published on 18 April 2019

Genomic alterations indicate tumor origin and varied metastatic potential of disseminated cells from prostate cancer patients

scientific article

Genomic correlates of clinical outcome in advanced prostate cancer.

scientific article

Genomic distinctions between metastatic lower and upper tract urothelial carcinoma revealed through rapid autopsy

scientific article published on 30 May 2019

Genomic strategy for targeting therapy in castration-resistant prostate cancer

scientific article

HE3235 inhibits growth of castration-resistant prostate cancer

scientific article

HPV16 induces penile intraepithelial neoplasia and squamous cell carcinoma in transgenic mice: first mouse model for HPV-related penile cancer

scientific article published on 03 June 2020

High-Resolution Genomic Profiling of Disseminated Tumor Cells in Prostate Cancer

scientific article

Histologic Grading of Prostatic Adenocarcinoma Can Be Further Optimized: Analysis of the Relative Prognostic Strength of Individual Architectural Patterns in 1275 Patients From the Canary Retrospective Cohort

scientific article

Human prostate epithelial cell-type cDNA libraries and prostate expression patterns

scientific article

ID1 enhances docetaxel cytotoxicity in prostate cancer cells through inhibition of p21.

scientific article published on 13 April 2010

Identification and characterization of novel SNPs in CHEK2 in Ashkenazi Jewish men with prostate cancer

scientific article

Identification of Combinatorial Genomic Abnormalities Associated with Prostate Cancer Early Recurrence

scientific article published on 2 January 2016

Identification of Therapeutic Vulnerabilities in Small-cell Neuroendocrine Prostate Cancer

scientific article published on 05 December 2019

Imaging Fibroblast Activation Protein Alpha improves diagnosis of metastatic Prostate Cancer with Positron Emission Tomography

scientific article published on 07 July 2020

Immunogenomic analyses associate immunological alterations with mismatch repair defects in prostate cancer

scientific article published on 01 November 2018

Immunogenomic analyses associate immunological alterations with mismatch repair defects in prostate cancer

scientific article published on 04 September 2018

Impact of male hormonal contraception on prostate androgens and androgen action in healthy men: a randomized, controlled trial.

scientific article

Impact of mutations in homologous recombination repair genes on treatment outcomes for metastatic castration resistant prostate cancer

scientific article published on 30 September 2020

Inactivation of CDK12 Delineates a Distinct Immunogenic Class of Advanced Prostate Cancer

scientific article published on 01 June 2018

Incidence of second malignancies after external beam radiotherapy for clinical stage I testicular seminoma ⬇️

scientific article published on August 22, 2011

Increased expression of osteopontin contributes to the progression of prostate cancer

scientific article published in January 2006

Increased manganese superoxide dismutase (SOD-2) is part of the mechanism for prostate tumor suppression by Mac25/insulin-like growth factor binding-protein-related protein-1

scientific article (publication date: 20 February 2003)

Influence of surgical manipulation on prostate gene expression: implications for molecular correlates of treatment effects and disease prognosis

scientific article

Influenza and SARS-coronavirus activating proteases TMPRSS2 and HAT are expressed at multiple sites in human respiratory and gastrointestinal tracts

scientific article (publication date: 2012)

Inherited DNA-Repair Gene Mutations in Men with Metastatic Prostate Cancer

scientific article published on 06 July 2016

Inhibition of androgen-independent prostate cancer by estrogenic compounds is associated with increased expression of immune-related genes

scientific article

Integrative Analysis of N-Linked Human Glycoproteomic Data Sets Reveals PTPRF Ectodomain as a Novel Plasma Biomarker Candidate for Prostate Cancer ⬇️

scientific article published on April 19, 2012

Integrative Clinical Genomics of Advanced Prostate Cancer

scientific article

Integrative clinical genomics of advanced prostate cancer

scientific article

Intense androgen-deprivation therapy with abiraterone acetate plus leuprolide acetate in patients with localized high-risk prostate cancer: results of a randomized phase II neoadjuvant study

scientific article

Inter- and intra-tumor heterogeneity of metastatic prostate cancer determined by digital spatial gene expression profiling

scientific article published on 03 March 2021

Intracrine androgen metabolism in prostate cancer progression: mechanisms of castration resistance and therapeutic implications

scientific article published on April 2008

Intraprostatic Steroidogenic Enzymes – Letter ⬇️

scientific article published on October 12, 2010

Intraprostatic androgens and androgen-regulated gene expression persist after testosterone suppression: therapeutic implications for castration-resistant prostate cancer

scientific article published on 01 May 2007

Intratumoral de novo steroid synthesis activates androgen receptor in castration-resistant prostate cancer and is upregulated by treatment with CYP17A1 inhibitors ⬇️

scientific article published on August 25, 2011

Isolation and characterization of human and mouse WDR19,a novel WD-repeat protein exhibiting androgen-regulated expression in prostate epithelium

scientific article published in September 2003

Isolation and characterization of the murine prostate short-chain dehydrogenase/reductase 1 (Psdr1) gene, a new member of the short-chain steroid dehydrogenase/reductase family

scientific article

KLK31P is a novel androgen regulated and transcribed pseudogene of kallikreins that is expressed at lower levels in prostate cancer cells than in normal prostate cells

scientific article published on June 2006

Loss of Expression of AZGP1 Is Associated With Worse Clinical Outcomes in a Multi-Institutional Radical Prostatectomy Cohort

scientific article published on 21 June 2016

Loss of stearoyl-CoA desaturase expression is a frequent event in prostate carcinoma

scientific article

Low-fat, low-glycemic load diet and gene expression in human prostate epithelium: a feasibility study of using cDNA microarrays to assess the response to dietary intervention in target tissues

scientific article

LuCaP 35: A new model of prostate cancer progression to androgen independence ⬇️

scientific article published on June 1, 2003

LuCaP Prostate Cancer Patient-Derived Xenografts Reflect the Molecular Heterogeneity of Advanced Disease an--d Serve as Models for Evaluating Cancer Therapeutics.

scientific article published on 3 February 2017

MTOR regulates the pro-tumorigenic senescence-associated secretory phenotype by promoting IL1A translation

scientific article

MUC1 Expression by Immunohistochemistry Is Associated with Adverse Pathologic Features in Prostate Cancer: A Multi-Institutional Study

scientific article

Magnetic Resonance Imaging for the Detection of High-Grade Cancer in the Canary Prostate Active Surveillance Study

scientific article published on 28 April 2020

Maintenance of intratumoral androgens in metastatic prostate cancer: a mechanism for castration-resistant tumor growth

scientific article published on June 2008

Merkel cell polyomavirus is not detected in prostate cancers, surrounding stroma, or benign prostate controls

scientific article

Metastatic progression of prostate cancer and e-cadherin regulation by zeb1 and SRC family kinases.

scientific article

Microarray analysis and tumor classification

scientific article published on 01 August 2006

Microsatellite instability in prostate cancer by PCR or next-generation sequencing.

scientific article published on 17 April 2018

Mismatch repair deficiency in metastatic prostate cancer: Response to PD-1 blockade and standard therapies

scientific article published on 26 May 2020

Mismatch repair deficiency may be common in ductal adenocarcinoma of the prostate

scientific article published on 15 October 2016

Mismatch repair enzyme expression in primary and castrate resistant prostate cancer

scientific article published on 12 September 2016

Mitochondrial DNA mutation stimulates prostate cancer growth in bone stromal environment

scientific article

Molecular alterations in prostate carcinomas that associate with in vivo exposure to chemotherapy: identification of a cytoprotective mechanism involving growth differentiation factor 15.

scientific article published in October 2007

Molecular characterization of prostatic small-cell neuroendocrine carcinoma

scientific article (publication date: April 2003)

Molecular determinants of response to high-dose androgen therapy in prostate cancer

scientific article published on 03 October 2019

Molecular effects of the herbal compound PC-SPES: identification of activity pathways in prostate carcinoma.

scientific article

Molecular profiling stratifies diverse phenotypes of treatment-refractory metastatic castration-resistant prostate cancer

scientific article published on 30 July 2019

Multiplexed functional genomic analysis of 5' untranslated region mutations across the spectrum of prostate cancer

scientific article published on 09 July 2021

Negative selection: a method for obtaining low-abundance cDNAs using high-density cDNA clone arrays

scientific article published on 01 December 1999

Neoadjuvant Enzalutamide Prior to Prostatectomy

scientific article published on 9 November 2016

Neoadjuvant-Intensive Androgen Deprivation Therapy Selects for Prostate Tumor Foci with Diverse Subclonal Oncogenic Alterations

scientific article published on 19 June 2018

Novel Junction-specific and Quantifiable In Situ Detection of AR-V7 and its Clinical Correlates in Metastatic Castration-resistant Prostate Cancer

scientific article published on 30 August 2017

ONECUT2 is a targetable master regulator of lethal prostate cancer that suppresses the androgen axis

scientific article published on 26 November 2018

Outcomes of Active Surveillance for Clinically Localized Prostate Cancer in the Prospective, Multi-Institutional Canary PASS Cohort

scientific article

PEG10 Promoter-Driven Expression of Reporter Genes Enables Molecular Imaging of Lethal Prostate Cancer

scientific article published on 17 September 2019

PLZF, a tumor suppressor genetically lost in metastatic castration-resistant prostate cancer, is a mediator of resistance to androgen deprivation therapy

scientific article published on 25 March 2015

PPP2R2C Loss Promotes Castration-Resistance and Is Associated with Increased Prostate Cancer-Specific Mortality ⬇️

scientific article published on March 14, 2013

PTEN Loss as Determined by Clinical-grade Immunohistochemistry Assay Is Associated with Worse Recurrence-free Survival in Prostate Cancer

scientific article published on June 2016

PTEN loss is associated with prostate cancer recurrence and alterations in tumor DNA methylation profiles.

scientific article

Patterns of structural variation define prostate cancer across disease states

scientific article published in 2022

Performance of PCA3 and TMPRSS2:ERG urinary biomarkers in prediction of biopsy outcome in the Canary Prostate Active Surveillance Study (PASS)

scientific article published on 21 January 2019

Persistent intraprostatic androgen concentrations after medical castration in healthy men.

scientific article

Phenotypic analysis of mice lacking the Tmprss2-encoded protease

scientific article

Polyclonal BRCA2 Reversion Mutations Detected in Circulating Tumor DNA After Platinum Chemotherapy in a Patient With Metastatic Prostate Cancer

scientific article published on 14 February 2018

Post prostatectomy outcomes of patients with high-risk prostate cancer treated with neoadjuvant androgen blockade

scientific article published on 20 December 2017

PrLZ, a novel prostate-specific and androgen-responsive gene of the TPD52 family, amplified in chromosome 8q21.1 and overexpressed in human prostate cancer

scientific article (publication date: March 2004)

Precision Medicine in Active Surveillance for Prostate Cancer: Development of the Canary-Early Detection Research Network Active Surveillance Biopsy Risk Calculator

scientific article

Prognostic Genomic Biomarkers in Patients With Localized Prostate Cancer: Is Rising Utilization Justified by Evidence?

scientific article published on 25 November 2020

Prognostic value of ERG oncoprotein in prostate cancer recurrence and cause‐specific mortality ⬇️

scientific article published on January 17, 2013

Prostate Cancer Disseminated Tumor Cells are Rarely Detected in the Bone Marrow of Localized Patients Undergoing Radical Prostatectomy Across Multiple Rare Cell Detection Platforms

scientific article published on 12 January 2018

Prostate Cancer Screening in a New Era of Genetics

scientific article

Prostate cancer cell phenotypes based on AGR2 and CD10 expression

scientific article published on 25 January 2013

Prostate cancer characteristics associated with response to pre-receptor targeting of the androgen axis

scientific article

Prostate cancer derived prostatic acid phosphatase promotes an osteoblastic response in the bone microenvironment

scientific article

Prostate cancer-associated gene expression alterations determined from needle biopsies

scientific article

Prostate tissue androgens: history and current clinical relevance

scientific article published on 27 May 2008

Prostate-specific deletion of the murine Pten tumor suppressor gene leads to metastatic prostate cancer

scientific journal article

Proteome and transcriptome profiles of a Her2/Neu-driven mouse model of breast cancer

scientific article

Publisher Correction: The long tail of oncogenic drivers in prostate cancer

scientific article published on 01 July 2019

Quantitative proteomic analysis of proteins released by neoplastic prostate epithelium

scientific article published on January 2004

Rapid induction of androgen receptor splice variants by androgen deprivation in prostate cancer.

scientific article published on 21 January 2014

Reduced tumor necrosis factor receptor-associated death domain expression is associated with prostate cancer progression

scientific article

Refined Analysis of Prostate-specific Antigen Kinetics to Predict Prostate Cancer Active Surveillance Outcomes

scientific article published on 9 February 2018

Regulation of CEACAM5 and therapeutic efficacy of an anti-CEACAM5-SN38 antibody-drug conjugate in neuroendocrine prostate cancer

scientific article published on 16 November 2020

Regulation of global gene expression in the bone marrow microenvironment by androgen: androgen ablation increases insulin-like growth factor binding protein-5 expression

scientific article

Regulation of hepatocyte activator inhibitor-1 expression by androgen and oncogenic transformation in the prostate

scientific article

Reply by Authors

scientific article published on 17 January 2020

Reprogramming of the FOXA1 cistrome in treatment-emergent neuroendocrine prostate cancer

scientific article published on 30 March 2021

Resistance to CYP17A1 inhibition with abiraterone in castration-resistant prostate cancer: induction of steroidogenesis and androgen receptor splice variants

scientific article

Response of the insulin-like growth factor (IGF) system to IGF-IR inhibition and androgen deprivation in a neoadjuvant prostate cancer trial: effects of obesity and androgen deprivation

scientific article published on 26 March 2013

Retinol dehydrogenase 11 is essential for the maintenance of retinol homeostasis in liver and testis in mice

scientific article published on 22 March 2018

Role of Surveillance Biopsy with No Cancer as a Prognostic Marker for Reclassification: Results from the Canary Prostate Active Surveillance Study.

scientific article published on 9 February 2018

Role of androgen receptor splice variant-7 (AR-V7) in prostate cancer resistance to 2nd-generation androgen receptor signaling inhibitors

scientific article published on 28 September 2020

SRRM4 Expression and the Loss of REST Activity May Promote the Emergence of the Neuroendocrine Phenotype in Castration-Resistant Prostate Cancer

scientific article

Screening Men at Increased Risk for Prostate Cancer Diagnosis: Model Estimates of Benefits and Harms

scientific article published on 14 October 2016

Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor

scientific article (publication date: 2 December 2008)

Single cell transcriptomic analysis of prostate cancer cells ⬇️

scientific article published on February 16, 2013

Spheroid culture of LuCaP 136 patient-derived xenograft enables versatile preclinical models of prostate cancer.

scientific article published on 12 February 2016

Spheroid culture of LuCaP 147 as an authentic preclinical model of prostate cancer subtype with SPOP mutation and hypermutator phenotype

scientific article

Structural Alterations Driving Castration-Resistant Prostate Cancer Revealed by Linked-Read Genome Sequencing

scientific article published on 18 June 2018

Substantial interindividual and limited intraindividual genomic diversity among tumors from men with metastatic prostate cancer

scientific article published on 29 February 2016

Substrates of the prostate-specific serine protease prostase/KLK4 defined by positional-scanning peptide libraries

scientific article published in January 2005

Subtype heterogeneity and epigenetic convergence in neuroendocrine prostate cancer

scientific article published on 01 October 2021

Supplementary Figures S1-S10 from Downregulation of <i>Dipeptidyl Peptidase 4</i> Accelerates Progression to Castration-Resistant Prostate Cancer

Supplementary Figures S1-S10 from Downregulation of <i>Dipeptidyl Peptidase 4</i> Accelerates Progression to Castration-Resistant Prostate Cancer

scientific article published on 31 March 2023

Supplementary Materials and Methods from Downregulation of <i>Dipeptidyl Peptidase 4</i> Accelerates Progression to Castration-Resistant Prostate Cancer

Supplementary Materials and Methods from Downregulation of <i>Dipeptidyl Peptidase 4</i> Accelerates Progression to Castration-Resistant Prostate Cancer

scientific article published on 31 March 2023

Supplementary Tables S1 - S6 from Downregulation of <i>Dipeptidyl Peptidase 4</i> Accelerates Progression to Castration-Resistant Prostate Cancer

scientific article published on 31 March 2023

Supplementary Tables S1 - S6 from Downregulation of <i>Dipeptidyl Peptidase 4</i> Accelerates Progression to Castration-Resistant Prostate Cancer

scientific article published on 31 March 2023

Suppression of growth and tumorigenicity in the prostate tumor cell line M12 by overexpression of the transcription factor SOX9.

scientific article

Supraphysiologic Testosterone Therapy in the Treatment of Prostate Cancer: Models, Mechanisms and Questions

scientific article published on 6 December 2017

Supraphysiological androgens suppress prostate cancer growth through androgen receptor-mediated DNA damage

scientific article published on 16 July 2019

TMPRSS2 and COVID-19: Serendipity or opportunity for intervention?

scientific article published on 10 April 2020

Tailoring Intensity of Active Surveillance for Low-Risk Prostate Cancer Based on Individualized Prediction of Risk Stability

scientific article published on 27 August 2020

Targetable mechanisms driving immunoevasion of persistent senescent cells link chemotherapy-resistant cancer to aging

scientific article published on 11 June 2019

Targeted androgen pathway suppression in localized prostate cancer: a pilot study

scientific article

Targeting RET Kinase in Neuroendocrine Prostate Cancer

scientific article published on 27 May 2020

Testosterone accumulation in prostate cancer cells is enhanced by facilitated diffusion

scientific article published on 02 August 2019

Testosterone regulates tight junction proteins and influences prostatic autoimmune responses

scientific article

The Aged Microenvironment Influences the Tumorigenic Potential of Malignant Prostate Epithelial Cells

scientific article published on 17 September 2018

The DHEA-sulfate depot following P450c17 inhibition supports the case for AKR1C3 inhibition in high risk localized and advanced castration resistant prostate cancer

scientific article published on 13 December 2014

The Role of Lineage Plasticity in Prostate Cancer Therapy Resistance

scientific article published on 30 July 2019

The androgen receptor regulates a druggable translational regulon in advanced prostate cancer

scientific article published on 01 July 2019

The androgen-regulated protease TMPRSS2 activates a proteolytic cascade involving components of the tumor microenvironment and promotes prostate cancer metastasis.

scientific article

The androgen/androgen receptor axis in prostate cancer ⬇️

scientific article published on May 1, 2012

The contributions of normal variation and genetic background to mammalian gene expression

scientific article

The effects of aging on the molecular and cellular composition of the prostate microenvironment

scientific article

The expression of osteoclastogenesis-associated factors and osteoblast response to osteolytic prostate cancer cells

scientific article

The gene expression program of prostate fibroblast senescence modulates neoplastic epithelial cell proliferation through paracrine mechanisms

scientific article published in January 2006

The human (PEDB) and mouse (mPEDB) Prostate Expression Databases ⬇️

scientific article published on January 1, 2002

The landscape of somatic chromosomal copy number aberrations in GEM models of prostate carcinoma

scientific article published on 8 October 2014

The long tail of oncogenic drivers in prostate cancer.

scientific article published on 2 April 2018

The monoamine oxidase A gene promoter repeat and prostate cancer risk

scientific article

The program of androgen-responsive genes in neoplastic prostate epithelium

scientific article

The retinoblastoma tumor suppressor controls androgen signaling and human prostate cancer progression ⬇️

scientific article published on November 22, 2010

The role of tissue microarrays in prostate cancer biomarker discovery

scientific article

Timing of Adverse Prostate Cancer Reclassification on First Surveillance Biopsy: Results from the Canary Prostate Cancer Active Surveillance Study

scientific article published on 31 October 2016

Tissue-specific consequences of cyclin D1 overexpression in prostate cancer progression.

scientific article published on September 2007

Tmprss2 is essential for influenza H1N1 virus pathogenesis in mice.

scientific article

Transforming Growth Factor-{beta}-Stimulated Clone-22 Is an Androgen-Regulated Gene That Enhances Apoptosis in Prostate Cancer following Insulin-Like Growth Factor-I Receptor Inhibition

scientific article published on December 2009

Treatment-induced damage to the tumor microenvironment promotes prostate cancer therapy resistance through WNT16B.

scientific article

Trial Design and Objectives for Castration-Resistant Prostate Cancer: Updated Recommendations From the Prostate Cancer Clinical Trials Working Group 3

scientific article

Truncation and constitutive activation of the androgen receptor by diverse genomic rearrangements in prostate cancer.

scientific article

Tumor Microenvironment–Derived Proteins Dominate the Plasma Proteome Response during Breast Cancer Induction and Progression ⬇️

scientific article published on June 8, 2011

Two Steps Forward and One Step Back for Precision in Prostate Cancer Treatment

scientific article published on 08 September 2020

Unconventional therapy for prostate cancer: good, bad or questionable?

scientific article published on November 2003

Upregulation of Scavenger Receptor B1 Is Required for Steroidogenic and Nonsteroidogenic Cholesterol Metabolism in Prostate Cancer

scientific article published on 07 May 2019

Urinary TMPRSS2:ERG and PCA3 in an active surveillance cohort: results from a baseline analysis in the Canary Prostate Active Surveillance Study

scientific article published on 20 March 2013

Use of aspirin and other nonsteroidal antiinflammatory medications in relation to prostate cancer risk

scientific article

VEGF/neuropilin-2 regulation of Bmi-1 and consequent repression of IGF-IR define a novel mechanism of aggressive prostate cancer

scientific article

Variability in the androgen response of prostate epithelium to 5alpha-reductase inhibition: implications for prostate cancer chemoprevention

scientific article

WDR19 expression is increased in prostate cancer compared with normal cells, but low-intensity expression in cancers is associated with shorter time to biochemical failures and local recurrence

scientific article

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