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Malignant glioma cells use MHC class II transactivator (CIITA) promoters III and IV to direct IFN-gamma-inducible CIITA expression and can function as nonprofessional antigen presenting cells in endocytic processing and CD4(+) T-cell activation.

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Description scientific article published in December 2001
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author: Jack P. Antel 

Publication date December 1, 2001
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