List of works - Fathia Mami-Chouaib

A three-dimensional tumor cell defect in activating autologous CTLs is associated with inefficient antigen presentation correlated with heat shock protein-70 down-regulation.

scientific article published in July 2003

AXL Targeting Overcomes Human Lung Cancer Cell Resistance to NK- and CTL-Mediated Cytotoxicity

scientific article published on 05 September 2019

Acquisition of tumor cell phenotypic diversity along the EMT spectrum under hypoxic pressure: Consequences on susceptibility to cell-mediated cytotoxicity.

scientific article published on 17 January 2017

Alpha E beta 7 integrin interaction with E-cadherin promotes antitumor CTL activity by triggering lytic granule polarization and exocytosis

scientific article

Analysis of the mechanisms of human cytotoxic T lymphocyte response inhibition by NO.

scientific article published in October 2002

Antitumor cytotoxic T-lymphocyte response in human lung carcinoma: identification of a tumor-associated antigen.

scientific article

Blocking hypoxia-induced autophagy in tumors restores cytotoxic T-cell activity and promotes regression.

scientific article

CD103 or LFA-1 Engagement at the Immune Synapse between Cytotoxic T Cells and Tumor Cells Promotes Maturation and Regulates T-cell Effector Functions ⬇️

scientific article published on November 27, 2012

CD8+CD103+ tumor-infiltrating lymphocytes are tumor-specific tissue-resident memory T cells and a prognostic factor for survival in lung cancer patients

scientific article published on 27 February 2015

Co-delivery of the NKT agonist α-galactosylceramide and tumor antigens to cross-priming dendritic cells breaks tolerance to self-antigens and promotes antitumor responses

scientific article published on 18 August 2017

Cross-reactivity between tumor MHC class I-restricted antigens and an enterococcal bacteriophage

scientific article published on 01 August 2020

Cutting Edge: NANOG Activates Autophagy under Hypoxic Stress by Binding to BNIP3L Promoter.

scientific article published on 16 January 2017

Cytotoxic T lymphocytes directed against a tumor-specific mutated antigen display similar HLA tetramer binding but distinct functional avidity and tissue distribution.

scientific article

Different expression levels of the TAP peptide transporter lead to recognition of different antigenic peptides by tumor-specific CTL.

scientific article

Drug specific cytotoxic T-cells in the skin lesions of a patient with toxic epidermal necrolysis.

scientific article published in April 2002

EMT impairs breast carcinoma cell susceptibility to CTL-mediated lysis through autophagy induction

scientific article published on 23 April 2013

Editorial: Tissue Resident Memory T Cells.

scientific article published on 27 May 2019

Endothelial cells as key determinants of the tumor microenvironment: interaction with tumor cells, extracellular matrix and immune killer cells

scientific article published on January 2010

Engagement of CD160 receptor by HLA-C is a triggering mechanism used by circulating natural killer (NK) cells to mediate cytotoxicity.

scientific article

Epithelial-to-mesenchymal transition and autophagy induction in breast carcinoma promote escape from T-cell-mediated lysis.

scientific article published on 22 February 2013

Functional and molecular characterization of a KIR3DL2/p140 expressing tumor-specific cytotoxic T lymphocyte clone infiltrating a human lung carcinoma

scientific article (publication date: 16 October 2003)

Gap junction communication between autologous endothelial and tumor cells induce cross-recognition and elimination by specific CTL.

scientific article

Generation of diverse mutated tumor antigen-specific cytotoxic T lymphocytes in a lung cancer patient with long survival

scientific article published on 01 September 2005

Granzyme B-activated p53 interacts with Bcl-2 to promote cytotoxic lymphocyte-mediated apoptosis.

scientific article

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

scientific article

Human CD5 protects circulating tumor antigen-specific CTL from tumor-mediated activation-induced cell death

scientific article published on June 2007

Human preprocalcitonin self-antigen generates TAP-dependent and -independent epitopes triggering optimised T-cell responses toward immune-escaped tumours

scientific article published in Nature Communications

Hypoxia-dependent inhibition of tumor cell susceptibility to CTL-mediated lysis involves NANOG induction in target cells

scientific article published on 12 September 2011

Hypoxia-induced autophagy: a new player in cancer immunotherapy?

scientific article published in April 2012

Hypoxia-inducible miR-210 regulates the susceptibility of tumor cells to lysis by cytotoxic T cells

scientific article published on 7 September 2012

Hypoxic tumor-derived microvesicles negatively regulate NK cell function by a mechanism involving TGF-β and miR23a transfer

scientific article

Identification of target actin content and polymerization status as a mechanism of tumor resistance after cytolytic T lymphocyte pressure

scholarly article

In situ sensory adaptation of tumor-infiltrating T lymphocytes to peptide-MHC levels elicits strong antitumor reactivity

scientific article

Intratumoral induction of CD103 triggers tumor-specific CTL function and CCR5-dependent T-cell retention

scientific article

Matrix architecture defines the preferential localization and migration of T cells into the stroma of human lung tumors

scientific article

Minimal Engagement of CD103 on Cytotoxic T Lymphocytes with an E-Cadherin-Fc Molecule Triggers Lytic Granule Polarization via a Phospholipase Cγ–Dependent Pathway ⬇️

scientific article published on January 11, 2011

Mutant alpha-actinin-4 promotes tumorigenicity and regulates cell motility of a human lung carcinoma

scientific article

NK cells infiltrating a MHC class I-deficient lung adenocarcinoma display impaired cytotoxic activity toward autologous tumor cells associated with altered NK cell-triggering receptors

scientific article published on November 2005

Paxillin Binding to the Cytoplasmic Domain of CD103 Promotes Cell Adhesion and Effector Functions for CD8+ Resident Memory T Cells in Tumors.

scientific article

Potentiation of NK cell-mediated cytotoxicity in human lung adenocarcinoma: role of NKG2D-dependent pathway

scientific article

Potentiation of a tumor cell susceptibility to autologous CTL killing by restoration of wild-type p53 function.

scientific article published on June 2003

Preprocalcitonin signal peptide generates a cytotoxic T lymphocyte-defined tumor epitope processed by a proteasome-independent pathway

scholarly article

Recent Advances in Lung Cancer Immunotherapy: Input of T-Cell Epitopes Associated With Impaired Peptide Processing

scientific article published on 03 July 2019

Recent Advances in Targeting CD8 T-Cell Immunity for More Effective Cancer Immunotherapy.

scientific article published on 22 January 2018

Regulation of antitumour CD8 T-cell immunity and checkpoint blockade immunotherapy by Neuropilin-1

scientific article published on 26 July 2019

Renal Cell Carcinoma Programmed Death-ligand 1, a New Direct Target of Hypoxia-inducible Factor-2 Alpha, is Regulated by von Hippel-Lindau Gene Mutation Status

scientific article published on 17 December 2015

Rescue of Tumor-Infiltrating Lymphocytes from Activation-Induced Cell Death Enhances the Antitumor CTL Response in CD5-Deficient Mice ⬇️

scientific article published on May 27, 2011

Resident memory T cells, critical components in tumor immunology

scientific article published on 04 September 2018

Resistance of tumor cells to cytolytic T lymphocytes involves Rho-GTPases and focal adhesion kinase activation.

scientific article published on 8 September 2008

Role of chemokines and chemokine receptors in shaping the effector phase of the antitumor immune response.

scientific article published on 07 December 2012

Role of p53 in the sensitization of tumor cells to apoptotic cell death

scientific article published on 01 May 2002

Smad and NFAT pathways cooperate to induce CD103 expression in human CD8 T lymphocytes

scientific article published on 29 January 2014

Synaptic release of CCL5 storage vesicles triggers CXCR4 surface expression promoting CTL migration in response to CXCL12.

scientific article published on 10 October 2014

T-cell modulatory properties of CD5 and its role in antitumor immune responses

scientific article published on January 2013

TAP expression level in tumor cells defines the nature and processing of MHC class I peptides for recognition by tumor-specific cytotoxic T lymphocytes

scientific article published on 09 January 2013

TGFβ Signaling Intersects with CD103 Integrin Signaling to Promote T-Lymphocyte Accumulation and Antitumor Activity in the Lung Tumor Microenvironment.

scientific article

The Emerging Role of CD8 Tissue Resident Memory T (T) Cells in Antitumor Immunity: A Unique Functional Contribution of the CD103 Integrin

scientific article published on 15 August 2018

The cooperative induction of hypoxia-inducible factor-1 alpha and STAT3 during hypoxia induced an impairment of tumor susceptibility to CTL-mediated cell lysis.

scientific article

The immune checkpoint ligand PD-L1 is upregulated in EMT-activated human breast cancer cells by a mechanism involving ZEB-1 and miR-200.

scientific article published on 23 January 2017

The multifaceted role of autophagy in tumor evasion from immune surveillance

scientific article published on 20 February 2016

Triggering of TLR7 and TLR8 expressed by human lung cancer cells induces cell survival and chemoresistance

scientific article

Tumor resistance to specific lysis: a major hurdle for successful immunotherapy of cancer

scientific article

Tumor-infiltrating CD4+ T lymphocytes express APO2 ligand (APO2L)/TRAIL upon specific stimulation with autologous lung carcinoma cells: role of IFN-alpha on APO2L/TRAIL expression and -mediated cytotoxicity

scientific article published on 01 July 2002

Tumor/cytotoxic effector cross-talk in the control of tumor susceptibility to lysis

scientific article published in August 2003

Wild-type p53 induced sensitization of mutant p53 TNF-resistant cells: role of caspase-8 and mitochondria

scientific article published in March 2002

[Immune response and cancer]

scientific article published on 01 January 2008

[Immunotherapy of cancer: promise and reality]

scientific article published on 01 August 2006

p53 potentiation of tumor cell susceptibility to CTL involves Fas and mitochondrial pathways.

scientific article

List of works by Fathia Mami-Chouaib

A three-dimensional tumor cell defect in activating autologous CTLs is associated with inefficient antigen presentation correlated with heat shock protein-70 down-regulation.

AXL Targeting Overcomes Human Lung Cancer Cell Resistance to NK- and CTL-Mediated Cytotoxicity

Acquisition of tumor cell phenotypic diversity along the EMT spectrum under hypoxic pressure: Consequences on susceptibility to cell-mediated cytotoxicity.

Alpha E beta 7 integrin interaction with E-cadherin promotes antitumor CTL activity by triggering lytic granule polarization and exocytosis

Analysis of the mechanisms of human cytotoxic T lymphocyte response inhibition by NO.

Antitumor cytotoxic T-lymphocyte response in human lung carcinoma: identification of a tumor-associated antigen.

Blocking hypoxia-induced autophagy in tumors restores cytotoxic T-cell activity and promotes regression.

CD103 or LFA-1 Engagement at the Immune Synapse between Cytotoxic T Cells and Tumor Cells Promotes Maturation and Regulates T-cell Effector Functions ⬇️

CD8+CD103+ tumor-infiltrating lymphocytes are tumor-specific tissue-resident memory T cells and a prognostic factor for survival in lung cancer patients

Co-delivery of the NKT agonist α-galactosylceramide and tumor antigens to cross-priming dendritic cells breaks tolerance to self-antigens and promotes antitumor responses

Cross-reactivity between tumor MHC class I-restricted antigens and an enterococcal bacteriophage

Cutting Edge: NANOG Activates Autophagy under Hypoxic Stress by Binding to BNIP3L Promoter.

Cytotoxic T lymphocytes directed against a tumor-specific mutated antigen display similar HLA tetramer binding but distinct functional avidity and tissue distribution.

Different expression levels of the TAP peptide transporter lead to recognition of different antigenic peptides by tumor-specific CTL.

Drug specific cytotoxic T-cells in the skin lesions of a patient with toxic epidermal necrolysis.

EMT impairs breast carcinoma cell susceptibility to CTL-mediated lysis through autophagy induction

Editorial: Tissue Resident Memory T Cells.

Endothelial cells as key determinants of the tumor microenvironment: interaction with tumor cells, extracellular matrix and immune killer cells

Engagement of CD160 receptor by HLA-C is a triggering mechanism used by circulating natural killer (NK) cells to mediate cytotoxicity.

Epithelial-to-mesenchymal transition and autophagy induction in breast carcinoma promote escape from T-cell-mediated lysis.

Functional and molecular characterization of a KIR3DL2/p140 expressing tumor-specific cytotoxic T lymphocyte clone infiltrating a human lung carcinoma

Gap junction communication between autologous endothelial and tumor cells induce cross-recognition and elimination by specific CTL.

Generation of diverse mutated tumor antigen-specific cytotoxic T lymphocytes in a lung cancer patient with long survival

Granzyme B-activated p53 interacts with Bcl-2 to promote cytotoxic lymphocyte-mediated apoptosis.

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Human CD5 protects circulating tumor antigen-specific CTL from tumor-mediated activation-induced cell death

Human preprocalcitonin self-antigen generates TAP-dependent and -independent epitopes triggering optimised T-cell responses toward immune-escaped tumours

Hypoxia-dependent inhibition of tumor cell susceptibility to CTL-mediated lysis involves NANOG induction in target cells

Hypoxia-induced autophagy: a new player in cancer immunotherapy?

Hypoxia-inducible miR-210 regulates the susceptibility of tumor cells to lysis by cytotoxic T cells

Hypoxic tumor-derived microvesicles negatively regulate NK cell function by a mechanism involving TGF-β and miR23a transfer

Identification of target actin content and polymerization status as a mechanism of tumor resistance after cytolytic T lymphocyte pressure

In situ sensory adaptation of tumor-infiltrating T lymphocytes to peptide-MHC levels elicits strong antitumor reactivity

Intratumoral induction of CD103 triggers tumor-specific CTL function and CCR5-dependent T-cell retention

Matrix architecture defines the preferential localization and migration of T cells into the stroma of human lung tumors

Minimal Engagement of CD103 on Cytotoxic T Lymphocytes with an E-Cadherin-Fc Molecule Triggers Lytic Granule Polarization via a Phospholipase Cγ–Dependent Pathway ⬇️

Mutant alpha-actinin-4 promotes tumorigenicity and regulates cell motility of a human lung carcinoma

NK cells infiltrating a MHC class I-deficient lung adenocarcinoma display impaired cytotoxic activity toward autologous tumor cells associated with altered NK cell-triggering receptors

Paxillin Binding to the Cytoplasmic Domain of CD103 Promotes Cell Adhesion and Effector Functions for CD8+ Resident Memory T Cells in Tumors.

Potentiation of NK cell-mediated cytotoxicity in human lung adenocarcinoma: role of NKG2D-dependent pathway

Potentiation of a tumor cell susceptibility to autologous CTL killing by restoration of wild-type p53 function.

Preprocalcitonin signal peptide generates a cytotoxic T lymphocyte-defined tumor epitope processed by a proteasome-independent pathway

Recent Advances in Lung Cancer Immunotherapy: Input of T-Cell Epitopes Associated With Impaired Peptide Processing

Recent Advances in Targeting CD8 T-Cell Immunity for More Effective Cancer Immunotherapy.

Regulation of antitumour CD8 T-cell immunity and checkpoint blockade immunotherapy by Neuropilin-1

Renal Cell Carcinoma Programmed Death-ligand 1, a New Direct Target of Hypoxia-inducible Factor-2 Alpha, is Regulated by von Hippel-Lindau Gene Mutation Status

Rescue of Tumor-Infiltrating Lymphocytes from Activation-Induced Cell Death Enhances the Antitumor CTL Response in CD5-Deficient Mice ⬇️

Resident memory T cells, critical components in tumor immunology

Resistance of tumor cells to cytolytic T lymphocytes involves Rho-GTPases and focal adhesion kinase activation.

Role of chemokines and chemokine receptors in shaping the effector phase of the antitumor immune response.

Role of p53 in the sensitization of tumor cells to apoptotic cell death

Smad and NFAT pathways cooperate to induce CD103 expression in human CD8 T lymphocytes

Synaptic release of CCL5 storage vesicles triggers CXCR4 surface expression promoting CTL migration in response to CXCL12.

T-cell modulatory properties of CD5 and its role in antitumor immune responses

TAP expression level in tumor cells defines the nature and processing of MHC class I peptides for recognition by tumor-specific cytotoxic T lymphocytes

TGFβ Signaling Intersects with CD103 Integrin Signaling to Promote T-Lymphocyte Accumulation and Antitumor Activity in the Lung Tumor Microenvironment.

The Emerging Role of CD8 Tissue Resident Memory T (T) Cells in Antitumor Immunity: A Unique Functional Contribution of the CD103 Integrin

The cooperative induction of hypoxia-inducible factor-1 alpha and STAT3 during hypoxia induced an impairment of tumor susceptibility to CTL-mediated cell lysis.

The immune checkpoint ligand PD-L1 is upregulated in EMT-activated human breast cancer cells by a mechanism involving ZEB-1 and miR-200.

The multifaceted role of autophagy in tumor evasion from immune surveillance

Triggering of TLR7 and TLR8 expressed by human lung cancer cells induces cell survival and chemoresistance

Tumor resistance to specific lysis: a major hurdle for successful immunotherapy of cancer

Tumor-infiltrating CD4+ T lymphocytes express APO2 ligand (APO2L)/TRAIL upon specific stimulation with autologous lung carcinoma cells: role of IFN-alpha on APO2L/TRAIL expression and -mediated cytotoxicity

Tumor/cytotoxic effector cross-talk in the control of tumor susceptibility to lysis

Wild-type p53 induced sensitization of mutant p53 TNF-resistant cells: role of caspase-8 and mitochondria

[Immune response and cancer]

[Immunotherapy of cancer: promise and reality]

p53 potentiation of tumor cell susceptibility to CTL involves Fas and mitochondrial pathways.