Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1.
scientific article published on 28 March 2018
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author: Zbigniew Zaslona, Ana S.H. Costa, Emily Hams, Martin S King, Joanna F. McGouran, Benedikt M. Kessler, Paul Meakin, Padraic G. Fallon, Stuart T Caldwell, Edmund R.S. Kunji, Christian Frezza, Albena Dinkova-Kostova, Richard C Hartley, Michael P. Murphy, Luke A. J. O'Neill, Marah C Runtsch, Lee M Booty
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