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List of works by Takashi Uchiyama

A case of HIV-associated lymphoproliferative disease that was successfully treated with highly active antiretroviral therapy

scientific article published on 10 March 2010

A phase I/IIa clinical trial of immunotherapy for elderly patients with acute myeloid leukaemia using dendritic cells co-pulsed with WT1 peptide and zoledronate

scientific article published on 08 April 2011

A prospective study of cyclosporine A treatment of patients with low-risk myelodysplastic syndrome: presence of CD55(-)CD59(-) blood cells predicts platelet response

scientific article published on 01 August 2007

APOBEC3G targets human T-cell leukemia virus type 1.

scientific article

APOBEC3G targets specific virus species.

scientific article published on August 2004

Altered homeostasis of CD4(+) memory T cells in allogeneic hematopoietic stem cell transplant recipients: chronic graft-versus-host disease enhances T cell differentiation and exhausts central memory T cell pool

scientific article published on 3 August 2007

Analysis of serum angiogenic factors in a young multiple myeloma patient with high-output cardiac failure

scientific article published on July 2007

Anti-interleukin 6 receptor antibody tocilizumab reduces the level of serum hepcidin in patients with multicentric Castleman's disease

scientific article published on 01 June 2007

Antibody responses associated with the graft-versus-leukemia effect in adult T-cell leukemia.

scientific article published in May 2006

Assessment of the international prognostic scoring system for determining chemotherapeutic indications in myelodysplastic syndrome: Japanese retrospective multicenter study

scientific article published on 01 October 2005

Association between interleukin-6 gene polymorphism and human T-cell leukemia virus type I associated myelopathy

scientific article

Atrial natriuretic peptide polarizes human dendritic cells toward a Th2-promoting phenotype through its receptor guanylyl cyclase-coupled receptor A.

scientific article

Augmentation of antitumour activity of defucosylated chimeric anti-CCR4 monoclonal antibody in SCID mouse model of adult T-cell leukaemia/lymphoma using G-CSF.

scientific article published on 16 January 2008

B7-H1 expression is regulated by MEK/ERK signaling pathway in anaplastic large cell lymphoma and Hodgkin lymphoma.

scientific article

Bortezomib suppresses function and survival of plasmacytoid dendritic cells by targeting intracellular trafficking of Toll-like receptors and endoplasmic reticulum homeostasis

scientific article published on 18 October 2010

Calpain-mediated X-linked inhibitor of apoptosis degradation in neutrophil apoptosis and its impairment in chronic neutrophilic leukemia

scientific article

Ceramide increases oxidative damage due to inhibition of catalase by caspase-3-dependent proteolysis in HL-60 cell apoptosis

scientific article

Characterization of t(3;6)(q27;p21) breakpoints in B-cell non-Hodgkin's lymphoma and construction of the histone H4/BCL6 fusion gene, leading to altered expression of Bcl-6

scientific article published on 01 November 2002

Clinical Significance of Serum Hepcidin Levels on Early Infectious Complications in Allogeneic Hematopoietic Stem Cell Transplantation

scientific article published on 01 August 2009

Clinical significance of subcategory and severity of chronic graft-versus-host disease evaluated by National Institutes of Health consensus criteria.

scientific article

Coexistent rearrangements of c-MYC, BCL2, and BCL6 genes in a diffuse large B-cell lymphoma

scientific article published in January 2004

Comparison of gene expression profiles of lymphoma cell lines from transformed follicular lymphoma, Burkitt's lymphoma and de novo diffuse large B-cell lymphoma

scientific article published on September 2003

Constitutive and functional association of the platelet collagen receptor glycoprotein VI-Fc receptor gamma-chain complex with membrane rafts

scientific article published in May 2002

Costimulation through OX40 is crucial for induction of an alloreactive human T-cell response

article

Cross-priming of CD8(+) T cells in vivo by dendritic cells pulsed with autologous apoptotic leukemic cells in immunotherapy for elderly patients with acute myeloid leukemia.

scientific article published on 7 January 2011

Crucial role of FOXP3 in the development and function of human CD25+CD4+ regulatory T cells

scientific article

Cyclin-dependent kinaselike 5 is a novel target of immunotherapy in adult T-cell leukemia

scientific article

Cyclosporin A therapy for patients with myelodysplastic syndrome: multicenter pilot studies in Japan

scientific article

Defucosylated humanized anti-CCR4 monoclonal antibody KW-0761 as a novel immunotherapeutic agent for adult T-cell leukemia/lymphoma.

scientific article

Delineation of immunoregulatory properties of adult T-cell leukemia cells

scientific article published on July 2006

Dendritic cells that endocytosed antigen-containing IgG-liposomes elicit effective antitumor immunity

scientific article published on 01 March 2006

Depletion and impaired interferon-alpha-producing capacity of blood plasmacytoid dendritic cells in human T-cell leukaemia virus type I-infected individuals.

scientific article published in June 2004

Disseminated Mycobacterium avium complex infection in a patient with autoantibody to interferon-gamma.

scientific article

Distinctive cell properties of B cells carrying the BCL2 translocation and their potential roles in the development of lymphoma of germinal center type

scientific article published on 02 September 2009

Distribution and kinetics of SR-PSOX/CXCL16 and CXCR6 expression on human dendritic cell subsets and CD4+ T cells

scientific article published on 9 February 2005

Durable hematological response and improvement of nephrotic syndrome on thalidomide therapy in a patient with refractory light chain deposition disease ⬇️

scientific article published on 09 April 2011

E148Q/M694I mutation in 3 Japanese patients with familial Mediterranean fever

scientific article published on April 2004

Effective treatment for de novo hepatitis B with nucleotide analogue in patients with hematological malignancies

scientific article

Effects of the Tyrosine Kinase Inhibitor Imatinib Mesylate on a Bcr-Abl-Positive Cell Line: Suppression of Autonomous Cell Growth but No Effect on Decreased Adhesive Property and Morphological Changes ⬇️

scientific article published on October 1, 2003

Epstein-Barr virus-associated B cell lymphoproliferative disorder complicated in adult T-cell leukemia

scientific article

Evaluation of the function of human invariant NKT cells from cancer patients using alpha-galactosylceramide-loaded murine dendritic cells

scientific article published on 01 September 2006

Expression of functional interleukin-21 receptor on adult T-cell leukaemia cells.

scientific article

FOXP3 expression in peripheral blood rapidly recovers and lacks correlation with the occurrence of graft-versus-host disease after allogeneic stem cell transplantation

scientific article published on 01 February 2007

Familial Mediterranean fever gene as a possible modifier of Sweet syndrome with chronic myelogenous leukemia

scientific article published on 30 September 2008

Feasibility of HLA-haploidentical hematopoietic stem cell transplantation between noninherited maternal antigen (NIMA)-mismatched family members linked with long-term fetomaternal microchimerism

scientific article published on 27 July 2004

For the further development of the International Journal of Hematology

scientific article published in February 2006

Foxp3-dependent and -independent molecules specific for CD25+CD4+ natural regulatory T cells revealed by DNA microarray analysis.

scientific article

Functional characterization of OX40 expressed on human CD8+ T cells

scientific article published on 25 April 2006

Growth and differentiation advantages of CD4+ OX40+ T cells from allogeneic hematopoietic stem cell transplantation recipients

scientific article published on 01 March 2008

HIV-1 viral infectivity factor interacts with TP53 to induce G2 cell cycle arrest and positively regulate viral replication.

scientific article published on 11 November 2010

High-level expression of BCL3 differentiates t(2;5)(p23;q35)-positive anaplastic large cell lymphoma from Hodgkin disease

scientific article published on 27 November 2002

Human plasmacytoid dendritic cells express an atrial natriuretic peptide receptor, guanylyl cyclase-A.

scientific article published in July 2009

Identification of APOBEC3B as a potential target for the graft-versus-lymphoma effect by SEREX in a patient with mantle cell lymphoma

scientific article published in August 2005

Identification of HLA class I-restricted tumor-associated antigens in adult T cell leukemia cells by mass spectrometric analysis.

scientific article published on November 2006

Identification of differentially expressed molecules in adult T-cell leukemia cells proliferating in vivo.

scientific article published on May 2004

IgE-activated mast cells in combination with pro-inflammatory factors induce Th2-promoting dendritic cells

scientific article published on 26 October 2006

Immunoglobulin (Ig)/BCL6 versus non-Ig/BCL6 gene fusion in diffuse large B-cell lymphoma corresponds to a high- versus low-level expression of BCL6 mRNA

scientific article published on 01 April 2002

Impact of ABO mismatching on the outcomes of allogeneic related and unrelated blood and marrow stem cell transplantations for hematologic malignancies: IPD-based meta-analysis of cohort studies

scientific article published on 2 January 2009

Impact of graft-versus-host disease on outcomes after allogeneic hematopoietic cell transplantation for adult T-cell leukemia: a retrospective cohort study

scientific article published on 10 January 2012

Increase of ceramide in adriamycin-induced HL-60 cell apoptosis: detection by a novel anti-ceramide antibody

scientific article published in October 2002

Increase of nuclear ceramide through caspase-3-dependent regulation of the "sphingomyelin cycle" in Fas-induced apoptosis

scientific article published in February 2004

Influence of cytokine and mannose binding protein gene polymorphisms on human T-cell leukemia virus type I (hTLV-I) provirus load in HTLV-I asymptomatic carriers

scientific article published in April 2003

Influence of radiation dose rate and lung dose on interstitial pneumonitis after fractionated total body irradiation: acute parotitis may predict interstitial pneumonitis

scientific article published on January 2006

Inhibition of cell growth by conditional expression of kpm, a human homologue of Drosophila warts/lats tumor suppressor

scientific article (publication date: 16 May 2003)

Introduction of OX40 ligand into lymphoma cells elicits anti-lymphoma immunity in vivo.

scientific article published on March 2005

Kpm/Lats2 is linked to chemosensitivity of leukemic cells through the stabilization of p73.

scientific article

LPS-induced ROS generation and changes in glutathione level and their relation to the maturation of human monocyte-derived dendritic cells

scientific article published on 8 November 2005

Lentiviral gp34/OX40L gene transfer into dendritic cells facilitates alloreactive CD4+ T-cell response in vitro

scientific article

MDM2 is a novel E3 ligase for HIV-1 Vif.

scientific article published on 07 January 2009

Molecular pathogenesis of Hodgkin lymphoma

scientific article published on June 2006

Murine retrovirus escapes from murine APOBEC3 via two distinct novel mechanisms.

scientific article published on August 2006

Myasthenia gravis after allogeneic bone marrow transplantation treated with mycophenolate mofetil monitored by peripheral blood OX40+ CD4+ T cells.

scientific article published in November 2002

Mycophenolate mofetil combined with tacrolimus and minidose methotrexate after unrelated donor bone marrow transplantation with reduced-intensity conditioning.

scientific article

NB4 cells treated with all-trans retinoic acid generate toxic reactive oxygen species that cause endothelial hyperpermeability

scientific article

Natural alpha interferon-producing cells respond to human immunodeficiency virus type 1 with alpha interferon production and maturation into dendritic cells

scientific article published on March 2003

Nitric oxide derived from human umbilical vein endothelial cells inhibits transendothelial migration of neutrophils

scientific article published on 01 April 2005

Nitric oxide inhibits IFN-alpha production of human plasmacytoid dendritic cells partly via a guanosine 3',5'-cyclic monophosphate-dependent pathway

scientific article

OX40 signaling renders adult T-cell leukemia cells resistant to Fas-induced apoptosis

scientific article published on October 2002

Oncostatin M and leukemia inhibitory factor increase hepcidin expression in hepatoma cell lines

scientific article

Optimal stimulation for CD70 induction on human monocyte-derived dendritic cells and the importance of CD70 in naive CD4(+) T-cell differentiation

scientific article published on 26 February 2010

Ozone production by amino acids contributes to killing of bacteria

scholarly article

PD-1-PD-1 ligand interaction contributes to immunosuppressive microenvironment of Hodgkin lymphoma.

scientific article

Phosphorylation of APOBEC3G by protein kinase A regulates its interaction with HIV-1 Vif.

scientific article published on 5 October 2008

Photodynamic effects of a novel pterin derivative on a pancreatic cancer cell line

scientific article published in August 2005

Possible role of ceramide as an indicator of chemoresistance: decrease of the ceramide content via activation of glucosylceramide synthase and sphingomyelin synthase in chemoresistant leukemia

scientific article published on January 2003

Potential of dendritic-cell immunotherapy for relapse after allogeneic hematopoietic stem cell transplantation, shown by WT1 peptide- and keyhole-limpet-hemocyanin-pulsed, donor-derived dendritic-cell vaccine for acute myeloid leukemia.

scientific article

Retrospective nationwide survey of Japanese patients with transfusion-dependent MDS and aplastic anemia highlights the negative impact of iron overload on morbidity/mortality

scientific article published on 28 March 2007

Retroviral transduction of acute myeloid leukaemia-derived dendritic cells with OX40 ligand augments their antigen presenting activity

scientific article published in February 2004

Reversible cardiomyopathy associated with Multicentric Castleman disease: successful treatment with tocilizumab, an anti-interleukin 6 receptor antibody.

scientific article published in April 2007

Serological identification of adult T-cell leukaemia-associated antigens.

scientific article published in August 2005

Serum hepcidin level and erythropoietic activity after hematopoietic stem cell transplantation

scientific article published on 18 July 2008

Short-term delay of Fas-stimulated apoptosis by GM-CSF as a result of temporary suppression of FADD recruitment in neutrophils: evidence implicating phosphatidylinositol 3-kinase and MEK1-ERK1/2 pathways downstream of classical protein kinase C

scientific article published on 24 August 2004

Signaling of gp34 (OX40 ligand) induces vascular endothelial cells to produce a CC chemokine RANTES/CCL5.

scientific article

Spatiotemporal regulation of moesin phosphorylation and rear release by Rho and serine/threonine phosphatase during neutrophil migration.

scientific article

Stimulation of CD30 in anaplastic large cell lymphoma leads to production of nuclear factor-kappaB p52, which is associated with hyperphosphorylated Bcl-3

scientific article

Successful allogeneic bone marrow transplantation for acute myelogenous leukemia after drug-induced cardiomyopathy

scientific article

Successful treatment with intravenous colistin for sinusitis, orbital cellulites, and pneumonia caused by multidrug-resistant metallo-beta-lactamase-producing Pseudomonas aeruginosa in a patient with acute myeloid leukemia

scientific article published on 24 March 2009

Successful treatment with paclitaxel of advanced AIDS-associated Kaposi's sarcoma

scientific article published on 01 December 2002

Sustained activation of MEK1-ERK1/2 pathway in membrane skeleton occurs dependently on cell adhesion in megakaryocytic differentiation

scientific article published on September 2002

The CD70-CD27 interaction during the stimulation with dendritic cells promotes naive CD4(+) T cells to develop into T cells producing a broad array of immunostimulatory cytokines in humans

scientific article published on 25 June 2009

The Rapid Induction of HLA-E Is Essential for the Survival of Antigen-Activated Naive CD4 T Cells from Attack by NK Cells ⬇️

scientific article published on October 15, 2010

The Serum Cytokine Profiles of Lymphoma-associated Hemophagocytic Syndrome: A Comparative Analysis of B-Cell and T-Cell/Natural Killer Cell Lymphomas ⬇️

scientific article published on 01 April 2003

The enzymatic activity of CEM15/Apobec-3G is essential for the regulation of the infectivity of HIV-1 virion but not a sole determinant of its antiviral activity.

scientific article

The expression and the regulatory role of OX40 and 4-1BB heterodimer in activated human T cells

scientific article

The gene for interleukin-21 receptor is the partner of BCL6 in t(3;16)(q27;p11), which is recurrently observed in diffuse large B-cell lymphoma

scientific article

The role of endothelial interleukin-8/NADPH oxidase 1 axis in sepsis

scientific article

Transplantation of allogeneic hematopoietic stem cells for adult T-cell leukemia: a nationwide retrospective study.

scientific article published on 17 May 2010

Type I interferons attenuate T cell activating functions of human mast cells by decreasing TNF-alpha production and OX40 ligand expression while increasing IL-10 production

scientific article published on 19 September 2006

Ubiquitination of APOBEC3 proteins by the Vif-Cullin5-ElonginB-ElonginC complex.

scientific article published on 21 November 2005

Ubiquitination of APOBEC3G by an HIV-1 Vif-Cullin5-Elongin B-Elongin C complex is essential for Vif function

scientific article

Vesnarinone causes oxidative damage by inhibiting catalase function through ceramide action in myeloid cell apoptosis

scientific article published in March 2002

Virus-stimulated plasmacytoid dendritic cells induce CD4+ cytotoxic regulatory T cells

scientific article

[Development of effective antigen delivery carrier to dendritic cells via Fc receptor in cancer immunotherapy]

scientific article published on 01 February 2007

[Hematology in the twentieth century and prospects for the twenty first century(discussion)]

scientific article published on 01 July 2002

[Significance of soluble interleukin-2 receptor alpha chain in the management of patients with malignant lymphoma: a multi-center study]

scientific article published on 01 March 2002

[Successful treatment of chronic myelogenous leukemia with extramedullary megakaryoblastic tumor by allogeneic bone marrow transplantation (from an unrelated donor)]

scientific article published on 01 May 2002

[Treatment of leukemia].

scientific article

alpha-Klotho as a regulator of calcium homeostasis

scientific article

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