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List of works by Radek Špíšek

Assessment of NK cell-mediated cytotoxicity by flow cytometry after rapid, high-yield isolation from peripheral blood

scientific article published on 27 June 2019

Bordetella adenylate cyclase toxin differentially modulates toll-like receptor-stimulated activation, migration and T cell stimulatory capacity of dendritic cells.

scientific article

Bortezomib enhances dendritic cell (DC)-mediated induction of immunity to human myeloma via exposure of cell surface heat shock protein 90 on dying tumor cells: therapeutic implications

scientific article published on 13 February 2007

Calreticulin and cancer

scientific article published on 30 July 2020

Calreticulin arms NK cells against leukemia

scientific article published on 09 October 2019

Calreticulin exposure by malignant blasts correlates with robust anticancer immunity and improved clinical outcome in AML patients

scientific article

Calreticulin exposure correlates with robust adaptive antitumor immunity and favorable prognosis in ovarian carcinoma patients

scientific article published on 20 November 2019

Calreticulin exposure on malignant blasts correlates with improved natural killer cell-mediated cytotoxicity in acute myeloid leukemia patients

scientific article published on 03 October 2019

Case report: type 1 diabetes in monozygotic quadruplets

scientific article published on 23 November 2011

Caspase-2 and oxidative stress underlie the immunogenic potential of high hydrostatic pressure-induced cancer cell death.

scientific article published on 18 November 2016

Classification of current anticancer immunotherapies

scientific article

Combinatorial strategies for the induction of immunogenic cell death

scientific article published on 24 April 2015

Consensus guidelines for the definition, detection and interpretation of immunogenic cell death

scientific article published on 01 March 2020

Consensus guidelines for the detection of immunogenic cell death

scientific article published on October 2014

Corrigendum: "Combinatorial Strategies for the Induction of Immunogenic Cell Death".

scientific article published on June 2015

Day 3 Poly (I:C)-activated dendritic cells generated in CellGro for use in cancer immunotherapy trials are fully comparable to standard Day 5 DCs

scientific article published on 12 April 2014

Decreased dendritic cell numbers but increased TLR9-mediated interferon-alpha production in first degree relatives of type 1 diabetes patients

scientific article published on 5 April 2014

Dendritic cells are specialized accessory cells along with TGF- for the differentiation of Foxp3+ CD4+ regulatory T cells from peripheral Foxp3 precursors

scientific article

Dendritic cells pulsed with tumor cells killed by high hydrostatic pressure inhibit prostate tumor growth in TRAMP mice

scientific article published on 24 August 2017

Detection of tumor antigens and tumor-antigen specific T cells in NSCLC patients: Correlation of the quality of T cell responses with NSCLC subtype

scientific article published on 10 January 2020

Frequent and specific immunity to the embryonal stem cell-associated antigen SOX2 in patients with monoclonal gammopathy

scientific article

Generation of dendritic cell-based vaccine using high hydrostatic pressure for non-small cell lung cancer immunotherapy

scientific article

Glucocorticoids severely impair differentiation and antigen presenting function of dendritic cells despite upregulation of Toll-like receptors.

scientific article

High hydrostatic pressure affects antigenic pool in tumor cells: Implication for dendritic cell-based cancer immunotherapy

scientific article

High hydrostatic pressure in cancer immunotherapy and biomedicine.

scientific article published on 30 January 2018

High hydrostatic pressure induces immunogenic cell death in human tumor cells

scientific article published on 20 February 2014

Immunoprevention of cancer

scientific article published on June 2006

Immunoprevention of cancer: time to reconsider timing of vaccination against cancer

scientific article published on 01 December 2006

Immunoprophylactic and immunotherapeutic control of hormone receptor-positive breast cancer

scientific article published on 30 July 2020

Induction of Tolerance and Immunity by Dendritic Cells: Mechanisms and Clinical Applications

scientific article published on 29 October 2019

Induction of leukemia-specific cytotoxic response by cross-presentation of late-apoptotic leukemic blasts by autologous dendritic cells of nonleukemic origin.

scientific article

Inflammation-associated lysophospholipids as ligands for CD1d-restricted T cells in human cancer

scientific article published on 5 June 2008

M2-like macrophages dictate clinically relevant immunosuppression in metastatic ovarian cancer

scientific article published on 01 August 2020

Maturation of dendritic cells by bacterial immunomodulators

scientific article published in July 2004

Maturation state of dendritic cells during the extracorporeal photopheresis and its relevance for the treatment of chronic graft-versus-host disease

scientific article published in January 2006

Mature dendritic cells correlate with favorable immune infiltrate and improved prognosis in ovarian carcinoma patients

scientific article published on 04 December 2018

Methods to assess DC-dependent priming of T cell responses by dying cells

scientific article published on 03 July 2019

Molecular and Translational Classifications of DAMPs in Immunogenic Cell Death

scientific article

Phase I/II clinical trial of dendritic-cell based immunotherapy (DCVAC/PCa) combined with chemotherapy in patients with metastatic, castration-resistant prostate cancer

scientific article

Phase I/II trial of dendritic cell-based active cellular immunotherapy with DCVAC/PCa in patients with rising PSA after primary prostatectomy or salvage radiotherapy for the treatment of prostate cancer.

scientific article published on 25 September 2017

Prognostic and Predictive Value of DAMPs and DAMP-Associated Processes in Cancer

scientific article

Publisher Correction: Immunoprophylactic and immunotherapeutic control of hormone receptor-positive breast cancer

scientific article published on 17 September 2020

Radiotherapy in Combination With Cytokine Treatment.

scientific article published on 22 May 2019

Relevance of the chaperone-like protein calreticulin for the biological behavior and clinical outcome of cancer

scientific article published on 22 November 2017

Role of teichoic acid choline moieties in the virulence of Streptococcus pneumoniae

scientific article published on 11 May 2009

Severe, but not mild heat-shock treatment induces immunogenic cell death in cancer cells

scientific article published on 31 March 2017

Side-by-side comparison of flow cytometry and immunohistochemistry for detection of calreticulin exposure in the course of immunogenic cell death

scientific article published on 08 July 2019

TIM-3 Dictates Functional Orientation of the Immune Infiltrate in Ovarian Cancer

scientific article published on 10 May 2019

Towards a better way to die with chemotherapy: role of heat shock protein exposure on dying tumor cells

scientific article

Transient exposure of dendritic cells to maturation stimuli is sufficient to induce complete phenotypic maturation while preserving their capacity to respond to subsequent restimulation ⬇️

scientific article published on April 17, 2003

Trial Watch-Immunostimulation with cytokines in cancer therapy

scientific article

Trial Watch-Oncolytic viruses and cancer therapy

scientific article

Trial Watch-Small molecules targeting the immunological tumor microenvironment for cancer therapy

scientific article published on 10 March 2016

Trial Watch: Adoptive cell transfer for oncological indications

scientific article

Trial Watch: Immunogenic cell death inducers for anticancer chemotherapy

scientific article

Trial Watch: Immunomodulatory monoclonal antibodies for oncological indications

scientific article

Trial Watch: Immunostimulation with recombinant cytokines for cancer therapy

scholarly article by Elena García-Martínez et al published 2018 in OncoImmunology

Trial Watch: Immunotherapy plus radiation therapy for oncological indications

scientific article published on 25 July 2016

Trial Watch: Oncolytic viro-immunotherapy of hematologic and solid tumors

scientific article published on 27 August 2018

Trial Watch: Toll-like receptor agonists in cancer immunotherapy

scientific article published on 11 October 2018

Trial watch: Dendritic cell-based anticancer therapy

scientific article

Trial watch: Immune checkpoint blockers for cancer therapy

scientific article published on 31 August 2017

Trial watch: Naked and vectored DNA-based anticancer vaccines

scientific article published on 2 April 2015

Trial watch: chemotherapy-induced immunogenic cell death in immuno-oncology

scientific article published on 09 January 2020

Trial watch: peptide-based vaccines in anticancer therapy

scientific article published on 06 September 2018

Tumour devascularisation as a potential immunotherapeutic strategy

scientific article published on 11 October 2018

Základy imunologie

book edition published in 2017

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