List of works - Emilia Entcheva

A comprehensive multiscale framework for simulating optogenetics in the heart.

scientific article published on January 2013

A sensitive algorithm for automatic detection of space-time alternating signals in cardiac tissue

scientific article

A step closer to cardiac optogenetics in vivo

scientific article published on 25 March 2015

A transmural gradient in the cardiac Na/K pump generates a transmural gradient in Na/Ca exchange

scientific article

Acoustic micromachining of three-dimensional surfaces for biological applications

scientific article published on 22 November 2004

Adeno-Associated Virus Mediated Gene Delivery: Implications for Scalable and Cardiac Optogenetic Models

article

All-Optical Electrophysiology Refines Populations of In Silico Human iPSC-CMs for Drug Evaluation

scientific article published on 04 April 2020

All-optical control of cardiac excitation: combined high-resolution optogenetic actuation and optical mapping

scientific article

Calcium instabilities in mammalian cardiomyocyte networks.

scientific article

Calpain-dependent cleavage of junctophilin-2 and T-tubule remodeling in a mouse model of reversible heart failure

scientific article

Cardiac Optogenetics: Enhancement by All-trans-Retinal

scientific article

Cardiac applications of optogenetics

scientific article published on 15 July 2014

Cardiac arrhythmogenesis and temperature.

scientific article published in January 2006

Cardiac cell networks on elastic microgrooved scaffolds

scientific article published in September 2003

Cardiac cellular coupling and the spread of early instabilities in intracellular Ca2+.

scientific article published on 20 March 2012

CellExcite: an efficient simulation environment for excitable cells

scientific article

Channelrhodopsin2 current during the action potential: "optical AP clamp" and approximation

scientific article published on 25 July 2014

Computational modeling of cardiac optogenetics: Methodology overview & review of findings from simulations

scientific article

Computational optogenetics: empirically-derived voltage- and light-sensitive channelrhodopsin-2 model

scientific article

Detecting space-time alternating biological signals close to the bifurcation point

scientific article

Effect of skeletal muscle Na(+) channel delivered via a cell platform on cardiac conduction and arrhythmia induction

scientific article

Electrospun fine-textured scaffolds for heart tissue constructs

scientific article

Expression of skeletal but not cardiac Na+ channel isoform preserves normal conduction in a depolarized cardiac syncytium.

scientific article published on 31 October 2008

Fiat lux in understanding cardiac pacing, resynchronization and signalling by way of optogenetics

scientific article published on 22 April 2014

Fluorescence imaging of electrical activity in cardiac cells using an all-solid-state system

scientific article published in February 2004

Functional cardiac cell constructs on cellulose-based scaffolding

scientific article

Hypertrophic phenotype in cardiac cell assemblies solely by structural cues and ensuing self-organization ⬇️

scientific article

Improving cardiac conduction with a skeletal muscle sodium channel by gene and cell therapy

scientific article

Inherent dispersion in restitution properties over space

scientific article

Inscribing Optical Excitability to Non-Excitable Cardiac Cells: Viral Delivery of Optogenetic Tools in Primary Cardiac Fibroblasts

scientific article published on January 2016

Lenses and effective spatial resolution in macroscopic optical mapping.

scientific article

Loss of cardiac phosphoinositide 3-kinase p110 alpha results in contractile dysfunction

scientific article published on 13 July 2009

Macroscopic optical mapping of excitation in cardiac cell networks with ultra-high spatiotemporal resolution.

scientific article

Mechanical and spatial determinants of cytoskeletal geodesic dome formation in cardiac fibroblasts

scientific article

Microfluidics-enabled 96-well perfusion system for high-throughput tissue engineering and long-term all-optical electrophysiology

scientific article published on 30 September 2020

Multimodal on-axis platform for all-optical electrophysiology with near-infrared probes in human stem-cell-derived cardiomyocytes

scientific article published on 05 March 2019

M³: Microscope-based maskless micropatterning with dry film photoresist

scientific article

Optical Interrogation of Sympathetic Neuronal Effects on Macroscopic Cardiomyocyte Network Dynamics

scientific article published on 01 July 2020

Optical control of excitation waves in cardiac tissue.

scientific article

OptoDyCE as an automated system for high-throughput all-optical dynamic cardiac electrophysiology.

scientific article

Optogenetic control of cardiomyocytes via viral delivery

scientific article

Optogenetic versus Electrical Stimulation of Human Cardiomyocytes: Modeling Insights

scientific article published on April 2015

Optogenetics' promise: pacing and cardioversion by light?

scientific article published on January 2014

Optogenetics-enabled assessment of viral gene and cell therapy for restoration of cardiac excitability.

scientific article

PI3Ks maintain the structural integrity of T-tubules in cardiac myocytes

scientific article (publication date: 2011)

Scaffold topography alters intracellular calcium dynamics in cultured cardiomyocyte networks

scientific article published on 22 April 2004

See the light: can optogenetics restore healthy heartbeats? And, if it can, is it really worth the effort?

scientific article published on 02 December 2013

Spatial frequency content in optical mapping of cardiac cell monolayers

scientific article published on 19 May 2006

Stimulating cardiac muscle by light: cardiac optogenetics by cell delivery

scientific article published on 9 August 2011

Syncytium cell growth increases Kir2.1 contribution in human iPSC-cardiomyocytes

scientific article published on 28 September 2020

The role of cardiac tissue alignment in modulating electrical function

scientific article published on 4 October 2007

Toward microendoscopy-inspired cardiac optogenetics in vivo: technical overview and perspective

scientific article published on August 2014

Uncovering an electrically heterogeneous cardiomyocyte by FRAP-quantified diffusion in the T-tubules

scientific article published on 5 January 2018

List of works by Emilia Entcheva

A comprehensive multiscale framework for simulating optogenetics in the heart.

A sensitive algorithm for automatic detection of space-time alternating signals in cardiac tissue

A step closer to cardiac optogenetics in vivo

A transmural gradient in the cardiac Na/K pump generates a transmural gradient in Na/Ca exchange

Acoustic micromachining of three-dimensional surfaces for biological applications

Adeno-Associated Virus Mediated Gene Delivery: Implications for Scalable and Cardiac Optogenetic Models

All-Optical Electrophysiology Refines Populations of In Silico Human iPSC-CMs for Drug Evaluation

All-optical control of cardiac excitation: combined high-resolution optogenetic actuation and optical mapping

Calcium instabilities in mammalian cardiomyocyte networks.

Calpain-dependent cleavage of junctophilin-2 and T-tubule remodeling in a mouse model of reversible heart failure

Cardiac Optogenetics: Enhancement by All-trans-Retinal

Cardiac applications of optogenetics

Cardiac arrhythmogenesis and temperature.

Cardiac cell networks on elastic microgrooved scaffolds

Cardiac cellular coupling and the spread of early instabilities in intracellular Ca2+.

CellExcite: an efficient simulation environment for excitable cells

Channelrhodopsin2 current during the action potential: "optical AP clamp" and approximation

Computational modeling of cardiac optogenetics: Methodology overview & review of findings from simulations

Computational optogenetics: empirically-derived voltage- and light-sensitive channelrhodopsin-2 model

Detecting space-time alternating biological signals close to the bifurcation point

Effect of skeletal muscle Na(+) channel delivered via a cell platform on cardiac conduction and arrhythmia induction

Electrospun fine-textured scaffolds for heart tissue constructs

Expression of skeletal but not cardiac Na+ channel isoform preserves normal conduction in a depolarized cardiac syncytium.

Fiat lux in understanding cardiac pacing, resynchronization and signalling by way of optogenetics

Fluorescence imaging of electrical activity in cardiac cells using an all-solid-state system

Functional cardiac cell constructs on cellulose-based scaffolding

Hypertrophic phenotype in cardiac cell assemblies solely by structural cues and ensuing self-organization ⬇️

Improving cardiac conduction with a skeletal muscle sodium channel by gene and cell therapy

Inherent dispersion in restitution properties over space

Inscribing Optical Excitability to Non-Excitable Cardiac Cells: Viral Delivery of Optogenetic Tools in Primary Cardiac Fibroblasts

Lenses and effective spatial resolution in macroscopic optical mapping.

Loss of cardiac phosphoinositide 3-kinase p110 alpha results in contractile dysfunction

Macroscopic optical mapping of excitation in cardiac cell networks with ultra-high spatiotemporal resolution.

Mechanical and spatial determinants of cytoskeletal geodesic dome formation in cardiac fibroblasts

Microfluidics-enabled 96-well perfusion system for high-throughput tissue engineering and long-term all-optical electrophysiology

Multimodal on-axis platform for all-optical electrophysiology with near-infrared probes in human stem-cell-derived cardiomyocytes

M³: Microscope-based maskless micropatterning with dry film photoresist

Optical Interrogation of Sympathetic Neuronal Effects on Macroscopic Cardiomyocyte Network Dynamics

Optical control of excitation waves in cardiac tissue.

OptoDyCE as an automated system for high-throughput all-optical dynamic cardiac electrophysiology.

Optogenetic control of cardiomyocytes via viral delivery

Optogenetic versus Electrical Stimulation of Human Cardiomyocytes: Modeling Insights

Optogenetics' promise: pacing and cardioversion by light?

Optogenetics-enabled assessment of viral gene and cell therapy for restoration of cardiac excitability.

PI3Ks maintain the structural integrity of T-tubules in cardiac myocytes

Scaffold topography alters intracellular calcium dynamics in cultured cardiomyocyte networks

See the light: can optogenetics restore healthy heartbeats? And, if it can, is it really worth the effort?

Spatial frequency content in optical mapping of cardiac cell monolayers

Stimulating cardiac muscle by light: cardiac optogenetics by cell delivery

Syncytium cell growth increases Kir2.1 contribution in human iPSC-cardiomyocytes

The role of cardiac tissue alignment in modulating electrical function

Toward microendoscopy-inspired cardiac optogenetics in vivo: technical overview and perspective

Uncovering an electrically heterogeneous cardiomyocyte by FRAP-quantified diffusion in the T-tubules