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Pharmacokinetics-Driven Optimization of 4(3 H)-Pyrimidinones as Phosphodiesterase Type 5 Inhibitors Leading to TPN171, a Clinical Candidate for the Treatment of Pulmonary Arterial Hypertension

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Description scientific article published on 08 May 2019
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author: Haji Akber Aisa  Zhen Wang  Jingshan Shen  Weiliang Zhu  Yechun Xu  Zhijian Xu 

Publication date May 8, 2019
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