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List of works by Ajit G Thomas

Cambinol, a novel inhibitor of neutral sphingomyelinase 2 shows neuroprotective properties

scientific article

D-Amino-Acid Oxidase Inhibition Increases D-Serine Plasma Levels in Mouse But not in Monkey or Dog.

scientific article published on 16 October 2015

Design, synthesis, and pharmacological evaluation of bis-2-(5-phenylacetamido-1,2,4-thiadiazol-2-yl)ethyl sulfide 3 (BPTES) analogs as glutaminase inhibitors.

scientific article published on 30 November 2012

Development of a primary microglia screening assay and its use to characterize inhibition of system xc- by erastin and its analogs

scientific article published on 17 January 2017

Discovery of Benzamidine- and 1-Aminoisoquinoline-Based Human MAS-Related G-Protein-Coupled Receptor X1 (MRGPRX1) Agonists

scientific article published on 09 September 2019

Enhanced Brain Delivery of 2-(Phosphonomethyl)pentanedioic Acid Following Intranasal Administration of Its γ-Substituted Ester Prodrugs

scientific article

Glutamate carboxypeptidase II (NAALADase) inhibition as a novel therapeutic strategy

scientific article published on January 2006

Glutamate carboxypeptidase II inhibition protects motor neurons from death in familial amyotrophic lateral sclerosis models

scientific journal article

High-Throughput Assay Development for Cystine-Glutamate Antiporter (xc-) Highlights Faster Cystine Uptake than Glutamate Release in Glioma Cells

scientific article

Inhibition of NAALADase by 2-PMPA attenuates cocaine-induced relapse in rats: a NAAG-mGluR2/3-mediated mechanism

scientific article

Inhibition of neutral sphingomyelinase 2 promotes remyelination

scientific article published on 02 October 2020

Kinetic characterization of ebselen, chelerythrine and apomorphine as glutaminase inhibitors ⬇️

scientific article published on July 10, 2013

Oral administration of the NAALADase inhibitor GPI-5693 attenuates cocaine-induced reinstatement of drug-seeking behavior in rats.

scientific article

Palonosetron exhibits unique molecular interactions with the 5-HT3 receptor

scientific article

Pharmacokinetics of Intranasal versus Subcutaneous Insulin in the Mouse.

scientific article published on 19 December 2017

Pharmacokinetics of Oral d-Serine in d-Amino Acid Oxidase Knockout Mice ⬇️

scientific article published on July 26, 2012

Pharmacological inhibition of cystine-glutamate exchange induces endoplasmic reticulum stress and ferroptosis

scientific article

Small molecule glutaminase inhibitors block glutamate release from stimulated microglia

scientific article

Synthesis and SAR of 1-hydroxy-1H-benzo[d]imidazol-2(3H)-ones as Inhibitors of D-Amino Acid Oxidase.

scientific article

Synthesis of kojic acid derivatives as secondary binding site probes of D-amino acid oxidase

scientific article published on May 2013

The Antiemetic 5-HT3 Receptor Antagonist Palonosetron Inhibits Substance P-Mediated Responses In Vitro and In Vivo ⬇️

scientific article published on August 19, 2010

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