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The alarmin cytokine, high mobility group box 1, is produced by viable cardiomyocytes and mediates the lipopolysaccharide-induced myocardial dysfunction via a TLR4/phosphatidylinositol 3-kinase gamma pathway.

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Description scientific article published on 18 December 2009
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author: Josef Penninger 

Publication date December 18, 2009
Language English
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