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Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1.

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Description scientific article published on 28 March 2018
Author/s

author: Emily Hams  Martin S King  Zbigniew Zaslona  Joanna F. McGouran  Paul Meakin  Luke A. J. O'Neill  Stuart T Caldwell  Padraic G. Fallon  Ana S.H. Costa  Christian Frezza  Richard C Hartley  Edmund R.S. Kunji  Lee M Booty  Marah C Runtsch  Benedikt M. Kessler  Michael P. Murphy  Albena Dinkova-Kostova 

Publication date March 28, 2018
Language English
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