List of works - Tamás Freund

A flexible software tool for fitting the parameters of neuronal models.

scientific article published on 8 July 2013

A flexible, interactive software tool for fitting the parameters of neuronal models.

scientific article

Amyloid β induces interneuron-specific changes in the hippocampus of APPNL-F mice

scientific article published on 29 May 2020

Brainstem nucleus incertus controls contextual memory formation

scientific article published on 01 May 2019

CB1 receptor-dependent and -independent inhibition of excitatory postsynaptic currents in the hippocampus by WIN 55,212-2.

scientific article

Cell type-specific differences in chloride-regulatory mechanisms and GABA(A) receptor-mediated inhibition in rat substantia nigra

scientific journal article

Cellular and network mechanisms of cholinergically-induced transition between gamma and sharp wave – ripple network states in the hippocampus.

scientific article

Cellular and subcellular distribution of spinophilin, a PP1 regulatory protein that bundles F-actin in dendritic spines

scientific article published on November 2004

Cellular architecture and transmitter phenotypes of neurons of the mouse median raphe region

scientific article published on 04 April 2016

Co-transmission of acetylcholine and GABA regulates hippocampal states

scientific article published in Nature Communications

Comment on "Principles of connectivity among morphologically defined cell types in adult neocortex".

scientific article published in September 2016

Complex propagation patterns characterize human cortical activity during slow-wave sleep

scientific article

Control of excitatory synaptic transmission by capsaicin is unaltered in TRPV1 vanilloid receptor knockout mice

scientific article

Convergence of excitatory and inhibitory inputs onto CCK-containing basket cells in the CA1 area of the rat hippocampus

scientific article published in March 2004

DAG-sensitive and Ca(2+) permeable TRPC6 channels are expressed in dentate granule cells and interneurons in the hippocampal formation.

scientific article published on 29 November 2012

Differences in subthreshold resonance of hippocampal pyramidal cells and interneurons: the role of h-current and passive membrane characteristics

scientific article

Different input and output properties characterize parvalbumin-positive basket and Axo-axonic cells in the hippocampal CA3 subfield.

scientific article published on 27 June 2013

Distinct cannabinoid sensitive receptors regulate hippocampal excitation and inhibition.

scientific article

Distinct properties of two major excitatory inputs to hippocampal pyramidal cells: a computational study.

scientific article published in October 2005

Distinct synaptic properties of perisomatic inhibitory cell types and their different modulation by cholinergic receptor activation in the CA3 region of the mouse hippocampus

scientific article

Divergent in vivo activity of non-serotonergic and serotonergic VGluT3-neurones in the median raphe region

scientific article published on 29 March 2016

Downregulation of the CB1 cannabinoid receptor and related molecular elements of the endocannabinoid system in epileptic human hippocampus.

scientific article

Dynamic changes of CB1-receptor expression in hippocampi of epileptic mice and humans

scientific article

Early intraneuronal amyloid triggers neuron-derived inflammatory signaling in APP transgenic rats and human brain

scientific article published on 06 March 2020

Endocannabinoid signaling in rat somatosensory cortex: laminar differences and involvement of specific interneuron types

scientific article

Endocannabinoid transport tightly controls 2-arachidonoyl glycerol actions in the hippocampus: effects of low temperature and the transport inhibitor AM404.

scientific article

Endocannabinoid-mediated long-term depression of afferent excitatory synapses in hippocampal pyramidal cells and GABAergic interneurons.

scientific article

Enhanced expression of potassium-chloride cotransporter KCC2 in human temporal lobe epilepsy.

scientific article

Enzymatic machinery for endocannabinoid biosynthesis associated with calcium stores in glutamatergic axon terminals.

scientific article

Erratum: Selective inhibition of 2-AG hydrolysis enhances endocannabinoid signaling in hippocampus

scholarly article published in Nature Neuroscience

Excitement reduces inhibition via endocannabinoids.

scientific article

Extrinsic and local glutamatergic inputs of the rat hippocampal CA1 area differentially innervate pyramidal cells and interneurons.

scientific article published on 28 September 2011

GABAB and CB1 cannabinoid receptor expression identifies two types of septal cholinergic neurons

scientific article published in June 2005

GABAergic neurons of the medial septum lead the hippocampal network during theta activity.

scientific article published on June 2009

Glutamatergic input from specific sources influences the nucleus accumbens-ventral pallidum information flow

scientific article published on 05 June 2011

HippoUnit: A software tool for the automated testing and systematic comparison of detailed models of hippocampal neurons based on electrophysiological data

Hippocampal GABAergic synapses possess the molecular machinery for retrograde nitric oxide signaling

scientific article

Hippocampal Network Dynamics during Rearing Episodes.

scientific article

Identification of the sites of 2-arachidonoylglycerol synthesis and action imply retrograde endocannabinoid signaling at both GABAergic and glutamatergic synapses in the ventral tegmental area.

scientific article

Immunocytochemically defined interneuron populations in the hippocampus of mouse strains used in transgenic technology

scientific article

In vivo SPECT and ex vivo autoradiographic brain imaging of the novel selective CB1 receptor antagonist radioligand [125I]SD7015 in CB1 knock-out and wildtype mouse.

scientific article

In vivo laminar electrophysiology co-registered with histology in the hippocampus of patients with temporal lobe epilepsy.

scientific article

Input-output features of anatomically identified CA3 neurons during hippocampal sharp wave/ripple oscillation in vitro.

scientific article published on July 2013

Involvement of nitric oxide in depolarization-induced suppression of inhibition in hippocampal pyramidal cells during activation of cholinergic receptors.

scientific article published in September 2007

Laminar analysis of slow wave activity in humans.

scientific article

Long-term plasticity of endocannabinoid signaling induced by developmental febrile seizures.

scientific article published on August 2003

Loss and reorganization of calretinin-containing interneurons in the epileptic human hippocampus.

scientific article

Maintaining network activity in submerged hippocampal slices: importance of oxygen supply

scientific article published on January 2009

Mechanisms of sharp wave initiation and ripple generation.

scientific article published in August 2014

Mechanisms of sharp wave-ripple generation and autonomous replay in a hippocampal network model.

scientific article published on 8 July 2013

Median raphe controls acquisition of negative experience in the mouse

scientific article published on 01 November 2019

Median raphe region stimulation alone generates remote, but not recent fear memory traces.

scientific article published on 14 July 2017

Molecular architecture of the cannabinoid signaling system in the core of the nucleus accumbens

scientific article

Molecular composition of the endocannabinoid system at glutamatergic synapses.

scientific article

Multiple functions of endocannabinoid signaling in the brain.

scientific article

NMDA receptors in GABAergic synapses during postnatal development.

scientific article

NMDA receptors in hippocampal GABAergic synapses and their role in nitric oxide signaling

scientific article

Neuroligin 2 is expressed in synapses established by cholinergic cells in the mouse brain

scientific article

Neuroprotective effects of a novel kynurenic acid analogue in a transgenic mouse model of Huntington's disease.

scientific article published on 31 December 2010

New insights into the classification and nomenclature of cortical GABAergic interneurons

scientific article published on 6 February 2013

New silver-gold intensification method of diaminobenzidine for double-labeling immunoelectron microscopy.

scientific article published on 12 January 2011

Nitric oxide signaling modulates synaptic transmission during early postnatal development

scientific article

Optogenetic activation of septal cholinergic neurons suppresses sharp wave ripples and enhances theta oscillations in the hippocampus

scientific article

Parvalbumin-containing fast-spiking basket cells generate the field potential oscillations induced by cholinergic receptor activation in the hippocampus.

scientific article

Perisomatic inhibition.

scientific article published on October 2007

Petilla terminology: nomenclature of features of GABAergic interneurons of the cerebral cortex

scientific article

Phase segregation of medial septal GABAergic neurons during hippocampal theta activity.

scientific article

Physiological sharp wave-ripples and interictal events in vitro: what's the difference?

scientific article published on 2 January 2014

Populations of hippocampal inhibitory neurons express different levels of cytochrome c.

scientific article

Presynaptically located CB1 cannabinoid receptors regulate GABA release from axon terminals of specific hippocampal interneurons

scientific article (publication date: June 1999)

Properties of in vivo interictal spike generation in the human subiculum.

scientific article

Quantitative ultrastructural analysis of basket and axo-axonic cell terminals in the mouse hippocampus

scientific article published on 10 January 2014

Reciprocal inhibition of G-protein signaling is induced by CB(1) cannabinoid and GABA(B) receptor interactions in rat hippocampal membranes

scientific article

Redistribution of CB1 cannabinoid receptors in the acute and chronic phases of pilocarpine-induced epilepsy

scientific article

Selective inhibition of 2-AG hydrolysis enhances endocannabinoid signaling in hippocampus

scientific article

Simultaneous activation of gamma and theta network oscillations in rat hippocampal slice cultures

scientific article published in March 2002

Spike timing of distinct types of GABAergic interneuron during hippocampal gamma oscillations in vitro.

scientific article published in October 2004

Spinal endocannabinoids and CB1 receptors mediate C-fiber-induced heterosynaptic pain sensitization.

scientific article

The Effects of Realistic Synaptic Distribution and 3D Geometry on Signal Integration and Extracellular Field Generation of Hippocampal Pyramidal Cells and Inhibitory Neurons.

scientific article published on 8 November 2016

The ascending median raphe projections are mainly glutamatergic in the mouse forebrain.

scientific article

The epileptic human hippocampal cornu ammonis 2 region generates spontaneous interictal-like activity in vitro.

scientific article published on 18 September 2009

The physiological variability of channel density in hippocampal CA1 pyramidal cells and interneurons explored using a unified data-driven modeling workflow

scientific article published on 17 September 2018

The presence of pacemaker HCN channels identifies theta rhythmic GABAergic neurons in the medial septum.

scientific article published on 19 June 2008

Types and synaptic connections of hippocampal inhibitory neurons reciprocally connected with the medial septum

scientific article published in July 2008

List of works by Tamás Freund

A flexible software tool for fitting the parameters of neuronal models.

A flexible, interactive software tool for fitting the parameters of neuronal models.

Amyloid β induces interneuron-specific changes in the hippocampus of APPNL-F mice

Brainstem nucleus incertus controls contextual memory formation

CB1 receptor-dependent and -independent inhibition of excitatory postsynaptic currents in the hippocampus by WIN 55,212-2.

Cell type-specific differences in chloride-regulatory mechanisms and GABA(A) receptor-mediated inhibition in rat substantia nigra

Cellular and network mechanisms of cholinergically-induced transition between gamma and sharp wave – ripple network states in the hippocampus.

Cellular and subcellular distribution of spinophilin, a PP1 regulatory protein that bundles F-actin in dendritic spines

Cellular architecture and transmitter phenotypes of neurons of the mouse median raphe region

Co-transmission of acetylcholine and GABA regulates hippocampal states

Comment on "Principles of connectivity among morphologically defined cell types in adult neocortex".

Complex propagation patterns characterize human cortical activity during slow-wave sleep

Control of excitatory synaptic transmission by capsaicin is unaltered in TRPV1 vanilloid receptor knockout mice

Convergence of excitatory and inhibitory inputs onto CCK-containing basket cells in the CA1 area of the rat hippocampus

DAG-sensitive and Ca(2+) permeable TRPC6 channels are expressed in dentate granule cells and interneurons in the hippocampal formation.

Differences in subthreshold resonance of hippocampal pyramidal cells and interneurons: the role of h-current and passive membrane characteristics

Different input and output properties characterize parvalbumin-positive basket and Axo-axonic cells in the hippocampal CA3 subfield.

Distinct cannabinoid sensitive receptors regulate hippocampal excitation and inhibition.

Distinct properties of two major excitatory inputs to hippocampal pyramidal cells: a computational study.

Distinct synaptic properties of perisomatic inhibitory cell types and their different modulation by cholinergic receptor activation in the CA3 region of the mouse hippocampus

Divergent in vivo activity of non-serotonergic and serotonergic VGluT3-neurones in the median raphe region

Downregulation of the CB1 cannabinoid receptor and related molecular elements of the endocannabinoid system in epileptic human hippocampus.

Dynamic changes of CB1-receptor expression in hippocampi of epileptic mice and humans

Early intraneuronal amyloid triggers neuron-derived inflammatory signaling in APP transgenic rats and human brain

Endocannabinoid signaling in rat somatosensory cortex: laminar differences and involvement of specific interneuron types

Endocannabinoid transport tightly controls 2-arachidonoyl glycerol actions in the hippocampus: effects of low temperature and the transport inhibitor AM404.

Endocannabinoid-mediated long-term depression of afferent excitatory synapses in hippocampal pyramidal cells and GABAergic interneurons.

Enhanced expression of potassium-chloride cotransporter KCC2 in human temporal lobe epilepsy.

Enzymatic machinery for endocannabinoid biosynthesis associated with calcium stores in glutamatergic axon terminals.

Erratum: Selective inhibition of 2-AG hydrolysis enhances endocannabinoid signaling in hippocampus

Excitement reduces inhibition via endocannabinoids.

Extrinsic and local glutamatergic inputs of the rat hippocampal CA1 area differentially innervate pyramidal cells and interneurons.

GABAB and CB1 cannabinoid receptor expression identifies two types of septal cholinergic neurons

GABAergic neurons of the medial septum lead the hippocampal network during theta activity.

Glutamatergic input from specific sources influences the nucleus accumbens-ventral pallidum information flow

HippoUnit: A software tool for the automated testing and systematic comparison of detailed models of hippocampal neurons based on electrophysiological data

Hippocampal GABAergic synapses possess the molecular machinery for retrograde nitric oxide signaling

Hippocampal Network Dynamics during Rearing Episodes.

Identification of the sites of 2-arachidonoylglycerol synthesis and action imply retrograde endocannabinoid signaling at both GABAergic and glutamatergic synapses in the ventral tegmental area.

Immunocytochemically defined interneuron populations in the hippocampus of mouse strains used in transgenic technology

In vivo SPECT and ex vivo autoradiographic brain imaging of the novel selective CB1 receptor antagonist radioligand [125I]SD7015 in CB1 knock-out and wildtype mouse.

In vivo laminar electrophysiology co-registered with histology in the hippocampus of patients with temporal lobe epilepsy.

Input-output features of anatomically identified CA3 neurons during hippocampal sharp wave/ripple oscillation in vitro.

Involvement of nitric oxide in depolarization-induced suppression of inhibition in hippocampal pyramidal cells during activation of cholinergic receptors.

Laminar analysis of slow wave activity in humans.

Long-term plasticity of endocannabinoid signaling induced by developmental febrile seizures.

Loss and reorganization of calretinin-containing interneurons in the epileptic human hippocampus.

Maintaining network activity in submerged hippocampal slices: importance of oxygen supply

Mechanisms of sharp wave initiation and ripple generation.

Mechanisms of sharp wave-ripple generation and autonomous replay in a hippocampal network model.

Median raphe controls acquisition of negative experience in the mouse

Median raphe region stimulation alone generates remote, but not recent fear memory traces.

Molecular architecture of the cannabinoid signaling system in the core of the nucleus accumbens

Molecular composition of the endocannabinoid system at glutamatergic synapses.

Multiple functions of endocannabinoid signaling in the brain.

NMDA receptors in GABAergic synapses during postnatal development.

NMDA receptors in hippocampal GABAergic synapses and their role in nitric oxide signaling

Neuroligin 2 is expressed in synapses established by cholinergic cells in the mouse brain

Neuroprotective effects of a novel kynurenic acid analogue in a transgenic mouse model of Huntington's disease.

New insights into the classification and nomenclature of cortical GABAergic interneurons

New silver-gold intensification method of diaminobenzidine for double-labeling immunoelectron microscopy.

Nitric oxide signaling modulates synaptic transmission during early postnatal development

Optogenetic activation of septal cholinergic neurons suppresses sharp wave ripples and enhances theta oscillations in the hippocampus

Parvalbumin-containing fast-spiking basket cells generate the field potential oscillations induced by cholinergic receptor activation in the hippocampus.

Perisomatic inhibition.

Petilla terminology: nomenclature of features of GABAergic interneurons of the cerebral cortex

Phase segregation of medial septal GABAergic neurons during hippocampal theta activity.

Physiological sharp wave-ripples and interictal events in vitro: what's the difference?

Populations of hippocampal inhibitory neurons express different levels of cytochrome c.

Presynaptically located CB1 cannabinoid receptors regulate GABA release from axon terminals of specific hippocampal interneurons

Properties of in vivo interictal spike generation in the human subiculum.

Quantitative ultrastructural analysis of basket and axo-axonic cell terminals in the mouse hippocampus

Reciprocal inhibition of G-protein signaling is induced by CB(1) cannabinoid and GABA(B) receptor interactions in rat hippocampal membranes

Redistribution of CB1 cannabinoid receptors in the acute and chronic phases of pilocarpine-induced epilepsy

Selective inhibition of 2-AG hydrolysis enhances endocannabinoid signaling in hippocampus

Simultaneous activation of gamma and theta network oscillations in rat hippocampal slice cultures

Spike timing of distinct types of GABAergic interneuron during hippocampal gamma oscillations in vitro.

Spinal endocannabinoids and CB1 receptors mediate C-fiber-induced heterosynaptic pain sensitization.

The Effects of Realistic Synaptic Distribution and 3D Geometry on Signal Integration and Extracellular Field Generation of Hippocampal Pyramidal Cells and Inhibitory Neurons.